| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Tanno, K Ogaw. Abundant TGF alpha precursor and EGF receptor expression as a possible mechanism for the preferential growth of carcinogen-induced preneoplastic and neoplastic hepatocytes in rats. Carcinogenesis. vol 15. issue 8. 1994-09-15. PMID:7914477. |
abundant tgf alpha precursor and egf receptor expression as a possible mechanism for the preferential growth of carcinogen-induced preneoplastic and neoplastic hepatocytes in rats. |
1994-09-15 |
2023-08-12 |
rat |
| T A Voyno-Yasenetskaya, A M Pace, H R Bourn. Mutant alpha subunits of G12 and G13 proteins induce neoplastic transformation of Rat-1 fibroblasts. Oncogene. vol 9. issue 9. 1994-09-15. PMID:8058319. |
mitogen-activated protein (map) kinase activity, stimulated by egf, was increased in rat-1 cells that expressed mutant alpha 12 or alpha 13. |
1994-09-15 |
2023-08-12 |
human |
| E van der Zee, V Everts, K Hoeben, W Beertse. Immunolocalisation of collagenase in rabbit periosteal tissue explants and extraction of the enzyme. The effect of the cytokines IL-1 alpha and EGF. Journal of cell science. vol 107 ( Pt 4). 1994-09-13. PMID:8056829. |
the effect of the cytokines il-1 alpha and egf. |
1994-09-13 |
2023-08-12 |
rabbit |
| E van der Zee, V Everts, K Hoeben, W Beertse. Immunolocalisation of collagenase in rabbit periosteal tissue explants and extraction of the enzyme. The effect of the cytokines IL-1 alpha and EGF. Journal of cell science. vol 107 ( Pt 4). 1994-09-13. PMID:8056829. |
the effect of interleukin-1 alpha (il-1 alpha) and murine epidermal growth factor (egf) on incorporation of endogenously produced collagenase in the extracellular matrix of soft connective tissue was studied in an in vitro model system using periosteal explants obtained from rabbit calvariae. |
1994-09-13 |
2023-08-12 |
rabbit |
| E van der Zee, V Everts, K Hoeben, W Beertse. Immunolocalisation of collagenase in rabbit periosteal tissue explants and extraction of the enzyme. The effect of the cytokines IL-1 alpha and EGF. Journal of cell science. vol 107 ( Pt 4). 1994-09-13. PMID:8056829. |
immunohistochemical analysis indicated the highest level of collagenase in explants cultured for 72 hours with il-1 alpha in combination with egf. |
1994-09-13 |
2023-08-12 |
rabbit |
| E van der Zee, V Everts, K Hoeben, W Beertse. Immunolocalisation of collagenase in rabbit periosteal tissue explants and extraction of the enzyme. The effect of the cytokines IL-1 alpha and EGF. Journal of cell science. vol 107 ( Pt 4). 1994-09-13. PMID:8056829. |
explants cultured in the presence of il-1 alpha alone contained less enzyme and in periostea treated without cytokines, or with egf alone, only a faint label, if any, was seen. |
1994-09-13 |
2023-08-12 |
rabbit |
| E van der Zee, V Everts, K Hoeben, W Beertse. Immunolocalisation of collagenase in rabbit periosteal tissue explants and extraction of the enzyme. The effect of the cytokines IL-1 alpha and EGF. Journal of cell science. vol 107 ( Pt 4). 1994-09-13. PMID:8056829. |
(2) the amount of total activatable enzyme synergistically increased (10-fold) under the influence of il-1 alpha and egf, whereas il-1 alpha alone showed a 4-fold enhancement compared to control or egf-incubated explants. |
1994-09-13 |
2023-08-12 |
rabbit |
| E van der Zee, V Everts, K Hoeben, W Beertse. Immunolocalisation of collagenase in rabbit periosteal tissue explants and extraction of the enzyme. The effect of the cytokines IL-1 alpha and EGF. Journal of cell science. vol 107 ( Pt 4). 1994-09-13. PMID:8056829. |
(3) the latent fraction of the enzyme was synergistically increased (up to 100-fold or more) in periostea cultured in the presence of il-1 alpha + egf (21.17 mu/explant versus 0.05 mu/explant in controls). |
1994-09-13 |
2023-08-12 |
rabbit |
| M Yanagisawa, H Imai, Y Fukushima, T Yasuda, A B Miura, Y Nakamot. Effects of tumour necrosis factor alpha and interleukin 1 beta on the proliferation of cultured glomerular epithelial cells. Virchows Archiv : an international journal of pathology. vol 424. issue 6. 1994-09-09. PMID:8055151. |
the effect of tnf alpha depended mainly on its interaction with epidermal growth factor (egf). |
1994-09-09 |
2023-08-12 |
human |
| M Yanagisawa, H Imai, Y Fukushima, T Yasuda, A B Miura, Y Nakamot. Effects of tumour necrosis factor alpha and interleukin 1 beta on the proliferation of cultured glomerular epithelial cells. Virchows Archiv : an international journal of pathology. vol 424. issue 6. 1994-09-09. PMID:8055151. |
this study showed that activated monocytes secrete growth factors for gec in vitro, and that interaction between both tnf alpha and il-1 beta and between tnf alpha and egf can modulate gec proliferation. |
1994-09-09 |
2023-08-12 |
human |
| P Limonta, R M Moretti, D Dondi, M M Marelli, M Mott. Androgen-dependent prostatic tumors: biosynthesis and possible actions of LHRH. The Journal of steroid biochemistry and molecular biology. vol 49. issue 4-6. 1994-08-26. PMID:8043499. |
t positively regulates this egf/tgf alpha system by increasing the concentration of egf binding sites. |
1994-08-26 |
2023-08-12 |
human |
| H Slama, D Vaillancourt, A K Gof. Control of in vitro prostaglandin F2 alpha and E2 synthesis by caruncular and allantochorionic tissues from cows that calved normally and those with retained fetal membranes. Domestic animal endocrinology. vol 11. issue 2. 1994-08-26. PMID:8045099. |
addition of oxytocin (100 microu/ml), platelet activating factor (paf, 100 ng/ml) and epidermal growth factor (egf, 100 ng/ml) had no effect on secretion of pgf2 alpha from the caruncle, but oxytocin and paf did stimulate pge2. |
1994-08-26 |
2023-08-12 |
Not clear |
| M A Steller, S C Mok, J Yeh, V Fulop, D J Anderson, R S Berkowit. Effects of cytokines on epidermal growth factor receptor expression by malignant trophoblast cells in vitro. The Journal of reproductive medicine. vol 39. issue 3. 1994-08-16. PMID:8035376. |
jeg-3 human cca cells were incubated with varying concentrations of interleukin 1-alpha (il-1 alpha), interleukin 1-beta (il-1 beta), interleukin 2, gamma-interferon, granulocyte-macrophage colony stimulating factor and tumor necrosis factor-alpha (tnf), and the expression of egf receptor was measured by radioimmunoassay using a murine monoclonal antibody with specificity for the egf receptor. |
1994-08-16 |
2023-08-12 |
human |
| N Chegini, Y Zhao, F W McLea. Expression of messenger ribonucleic acid and presence of immunoreactive proteins for epidermal growth factor (EGF), transforming growth factor alpha (TGF alpha) and EGF/TGF alpha receptors and 125I-EGF binding sites in human fallopian tube. Biology of reproduction. vol 50. issue 5. 1994-08-05. PMID:8025160. |
expression of messenger ribonucleic acid and presence of immunoreactive proteins for epidermal growth factor (egf), transforming growth factor alpha (tgf alpha) and egf/tgf alpha receptors and 125i-egf binding sites in human fallopian tube. |
1994-08-05 |
2023-08-12 |
human |
| N Chegini, Y Zhao, F W McLea. Expression of messenger ribonucleic acid and presence of immunoreactive proteins for epidermal growth factor (EGF), transforming growth factor alpha (TGF alpha) and EGF/TGF alpha receptors and 125I-EGF binding sites in human fallopian tube. Biology of reproduction. vol 50. issue 5. 1994-08-05. PMID:8025160. |
reverse transcription polymerase chain reaction (rt-pcr) revealed that the fallopian tubes express epidermal growth factor (egf), transforming growth factor (tgf alpha), and egf receptor (egf-r) mrna. |
1994-08-05 |
2023-08-12 |
human |
| N Chegini, Y Zhao, F W McLea. Expression of messenger ribonucleic acid and presence of immunoreactive proteins for epidermal growth factor (EGF), transforming growth factor alpha (TGF alpha) and EGF/TGF alpha receptors and 125I-EGF binding sites in human fallopian tube. Biology of reproduction. vol 50. issue 5. 1994-08-05. PMID:8025160. |
the intensity of immunoreactive tgf alpha with these antibodies was similar to that seen with egf. |
1994-08-05 |
2023-08-12 |
human |
| H Vanderstichele, B Delaey, J de Winter, F de Jong, L Rombauts, G Verhoeven, C Dello, A van de Voorde, T Brier. Secretion of steroids, growth factors, and cytokines by immortalized mouse granulosa cell lines. Biology of reproduction. vol 50. issue 5. 1994-08-05. PMID:8025176. |
both epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) induced the secretion of progesterone in grm02 cells, while no effect was obtained with tgf beta. |
1994-08-05 |
2023-08-12 |
mouse |
| N Normanno, F Ciardiello, R Brandt, D S Salomo. Epidermal growth factor-related peptides in the pathogenesis of human breast cancer. Breast cancer research and treatment. vol 29. issue 1. 1994-07-29. PMID:7912564. |
a number of different epidermal growth factor (egf)-related peptides such as egf, transforming growth factor alpha (tgf alpha), amphiregulin (ar), heregulin (hrg), and cripto-1 (cr-1), are coexpressed to varying degrees in both normal and malignant mammary epithelial cells. |
1994-07-29 |
2023-08-12 |
human |
| S Ohno, K Mizuno, Y Adachi, A Hata, Y Akita, K Akimoto, S Osada, S Hirai, K Suzuk. Activation of novel protein kinases C delta and C epsilon upon mitogenic stimulation of quiescent rat 3Y1 fibroblasts. The Journal of biological chemistry. vol 269. issue 26. 1994-07-29. PMID:8021256. |
the phosphorylation levels of endogenous pkc members determined by in vivo metabolic labeling experiments revealed increased phosphorylation of both npkc delta and npkc epsilon, but only a slight increase for cpkc alpha in response to serum or egf. |
1994-07-29 |
2023-08-12 |
rat |
| S Ohno, K Mizuno, Y Adachi, A Hata, Y Akita, K Akimoto, S Osada, S Hirai, K Suzuk. Activation of novel protein kinases C delta and C epsilon upon mitogenic stimulation of quiescent rat 3Y1 fibroblasts. The Journal of biological chemistry. vol 269. issue 26. 1994-07-29. PMID:8021256. |
in contrast to these nonphysiological stimuli, serum (or egf) stimulation of 3y1 cells that overexpress the respective pkc members revealed a clear difference between cpkc and npkc, in that overexpression of npkc delta or npkc epsilon resulted in a large increase in tpa- or serum-responsive element activation, whereas the overexpression of cpkc alpha increased activation only very slightly. |
1994-07-29 |
2023-08-12 |
rat |