| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Flössel, T Luther, S Albrecht, M Kotzsch, M Mülle. Constitutive tissue factor expression of human breast cancer cell line MCF-7 is modulated by growth factors. European journal of cancer (Oxford, England : 1990). vol 28A. issue 12. 1992-12-04. PMID:1419297. |
epidermal growth factor (egf), transforming growth factor alpha (tgf alpha) and interleukin-1 (il-1) rapidly increased tissue factor expression of mcf-7 cells peaking at 6-8 h after starting point of incubation, as determined by clotting test, enzyme linked immunosorbent assay and flow cytometry. |
1992-12-04 |
2023-08-11 |
human |
| J A Hardin, D G Gal. The effect of TGF alpha on intestinal solute transport. Regulatory peptides. vol 39. issue 2-3. 1992-12-04. PMID:1438970. |
the effect of transforming growth factor alpha (tgf alpha) and epidermal growth factor (egf) on 3-o-methylglucose transport was examined in vitro under short-circuited conditions in stripped rabbit jejunum. |
1992-12-04 |
2023-08-11 |
rabbit |
| A J Stewart, B R Westley, F E Ma. Modulation of the proliferative response of breast cancer cells to growth factors by oestrogen. British journal of cancer. vol 66. issue 4. 1992-12-01. PMID:1419600. |
oestradiol increased the response of cells to the proliferative effects of epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha) and basic fibroblast growth factor (bfgf). |
1992-12-01 |
2023-08-11 |
Not clear |
| M Fukuoka, K Yasuda, S Taii, T Mor. Synergistic actions of cytokines and growth factors in enhancing porcine granulosa cell growth. Endocrinologia japonica. vol 39. issue 3. 1992-12-01. PMID:1425452. |
whereas il-2 (0.1-100 ng/ml) did not affect [3h]thymidine incorporation, tumor necrosis factor alpha (tnf alpha) stimulated [3h]thymidine incorporation by itself and reproduced the actions of il-1 to act synergistically with insulin, egf, or fgf. |
1992-12-01 |
2023-08-11 |
Not clear |
| D Fabbro, R Imber, K Huggel, W Baschon. Growth-promoting effect of a protein-free hemodialysate used in situations of hypoxia and for tissue repair as measured via stimulation of S6-kinase. Arzneimittel-Forschung. vol 42. issue 7. 1992-11-20. PMID:1418056. |
these cells preferably express receptors for epidermal growth factor (egf)/transforming growth factor alpha (tgf-alpha) or somatomedin c (smc = insulin like growth factor i resp. |
1992-11-20 |
2023-08-11 |
Not clear |
| J Mendelsoh. Epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies. Journal of the National Cancer Institute. Monographs. issue 13. 1992-11-06. PMID:1389685. |
we have produced anti-egf receptor monoclonal antibodies (mabs), which block the binding of egf and transforming growth factor alpha (tgf-alpha), and can prevent ligand-stimulated activation of egf receptor tyrosine kinase. |
1992-11-06 |
2023-08-11 |
human |
| T E Carey, L Laurikainen, T S Nair, T S Reinke, D E Coling, G T Wolf, C Van Waes, M Liebert, C Marcel. Regulation of expression and phosphorylation of A9/alpha 6 beta 4 integrin in normal and neoplastic keratinocytes. Journal of the National Cancer Institute. Monographs. issue 13. 1992-11-06. PMID:1389698. |
our results indicate that high expression of the alpha 6 beta 4 integrin is associated with conditions that favor migration and undifferentiated proliferation of normal keratinocytes and that malignant keratinocytes differ from normal keratinocytes by constitutive phosphorylation of beta 4 and by failure to downregulate beta 4 transcription in response to calcium in the presence of egf. |
1992-11-06 |
2023-08-11 |
Not clear |
| R Lupu, A Wellstein, J Sheridan, B W Ennis, G Zugmaier, D Katz, M E Lippman, R B Dickso. Purification and characterization of a novel growth factor from human breast cancer cells. Biochemistry. vol 31. issue 32. 1992-09-29. PMID:1324710. |
this factor was immunoprecipitated by an anti-tgf alpha polyclonal antibody and also had tgf alpha-like biological activity, as assayed by egf radioreceptor assay and anchorage-independent assays. |
1992-09-29 |
2023-08-11 |
human |
| P le Coutre, S Bock, G Jakse, P E Petride. Immunoreactive low-molecular-weight epidermal growth factor in urine of patients with renal cell carcinoma. Urological research. vol 20. issue 4. 1992-09-24. PMID:1509636. |
egf levels were expressed as urinary egf/creatinine ratios, and a highly significant decrease (alpha = 0.0005 by student's t-test) of urinary egf was found in the patient group prior to surgery. |
1992-09-24 |
2023-08-11 |
human |
| P le Coutre, S Bock, G Jakse, P E Petride. Immunoreactive low-molecular-weight epidermal growth factor in urine of patients with renal cell carcinoma. Urological research. vol 20. issue 4. 1992-09-24. PMID:1509636. |
the cancer patients also showed an additional loss of urinary egf after unilateral nephrectomy (alpha = 0.0005 by student's t-test). |
1992-09-24 |
2023-08-11 |
human |
| P C Ferriola, P Netteshei. Alterations in growth factor pathways in multistage carcinogenesis of rat tracheal epithelial cells. Journal of radiation research. vol 32 Suppl 2. 1992-09-24. PMID:1823364. |
therefore, decreased egf requirements in transformed rte cells could be explained by autocrine tgf alpha regulation. |
1992-09-24 |
2023-08-11 |
rat |
| T Endo, Y Uchida, H Matsumoto, N Suzuki, A Nomura, F Hirata, S Hasegaw. Regulation of endothelin-1 synthesis in cultured guinea pig airway epithelial cells by various cytokines. Biochemical and biophysical research communications. vol 186. issue 3. 1992-09-18. PMID:1510683. |
il-8, tnf alpha and tgf beta transiently increased the synthesis of et-1, while egf, pdgf and gm/csf promoted proliferation of et-1 synthesizing cells. |
1992-09-18 |
2023-08-11 |
Not clear |
| Y Kitano, E Okamoto, K Saito, Y Okan. Effects of several growth factors on cultured neurofibroma cells. Journal of dermatological science. vol 3. issue 3. 1992-09-11. PMID:1498092. |
the proliferation of cells derived from neurofibroma was stimulated by basic fibroblast growth factor (bfgf), epidermal growth factor (egf), and transforming growth factor alpha (tgf-alpha). |
1992-09-11 |
2023-08-11 |
Not clear |
| P C Ferriola, A T Robertson, D W Rusnak, R Diaugustine, P Netteshei. Epidermal growth factor dependence and TGF alpha autocrine growth regulation in primary rat tracheal epithelial cells. Journal of cellular physiology. vol 152. issue 2. 1992-08-28. PMID:1639864. |
we have examined dependence of primary rat tracheal epithelial (rte) on exogenous epidermal growth factor (egf) and determined whether a tgf alpha autocrine pathway is operating in these cells. |
1992-08-28 |
2023-08-11 |
rat |
| G Schultz, N Chegini, M Grant, P Khaw, S MacKa. Effects of growth factors on corneal wound healing. Acta ophthalmologica. Supplement. issue 202. 1992-08-26. PMID:1322013. |
endogenously produced peptide growth factors such as epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha), or transforming growth factor beta (tgf-beta) may play key roles in the natural wound healing process. |
1992-08-26 |
2023-08-11 |
human |
| A Singh, I Blench, H R Morris, L A Savoy, M J Ree. Synergistic interaction of growth factors and albumin in regulating estradiol synthesis in breast cancer cells. Molecular and cellular endocrinology. vol 85. issue 3. 1992-08-26. PMID:1634015. |
in this study we have examined the ability of albumin to influence the effect of growth factors (insulin-like growth factor-i (igf-i), epidermal growth factor (egf), transforming growth factor-alpha (tgf alpha)) and cytokines (interleukin (il)-1, il-6) on estradiol 17 beta-hydroxysteroid dehydrogenase activity in mcf-7 cells. |
1992-08-26 |
2023-08-11 |
Not clear |
| A Singh, I Blench, H R Morris, L A Savoy, M J Ree. Synergistic interaction of growth factors and albumin in regulating estradiol synthesis in breast cancer cells. Molecular and cellular endocrinology. vol 85. issue 3. 1992-08-26. PMID:1634015. |
egf or tgf alpha failed to stimulate estradiol 17 beta-hydroxysteroid dehydrogenase activity and no synergism with albumin was detected. |
1992-08-26 |
2023-08-11 |
Not clear |
| M D Basson, I M Modlin, J A Madr. Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor. The Journal of clinical investigation. vol 90. issue 1. 1992-08-24. PMID:1634605. |
alpha 1 subunit pools were decreased after egf treatment on collagen i but alpha 1 pools increased after egf treatment on laminin. |
1992-08-24 |
2023-08-11 |
human |
| M D Basson, I M Modlin, J A Madr. Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor. The Journal of clinical investigation. vol 90. issue 1. 1992-08-24. PMID:1634605. |
surface pools of alpha 2 subunits were increased following egf treatment whether cells were cultured on laminin or collagen i. |
1992-08-24 |
2023-08-11 |
human |
| M D Basson, I M Modlin, J A Madr. Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor. The Journal of clinical investigation. vol 90. issue 1. 1992-08-24. PMID:1634605. |
furthermore, a functional antibody to the alpha 2 subunit inhibited egf stimulation of migration over laminin without substantial effects on basal migration over laminin or collagen i. |
1992-08-24 |
2023-08-11 |
human |