| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Falette, M F Lefebvre, F Meggouh, M Eynard, E Garin, S Sae. Measurement of occupied and non-occupied epidermal growth factor receptor sites in 216 human breast cancer biopsies. Breast cancer research and treatment. vol 20. issue 3. 1992-06-02. PMID:1571570. |
egf and egf-like peptide tgf alpha bind and activate the same membrane receptor protein. |
1992-06-02 |
2023-08-11 |
human |
| V H Gattone, D A Sherman, D A Hinton, F W Niu, R T Topham, R M Klei. Epidermal growth factor in the neonatal mouse salivary gland and kidney. Biology of the neonate. vol 61. issue 1. 1992-05-28. PMID:1567929. |
the identification of egf-binding sites in the kidney and submandibular gland before the presence of egf suggests that an egf-like molecule such as transforming growth factor alpha (tgf-alpha) may be present as a potential ligand in these organs. |
1992-05-28 |
2023-08-11 |
mouse |
| P Braské. Healing of experimental colon anastomosis. The European journal of surgery. Supplement. : = Acta chirurgica. Supplement. issue 566. 1992-05-26. PMID:1725603. |
the following histologic investigations of the anastomotic area were made: conventional histology, immunohistology (with antibodies for type i, iii, iv and v collagen, fibronectin and laminin), enzyme-histochemistry (for sdh, ldh, glu-6-phdh, nadh, nadph, acid phosphatase, leucylaminopeptidase and gldh) and in-situ hybridizations with cdna clones (for pro alpha 1 (i) and pro alpha 1 (iii) collagens, fibronectin, egf and the egf-receptor). |
1992-05-26 |
2023-08-11 |
rat |
| R Ballotti, V Baron, N Gautier, P Hainaut, J C Scimeca, J Dolais-Kitabgi, R Lammers, J Schlessinger, A Ullrich, E Van Obberghe. Activation and regulation of the insulin receptor kinase. Diabete & metabolisme. vol 18. issue 1 Pt 2. 1992-05-21. PMID:1314199. |
for the insulin receptor and the egf receptor it is believed that ligand occupancy results in interactions within the heterotetrameric alpha 2 beta 2 insulin receptor or between monomeric egf receptors. |
1992-05-21 |
2023-08-11 |
human |
| Y Umekita, N Enokizono, Y Sagara, K Kuriwaki, T Takasaki, A Yoshida, H Yoshid. Immunohistochemical studies on oncogene products (EGF-R, c-erbB-2) and growth factors (EGF, TGF-alpha) in human breast cancer: their relationship to oestrogen receptor status, histological grade, mitotic index and nodal status. Virchows Archiv. A, Pathological anatomy and histopathology. vol 420. issue 4. 1992-05-21. PMID:1348890. |
in this investigation, 83 human mammary carcinomas were examined for the expression of oestrogen receptor (er), epidermal growth factor receptor (egf-r), epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha), c-erbb-2, histological grade, mitotic index and nodal status, all of which are reportedly prognostically significant factors (bloom and richardson 1957; baak et al. |
1992-05-21 |
2023-08-11 |
human |
| R L Sutherland, C S Lee, R S Feldman, E A Musgrov. Regulation of breast cancer cell cycle progression by growth factors, steroids and steroid antagonists. The Journal of steroid biochemistry and molecular biology. vol 41. issue 3-8. 1992-05-18. PMID:1562509. |
such a system has been developed for t-47d human breast cancer cells: quiescent or slowly proliferating cells maintained in a serum-free medium can be stimulated to increase their rate of cell cycle progression upon a single addition of insulin, igf-i, egf, tgf alpha or bfgf. |
1992-05-18 |
2023-08-11 |
human |
| J Jankowski, D Hopwood, K G Wormsle. Flow-cytometric analysis of growth-regulatory peptides and their receptors in Barrett's oesophagus and oesophageal adenocarcinoma. Scandinavian journal of gastroenterology. vol 27. issue 2. 1992-05-14. PMID:1348589. |
the latter samples were disaggregated and labelled with antibodies to epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha), and epidermal growth factor receptor (egf-r). |
1992-05-14 |
2023-08-11 |
Not clear |
| K Kawamoto, T Yamaguchi, S Watanabe, K Uchid. An androgen-dependent subclone derived from a mouse mammary tumor, Shionogi carcinoma 115, secretes a heparin-binding growth factor having an apparent molecular weight of 31,000 in response to androgen. Biochimica et biophysica acta. vol 1134. issue 3. 1992-05-14. PMID:1558842. |
fibroblast growth factors (fgfs), epidermal growth factor (egf) and transforming growth factor-alpha (tgf alpha) are stimulatory for the growth of sc2g cells in the absence of androgen. |
1992-05-14 |
2023-08-11 |
mouse |
| M P Schrey, H Monaghan, J R Hol. Interaction of paracrine factors during labour: interleukin-1 beta causes amplification of decidua cell prostaglandin F2 alpha production in response to bradykinin and epidermal growth factor. Prostaglandins, leukotrienes, and essential fatty acids. vol 45. issue 2. 1992-05-13. PMID:1561233. |
bradykinin also stimulated arachidonic acid release in decidual fibroblasts, an effect which was potentiated in the presence of epidermal growth factor (egf), but which was not accompanied by an increase in pgf2 alpha production. |
1992-05-13 |
2023-08-11 |
Not clear |
| M P Schrey, H Monaghan, J R Hol. Interaction of paracrine factors during labour: interleukin-1 beta causes amplification of decidua cell prostaglandin F2 alpha production in response to bradykinin and epidermal growth factor. Prostaglandins, leukotrienes, and essential fatty acids. vol 45. issue 2. 1992-05-13. PMID:1561233. |
decidual fibroblasts pretreated with il-1 manifest a 10-fold increase in pgf2 alpha production in response to bk and egf. |
1992-05-13 |
2023-08-11 |
Not clear |
| L B Nanney, D L Ellis, J Levine, L E Kin. Epidermal growth factor receptors in idiopathic and virally induced skin diseases. The American journal of pathology. vol 140. issue 4. 1992-05-11. PMID:1532884. |
the altered distribution of epidermal growth factor receptors (egf-r) in hyperproliferative skin lesions such as psoriasis vulgaris, seborrheic keratoses, acanthosis nigricans, ichthyosis, and others implies aberrant control of growth/proliferation by epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), and other growth factors/cytokines. |
1992-05-11 |
2023-08-11 |
Not clear |
| S E Wilson, Y G He, S A Lloy. EGF, EGF receptor, basic FGF, TGF beta-1, and IL-1 alpha mRNA in human corneal epithelial cells and stromal fibroblasts. Investigative ophthalmology & visual science. vol 33. issue 5. 1992-05-11. PMID:1559775. |
egf, egf receptor, basic fgf, tgf beta-1, and il-1 alpha mrna in human corneal epithelial cells and stromal fibroblasts. |
1992-05-11 |
2023-08-11 |
human |
| S E Wilson, Y G He, S A Lloy. EGF, EGF receptor, basic FGF, TGF beta-1, and IL-1 alpha mRNA in human corneal epithelial cells and stromal fibroblasts. Investigative ophthalmology & visual science. vol 33. issue 5. 1992-05-11. PMID:1559775. |
we sought to determine whether human corneal epithelial cells and stromal fibroblasts synthesize messenger rnas (mrna) coding for epidermal growth factor (egf), egf receptor, basic fibroblast growth factor (basic fgf), transforming growth factor-beta 1 (tgf-beta 1), and interleukin-1 alpha (il-1 alpha). |
1992-05-11 |
2023-08-11 |
human |
| R W Groves, M H Allen, D M MacDonal. Abnormal expression of epidermal growth factor receptor in cutaneous epithelial tumours. Journal of cutaneous pathology. vol 19. issue 1. 1992-05-07. PMID:1556270. |
epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) are important keratinocyte mitogens. |
1992-05-07 |
2023-08-11 |
Not clear |
| G L Ganser, G P Stricklin, L M Matrisia. EGF and TGF alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases. The International journal of developmental biology. vol 35. issue 4. 1992-04-28. PMID:1801870. |
egf and tgf alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases. |
1992-04-28 |
2023-08-11 |
mouse |
| G L Ganser, G P Stricklin, L M Matrisia. EGF and TGF alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases. The International journal of developmental biology. vol 35. issue 4. 1992-04-28. PMID:1801870. |
growth factors such as egf and tgf alpha are known to regulate the expression of mmps in a variety of systems. |
1992-04-28 |
2023-08-11 |
mouse |
| G L Ganser, G P Stricklin, L M Matrisia. EGF and TGF alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases. The International journal of developmental biology. vol 35. issue 4. 1992-04-28. PMID:1801870. |
lungs treated with egf or tgf alpha were larger than controls, yet displayed fewer branches along with markedly dilated end buds which lacked clefts, indicating that these growth factors inhibit normal lung branching. |
1992-04-28 |
2023-08-11 |
mouse |
| G L Ganser, G P Stricklin, L M Matrisia. EGF and TGF alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases. The International journal of developmental biology. vol 35. issue 4. 1992-04-28. PMID:1801870. |
taken together, these results provide evidence that the growth factors egf and tgf alpha guide lung development, at least in part, by inducing the expression of matrix-degrading metalloproteinases. |
1992-04-28 |
2023-08-11 |
mouse |
| P Blanc, H Etienne, M Daujat, I Fabre, F Zindy, J Domergue, C Astre, B Saint Aubert, H Michel, P Maure. Mitotic responsiveness of cultured adult human hepatocytes to epidermal growth factor, transforming growth factor alpha, and human serum. Gastroenterology. vol 102. issue 4 Pt 1. 1992-04-27. PMID:1532370. |
the present study was undertaken to evaluate the ability of human hepatocytes to respond in culture to various mitotic agents including epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha), or serum from patients with fulminant hepatitis. |
1992-04-27 |
2023-08-11 |
human |
| L Jimenez de Asua, M Goi. Prostaglandin F2 alpha decreases the affinity of epidermal growth factor receptors in Swiss mouse 3T3 cells via protein kinase C activation. FEBS letters. vol 299. issue 3. 1992-04-16. PMID:1312042. |
prostaglandin f2 alpha (pgf2 alpha) selectively decreases the binding of 125i-labelled epidermal growth factor ([125i]egf) to intact swiss 3t3 cells. |
1992-04-16 |
2023-08-11 |
mouse |