| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L M Neri, A M Billi, L Manzoli, S Rubbini, R S Gilmour, L Cocco, A M Martell. Selective nuclear translocation of protein kinase C alpha in Swiss 3T3 cells treated with IGF-I, PDGF and EGF. FEBS letters. vol 347. issue 1. 1994-07-28. PMID:8013664. |
selective nuclear translocation of protein kinase c alpha in swiss 3t3 cells treated with igf-i, pdgf and egf. |
1994-07-28 |
2023-08-12 |
Not clear |
| L M Neri, A M Billi, L Manzoli, S Rubbini, R S Gilmour, L Cocco, A M Martell. Selective nuclear translocation of protein kinase C alpha in Swiss 3T3 cells treated with IGF-I, PDGF and EGF. FEBS letters. vol 347. issue 1. 1994-07-28. PMID:8013664. |
in isolated nuclei from gf-exposed cells only the alpha isozyme was detected: immunostaining was very intense after igf-i treatment and clearly observable after pdgf and egf stimulation. |
1994-07-28 |
2023-08-12 |
Not clear |
| T G Kennedy, K D Brown, T J Vaugha. Expression of the genes for the epidermal growth factor receptor and its ligands in porcine oviduct and endometrium. Biology of reproduction. vol 50. issue 4. 1994-07-05. PMID:7515285. |
we have used the reverse transcription-polymerase chain reaction (rt-pcr) to determine whether transcripts for the epidermal growth factor (egf) receptor and its four known ligands--egf, transforming growth factor alpha (tgf alpha), amphiregulin (ar), and heparin-binding egf (hb-egf)--are expressed in porcine oviduct and endometrium. |
1994-07-05 |
2023-08-12 |
Not clear |
| C Dean, H Modjtahedi, S Eccles, G Box, J Style. Immunotherapy with antibodies to the EGF receptor. International journal of cancer. Supplement = Journal international du cancer. Supplement. vol 8. 1994-06-27. PMID:8194887. |
a series of rat monoclonal antibodies (mabs) has been generated against the extracellular domain of the receptor for egf which block the binding of egf and tgf alpha to the receptor and inhibit the growth in vitro of a range of carcinoma cell lines that over-express the receptor for egf. |
1994-06-27 |
2023-08-12 |
rat |
| C F Qi, D S Liscia, N Normanno, G Merlo, G R Johnson, W J Gullick, F Ciardiello, T Saeki, R Brandt, N Ki. Expression of transforming growth factor alpha, amphiregulin and cripto-1 in human breast carcinomas. British journal of cancer. vol 69. issue 5. 1994-06-15. PMID:8180021. |
the expression of three epidermal growth factor (egf)-related peptides, transforming growth factor alpha (tgf-alpha), amphiregulin (ar) and cripto-1 (cr-1), was examined by immunocytochemistry (icc) in 68 primary infiltrating ductal (idcs) and infiltrating lobular breast carcinomas (ilcs), and in 23 adjacent non-involved human mammary tissue samples. |
1994-06-15 |
2023-08-12 |
human |
| J Che. [Gene expression of TGF alpha, TGF beta 1 and C-erbB2 oncogene in human pancreatic carcinoma cell lines]. Zhonghua zhong liu za zhi [Chinese journal of oncology]. vol 15. issue 4. 1994-06-09. PMID:7909745. |
in this study, gene expression of tgf alpha (a ligand of egf receptor), tgf beta 1 and c-erbb2 oncogene were studied. |
1994-06-09 |
2023-08-12 |
human |
| N Davies, P Kapur, J Gillespie, P J Guillou, G J Posto. Transforming growth factor alpha is trophic to pancreatic cancer in vivo. Gut. vol 34. issue 8. 1994-06-07. PMID:8174961. |
pancreatic cancer cell lines overexpress epidermal growth factor (egf) receptors and also have the capacity to produce transforming growth factor alpha (tgf alpha), the alternate agonist of the egf receptor. |
1994-06-07 |
2023-08-12 |
Not clear |
| N Davies, P Kapur, J Gillespie, P J Guillou, G J Posto. Transforming growth factor alpha is trophic to pancreatic cancer in vivo. Gut. vol 34. issue 8. 1994-06-07. PMID:8174961. |
from week four onwards both egf and tgf alpha significantly stimulated tumour growth. |
1994-06-07 |
2023-08-12 |
Not clear |
| N Davies, P Kapur, J Gillespie, P J Guillou, G J Posto. Transforming growth factor alpha is trophic to pancreatic cancer in vivo. Gut. vol 34. issue 8. 1994-06-07. PMID:8174961. |
although tumour weights were not significantly different, tumour dna content had nearly doubled after exposure to both egf and tgf alpha. |
1994-06-07 |
2023-08-12 |
Not clear |
| N Davies, P Kapur, J Gillespie, P J Guillou, G J Posto. Transforming growth factor alpha is trophic to pancreatic cancer in vivo. Gut. vol 34. issue 8. 1994-06-07. PMID:8174961. |
it is concluded that like egf, tgf alpha can stimulate pancreatic cancer growth in vivo, and this may in part explain the aggressive nature of these cancers in clinical practice. |
1994-06-07 |
2023-08-12 |
Not clear |
| B L Tepperman, B D Sope. Effect of epidermal growth factor, transforming growth factor alpha and nerve growth factor on gastric mucosal integrity and microcirculation in the rat. Regulatory peptides. vol 50. issue 1. 1994-05-13. PMID:8159804. |
in the present study we have compared the effects of the peptide growth factors epidermal growth factor (egf), transforming growth factor alpha (tgf alpha) and nerve growth factor (ngf) on gastric mucosal integrity and mucosal blood flow in the rat. |
1994-05-13 |
2023-08-12 |
rat |
| B L Tepperman, B D Sope. Effect of epidermal growth factor, transforming growth factor alpha and nerve growth factor on gastric mucosal integrity and microcirculation in the rat. Regulatory peptides. vol 50. issue 1. 1994-05-13. PMID:8159804. |
gastric mucosal blood flow as assessed by laser doppler flowmetry (ldf) was increased in a dose-dependent and equipotent manner by egf and tgf alpha administered either by the i.v. |
1994-05-13 |
2023-08-12 |
rat |
| B L Tepperman, B D Sope. Effect of epidermal growth factor, transforming growth factor alpha and nerve growth factor on gastric mucosal integrity and microcirculation in the rat. Regulatory peptides. vol 50. issue 1. 1994-05-13. PMID:8159804. |
ldf changes were greater when egf or tgf alpha were delivered via the i.a. |
1994-05-13 |
2023-08-12 |
rat |
| B L Tepperman, B D Sope. Effect of epidermal growth factor, transforming growth factor alpha and nerve growth factor on gastric mucosal integrity and microcirculation in the rat. Regulatory peptides. vol 50. issue 1. 1994-05-13. PMID:8159804. |
abolished the increase in ldf in response to egf or tgf alpha but did not affect the ability of these growth factors to reduce etoh-mediated damage. |
1994-05-13 |
2023-08-12 |
rat |
| b' R K Rao, K Lam, A F Philipps, C Williams, M Lake, O Koldovsk\\xc3\\xb. Presence of multiple forms of peptidase inhibitors in rat milk. Journal of pediatric gastroenterology and nutrition. vol 17. issue 4. 1994-05-04. PMID:8145098.' |
peptides such as somatostatin (ss14), epidermal growth factor (egf), transforming growth factor-alpha (tgf alpha), and insulin-like growth factors (igf-i and igf-ii) are present in breast milk from various species, and their significance in the developing gastrointestinal tract has been suggested. |
1994-05-04 |
2023-08-12 |
rat |
| D Brouty-Boyé, V Magnie. Myofibroblast and concurrent ED-B fibronectin phenotype in human stromal cells cultured from non-malignant and malignant breast tissue. European journal of cancer (Oxford, England : 1990). vol 30A. issue 1. 1994-05-03. PMID:8142168. |
epidermal growth factor (egf), fibroblast growth factor b (fgfb), transforming growth factor alpha (tgf alpha) and platelet-derived growth factor (pdgf) showed consistent mitogenic effects. |
1994-05-03 |
2023-08-12 |
human |
| H Modjtahedi, S Eccles, J Sandle, G Box, J Titley, C Dea. Differentiation or immune destruction: two pathways for therapy of squamous cell carcinomas with antibodies to the epidermal growth factor receptor. Cancer research. vol 54. issue 7. 1994-04-28. PMID:8137284. |
we conclude that antibodies which block the binding of egf and transforming growth factor alpha to the egfr can inhibit the growth of egfr-overexpressing tumors by directing terminal differentiation and that a further therapeutic benefit may be obtained via immunological mechanisms with rat igg2b mabs such as icr62. |
1994-04-28 |
2023-08-12 |
mouse |
| U Kellner, B Wagner, U Otto, K D Voigt, M Dietel, C Knabb. [Androgen regulation of secreted growth factors in prostate carcinoma cell and tumor lines]. Verhandlungen der Deutschen Gesellschaft fur Pathologie. vol 77. 1994-04-25. PMID:7511269. |
lncap and du 145 cells express high affinity egf-receptors and show an increased growth rate under treatment with egf, tgf alpha and fgf. |
1994-04-25 |
2023-08-12 |
mouse |
| K Wickström, K Madse. The effect of transforming growth factor-alpha (TGF alpha) on rabbit and primate lens epithelial cells in vitro. Current eye research. vol 12. issue 12. 1994-04-25. PMID:8137635. |
in this study, the effect of tgf alpha on lens epithelial cells (lec) from rabbit and monkey was investigated and compared to fgf and egf. |
1994-04-25 |
2023-08-12 |
rabbit |
| Z Zhong, Z Wen, J E Darnel. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science (New York, N.Y.). vol 264. issue 5155. 1994-04-25. PMID:8140422. |
it is likely that this phosphoprotein forms homodimers as well as heterodimers with the first described member of the stat family, stat91 (renamed stat1 alpha), which is activated by the ifns and egf. |
1994-04-25 |
2023-08-12 |
Not clear |