| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Selena Singh, Suzanna Becker, Thomas Trappenberg, Abraham Nune. Granule cells perform frequency-dependent pattern separation in a computational model of the dentate gyrus. Hippocampus. 2023-11-11. PMID:37950569. |
we aim to study, in a computational model of the hippocampal dentate gyrus (dg), the network and cellular mechanisms governing this putative "u"-shaped ps relationship. |
2023-11-11 |
2023-11-20 |
Not clear |
| Yasunori Takahashi, Ryota Ojiro, Risako Yamashita, Saori Shimizu, Natsuno Maeda, Xinyu Zou, Qian Tang, Shunsuke Ozawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutan. Suppression of neurogranin expression by disruption of epigenetic DNA methylation in hippocampal mature granule cells after developmental exposure to neurotoxicants in rats. Toxicology letters. 2023-11-05. PMID:37926403. |
we previously performed comprehensive analyses of genes hypermethylated promoter regions and downregulated transcripts in the hippocampal dentate gyrus (dg) of rats upon weaning at postnatal day (pnd) 21 after developmental exposure to 6-propyl-2-thiouracil (ptu), valproic acid, and glycidol (gly), all of which are known to show irreversible effects on hippocampal neurogenesis in adulthood on pnd 77. |
2023-11-05 |
2023-11-08 |
rat |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
moreover, mh could not only significantly up-regulated the expressions of cfos, but also obviously increased the number of ki67 positive cells in hippocampal dentate gyrus (dg). |
2023-11-04 |
2023-11-08 |
mouse |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
in addition, pharmacological inhibition of camkii by using kn-93 (a camkii antagonist) blocked the mh's up-regulation of cfos and ki67 in hippocampal dg. |
2023-11-04 |
2023-11-08 |
mouse |
| Keqiang Gao, Mengxi Hu, Jiyang Li, Ziyi Li, Wei Xu, Zhiyu Qian, Fan Gao, Tengfei M. Drug-detecting bioelectronic nose based on odor cue memory combined with a brain computer interface. Biosensors & bioelectronics. vol 244. 2023-11-03. PMID:37922809. |
first, the rats were trained to generate positive memories of drug odors through food reward training, and multichannel microelectrodes were implanted into the dg region of the hippocampus for responsible memory retrieval, the spike signals of individual neurons and the local field potential signals of population neurons in the brain region were collected for pattern recognition and analysis. |
2023-11-03 |
2023-11-08 |
rat |
| Roya Homayouni, Kelsey L Canada, Samaah Saifullah, Da' Jonae Foster, Charlotte Thill, Naftali Raz, Ana M Daugherty, Noa Ofe. Age-related differences in hippocampal subfield volumes across the human lifespan: A meta-analysis. Hippocampus. 2023-10-26. PMID:37881160. |
it is comprised of cytoarchitectonically distinct subfields: dentate gyrus (dg), cornu ammonis sectors (ca) 1-4, and subiculum, each of which may be differentially susceptible to neurodevelopmental and neurodegenerative mechanisms. |
2023-10-26 |
2023-11-08 |
human |
| Shaoyi Fang, Zhibin Wu, Yali Guo, Wenjun Zhu, Chunmiao Wan, Naijun Yuan, Jianbei Chen, Wenzhi Hao, Xiaowei Mo, Xiaofang Guo, Lili Fan, Xiaojuan Li, Jiaxu Che. Roles of microglia in adult hippocampal neurogenesis in depression and their therapeutics. Frontiers in immunology. vol 14. 2023-10-26. PMID:37881439. |
adult hippocampal neurogenesis generates functional neurons from neural progenitor cells in the hippocampal dentate gyrus (dg) to complement and repair neurons and neural circuits, thus benefiting the treatment of depression. |
2023-10-26 |
2023-11-08 |
Not clear |
| Roya Homayouni, Ana M Daugherty, Qijing Yu, Naftali Raz, Noa Ofe. KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development. Brain structure & function. 2023-10-18. PMID:37853296. |
the hippocampus (hc) consists of cytoarchitectonically and functionally distinct subfields: dentate gyrus (dg), cornu ammonis (ca1-3), and subiculum. |
2023-10-18 |
2023-11-08 |
Not clear |
| Jean Philippe Djientcheu Tientcheu, Florence Tsofack Ngueguim, Racéline Kamkumo Gounoue, Michel Arnaud Mbock, Rodrigue Ngapout, Antoine Kavaye Kandeda, Théophile Dim. The extract of Sclerocarya birrea, Nauclea latifolia, and Piper longum mixture ameliorates diabetes-associated cognitive dysfunction. Metabolic brain disease. 2023-10-11. PMID:37821784. |
fructose/stz administration resulted in t2d, impaired short- and long-term memory, significantly increased oxidative/nitrative stress, pro-inflammatory cytokine levels, acetylcholinesterase activity (ache), hippocampal neuronal loss and degeneration in ca1 and ca3 subfields, and neuronal vacuolation in dg. |
2023-10-11 |
2023-10-15 |
rat |
| Yuk-Hoi Yiu, Christian Leibol. A theory of hippocampal theta correlations accounting for extrinsic and intrinsic sequences. eLife. vol 12. 2023-10-04. PMID:37792453. |
here, we propose a computational model of cornu ammonis 3 (ca3) and dentate gyrus (dg), where sensorimotor input drives the direction-dependent (extrinsic) theta sequences within ca3 reflecting the two-dimensional spatial topology, whereas the intrahippocampal ca3-dg projections concurrently produce intrinsic sequences that are independent of the specific running trajectory. |
2023-10-04 |
2023-10-07 |
Not clear |
| Carmela Belardo, Serena Boccella, Michela Perrone, Antimo Fusco, Andrea Maria Morace, Federica Ricciardi, Roozbe Bonsale, Ines ELBini-Dhouib, Francesca Guida, Livio Luongo, Giacinto Bagetta, Damiana Scuteri, Sabatino Maion. Scopolamine-Induced Memory Impairment in Mice: Effects of PEA-OXA on Memory Retrieval and Hippocampal LTP. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762702. |
consistently, electrophysiological analysis showed ltp recovery in the dg of the hippocampus, while the ach level and choa-t were normalized. |
2023-09-28 |
2023-10-07 |
mouse |
| Sahifeh Kazemi, Samaneh Safari, Somayeh Komaki, Seyed Asaad Karimi, Zoleikha Golipoor, Alireza Komak. The effects of carvacrol and p-cymene on Aβ CNS neuroscience & therapeutics. 2023-09-20. PMID:37727020. |
considering the beneficial effects of carvacrol (car) and p-cymene against ad, their effect was assessed on in vivo hippocampal ltp in the perforant pathway (pp)-dentate gyrus (dg) pathway in an aβ |
2023-09-20 |
2023-10-07 |
Not clear |
| Christos Panagiotis Lisgaras, Helen E Scharfma. Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by medial septum. Neurobiology of disease. 2023-09-15. PMID:37714307. |
because hippocampus and cortex exhibit altered excitability in ad models, we asked which areas dominate the activity during iis along the cortical-ca1-dentate gyrus (dg) dorso-ventral axis. |
2023-09-15 |
2023-10-07 |
mouse |
| Mingxie Ni, Meng Zheng, Bingran Chen, Xu Lu, Hui Zhao, Tao Zhu, Li Cheng, Han Han, Ting Ye, Huijun Liu, Ying Ye, Chao Huang, Xiaomei Yua. Microglial stimulation triggered by intranasal lipopolysaccharide administration produces antidepressant-like effect through ERK1/2-mediated BDNF synthesis in the hippocampus. Neuropharmacology. 2023-09-07. PMID:37678448. |
we recently reported that reversing the chronic stress-induced decline of microglia in the dentate gyrus (dg) of the hippocampus by intraperitoneal injection of a low dose of lipopolysaccharide (lps) ameliorated depression-like behavior in chronically stressed mice. |
2023-09-07 |
2023-10-07 |
mouse |
| Sumire Matsuura, Yuki Nishimoto, Akane Endo, Hirono Shiraki, Kanzo Suzuki, Eri Segi-Nishid. Hippocampal Inflammation and Gene Expression Changes in Peripheral Lipopolysaccharide Challenged Mice Showing Sickness and Anxiety-Like Behaviors. Biological & pharmaceutical bulletin. vol 46. issue 9. 2023-09-04. PMID:37661396. |
the aim of this study was to clarify temporal changes in the neuroinflammatory responses in the hippocampus and the response of dentate gyrus (dg) neurons using peripheral lipopolysaccharide (lps)-challenged mice. |
2023-09-04 |
2023-09-07 |
mouse |
| Satoshi Deyam. [Elucidation of the Mechanisms Underlying the Rapid Antidepressant Actions of Ketamine and Search for Possible Candidates for Novel Rapid-acting Antidepressants]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 143. issue 9. 2023-09-04. PMID:37661437. |
moreover, the intranasal administration of rve1 elicits rapid antidepressant-like effects through the release of bdnf and vegf in the mpfc and hippocampal dentate gyrus (dg), as well as mtorc1 activation in the mpfc, albeit not in the dg. |
2023-09-04 |
2023-09-07 |
human |
| Ruiyi Chen, Yash S Vakilna, Samuel Brandon Lassers, William C Tang, Gregory J Brewe. Hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from EC to DG and later similarity of axons from CA1 to EC. Journal of neural engineering. 2023-09-04. PMID:37666242. |
hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from ec to dg and later similarity of axons from ca1 to ec. |
2023-09-04 |
2023-09-07 |
Not clear |
| Seyed Mehdi Vatandoust, Javad Mahmoudi, Shahrbanoo Oryan, Fereshteh Farajdokht, Saeed Sadigh-Eteghad, Siamak Sandoghchian Shotorbani, Huaxi Xu, Delaram Eslimi Esfahan. Sericin improves memory and sociability impairments evoked by transient global cerebral ischemia through suppression of hippocampal oxidative stress, inflammation, and apoptosis. The Chinese journal of physiology. vol 66. issue 4. 2023-08-28. PMID:37635480. |
notably, ser decreased neuronal apoptotic cell death in the hippocampal dentate gyrus (dg) region, accompanied by suppression of neuroinflammation, downregulation of pro-apoptotic proteins (caspase-9, caspases-3, and bax), and upregulation of anti-apoptotic protein, bcl-2. |
2023-08-28 |
2023-09-07 |
mouse |
| Grace Minogue, Allegra Kawles, Antonia Zouridakis, Rachel Keszycki, Alyssa Macomber, Vivienne Lubbat, Nathan Gill, Qinwen Mao, Margaret E Flanagan, Hui Zhang, Rudolph Castellani, Eileen H Bigio, M-Marsel Mesulam, Changiz Geula, Tamar Gefe. Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with TDP-43. Annals of neurology. 2023-08-18. PMID:37592884. |
here, we investigated neuronal integrity and pathologic burden of tdp-43 and tau along the well-charted trisynaptic hippocampal circuit [dentate gyrus (dg), ca3, and ca1] in participants with amnestic dementia due to ad/tdp, amnestic dementia due to ad alone, or non-amnestic dementia due to tdp-43 proteinopathy associated with frontotemporal lobar degeneration (ftld-tdp). |
2023-08-18 |
2023-09-07 |
human |
| Deep R Sharma, Bokun Cheng, Rauhin Sahu, Xusheng Zhang, Rana Mehdizadeh, Divya Singh, Dumitru Iacobas, Praveen Ballab. Oestrogen treatment restores dentate gyrus development in premature newborns by IGF1 regulation. Journal of cellular and molecular medicine. 2023-08-18. PMID:37594177. |
prematurity diminishes neurogenesis and synaptogenesis in the hippocampal dentate gyrus (dg). |
2023-08-18 |
2023-09-07 |
rabbit |