| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Romano, E R Kraus, C R Boland, R J Coffe. Comparison between transforming growth factor alpha and epidermal growth factor in the protection of rat gastric mucosa against drug-induced injury. The Italian journal of gastroenterology. vol 26. issue 5. 1994-11-21. PMID:7522648. |
parenteral administration of tgf alpha and egf prevented 100% ethanol-induced mucosal injury to a similar extent. |
1994-11-21 |
2023-08-12 |
human |
| M Romano, E R Kraus, C R Boland, R J Coffe. Comparison between transforming growth factor alpha and epidermal growth factor in the protection of rat gastric mucosa against drug-induced injury. The Italian journal of gastroenterology. vol 26. issue 5. 1994-11-21. PMID:7522648. |
tgf alpha and egf did not afford significant protection of the gastric mucosa when administered orogastrically. |
1994-11-21 |
2023-08-12 |
human |
| M Romano, E R Kraus, C R Boland, R J Coffe. Comparison between transforming growth factor alpha and epidermal growth factor in the protection of rat gastric mucosa against drug-induced injury. The Italian journal of gastroenterology. vol 26. issue 5. 1994-11-21. PMID:7522648. |
we also evaluated the effect of tgf alpha and egf on insoluble (adherent) gastric mucin and found that both compounds dose-dependently stimulated adherent mucin in a time frame consistent with their protective effect. |
1994-11-21 |
2023-08-12 |
human |
| M Romano, E R Kraus, C R Boland, R J Coffe. Comparison between transforming growth factor alpha and epidermal growth factor in the protection of rat gastric mucosa against drug-induced injury. The Italian journal of gastroenterology. vol 26. issue 5. 1994-11-21. PMID:7522648. |
in conclusion, tgf alpha and egf are equally effective in preventing drug-induced injury to the rat gastric mucosa. |
1994-11-21 |
2023-08-12 |
human |
| R D Christen, S Isonishi, J A Jones, A P Jekunen, D K Hom, R Kröning, D P Gately, F B Thiebaut, G Los, S B Howel. Signaling and drug sensitivity. Cancer metastasis reviews. vol 13. issue 2. 1994-11-17. PMID:7923549. |
these signaling events include pathways activated by the epidermal growth factor (egf) receptor, tumor necrosis factor alpha (tnf alpha) receptor, bombesin receptor, protein kinase a (pka), and protein kinase c (pkc). |
1994-11-17 |
2023-08-12 |
human |
| T Moriai, M S Kobrin, C Hope, L Speck, M Kor. A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 21. 1994-11-10. PMID:7937865. |
epidermal growth factor (egf) and type alpha transforming growth factor (tgf-alpha) bind to a specific region in subdomain iii of the extracellular portion of the egf receptor (egfr). |
1994-11-10 |
2023-08-12 |
human |
| Y Saito, J R Vandenheede, P Cohe. The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells. The Biochemical journal. vol 303 ( Pt 1). 1994-11-09. PMID:7945252. |
egf stimulation of a431 cells inhibited gsk3 alpha and gsk3 beta to a similar extent, and inhibition was accompanied by phosphorylation of the tryptic peptides containing the serine residues phosphorylated in vitro by p70 s6 kinase or map kinase-activated protein (mapkap) kinase-1 beta (also termed rsk-2). |
1994-11-09 |
2023-08-12 |
Not clear |
| M J Peddie, O M Onagbesan, J William. Chicken granulosa cell proliferation and progesterone production in culture: effects of EGF and theca secretions. General and comparative endocrinology. vol 94. issue 3. 1994-11-08. PMID:7926642. |
paracrine/autocrine factors like epidermal growth factor (egf) and transforming growth factor (tgf alpha) produced in the mammalian ovary modulate ovarian functions such as cell proliferation, differentiation, and steroidogenesis. |
1994-11-08 |
2023-08-12 |
chicken |
| E K Asem, R P Nover. Stimulation of fibronectin production and deposition by chicken granulosa cells in vitro by epidermal growth factor and transforming growth factor alpha. Journal of reproduction and fertility. vol 101. issue 2. 1994-11-03. PMID:7932372. |
experiments were conducted in vitro to examine the effect of epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha) on the production of fibronectin (deposited, secreted into medium and cell-associated) by hen granulosa cells isolated from the largest (f1; about 35 mm in diameter, mature) and third largest (f3; 15-20 mm in diameter) preovulatory follicles, as well as from a pool of immature small yellow follicles (6-8 mm in diameter). |
1994-11-03 |
2023-08-12 |
chicken |
| A G Stewart, G Grigoriadis, T Harri. Mitogenic actions of endothelin-1 and epidermal growth factor in cultured airway smooth muscle. Clinical and experimental pharmacology & physiology. vol 21. issue 4. 1994-10-27. PMID:7923893. |
it is suggested that stimulants at the egf receptor (egf and transforming growth factor alpha) may play a role in the airway smooth muscle hyperplasia in asthma. |
1994-10-27 |
2023-08-12 |
Not clear |
| J P Scurry, K A Hamand, S B Astley, R E Leake, M Well. Immunoreactivity of antibodies to epidermal growth factor, transforming growth factors alpha and beta, and epidermal growth factor receptor in the premenopausal ovary. Pathology. vol 26. issue 2. 1994-10-20. PMID:8090583. |
antibodies to epidermal growth factor (egf), transforming growth factors alpha and beta (tgf alpha and beta) and epidermal growth factor receptor (egfr) were applied to paraffin sections of 16 cases of formalin-fixed normal or benignly abnormal ovarian tissue. |
1994-10-20 |
2023-08-12 |
human |
| H Kurach. [Growth factors in gynecology]. Nihon Sanka Fujinka Gakkai zasshi. vol 46. issue 8. 1994-10-18. PMID:8089608. |
among many kinds of growth factors, epidermal growth factor (egf) and transforming growth factor (tgf)alpha are mentioned; both of these are called as egf family because these share a common receptor (egf receptor) and show similar biological activities. |
1994-10-18 |
2023-08-12 |
mouse |
| H Kurach. [Growth factors in gynecology]. Nihon Sanka Fujinka Gakkai zasshi. vol 46. issue 8. 1994-10-18. PMID:8089608. |
we studied the expression and role of egf and tgf alpha in human fallopian tube. |
1994-10-18 |
2023-08-12 |
mouse |
| H Kurach. [Growth factors in gynecology]. Nihon Sanka Fujinka Gakkai zasshi. vol 46. issue 8. 1994-10-18. PMID:8089608. |
immunohistochemical and rt-pcr studies revealed the menstrual stages specific synthesis and expression of egf and tgf alpha in tubal epithelial cells. |
1994-10-18 |
2023-08-12 |
mouse |
| H Kurach. [Growth factors in gynecology]. Nihon Sanka Fujinka Gakkai zasshi. vol 46. issue 8. 1994-10-18. PMID:8089608. |
these facts suggest that egf and egf alpha expressed in human epithelial cells promote embryo development in a paracrine manner. |
1994-10-18 |
2023-08-12 |
mouse |
| P W Sylvester, H P Birkenfeld, H L Hosick, K P Brisk. Fatty acid modulation of epidermal growth factor-induced mouse mammary epithelial cell proliferation in vitro. Experimental cell research. vol 214. issue 1. 1994-10-12. PMID:8082717. |
since egf can induce both pkc activation and cell proliferation, and because pkc activation requires membrane-derived phospholipids and diacylglycerol, these data suggest that specific fatty acid modulation of mammary epithelial cell mitogenesis is mediated through alterations in pkc alpha activation. |
1994-10-12 |
2023-08-12 |
mouse |
| Y J Ma, K Berg-von der Emde, M Moholt-Siebert, D F Hill, S R Ojed. Region-specific regulation of transforming growth factor alpha (TGF alpha) gene expression in astrocytes of the neuroendocrine brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 9. 1994-10-12. PMID:8083760. |
treatment with either tgf alpha or its structural homolog, epidermal growth factor (egf), increased tgf alpha mrna levels within 8 hr of exposure; the phorbol ester 12-o-tetradecanoyl-phorbol-13-acetate (tpa) was similarly effective. |
1994-10-12 |
2023-08-12 |
Not clear |
| Y J Ma, K Berg-von der Emde, M Moholt-Siebert, D F Hill, S R Ojed. Region-specific regulation of transforming growth factor alpha (TGF alpha) gene expression in astrocytes of the neuroendocrine brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 9. 1994-10-12. PMID:8083760. |
in contrast to hypothalamic astrocytes, cerebellar astrocytes did not respond to either tgf alpha or egf with changes in tgf alpha mrna abundance. |
1994-10-12 |
2023-08-12 |
Not clear |
| N Ni, J D Yage. The co-mitogenic effects of various estrogens for TGF-alpha-induced DNA synthesis in cultured female rat hepatocytes. Cancer letters. vol 84. issue 2. 1994-10-04. PMID:8076369. |
the endogenous estrogen 17 beta-estradiol (e2) also exhibits co-mitogenic activity, enhancing the fraction of hepatocytes undergoing dna synthesis induced by both egf and transforming growth factor alpha (tgf-alpha) (ni, n. and yager, j.d. |
1994-10-04 |
2023-08-12 |
rat |
| H Cao, Z M Lei, C V Ra. Transcriptional and posttranscriptional mechanisms in epidermal growth factor regulation of human chorionic gonadotropin (hCG) subunits and hCG receptor gene expression in human choriocarcinoma cells. Endocrinology. vol 135. issue 3. 1994-09-26. PMID:8070393. |
egf treatment resulted in a dose- and time-dependent increase in steady state levels of hcg alpha and hcg beta mrnas. |
1994-09-26 |
2023-08-12 |
human |