| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Satoh, M Yamazak. Tumor necrosis factor stimulates DNA synthesis of mouse hepatocytes in primary culture and is suppressed by transforming growth factor beta and interleukin 6. Journal of cellular physiology. vol 150. issue 1. 1992-02-18. PMID:1730779. |
their time courses were similar to those by epidermal growth factor (egf) with about a 15 h lag period and a peak period of 24-48 h. this action of tnf was abrogated by dna polymerase alpha inhibitor, aphidicolin and blocked specifically by anti-tnf antibody. |
1992-02-18 |
2023-08-11 |
mouse |
| O J Owens, C Stewart, R E Leak. Growth factors in ovarian cancer. British journal of cancer. vol 64. issue 6. 1992-02-18. PMID:1764384. |
one hundred and seventy-four samples from 133 patients with ovarian cancer were examined for egf and tgf alpha. |
1992-02-18 |
2023-08-11 |
Not clear |
| O J Owens, C Stewart, R E Leak. Growth factors in ovarian cancer. British journal of cancer. vol 64. issue 6. 1992-02-18. PMID:1764384. |
egf was detected in only 27.6% of samples while tgf alpha was present in 88.5%. |
1992-02-18 |
2023-08-11 |
Not clear |
| O J Owens, C Stewart, R E Leak. Growth factors in ovarian cancer. British journal of cancer. vol 64. issue 6. 1992-02-18. PMID:1764384. |
the median values for tgf alpha presence were at least 10-fold greater than those of egf. |
1992-02-18 |
2023-08-11 |
Not clear |
| O J Owens, C Stewart, R E Leak. Growth factors in ovarian cancer. British journal of cancer. vol 64. issue 6. 1992-02-18. PMID:1764384. |
there was no statistical difference between either tgf alpha or egf levels and degree of differentiation of the tumours. |
1992-02-18 |
2023-08-11 |
Not clear |
| A Opgenorth, D Strayer, C Upton, G McFadde. Deletion of the growth factor gene related to EGF and TGF alpha reduces virulence of malignant rabbit fibroma virus. Virology. vol 186. issue 1. 1992-01-22. PMID:1309274. |
deletion of the growth factor gene related to egf and tgf alpha reduces virulence of malignant rabbit fibroma virus. |
1992-01-22 |
2023-08-11 |
rabbit |
| Y C Yeh, E R Burns, J Yeh, H W Ye. Synergistic effects of endothelin-1 (ET-1) and transforming growth factor alpha (TGF-alpha) or epidermal growth factor (EGF) on DNA replication and G1 to S phase transition. Bioscience reports. vol 11. issue 3. 1992-01-06. PMID:1958812. |
synergistic effects of endothelin-1 (et-1) and transforming growth factor alpha (tgf-alpha) or epidermal growth factor (egf) on dna replication and g1 to s phase transition. |
1992-01-06 |
2023-08-11 |
rat |
| R Pepperkok, P Lorenz, R Jakobi, W Ansorge, W Pyeri. Cell growth stimulation by EGF: inhibition through antisense-oligodeoxynucleotides demonstrates important role of casein kinase II. Experimental cell research. vol 197. issue 2. 1992-01-06. PMID:1959559. |
to address this question, growth-arrested primary human fibroblasts (imr-90) were exposed prior growth stimulation by epidermal growth factor (egf) to oligodeoxynucleotides complementary to the translation start region of mrnas coding for ckii alpha and beta subunits. |
1992-01-06 |
2023-08-11 |
human |
| L J Yang, G Baffy, S G Rhee, D Manning, C A Hansen, J R Williamso. Pertussis toxin-sensitive Gi protein involvement in epidermal growth factor-induced activation of phospholipase C-gamma in rat hepatocytes. The Journal of biological chemistry. vol 266. issue 33. 1991-12-26. PMID:1657996. |
a 41-kda gi protein alpha subunit was found to be present in the anti-plc-gamma immune complex after egf stimulation as shown by in vitro adp-ribosylation using [32p]nad+ and activated pertussis toxin. |
1991-12-26 |
2023-08-11 |
rat |
| L J Yang, G Baffy, S G Rhee, D Manning, C A Hansen, J R Williamso. Pertussis toxin-sensitive Gi protein involvement in epidermal growth factor-induced activation of phospholipase C-gamma in rat hepatocytes. The Journal of biological chemistry. vol 266. issue 33. 1991-12-26. PMID:1657996. |
the kinetics of association between plc-gamma with gi alpha protein reached a maximum after 1 min of incubation with egf. |
1991-12-26 |
2023-08-11 |
rat |
| L J Yang, G Baffy, S G Rhee, D Manning, C A Hansen, J R Williamso. Pertussis toxin-sensitive Gi protein involvement in epidermal growth factor-induced activation of phospholipase C-gamma in rat hepatocytes. The Journal of biological chemistry. vol 266. issue 33. 1991-12-26. PMID:1657996. |
antibodies specific for the egf receptor also coimmunoprecipitated a gi protein alpha subunit. |
1991-12-26 |
2023-08-11 |
rat |
| L J Yang, G Baffy, S G Rhee, D Manning, C A Hansen, J R Williamso. Pertussis toxin-sensitive Gi protein involvement in epidermal growth factor-induced activation of phospholipase C-gamma in rat hepatocytes. The Journal of biological chemistry. vol 266. issue 33. 1991-12-26. PMID:1657996. |
treatment of hepatocytes with egf caused first an increase and then a decrease in the amount of gi protein alpha subunit associated with the egf receptor. |
1991-12-26 |
2023-08-11 |
rat |
| L J Yang, G Baffy, S G Rhee, D Manning, C A Hansen, J R Williamso. Pertussis toxin-sensitive Gi protein involvement in epidermal growth factor-induced activation of phospholipase C-gamma in rat hepatocytes. The Journal of biological chemistry. vol 266. issue 33. 1991-12-26. PMID:1657996. |
in contrast, studies with cultured rat liver (wb) cells, a cell line in which egf stimulation of phosphoinositide hydrolysis is not inhibited by pertussis toxin, showed that a stable complex of gi alpha was not formed with either plc-gamma or egf receptor immunoprecipitates. |
1991-12-26 |
2023-08-11 |
rat |
| T Ishida, K Sugio, K Yokoyama, M Teteishi, T Oka, T Nishino, K Sugimach. [Immunohistochemical evidences of prognostic parameters associated with tumor development of pulmonary adenocarcinoma]. Nihon Geka Gakkai zasshi. vol 92. issue 9. 1991-12-23. PMID:1944164. |
of the examined tumors, 67% showed a high expression of transforming growth factor alpha (tgf alpha); 50% for epidermal growth factor (egf), 45% for egf receptor (egfr), and 30% for urokinase type plasminogen activator (upa). |
1991-12-23 |
2023-08-11 |
Not clear |
| T Ishida, K Sugio, K Yokoyama, M Teteishi, T Oka, T Nishino, K Sugimach. [Immunohistochemical evidences of prognostic parameters associated with tumor development of pulmonary adenocarcinoma]. Nihon Geka Gakkai zasshi. vol 92. issue 9. 1991-12-23. PMID:1944164. |
on the other hand, the high expression of upa was modulated by tgf alpha and/or egf. |
1991-12-23 |
2023-08-11 |
Not clear |
| S Werner, W K Roth, B Bates, M Goldfarb, P H Hofschneide. Fibroblast growth factor 5 proto-oncogene is expressed in normal human fibroblasts and induced by serum growth factors. Oncogene. vol 6. issue 11. 1991-12-18. PMID:1658709. |
in quiescent fibroblasts, expression of fgf-5 is strongly induced by serum and several growth factors such as platelet-derived growth factor (pdgf), epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha). |
1991-12-18 |
2023-08-11 |
human |
| M Korc, B Chandrasekar, G N Sha. Differential binding and biological activities of epidermal growth factor and transforming growth factor alpha in a human pancreatic cancer cell line. Cancer research. vol 51. issue 23 Pt 1. 1991-12-16. PMID:1933884. |
the binding characteristics and biological activities of epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha) were studied in t3m4 human pancreatic cancer cells. |
1991-12-16 |
2023-08-11 |
human |
| J Krätzschmar, B Haendler, G Langer, W Boidol, P Bringmann, A Alagon, P Donner, W D Schleunin. The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression. Gene. vol 105. issue 2. 1991-12-13. PMID:1937019. |
the largest forms (dspa alpha 1 and -alpha 2) contain a signal peptide, a finger (f), an epidermal growth factor (egf), a kringle, and a serine protease domain, whereas dspa beta and -gamma lack the f and f-egf domains, respectively. |
1991-12-13 |
2023-08-11 |
Not clear |
| P T Le, S Lazorick, L P Whichard, B F Haynes, K H Singe. Regulation of cytokine production in the human thymus: epidermal growth factor and transforming growth factor alpha regulate mRNA levels of interleukin 1 alpha (IL-1 alpha), IL-1 beta, and IL-6 in human thymic epithelial cells at a post-transcriptional level. The Journal of experimental medicine. vol 174. issue 5. 1991-12-13. PMID:1940795. |
in this study we have evaluated the effect of epidermal growth factor (egf), a growth factor for te cells, and its homologue transforming growth factor alpha (tgf-alpha), on primary cultures of normal human te cells for the levels of il-1 alpha, il-1 beta, il-6, and tgf-alpha mrna. |
1991-12-13 |
2023-08-11 |
human |
| B W Ennis, M E Lippman, R B Dickso. The EGF receptor system as a target for antitumor therapy. Cancer investigation. vol 9. issue 5. 1991-12-06. PMID:1933488. |
this is in view of the possibility that malignant cell proliferation may be controlled by various mechanisms instead of that which involves the egf receptor system, despite the expression of both egf receptor and tgf alpha in the same cell. |
1991-12-06 |
2023-08-11 |
Not clear |