| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Nakajima, H Kuwayam. Effects of transforming growth factor alpha and beta on rabbit gastric epithelial cell proliferation: a preliminary report. Journal of clinical gastroenterology. vol 17 Suppl 1. 1994-02-17. PMID:8283006. |
the effects of epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), insulin-like growth factor-i (igf-i), and transforming growth factor beta (tgf beta) on tritiated thymidine incorporation into dna by rabbit gastric epithelial cells were investigated. |
1994-02-17 |
2023-08-12 |
rabbit |
| G A Piazza, J L Ritte. Involvement of transforming growth factor-alpha and its receptor in the growth response of cultured human epidermal cells to retinoic acid. Epithelial cell biology. vol 2. issue 4. 1994-01-31. PMID:8269032. |
decreased tgf alpha binding capacity is thought to be due to the ability of ra to stimulate tgf alpha, thereby resulting in egf receptor binding and internalization. |
1994-01-31 |
2023-08-12 |
human |
| J D Chen, J P Kim, K Zhang, Y Sarret, K C Wynn, R H Kramer, D T Woodle. Epidermal growth factor (EGF) promotes human keratinocyte locomotion on collagen by increasing the alpha 2 integrin subunit. Experimental cell research. vol 209. issue 2. 1994-01-24. PMID:8262138. |
epidermal growth factor (egf) promotes human keratinocyte locomotion on collagen by increasing the alpha 2 integrin subunit. |
1994-01-24 |
2023-08-12 |
human |
| K Shuai, A Ziemiecki, A F Wilks, A G Harpur, H B Sadowski, M Z Gilman, J E Darnel. Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature. vol 366. issue 6455. 1994-01-10. PMID:7504784. |
here we investigate the tyrosine phosphorylation events on stat and jak proteins after treatment of cells with ifns alpha and gamma and with epidermal growth factor (egf). |
1994-01-10 |
2023-08-12 |
Not clear |
| R J Coffey, M Romano, W H Polk, P J Dempse. Roles for transforming growth factor-alpha in gastric physiology and pathophysiology. The Yale journal of biology and medicine. vol 65. issue 6. 1994-01-06. PMID:1341072. |
tgf alpha and egfr, but not egf, are expressed in normal gastric mucosa. |
1994-01-06 |
2023-08-11 |
mouse |
| A Garne. Therapeutic potential of growth factors and their antagonists. The Yale journal of biology and medicine. vol 65. issue 6. 1994-01-06. PMID:1341074. |
this article describes studies with four peptides, epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), gastrin-releasing peptide/bombesin (grp), and gastrin. |
1994-01-06 |
2023-08-11 |
mouse |
| A Garne. Therapeutic potential of growth factors and their antagonists. The Yale journal of biology and medicine. vol 65. issue 6. 1994-01-06. PMID:1341074. |
although antagonism of egf (and thus tgf alpha) receptors and/or transducing mechanisms is frequently cited as a potential therapeutic approach to hyperproliferative diseases, blocking the action of tgf alpha, grp, or gastrin with neutralizing antibodies or receptor antagonists did not influence the growth of a wide range of solid tumors in nude mice. |
1994-01-06 |
2023-08-11 |
mouse |
| W L Garner, S Karmiol, J L Rodriguez, D J Smith, S H Pha. Phenotypic differences in cytokine responsiveness of hypertrophic scar versus normal dermal fibroblasts. The Journal of investigative dermatology. vol 101. issue 6. 1994-01-06. PMID:8245516. |
the mitogenic responses of scar cells to fetal bovine serum, epidermal growth factor (egf), platelet-derived growth factor (pdgf), and tumor necrosis factor alpha (tnf alpha) were determined and compared to normal skin cells. |
1994-01-06 |
2023-08-12 |
cattle |
| D P Eisinger, H P Jiang, G Serrer. A novel mouse gene highly conserved throughout evolution: regulation in adipocyte differentiation and in tumorigenic cell lines. Biochemical and biophysical research communications. vol 196. issue 3. 1994-01-04. PMID:8250879. |
clone 168 mrna decreases 80% in rat primary culture of adipocytes compared to preadipocytes and does not decrease when differentiation is blocked by pgf2 alpha or egf, indicating that the decrease is correlated with expression of the differentiation phenotype. |
1994-01-04 |
2023-08-12 |
mouse |
| T Kobayashi, K Honke, S Gasa, S Imai, J Tanaka, T Miyazaki, A Makit. Regulation of activity levels of glycolipid sulfotransferases by transforming growth factor alpha in renal cell carcinoma cells. Cancer research. vol 53. issue 23. 1994-01-03. PMID:7902207. |
among the growth factors tested, transforming growth factor alpha (tgf-alpha) and epidermal growth factor (egf) were found to increase the sulfotransferase activity markedly (about 300%), but did not change that of arylsulfatase a, which hydrolyzes sulfoglycolipids. |
1994-01-03 |
2023-08-12 |
human |
| E van der Zee, V Everts, K Hoeben, W Beertse. Interleukin-1 alpha and epidermal growth factor synergistically enhance the release of collagenase by periosteal connective tissue in vitro. Matrix (Stuttgart, Germany). vol 13. issue 5. 1994-01-03. PMID:8246834. |
the effects of recombinant human interleukin-1 alpha (il-1 alpha) and murine epidermal growth factor (egf) on the release of collagenase were studied in an in vitro model system using periosteal explants from rabbit calvariae. |
1994-01-03 |
2023-08-12 |
human |
| E van der Zee, V Everts, K Hoeben, W Beertse. Interleukin-1 alpha and epidermal growth factor synergistically enhance the release of collagenase by periosteal connective tissue in vitro. Matrix (Stuttgart, Germany). vol 13. issue 5. 1994-01-03. PMID:8246834. |
following an incubation period of 72 h it was shown that il-1 alpha in combination with egf (il-1 alpha + egf) induced a synergistic increase in the amount of collagenase released by periosteal explants. |
1994-01-03 |
2023-08-12 |
human |
| E van der Zee, V Everts, K Hoeben, W Beertse. Interleukin-1 alpha and epidermal growth factor synergistically enhance the release of collagenase by periosteal connective tissue in vitro. Matrix (Stuttgart, Germany). vol 13. issue 5. 1994-01-03. PMID:8246834. |
a neutralizing anti-il-1 alpha antibody completely blocked the enhanced release of collagenase as induced both by il-1 alpha and by il-1 alpha + egf. |
1994-01-03 |
2023-08-12 |
human |
| E van der Zee, V Everts, K Hoeben, W Beertse. Interleukin-1 alpha and epidermal growth factor synergistically enhance the release of collagenase by periosteal connective tissue in vitro. Matrix (Stuttgart, Germany). vol 13. issue 5. 1994-01-03. PMID:8246834. |
it is suggested that the concomitant presence of the cytokines il-1 alpha and egf may play an important role in collagenase-mediated degradation of collagen. |
1994-01-03 |
2023-08-12 |
human |
| K Kofuji, K Hashimoto, I Kodama, K Aoyagi, J Ota, J Takeda, T Kakegaw. [Expression of the growth factors (EGF, EGFR, and TGF alpha) and PCNA in superspreading and penetrating types of gastric carcinomas]. Nihon Geka Gakkai zasshi. vol 94. issue 9. 1993-12-28. PMID:7902525. |
[expression of the growth factors (egf, egfr, and tgf alpha) and pcna in superspreading and penetrating types of gastric carcinomas]. |
1993-12-28 |
2023-08-12 |
Not clear |
| K Kofuji, K Hashimoto, I Kodama, K Aoyagi, J Ota, J Takeda, T Kakegaw. [Expression of the growth factors (EGF, EGFR, and TGF alpha) and PCNA in superspreading and penetrating types of gastric carcinomas]. Nihon Geka Gakkai zasshi. vol 94. issue 9. 1993-12-28. PMID:7902525. |
egf, egfr, and tgf alpha positive cases were preferentially found in the penetrating type rather than in the superspreading type (p < 0.05). |
1993-12-28 |
2023-08-12 |
Not clear |
| K Kofuji, K Hashimoto, I Kodama, K Aoyagi, J Ota, J Takeda, T Kakegaw. [Expression of the growth factors (EGF, EGFR, and TGF alpha) and PCNA in superspreading and penetrating types of gastric carcinomas]. Nihon Geka Gakkai zasshi. vol 94. issue 9. 1993-12-28. PMID:7902525. |
one case of the superspreading type and 13 cases of the penetrating type were either egf (+) or tgf alpha (+), and egfr (+), and the incidence in the latter type was significantly higher than that in the former type (p < 0.05), suggesting that growth and invasion of carcinoma cells, especially in the penetrating type, may depend on "autocrine mechanism". |
1993-12-28 |
2023-08-12 |
Not clear |
| J D King, S P Stringer, N Chegini, W H Donnelly, N J Cassisi, G S Schult. TGF-alpha protein and receptor localization in laryngotracheal tissue. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. vol 109. issue 5. 1993-12-28. PMID:8247573. |
specific binding to the egf/tgf alpha receptor in membrane homogenates of ferret larynx and trachea reached saturation after 60 minutes at 37 degrees c, and was effectively displaced by unlabeled epidermal growth factor (egf) or tgf alpha, but not by unlabeled insulin, angiotensin ii, or basic fibroblast growth factor. |
1993-12-28 |
2023-08-12 |
Not clear |
| D C Johnson, S Chatterje. Epidermal growth factor (EGF) replaces estradiol for the initiation of embryo implantation in the hypophysectomized rat. Placenta. vol 14. issue 4. 1993-12-27. PMID:8248035. |
several studies have provided evidence that epidermal growth factor (egf) or transforming growth factor alpha (tgf alpha) mediate some of the physiological effects of estrogen. |
1993-12-27 |
2023-08-12 |
rat |
| D C Johnson, S Chatterje. Epidermal growth factor (EGF) replaces estradiol for the initiation of embryo implantation in the hypophysectomized rat. Placenta. vol 14. issue 4. 1993-12-27. PMID:8248035. |
immunocytochemical examination showed the presence of immunoreactive egf, tgf alpha and the egf receptor in luminal glandular epithelium of uteri on days 4,5 and 6 of pregnancy. |
1993-12-27 |
2023-08-12 |
rat |