| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jia-Rui Bi, Hai-Wei Zha, Qing-Lin Gao, Hui Wu, Zhen-Jiang Liu, Dong Su. Pleasant Odor Decreases Mouse Anxiety-like Behaviors by Regulating Hippocampal Endocannabinoid Signaling. International journal of molecular sciences. vol 25. issue 19. 2024-10-16. PMID:39409026. |
together, these results uncovered a novel mechanism by which linalool or 2-phenylethanol decreases mouse anxiety-like behaviors and increases dg activity likely through activating hippocampal retrograde endocannabinoid signaling. |
2024-10-16 |
2024-10-18 |
mouse |
| Daniel S Scott, Muthumeenakshi Subramanian, Jun Yamamoto, Carol A Tamming. Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events. Molecular psychiatry. 2024-10-15. PMID:39407000. |
we had previously studied a dentate gyrus (dg)-specific glun1 ko, which displays hippocampal hyperactivity and a psychosis-relevant behavioral phenotype. |
2024-10-15 |
2024-10-18 |
mouse |
| Daniel S Scott, Muthumeenakshi Subramanian, Jun Yamamoto, Carol A Tamming. Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events. Molecular psychiatry. 2024-10-15. PMID:39407000. |
dg inhibition during adolescence generates an increase in hippocampal activity in ca3 and ca1, impairs social cognition and spatial working memory, as well as shows evidence of increased activity in local field potentials as spontaneous synchronous bursts of activity, which we term hyper-synchronous events (hses) in hippocampus. |
2024-10-15 |
2024-10-18 |
mouse |
| Daniel S Scott, Muthumeenakshi Subramanian, Jun Yamamoto, Carol A Tamming. Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events. Molecular psychiatry. 2024-10-15. PMID:39407000. |
these results suggest a sensitive period in development in which the hippocampus is susceptible to dg inhibition resulting in hippocampal hyperactivity and psychosis-like behavioral outcomes. |
2024-10-15 |
2024-10-18 |
mouse |
| Jin Jin, Chonglei Fu, Jing Xia, Heyi Luo, Xianglian Wang, Si Chen, Huanhuan Mao, Kai Yuan, Lin Lu, Wei Xiong, Guichang Zo. Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer's disease through potentiating the function of extrasynaptic glycine receptors. Molecular psychiatry. 2024-10-12. PMID:39396064. |
cbd achieves its curative effect mainly through potentiating the function of inhibitory extrasynaptic glycine receptor (glyr) in hippocampal dentate gyrus (dg). |
2024-10-12 |
2024-10-15 |
mouse |
| Carolyn Twible, Rober Abdo, Chelsey Zhao, Qi Zhan. Hippocampal dentate granule cells in temporal lobe epilepsy: A morphometry and transcriptomic study. Neuropathology and applied neurobiology. vol 50. issue 5. 2024-10-08. PMID:39375854. |
the dentate gyrus (dg) plays a critical role in hippocampal circuitry, providing a "gate-like" function to the downstream cornu ammonis (ca) sectors. |
2024-10-08 |
2024-10-10 |
Not clear |
| Carolyn Twible, Rober Abdo, Chelsey Zhao, Qi Zhan. Hippocampal dentate granule cells in temporal lobe epilepsy: A morphometry and transcriptomic study. Neuropathology and applied neurobiology. vol 50. issue 5. 2024-10-08. PMID:39375854. |
to elucidate the role of the dg in mtle, we analysed hippocampal sclerosis (hs), no-hs, non-tle epilepsy control, and non-epilepsy control cohorts using morphometry and gene expression profiling techniques. |
2024-10-08 |
2024-10-10 |
Not clear |
| Stephen B McHugh, Vítor Lopes-Dos-Santos, Manfredi Castelli, Giuseppe P Gava, Sophie E Thompson, Shu K E Tam, Katja Hartwich, Brook Perry, Robert Toth, Timothy Denison, Andrew Sharott, David Dupre. Offline hippocampal reactivation during dentate spikes supports flexible memory. Neuron. 2024-09-25. PMID:39321790. |
hippocampal sharp-wave ripples (swrs) in the cornu ammonis (ca) region and dentate spikes (dss) in the dentate gyrus (dg) are prime candidate network events for supporting this offline process. |
2024-09-25 |
2024-09-28 |
mouse |
| Xiuting Qi, Xi Chen, Qi Luo, Lihan Liu, Dong An, Sha Sha, Yimei Du, Chunfeng Wu, Lei Che. TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus. Molecular neurobiology. 2024-09-23. PMID:39312069. |
aberrant neurogenesis in the adult hippocampal dentate gyrus (dg) contributes to synapse remodeling during temporal lobe epilepsy (tle). |
2024-09-23 |
2024-09-26 |
mouse |
| Xiuting Qi, Xi Chen, Qi Luo, Lihan Liu, Dong An, Sha Sha, Yimei Du, Chunfeng Wu, Lei Che. TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus. Molecular neurobiology. 2024-09-23. PMID:39312069. |
activation of trpv4 can modulate neurogenesis in the adult hippocampal dg. |
2024-09-23 |
2024-09-26 |
mouse |
| Xiuting Qi, Xi Chen, Qi Luo, Lihan Liu, Dong An, Sha Sha, Yimei Du, Chunfeng Wu, Lei Che. TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus. Molecular neurobiology. 2024-09-23. PMID:39312069. |
the present study examined whether trpv4 is responsible for the aberrant neurogenesis in the adult hippocampal dg during tle. |
2024-09-23 |
2024-09-26 |
mouse |
| Xiuting Qi, Xi Chen, Qi Luo, Lihan Liu, Dong An, Sha Sha, Yimei Du, Chunfeng Wu, Lei Che. TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus. Molecular neurobiology. 2024-09-23. PMID:39312069. |
herein, administration of a trpv4-specific antagonist, hc-067047, attenuated the enhanced neural stem cell proliferation in the adult hippocampal dg in mice following pilocarpine‑induced status epilepticus (pise). |
2024-09-23 |
2024-09-26 |
mouse |
| Nicole M Weston, Jakob C Green, Timothy N Keoprasert, Dong Su. Dendritic morphological development of traumatic brain injury-induced new neurons in the dentate gyrus is important for post-injury cognitive recovery and is regulated by Notch1. Experimental neurology. 2024-09-20. PMID:39303845. |
it is well established that neurogenesis in the dentate gyrus (dg) of the hippocampus is important for hippocampal dependent learning and memory functions. |
2024-09-20 |
2024-09-23 |
mouse |
| J J Rodríguez, E Gardenal, F Zallo, J Cabot, X Busquet. Early PSA-NCAM reduction in the dentate gyrus and impaired plasticity in the Alzheimer´s disease 3xTg-mice model. Acta histochemica. vol 126. issue 8. 2024-09-17. PMID:39288682. |
neurodegenerative diseases such as alzheimer´s (ad) and physiological ageing are characterized by a decline in neurogenesis and in the polysialylated isoforms of neural cell adhesion molecule (psa-ncam) expression within the hippocampus and specifically in the dentate gyrus (dg). |
2024-09-17 |
2024-09-20 |
mouse |
| Adam Hamed, Miron Bartosz Kursa, Wiktoria Mrozek, Krzysztof Piotr Piwoński, Monika Falińska, Konrad Danielewski, Emilia Rejmak, Urszula Włodkowska, Stepan Kubik, Rafał Czajkowsk. Spatio-temporal mechanisms of consolidation, recall and reconsolidation in reward-related memory trace. Molecular psychiatry. 2024-09-13. PMID:39271752. |
by employing machine learning analysis, we have shown this pattern is especially pronounced in the vta; furthermore, we also uncovered significant activity patterns in retrosplenial and prefrontal cortices, as well as in the dg and ca3 subfields of the hippocampus. |
2024-09-13 |
2024-09-16 |
Not clear |
| Jacopo Agrimi, Lucia Bernardele, Naeem Sbaiti, Marco Brondi, Donato D'Angelo, Marta Canato, Ivan Marchionni, Christian U Oeing, Giussy Barbara, Beatrice Vignoli, Marco Canossa, Nina Kaludercic, Gaya Spolverato, Anna Raffaello, Claudia Lodovichi, Marco Dal Maschio, Nazareno Paolocc. Reiterated male-to-female violence disrupts hippocampal estrogen receptor β expression, prompting anxiety-like behavior. iScience. vol 27. issue 9. 2024-09-04. PMID:39228787. |
rmfvi prompted anxiety-like behavior in female mice whose hippocampus displayed a marked neuronal loss and hampered neurogenesis, namely reduced brdu-dcx-positive nuclei and diminished dendritic arborization in the dentate gyrus (dg): effects paralleled by a substantial downregulation of the estrogen receptor β (erβ). |
2024-09-04 |
2024-09-06 |
mouse |
| Reihaneh Mohammadkhani, Iraj Salehi, Samaneh Safari, Reza Ghahremani, Alireza Komaki, Seyed Asaad Karim. Continuous exercise training rescues hippocampal long-term potentiation in the VPA rat model of Autism: Uncovering sex-specific effects. Neuroscience. 2024-08-30. PMID:39214164. |
the aim of the present study was to investigate the effects of interval training (it) and continuous training (ct) exercises on ltp in the hippocampal dentate gyrus (dg) neurons of valproic acid (vpa) rat model of autism. |
2024-08-30 |
2024-09-04 |
rat |
| Shenjia Gao, Ruling Shen, Jie Li, Yi Jiang, Hao Sun, Xinyi Wu, Xiya Li, Changhong Miao, Miao He, Jun Wang, Wankun Che. N-acetyltransferase 10 mediates cognitive dysfunction through the acetylation of GABA Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 36. 2024-08-27. PMID:39190359. |
our findings demonstrate that clp significantly upregulates nat10 expression and mrna acetylation in the excitatory neurons of the hippocampal dentate gyrus (dg). |
2024-08-27 |
2024-08-30 |
mouse |
| Zhengshan Liu, Yu H Sun, Yue Ren, Jessica Marie Perez, Daniel Scott, Carol Tamming. Upregulated solute-carrier family genes in the hippocampus of schizophrenia can be rescued by antipsychotic medications. Schizophrenia research. vol 272. 2024-08-25. PMID:39182310. |
our previous studies have found that functional changes in the hippocampal circuit from dentate gyrus (dg) to cornu ammonis 3 and 1 (ca3, ca1) are highly associated with schizophrenia (sz). |
2024-08-25 |
2024-08-28 |
human |
| Rocio Alfaro-Ruiz, Alejandro Martín-Belmonte, Carolina Aguado, Ana Esther Moreno-Martínez, Yugo Fukazawa, Rafael Lujá. Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology. Biological research. vol 57. issue 1. 2024-08-23. PMID:39175009. |
using quantitative sds-frl, we unravelled the molecular organisation of glun1 in seven excitatory synapse populations at a high spatial resolution in the ca1 and ca3 fields and the dg of the hippocampus in 12-month-old app/ps1 mice. |
2024-08-23 |
2024-08-25 |
mouse |