| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R J Playford, A C Woodman, P Clark, P Watanapa, D Vesey, P H Deprez, R C Williamson, J Cala. Effect of luminal growth factor preservation on intestinal growth. Lancet (London, England). vol 341. issue 8849. 1993-05-03. PMID:8096559. |
epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) are secreted into the gut lumen. |
1993-05-03 |
2023-08-12 |
human |
| R J Playford, A C Woodman, P Clark, P Watanapa, D Vesey, P H Deprez, R C Williamson, J Cala. Effect of luminal growth factor preservation on intestinal growth. Lancet (London, England). vol 341. issue 8849. 1993-05-03. PMID:8096559. |
studies based on molecular size and bioactivity confirmed that fasting human jejunal juice destroys egf and tgf alpha. |
1993-05-03 |
2023-08-12 |
human |
| C E Lindsell, V Misra, B D Murph. Regulation of follistatin messenger ribonucleic acid in porcine granulosa cells by epidermal growth factor and the protein kinase-C pathway. Endocrinology. vol 132. issue 4. 1993-04-30. PMID:8462462. |
pma (10 nm) induced a time-dependent increase in follistatin mrna levels, with a maximal response at 2 h. follistatin gene expression was induced by a 2-h incubation with egf (3 nm), but not by lh (100 ng/ml), gnrh (10 nm) or prostaglandin f2 alpha (80 micrograms/ml). |
1993-04-30 |
2023-08-12 |
Not clear |
| T G Kennedy, K D Brown, T J Vaugha. Expression of the genes for the epidermal growth factor receptor and its ligands in porcine corpora lutea. Endocrinology. vol 132. issue 4. 1993-04-30. PMID:8462481. |
using reverse transcription-polymerase chain reaction (rt-pcr), transcripts for egf receptor and for egf, transforming growth factor-alpha (tgf alpha), amphiregulin (ar) and heparin binding-egf (hb-egf) were detected in porcine corpora lutea at day 4, 10 and 20 of the estrous cycle. |
1993-04-30 |
2023-08-12 |
human |
| T Ishikawa, T Fukuda, M Sugiyama, A Tarnawsk. Direct protective action of epidermal growth factor on isolated gastric mucosal surface epithelial cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 43. issue 4. 1993-04-15. PMID:1294264. |
egf 1.0 and 10.0 micrograms/ml alone without ethanol increased pge2 and 6 keto pgf1 alpha generation by sec. |
1993-04-15 |
2023-08-11 |
rat |
| O J Owens, R E Leak. Growth factor content in normal and benign ovarian tumours. European journal of obstetrics, gynecology, and reproductive biology. vol 47. issue 3. 1993-04-15. PMID:1294409. |
epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) content was measured in normal ovaries and benign ovarian tumours. |
1993-04-15 |
2023-08-11 |
Not clear |
| O J Owens, R E Leak. Growth factor content in normal and benign ovarian tumours. European journal of obstetrics, gynecology, and reproductive biology. vol 47. issue 3. 1993-04-15. PMID:1294409. |
the frequency of detection and levels of tgf alpha measured were significantly higher than those of egf in the normal ovary group (p < 0.001) and also in the benign ovarian group (p < 0.005). |
1993-04-15 |
2023-08-11 |
Not clear |
| K Pavelic, M Antonic, L Pavelic, J Pavelic, Z Pavelic, S Spavent. Human lung cancers growing on extracellular matrix: expression of oncogenes and growth factors. Anticancer research. vol 12. issue 6B. 1993-04-09. PMID:1363516. |
several oncoproteins (c-myc, c-ha-ras, c-erbb-2) and growth factors/receptors (egf, egf-r, tgf alpha) were immunostained. |
1993-04-09 |
2023-08-11 |
human |
| B G Nair, H M Rashed, T B Pate. Epidermal growth factor produces inotropic and chronotropic effects in rat hearts by increasing cyclic AMP accumulation. Growth factors (Chur, Switzerland). vol 8. issue 1. 1993-04-09. PMID:8383515. |
moreover, we have shown that the stimulation of adenylyl cyclase by egf in heart is mediated via activation of the stimulatory gtp binding regulatory protein gs alpha (nair et al., j. biol. |
1993-04-09 |
2023-08-12 |
rat |
| J Jankowski, D Hopwood, K G Wormsle. Expression of epidermal growth factor, transforming growth factor alpha and their receptor in gastro-oesophageal diseases. Digestive diseases (Basel, Switzerland). vol 11. issue 1. 1993-04-08. PMID:8443952. |
this article is a review of aspects of the expression of the regulatory peptides; epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha), and their receptor (egf-r) in the epithelium of the human oesophagus and stomach in health and disease. |
1993-04-08 |
2023-08-12 |
human |
| E A Mesri, R J Kreitman, Y M Fu, S E Epstein, I Pasta. Heparin-binding transforming growth factor alpha-Pseudomonas exotoxin A. A heparan sulfate-modulated recombinant toxin cytotoxic to cancer cells and proliferating smooth muscle cells. The Journal of biological chemistry. vol 268. issue 7. 1993-04-06. PMID:8444864. |
tgf alpha-pe40, a recombinant toxin in which transforming growth factor alpha (tgf alpha) is fused to a mutant form of pseudomonas exotoxin, is selectively cytotoxic to cells bearing epidermal growth factor (egf) receptors. |
1993-04-06 |
2023-08-12 |
Not clear |
| E A Mesri, R J Kreitman, Y M Fu, S E Epstein, I Pasta. Heparin-binding transforming growth factor alpha-Pseudomonas exotoxin A. A heparan sulfate-modulated recombinant toxin cytotoxic to cancer cells and proliferating smooth muscle cells. The Journal of biological chemistry. vol 268. issue 7. 1993-04-06. PMID:8444864. |
to study the effect of the heparin-binding domain in a chimeric toxin targeted to the egf receptor, we fused the dna sequence corresponding to the putative nh2-terminal heparin-binding (hb) domain of hb-egf to chimeric toxins composed of tgf alpha and two different recombinant forms of pseudomonas exotoxin (pe). |
1993-04-06 |
2023-08-12 |
Not clear |
| E A Mesri, R J Kreitman, Y M Fu, S E Epstein, I Pasta. Heparin-binding transforming growth factor alpha-Pseudomonas exotoxin A. A heparan sulfate-modulated recombinant toxin cytotoxic to cancer cells and proliferating smooth muscle cells. The Journal of biological chemistry. vol 268. issue 7. 1993-04-06. PMID:8444864. |
both of the toxins were eluted from heparin at 0.8 m nacl, in contrast to their respective tgf alpha toxins which were eluted at 0.15 m. binding studies on a431 cells showed that the hb-tgf alpha toxins bound to the egf receptor with an affinity similar to that of the tgf alpha toxins. |
1993-04-06 |
2023-08-12 |
Not clear |
| P Henttu, P Vihk. Growth factor regulation of gene expression in the human prostatic carcinoma cell line LNCaP. Cancer research. vol 53. issue 5. 1993-04-01. PMID:7679946. |
egf evoked these changes in a concentration- and time-dependent fashion, in both the presence and absence of serum and most likely through interactions with the epidermal growth factor receptor, inasmuch as similar effects were achieved by treating the cells with transforming growth factor alpha. |
1993-04-01 |
2023-08-12 |
human |
| P Henttu, P Vihk. Growth factor regulation of gene expression in the human prostatic carcinoma cell line LNCaP. Cancer research. vol 53. issue 5. 1993-04-01. PMID:7679946. |
in the presence of androgen, some of the effects of egf and transforming growth factor alpha on the levels of androgen-regulated mrnas may be due to down-regulation of the expression of the har gene. |
1993-04-01 |
2023-08-12 |
human |
| T J Vaughan, P S James, J C Pascall, K D Brow. Expression of the genes for TGF alpha, EGF and the EGF receptor during early pig development. Development (Cambridge, England). vol 116. issue 3. 1993-03-25. PMID:1289058. |
in the unfertilised pig oocyte, maternal transcripts for egf, but not for tgf alpha or the egf-r, were detected. |
1993-03-25 |
2023-08-11 |
Not clear |
| L W Chung, W Li, M E Gleave, J T Hsieh, H C Wu, R A Sikes, H E Zhau, M G Bandyk, C J Logothetis, J S Rubi. Human prostate cancer model: roles of growth factors and extracellular matrices. Journal of cellular biochemistry. Supplement. vol 16H. 1993-03-25. PMID:1289680. |
however, addition of bfgf, hgf and ngf, but not afgf, tgf beta, igf1, igf2, pdgf, egf, tgf alpha and kgf, stimulated anchorage-independent growth of prostate cells, a condition closely parallel to tumor formation in vivo. |
1993-03-25 |
2023-08-11 |
human |
| A Tarnawski, S Y Lu, J Stachura, I J Sarfe. Adaptation of gastric mucosa to chronic alcohol administration is associated with increased mucosal expression of growth factors and their receptor. Scandinavian journal of gastroenterology. Supplement. vol 193. 1993-03-24. PMID:1290059. |
epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) stimulate cells growth and proliferation in the gastric mucosa with noted trophic effect, protect the gastric mucosa against acute injury and accelerate healing of injured mucosa. |
1993-03-24 |
2023-08-11 |
rat |
| A Tarnawski, S Y Lu, J Stachura, I J Sarfe. Adaptation of gastric mucosa to chronic alcohol administration is associated with increased mucosal expression of growth factors and their receptor. Scandinavian journal of gastroenterology. Supplement. vol 193. 1993-03-24. PMID:1290059. |
many of these effects are exerted through egf and tgf alpha action on their common receptor (egfr). |
1993-03-24 |
2023-08-11 |
rat |
| A Tarnawski, S Y Lu, J Stachura, I J Sarfe. Adaptation of gastric mucosa to chronic alcohol administration is associated with increased mucosal expression of growth factors and their receptor. Scandinavian journal of gastroenterology. Supplement. vol 193. 1993-03-24. PMID:1290059. |
the aim of the present study was to determine the effect of chronic alcohol administration on cell proliferation and gastric mucosal expression and distribution of egf, tgf alpha and egfr. |
1993-03-24 |
2023-08-11 |
rat |