| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Fujii, N Dousaka-Nakajima, S Imamur. Epidermal growth factor enhancement of HSC-1 human cutaneous squamous carcinoma cell adhesion and migration on type I collagen involves selective up-regulation of alpha 2 beta 1 integrin expression. Experimental cell research. vol 216. issue 1. 1995-02-09. PMID:7529189. |
elisa and immunoprecipitation studies showed that egf up-regulated the expression of alpha 2 beta 1 integrin collagen receptor in a time- and dose-dependent manner by stimulating biosynthesis of alpha 2 subunit, but did not up-regulate those of the alpha 3 beta 1, alpha 5 beta 1, or alpha v beta 3 integrins. |
1995-02-09 |
2023-08-12 |
human |
| K Fujii, N Dousaka-Nakajima, S Imamur. Epidermal growth factor enhancement of HSC-1 human cutaneous squamous carcinoma cell adhesion and migration on type I collagen involves selective up-regulation of alpha 2 beta 1 integrin expression. Experimental cell research. vol 216. issue 1. 1995-02-09. PMID:7529189. |
these results suggest that egf preferentially enhances hsc-1 cell interaction with type i collagen, leading to the enhanced cellular migratory activity on the substratum, as a result of selective up-regulation of alpha 2 beta 1 integrin expression. |
1995-02-09 |
2023-08-12 |
human |
| M B Ortiz, M Goin, M B Gomez de Alzaga, S Hammarstrom, L Jimenez de Asu. Mevalonate dependency of the early cell cycle mitogenic response to epidermal growth factor and prostaglandin F2 alpha in Swiss mouse 3T3 cells. Journal of cellular physiology. vol 162. issue 1. 1995-02-03. PMID:7814446. |
lovastatin (lov), a hydroxy-methylglutaryl-coenzyme a (hmgcoa) reductase competitive inhibitor, blocks epidermal growth factor (egf)- or prostaglandin f2 alpha (pgf2 alpha)-induced mitogenesis in confluent resting swiss 3t3 cells. |
1995-02-03 |
2023-08-12 |
mouse |
| M B Ortiz, M Goin, M B Gomez de Alzaga, S Hammarstrom, L Jimenez de Asu. Mevalonate dependency of the early cell cycle mitogenic response to epidermal growth factor and prostaglandin F2 alpha in Swiss mouse 3T3 cells. Journal of cellular physiology. vol 162. issue 1. 1995-02-03. PMID:7814446. |
these findings strongly suggest that either egf or pgf2 alpha stimulations generate early cell cycle signals which induce mevalonate formation, n' glycoprotein synthesis, and proliferation. |
1995-02-03 |
2023-08-12 |
mouse |
| A Lövqvist, A Lindström, J Carlsso. Binding, internalization and excretion of TGF alpha-dextran associated radioactivity in cultured human glioma cells. Cancer biotherapy. vol 8. issue 4. 1995-02-01. PMID:7528599. |
furthermore, by comparison with previously published results, it was seen that the radioactivity delivered through the tgf alpha part of tgf alpha-dextran was retained for a shorter period of time by the cells than when delivered by egf in egf-dextran conjugates. |
1995-02-01 |
2023-08-12 |
human |
| J McAndrew, D G Fernig, P S Rudland, J A Smit. Secretion of transforming growth factor alpha and expression of its receptor in human mammary cell lines. Growth factors (Chur, Switzerland). vol 10. issue 4. 1995-01-30. PMID:7803044. |
the secretion of transforming growth factor alpha (tgf alpha) and the expression of cell-surface receptors for epidermal growth factor (egf) were measured in a series of human mammary cell lines. |
1995-01-30 |
2023-08-12 |
human |
| M Westphal, D Stavrou, H Nausch, J M Valdueza, H D Herrman. Human neurocytoma cells in culture show characteristics of astroglial differentiation. Journal of neuroscience research. vol 38. issue 6. 1995-01-30. PMID:7807585. |
epidermal growth factor (egf) was mitogenic for the cultured cells but not platelet derived growth factor alpha (pdgf aa) or nerve growth factor (ngf). |
1995-01-30 |
2023-08-12 |
human |
| J A Vega, E Vazquez, F J Naves, B Calzada, M E del Valle, J J Repres. Expression of epidermal growth factor receptor (EGFr) immunoreactivity in human cutaneous nerves and sensory corpuscles. The Anatomical record. vol 240. issue 1. 1995-01-30. PMID:7810909. |
the epidermal growth factor receptor (egfr) binds both epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha), which are currently considered among putative growth factors playing a role in the nervous system. |
1995-01-30 |
2023-08-12 |
human |
| N H James, R A Robert. The peroxisome proliferator class of non-genotoxic hepatocarcinogens synergize with epidermal growth factor to promote clonal expansion of initiated rat hepatocytes. Carcinogenesis. vol 15. issue 12. 1995-01-26. PMID:8001222. |
taken together, these data suggest that some pps act as hepatocarcinogens by synergizing with egf and/or tgf alpha to promote the clonal expansion of spontaneously initiated hepatocytes. |
1995-01-26 |
2023-08-12 |
rat |
| O M Onagbesan, W Gullick, I Woolveridge, M J Peddi. Immunohistochemical localization of epidermal growth factor receptors, epidermal-growth-factor-like and transforming-growth-factor-alpha-like peptides in chicken ovarian follicles. Journal of reproduction and fertility. vol 102. issue 1. 1995-01-24. PMID:7799307. |
the purpose of this study was to determine the presence of epidermal growth factor receptor and its potential ligands epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha) in the tissues of the maturing follicles in the ovary of laying isa-brown hens using peptide-specific immunohistochemical methods. |
1995-01-24 |
2023-08-12 |
chicken |
| A Minden, A Lin, M McMahon, C Lange-Carter, B Dérijard, R J Davis, G L Johnson, M Kari. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science (New York, N.Y.). vol 266. issue 5191. 1995-01-10. PMID:7992057. |
activation of jnk by epidermal growth factor (egf) or nerve growth factor (ngf) was dependent on h-ras activation, whereas jnk activation by tumor necrosis factor alpha (tnf-alpha) was ras-independent. |
1995-01-10 |
2023-08-12 |
Not clear |
| E J Lewintre, M Orava, R Vihk. Regulation of 17 beta-hydroxysteroid dehydrogenase type 1 by epidermal growth factor and transforming growth factor-alpha in choriocarcinoma cells. Endocrinology. vol 135. issue 6. 1995-01-06. PMID:7988452. |
in this study, we investigated the roles of epidermal growth factor (egf) and tumor growth factor-alpha (tgf alpha) in the regulation of 17hsd type 1 gene expression and catalytic activity in cultured jar, jeg-3, and bewo choriocarcinoma cells. |
1995-01-06 |
2023-08-12 |
human |
| E J Lewintre, M Orava, R Vihk. Regulation of 17 beta-hydroxysteroid dehydrogenase type 1 by epidermal growth factor and transforming growth factor-alpha in choriocarcinoma cells. Endocrinology. vol 135. issue 6. 1995-01-06. PMID:7988452. |
egf and tgf alpha increased 17hsd type 1 protein concentrations in jar and jeg-3 cells, as measured by time-resolved immunofluorometric assay, and 17hsd catalytic activity, as determined by production of estradiol from estrone. |
1995-01-06 |
2023-08-12 |
human |
| E J Lewintre, M Orava, R Vihk. Regulation of 17 beta-hydroxysteroid dehydrogenase type 1 by epidermal growth factor and transforming growth factor-alpha in choriocarcinoma cells. Endocrinology. vol 135. issue 6. 1995-01-06. PMID:7988452. |
these results suggest that egf and/or tgf alpha may play an important role in 17hsd type 1 regulation and, consequently, in estrogen production in the human placenta. |
1995-01-06 |
2023-08-12 |
human |
| N S Falette, N Artagaveytia, M C Rostan, E Garin, J Y Bobin, S Sae. Analysis of epidermal growth factor receptor mRNA expression by polymerase chain reaction assay in 94 human breast adenocarcinoma tumors. Breast cancer research and treatment. vol 30. issue 3. 1995-01-05. PMID:7981445. |
egf and tgf alpha (egf-like peptide) are produced in variable amounts and both bind to the egf receptor (egf-r). |
1995-01-05 |
2023-08-12 |
human |
| G Vassaux, R Négrel, G Ailhaud, D Gaillar. Proliferation and differentiation of rat adipose precursor cells in chemically defined medium: differential action of anti-adipogenic agents. Journal of cellular physiology. vol 161. issue 2. 1994-12-28. PMID:7962109. |
epidermal growth factor (egf) and prostaglandin f2 alpha (pgf2 alpha) do not show any effect on cell proliferation at concentrations which exert a maximal inhibitory action on differentiation. |
1994-12-28 |
2023-08-12 |
rat |
| G Vassaux, R Négrel, G Ailhaud, D Gaillar. Proliferation and differentiation of rat adipose precursor cells in chemically defined medium: differential action of anti-adipogenic agents. Journal of cellular physiology. vol 161. issue 2. 1994-12-28. PMID:7962109. |
upon removal of egf from the culture medium, complete resumption of differentiation occurs, whereas upon removal of pgf2 alpha or smgk, complete resumption only takes place when differentiation is triggered by cpgi2. |
1994-12-28 |
2023-08-12 |
rat |
| G Grupcev, C Wallin, S Emås, E Theodorsson, P M Hellströ. Transforming growth factor-alpha and epidermal growth factor inhibit gastric acid secretion and stimulate release of somatostatin and neurotensin in the conscious rat. Regulatory peptides. vol 52. issue 2. 1994-12-28. PMID:7972934. |
the study compared inhibitory actions of transforming growth factor-alpha (tgf alpha) and epidermal growth factor (egf) on gastric acid secretion and effects of these peptides on release of gut peptides considered important for acid inhibitory and gastrointestinal protective mechanisms. |
1994-12-28 |
2023-08-12 |
rat |
| G Grupcev, C Wallin, S Emås, E Theodorsson, P M Hellströ. Transforming growth factor-alpha and epidermal growth factor inhibit gastric acid secretion and stimulate release of somatostatin and neurotensin in the conscious rat. Regulatory peptides. vol 52. issue 2. 1994-12-28. PMID:7972934. |
tgf alpha and egf did not affect basal acid secretion, but inhibited pentagastrin-stimulated acid secretion in a dose-dependent manner from 0.10 to 1.7 nmol kg-1 h-1 i.v. |
1994-12-28 |
2023-08-12 |
rat |
| G Grupcev, C Wallin, S Emås, E Theodorsson, P M Hellströ. Transforming growth factor-alpha and epidermal growth factor inhibit gastric acid secretion and stimulate release of somatostatin and neurotensin in the conscious rat. Regulatory peptides. vol 52. issue 2. 1994-12-28. PMID:7972934. |
by maximally 72% for tgf alpha (p < 0.001) and 76% for egf (p < 0.001). |
1994-12-28 |
2023-08-12 |
rat |