| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Si Sun, Yitong Xu, Ningxi Yu, Meifeng Zhang, Jinghui Wang, Dong Wan, Zhen Tian, Huifeng Zh. Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway. Molecular neurobiology. 2023-07-13. PMID:37439957. |
catalpol remarkably promoted angiogenesis, promoted proliferation and differentiation of neural stem cells (nscs) in the subventricular zone (svz), and prevented neuronal loss and astrocyte activation in the ischemic cortex or hippocampal dentate gyrus (dg) in vivo. |
2023-07-13 |
2023-08-14 |
rat |
| Leonardo Oliveira Bittencourt, Aline Dionizio, Maria Karolina Martins Ferreira, Walessa Alana Bragança Aragão, Sabrina de Carvalho Cartágenes, Bruna Puty, Cristiane do Socorro Ferraz Maia, Fatemeh Vida Zohoori, Marília Afonso Rabelo Buzalaf, Rafael Rodrigues Lim. Prolonged exposure to high fluoride levels during adolescence to adulthood elicits molecular, morphological, and functional impairments in the hippocampus. Scientific reports. vol 13. issue 1. 2023-07-08. PMID:37422569. |
these changes were associated with modulation of the hippocampal proteomic profile, especially of proteins related to synaptic communication, and a neurodegenerative pattern in the ca3 and dg. |
2023-07-08 |
2023-08-14 |
mouse |
| Nerina M Villalba, Catalina Madarnas, Julieta Bressano, Viviana Sanchez, Alicia Brusc. Perinatal ethanol exposure affects cell populations in adult dorsal hippocampal neurogenic niche. Neuroscience research. 2023-07-07. PMID:37419388. |
in the adult brain, neurogenesis takes place in the dentate gyrus (dg) of the hippocampus and in the subventricular zone. |
2023-07-07 |
2023-08-14 |
mouse |
| Rafael de Jesús Macias-Velez, Martha Catalina Rivera-Cervantes, Alejandra Guadalupe Marín-López, Justo Murguía-Castill. Intranasal erythropoietin protects granular cells and reduces astrogliosis in the dentate gyrus after ischemic damage, an effect associated with molecular changes in erythropoietin and its receptor. Neuroscience letters. 2023-07-01. PMID:37393008. |
within the hippocampus, the ca1 and dentate gyrus (dg) regions are considered the most and the least susceptible to damage by cerebral ischemia, respectively. |
2023-07-01 |
2023-08-14 |
Not clear |
| Milenna T van Dijk, Ardesheer Talati, Pratik Kashyap, Karan Desai, Nora Kelsall, Marc Gameroff, Natalie Aw, Eyal Abraham, Breda Cullen, Jiook Cha, Christoph Anacker, Myrna M Weissman, Jonathan Posne. Dentate Gyrus Microstructure is associated with Resilience after Exposure to Maternal Stress Across Two Human Cohorts. Biological psychiatry. 2023-07-01. PMID:37393047. |
rodent models implicate the dentate gyrus (dg) of the hippocampus in the effects of ms on offspring depressive-like behaviors, but mechanisms in humans remain unclear. |
2023-07-01 |
2023-08-14 |
human |
| Feng Zhang, Kijun Yoon, Nam-Shik Kim, Guo-Li Ming, Hongjun Son. Cell-autonomous and non-cell-autonomous roles of NKCC1 in regulating neural stem cell quiescence in the hippocampal dentate gyrus. Stem cell reports. 2023-06-30. PMID:37390823. |
how nscs in the dentate gyrus (dg) of the hippocampus acquire their quiescence during early postnatal stages and continuously maintain quiescence in adulthood is poorly understood. |
2023-06-30 |
2023-08-14 |
Not clear |
| Jie Xu, Bowen Zheng, Yanmei Ma, Xiaopeng Zhang, Jianhua Cheng, Jing Yang, Peng Li, Jianzhong Zhang, Li Jing, Fang X. PI3K-AKT-mTOR signaling pathway regulates autophagy of hippocampal neurons in diabetic rats with chronic unpredictable mild stress. Behavioural brain research. 2023-06-30. PMID:37390967. |
the number of pyknotic neurons at cornu ammonis 1 (ca1) and dentate gyrus (dg) of the hippocampus in t2dd was significantly increased compared with cums and t2dm groups. |
2023-06-30 |
2023-08-14 |
rat |
| Rita Chaaya, Joel R Steele, Brian G Oliver, Hui Chen, Rita Machaalan. Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. Journal of chemical neuroanatomy. 2023-06-21. PMID:37343645. |
this study, using a mouse model, investigated the effects of exposure to e-vapour (± nicotine) and hfd (43% fat) consumption, on the expression of nicotinic acetylcholine receptor (nachr) subunits α3, α4, α7 and β2, apoptosis markers caspase-3 and tunel, microglial marker iba-1, and astrocyte marker gfap, in hippocampal subregions of dentate gyrus (dg) and cornu ammonis (ca) 1-3. |
2023-06-21 |
2023-08-14 |
mouse |
| Sanghee Yun, Ivan Soler, Fionya H Tran, Harley A Haas, Raymon Shi, Grace L Bancroft, Maiko Suarez, Christopher R de Santis, Ryan P Reynolds, Amelia J Eisc. Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity. Frontiers in behavioral neuroscience. vol 17. 2023-06-16. PMID:37324519. |
in humans and mice, discrimination and adaptation rely on the integrity of the hippocampal dentate gyrus (dg) which receives glutamatergic input from the entorhinal cortex (ec), including the lateral ec (lec). |
2023-06-16 |
2023-08-14 |
mouse |
| Guo Xiang, Xia Liu, Jiangong Wang, Shunshun Lu, Meng Yu, Yuhan Zhang, Bin Sun, Bin Huang, Xin-Yun Lu, Xingang Li, Di Zhan. Peroxisome proliferator-activated receptor-α activation facilitates contextual fear extinction and modulates intrinsic excitability of dentate gyrus neurons. Translational psychiatry. vol 13. issue 1. 2023-06-15. PMID:37322045. |
the dentate gyrus (dg) of the hippocampus encodes contextual information associated with fear, and cell activity in the dg is required for acquisition and extinction of contextual fear. |
2023-06-15 |
2023-08-14 |
mouse |
| Mia Borzello, Steve Ramirez, Alessandro Treves, Inah Lee, Helen Scharfman, Craig Stark, James J Knierim, Lara M Range. Assessments of dentate gyrus function: discoveries and debates. Nature reviews. Neuroscience. 2023-06-14. PMID:37316588. |
there has been considerable speculation regarding the function of the dentate gyrus (dg) - a subregion of the mammalian hippocampus - in learning and memory. |
2023-06-14 |
2023-08-14 |
Not clear |
| Siqi Peng, Wenzhen Gu, Wenxiu Zhu, Yan Zhuang, Xiuqi Yang, Yaochen Lv, Sibie Meng, Wei Xie, Moyi L. A new AAV tool for highly preferentially targeting hippocampal CA2. Molecular brain. vol 16. issue 1. 2023-06-11. PMID:37303064. |
mice hippocampus contains three prominent subregions, ca1, ca3 and dg and is well regarded as an essential multiple task processor for learning, memory and cognition based on tremendous studies on these three subregions. |
2023-06-11 |
2023-08-14 |
mouse |
| Virendra Tiwari, Akanksha Mishra, Sonu Singh, Shubha Shukl. Crosstalk between Adult Hippocampal Neurogenesis and Its Role in Alzheimer's Disease. ACS chemical neuroscience. 2023-06-01. PMID:37261380. |
neurogenesis in adult brain is associated with synaptic plasticity, learning, and memory in dentate gyrus (dg) of hippocampus and olfactory bulb. |
2023-06-01 |
2023-08-14 |
Not clear |
| Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li, Lingdong Kon. Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression. Acta pharmaceutica Sinica. B. vol 13. issue 5. 2023-05-30. PMID:37250149. |
neurogenesis decline in hippocampal dentate gyrus (dg) participates in stress-induced depressive-like behaviors, but the underlying mechanism remains poorly understood. |
2023-05-30 |
2023-08-14 |
mouse |
| Chiara Criscuolo, Elissavet Chartampila, Stephen D Ginsberg, Helen E Scharfma. Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer's disease neuropathology in a mouse model. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214931. |
however, the location where hippocampal bdnf protein is most highly expressed, the mossy fiber (mf) axons of dentate gyrus (dg) granule cells (gcs), has been understudied, and never in controlled |
2023-05-23 |
2023-08-14 |
mouse |
| Ricardo Insausti, Monica Muñoz-López, Ana Maria Insaust. The CA2 hippocampal subfield in humans: A review. Hippocampus. 2023-05-19. PMID:37204159. |
the longitudinal extent of ca2 is close to 30 mm, starting in the hippocampal head, 2.5 mm caudal to the dg and 3.5 mm caudal to the start of ca3, approximately 10 mm from the hippocampus rostral end. |
2023-05-19 |
2023-08-14 |
human |
| Michelle C Gulfo, Joseph J Lebowitz, Czarina Ramos, Dong-Woo Hwang, Kaoutsar Nasrallah, Pablo E Castill. Dopamine D2 receptors in mossy cells reduce excitatory transmission and are essential for hippocampal function. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205586. |
hilar mossy cells (mcs) are principal excitatory neurons of the dentate gyrus (dg) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety and epilepsy. |
2023-05-19 |
2023-08-14 |
Not clear |
| Carmen Vivar, Ben Peterson, Alejandro Pinto, Emma Janke, Henriette van Praa. Running throughout middle-age keeps eNeuro. 2023-05-15. PMID:37188520. |
in rodents, running increases the number of adult-born neurons in the dentate gyrus (dg) of the hippocampus, in association with improved synaptic plasticity and memory function. |
2023-05-15 |
2023-08-14 |
mouse |
| Ricardo Gómez-Oliva, Sergio Martínez-Ortega, Isabel Atienza-Navarro, Samuel Domínguez-García, Carlos Bernal-Utrera, Noelia Geribaldi-Doldán, Cristina Verástegui, Abdellah Ezzanad, Rosario Hernández-Galán, Pedro Nunez-Abades, Monica Garcia-Alloza, Carmen Castr. Rescue of neurogenesis and age-associated cognitive decline in SAMP8 mouse: Role of transforming growth factor-alpha. Aging cell. 2023-05-13. PMID:37177826. |
neuropathological aging is associated with memory impairment and cognitive decline, affecting several brain areas including the neurogenic niche of the dentate gyrus of the hippocampus (dg). |
2023-05-13 |
2023-08-14 |
mouse |
| Lei Ye, Shu Shu, Junqiu Jia, Min Sun, Siyi Xu, Xinyu Bao, Huijie Bian, Yi Liu, Meijuan Zhang, Xiaolei Zhu, Feng Bai, Yun X. Absent in melanoma 2 mediates aging-related cognitive dysfunction by acting on complement-dependent microglial phagocytosis. Aging cell. 2023-05-13. PMID:37177836. |
pattern separation (ps) dysfunction is a type of cognitive impairment that presents early during the aging process, and this deficit has been attributed to structural and functional alterations in the dentate gyrus (dg) of the hippocampus. |
2023-05-13 |
2023-08-14 |
mouse |