| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anqing Liu, Qingqiang Tu, Ming Huan. Feasibility study of PET/CT for the detection and localization of nervous system damage caused by trimethyltin chloride. Scientific reports. vol 15. issue 1. 2025-01-09. PMID:39779731. |
moreover, tmt induced neuronal damage within the cerebral cortex, hippocampal ca1, ca3 and dg regions as well as the cerebellum while also promoting gliosis surrounding the hippocampus. |
2025-01-09 |
2025-01-13 |
rat |
| Seyede Nazanin Zarneshan, Elham Arkan, Amir Kiani, Seyede Zahra Hosseini, Fatemeh Abbaszadeh, Sajad Fakhr. Protective effects of polydatin amphiphilic chitosan nanocarriers against an aluminum chloride-induced model of Alzheimer's disease in rats: relevance to its anti-inflammatory and antioxidant effects. Naunyn-Schmiedeberg's archives of pharmacology. 2025-01-09. PMID:39786589. |
npd also prevented morphological changes and increased neuronal survival in the ca2, ca4, and dg regions of the rat hippocampus. |
2025-01-09 |
2025-01-13 |
rat |
| Frank A Strnad, Ashley S Brown, Matthew Wieben, Emilio Cortes-Sanchez, Megan E Williams, Camille M Fun. Intrauterine Growth Restriction Alters Postnatal Hippocampal Dentate Gyrus Neuron and Microglia Morphology and Cytokine/Chemokine Milieu in Mice. Life (Basel, Switzerland). vol 14. issue 12. 2025-01-08. PMID:39768335. |
using a mouse model of hypertensive diseases of pregnancy (hdp) to replicate uteroplacental insufficiency (upi), we have previously shown that upi causes premature embryonic hippocampal dentate gyrus (dg) neurogenesis in iugr offspring. |
2025-01-08 |
2025-01-13 |
mouse |
| Frank A Strnad, Ashley S Brown, Matthew Wieben, Emilio Cortes-Sanchez, Megan E Williams, Camille M Fun. Intrauterine Growth Restriction Alters Postnatal Hippocampal Dentate Gyrus Neuron and Microglia Morphology and Cytokine/Chemokine Milieu in Mice. Life (Basel, Switzerland). vol 14. issue 12. 2025-01-08. PMID:39768335. |
we also examined dg microglia's morphology using immunofluorescent histochemistry and defined the hippocampal cytokine/chemokine milieu using luminex xmap technology. |
2025-01-08 |
2025-01-13 |
mouse |
| Zeinab Hamidizad, Mehri Kadkhodaee, Farzaneh Kianian, Mina Ranjbaran, Fatemeh Heidari, Behjat Seif. Neuroprotective Effects of Sodium Nitroprusside on CKD-Induced Cognitive Dysfunction in Rats: Role of CBS and Nrf2/HO-1 Pathway. Neuromolecular medicine. vol 27. issue 1. 2025-01-08. PMID:39775152. |
as predicted, the levels of bun and scr (both p < 0.001) and neuronal injury in the hippocampus (p < 0.001 for ca1; ca3; dg) and prefrontal cortex (p < 0.001) increased in ckd rats as well as 5/6nx induced reduction of nrf2 (both p < 0.001) /ho-1(p < 0.001; p < 0.01 respectively) pathway activity in the hippocampus and prefrontal cortex in ckd rats. |
2025-01-08 |
2025-01-13 |
rat |
| Zeinab Hamidizad, Mehri Kadkhodaee, Farzaneh Kianian, Mina Ranjbaran, Fatemeh Heidari, Behjat Seif. Neuroprotective Effects of Sodium Nitroprusside on CKD-Induced Cognitive Dysfunction in Rats: Role of CBS and Nrf2/HO-1 Pathway. Neuromolecular medicine. vol 27. issue 1. 2025-01-08. PMID:39775152. |
snp treatment significantly improved nrf2 (both p < 0.001) /ho-1 (p < 0.001; p < 0.05 respectively) pathways and neuronal injury (p < 0.001 for ca1; ca3; dg) in the hippocampus and prefrontal cortex in ckd rats as well as enhanced learning and memory ability in ckd rats. |
2025-01-08 |
2025-01-13 |
rat |
| L Daniel Estrella, Andrew J Trease, Lexi Sheldon, Nashanthea J Roland, Howard S Fox, Kelly L Stauc. Tau association with synaptic mitochondria coincides with energetic dysfunction and excitatory synapse loss in the P301S tauopathy mouse model. Neurobiology of aging. vol 147. 2025-01-08. PMID:39778459. |
we found a significant loss of excitatory synapses in the parietal cortex and hippocampal dentate gyrus (dg) of tau p301s mice. |
2025-01-08 |
2025-01-13 |
mouse |
| Sonia Irais Gonzalez-Cano, Ulises Peña-Rosas, Guadalupe Muñoz-Arenas, Diana Milena Torres-Cinfuentes, Samuel Treviño, Carolina Moran-Raya, Gonzalo Flores, Jorge Guevara, Alfonso Dia. Neuroprotective Effect of Curcumin-Metavanadate in the Hippocampus of Aged Rats. Synapse (New York, N.Y.). vol 79. issue 1. 2025-01-03. PMID:39748146. |
this work aimed to evaluate the coupling of metavanadate and curcumin (cuma-mv) on learning, memory, redox balance, neuroinflammation, and cell death in the hippocampal region (ca1 and ca3) and dentate gyrus (dg) of aged rats. |
2025-01-03 |
2025-01-05 |
rat |
| Avishek Roy, Anael Erhardt, Severine Deforges, Christophe Mull. Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 1. 2025-01-03. PMID:39751161. |
and mostly expressed in dentate gyrus (dg) network of hippocampus. |
2025-01-03 |
2025-01-05 |
Not clear |
| Jazmine D W Yaeger, Justin K Achua, Clarissa D Booth, Delan Khalid, Megan M John, Leighton J Ledesma, Trent L Greschke, Ashley M Potter, Chase B Howe, Kevin T Krupp, Justin P Smith, Patrick J Ronan, Cliff H Summer. Learned phenotypes emerge during social stress modifying hippocampal orexin receptor gene expression. Scientific reports. vol 14. issue 1. 2024-12-31. PMID:39738291. |
the hippocampus, studied for its role in learning, is divided into regions that designate the passage of neuronal signaling during memory formation, including dentate gyrus (dg), ca |
2024-12-31 |
2025-01-02 |
Not clear |
| Cheng Xue, Xiao-Hui Li, Hong-Qun Ding, Xin Qian, Meng-Yu Zhang, Kai Chen, Zi-Wei Wei, Ying Li, Jun-Hai Jia, Wei-Ning Zhan. Pyridoxine supplementation before puberty ameliorates MAM-induced cognitive and sensorimotor gating impairments. Metabolic brain disease. vol 40. issue 1. 2024-12-19. PMID:39699742. |
cannabinoid receptor interacting protein 1 (cnrip1) and cannabinoid receptor-1 (cb1r), which regulate memory, cognitive and motor activity, were detected in the prefrontal cortex (pfc) and hippocampus of the offspring rats, and the cell proliferation in the hippocampal dentate gyrus (dg) was also observed. |
2024-12-19 |
2024-12-21 |
rat |
| Cheng Xue, Xiao-Hui Li, Hong-Qun Ding, Xin Qian, Meng-Yu Zhang, Kai Chen, Zi-Wei Wei, Ying Li, Jun-Hai Jia, Wei-Ning Zhan. Pyridoxine supplementation before puberty ameliorates MAM-induced cognitive and sensorimotor gating impairments. Metabolic brain disease. vol 40. issue 1. 2024-12-19. PMID:39699742. |
these results indicate that prepuberty pyridoxine supplementation has a positive effect on the prevention of cognitive deficits and sensorimotor gating impairment in mam-induced schizophrenia-like rats, accompanied by changes in the cb1r and cnrip1 expression in pfc and hippocampus, as well as the regeneration of neurons in the dg region. |
2024-12-19 |
2024-12-21 |
rat |
| Xie Wang, Hong Chen, Xiaoyan Zhang, Nan Shao, Ze Chang, Daojun Xie, Juan Zhan. Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson's Disease. The American journal of Chinese medicine. 2024-12-17. PMID:39686792. |
in the wd copper-loaded rat model, evaluations using the morris water maze (mwm), y maze, hematoxylin and eosin staining, transmission electron microscopy (tem), and immunofluorescence (if) detection showed that dg significantly enhanced cognitive function recovery, reduced structural damage to hippocampal neurons, and protected mitochondrial integrity. |
2024-12-17 |
2024-12-21 |
rat |
| Xie Wang, Hong Chen, Xiaoyan Zhang, Nan Shao, Ze Chang, Daojun Xie, Juan Zhan. Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson's Disease. The American journal of Chinese medicine. 2024-12-17. PMID:39686792. |
this study elucidates the neuroprotective effect of dg on hippocampal neurons by activating the p38[formula: see text]-mediated fpt pathway, highlighting its efficacy as a potent monomer in traditional chinese medicine and illuminating its potential role in the clinical treatment of wdci. |
2024-12-17 |
2024-12-21 |
rat |
| Santiago Ronchetti, Florencia Labombarda, Julian Del Core, Paulina Roig, Alejandro F De Nicola, Luciana Pietraner. The phytoestrogen genistein improves hippocampal neurogenesis and cognitive impairment and decreases neuroinflammation in an animal model of metabolic syndrome. Journal of neuroendocrinology. 2024-12-16. PMID:39676329. |
expression of gfap was increased in the dg and ca1 areas of the hippocampus and treatment decreased astrogliosis in all of them. |
2024-12-16 |
2024-12-21 |
human |
| Lei Wu, Yan Sun, Zhangjie Wu, Ruiyi Liu, Ying Yin, Nga-Lee Wong, Wenzheng Ju, Hailou Zhan. A rich component of Fructus Aurantii, meranzin hydrate, exerts antidepressant effects via suppressing caspase4 to regulate glial cell and neuronal functions in the hippocampus. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 182. 2024-12-15. PMID:39675136. |
furthermore, mh could increase long-term potential (ltp) in the hippocampal dentate gyrus (dg) and activation of hippocampal caspase4 blocked mh's enhancement on neuronal activities and synaptic plasticity in the hippocampal dg. |
2024-12-15 |
2024-12-21 |
mouse |
| Xiujian Sun, Yexiang Chen, Ying Zhang, Tiantian Cheng, Huisheng Peng, Yanting Sun, Jing-Gen Liu, Chi X. Exosomes released from immature neurons regulate adult neural stem cell differentiation through microRNA-7a-5p. Stem cells (Dayton, Ohio). 2024-12-13. PMID:39670872. |
exosomes in the hippocampal dentate gyrus (dg) are essential for modulating the cell signaling controlling the neural differentiation of hippocampal neural stem cells (nscs), which may determine the level of hippocampal adult neurogenesis. |
2024-12-13 |
2024-12-22 |
mouse |
| Lei Tian, Jiang Chen, Xuan Liu, Yizhe Wei, Yiming Zhao, Yue Shi, Kang Li, Huanliang Liu, Wenqing Lai, Bencheng Li. Prenatal exposure on nanoplastics: a study of spatial transcriptomics in hippocampal offspring. Environmental pollution (Barking, Essex : 1987). 2024-12-07. PMID:39644950. |
moreover, the annotations of four hippocampus regions, ca1, ca2-3, dg, and hilus, as well as the go and gsva of several cell types, revealed deficiencies that can contribute to learning memory impairment. |
2024-12-07 |
2024-12-10 |
rat |
| Tahsin Nairuz, Jin-Chul Heo, Jong-Ha Le. Differential Glial Response and Neurodegenerative Patterns in CA1, CA3, and DG Hippocampal Regions of 5XFAD Mice. International journal of molecular sciences. vol 25. issue 22. 2024-11-27. PMID:39596222. |
differential glial response and neurodegenerative patterns in ca1, ca3, and dg hippocampal regions of 5xfad mice. |
2024-11-27 |
2024-11-29 |
mouse |
| Tahsin Nairuz, Jin-Chul Heo, Jong-Ha Le. Differential Glial Response and Neurodegenerative Patterns in CA1, CA3, and DG Hippocampal Regions of 5XFAD Mice. International journal of molecular sciences. vol 25. issue 22. 2024-11-27. PMID:39596222. |
in this study, the distinct patterns of glial response and neurodegeneration within the ca1, ca3, and dentate gyrus (dg) regions of the hippocampus were examined in 5xfad mice at 6 and 12 months of age. |
2024-11-27 |
2024-11-29 |
mouse |