| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luísa Pinto, Joana Macedo, Bruna Araújo, Sandra Anjo, Tiago Silveira-Rosa, Patrícia Patrício, Fábio Teixeira, Bruno Manadas, Ana Joao Rodrigues, Angelo Lepore, António Salgado, Eduardo Gome. Glial-Restricted Precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation. Research square. 2023-04-10. PMID:37034743. |
to examine the role of newly formed glia, we transplanted glial restricted precursors (grps) into the adult hippocampal dentate gyrus (dg), or injected their secreted factors (secretome), into a previously validated transgenic gfap-tk rat line, in which cytogenesis is transiently compromised. |
2023-04-10 |
2023-08-14 |
rat |
| Xiangxian Ma, Qiongyu Li, Guanhong Chen, Junjie Xie, Min Wu, Fantao Meng, Jing Liu, Yong Liu, Di Zhao, Wentao Wang, Dan Wang, Cuilan Liu, Juanjuan Dai, Chen Li, Minghu Cu. Role of Hippocampal miR-132-3p in Modifying the Function of Protein Phosphatase Mg2+/Mn2+-dependent 1 F in Depression. Neurochemical research. 2023-04-10. PMID:37036545. |
our previous study has shown that protein phosphatase mg2+/mn2+-dependent 1f (ppm1f) in the hippocampal dentate gyrus (dg) displays significant regulatory effects in depression-related behaviors. |
2023-04-10 |
2023-08-14 |
mouse |
| Xiangxian Ma, Qiongyu Li, Guanhong Chen, Junjie Xie, Min Wu, Fantao Meng, Jing Liu, Yong Liu, Di Zhao, Wentao Wang, Dan Wang, Cuilan Liu, Juanjuan Dai, Chen Li, Minghu Cu. Role of Hippocampal miR-132-3p in Modifying the Function of Protein Phosphatase Mg2+/Mn2+-dependent 1 F in Depression. Neurochemical research. 2023-04-10. PMID:37036545. |
knockdown of mir-132-3p in hippocampal dg resulted in depression-related phenotypes and increased susceptibility to stress. |
2023-04-10 |
2023-08-14 |
mouse |
| Xiangxian Ma, Qiongyu Li, Guanhong Chen, Junjie Xie, Min Wu, Fantao Meng, Jing Liu, Yong Liu, Di Zhao, Wentao Wang, Dan Wang, Cuilan Liu, Juanjuan Dai, Chen Li, Minghu Cu. Role of Hippocampal miR-132-3p in Modifying the Function of Protein Phosphatase Mg2+/Mn2+-dependent 1 F in Depression. Neurochemical research. 2023-04-10. PMID:37036545. |
mir-132-3p overexpression in hippocampal dg alleviated cus-induced depression-related performance. |
2023-04-10 |
2023-08-14 |
mouse |
| Fatih Mete, Signem Eyuboglu, Ayca Vitrinel, Ulkan Kilic, Cihan Suleyman Erdogan, Ertugrul Kilic, Bayram Yilma. Hyperthermia alters neurobehavior by affecting cell proliferation and neuronal survival in young male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2023-04-08. PMID:37029601. |
neuronal survival, apoptosis, and cell proliferation were investigated in cortex, hippocampal dentate gyrus (dg) and ca1 regions, and corpus callosum (cc). |
2023-04-08 |
2023-08-14 |
rat |
| Ling Zhao, Thomas W Mühleisen, Dominique I Pelzer, Bettina Burger, Eva C Beins, Andreas J Forstner, Stefan Herms, Per Hoffmann, Katrin Amunts, Nicola Palomero-Gallagher, Sven Cicho. Relationships between neurotransmitter receptor densities and expression levels of their corresponding genes in the human hippocampus. NeuroImage. 2023-04-08. PMID:37030412. |
we combined in vitro receptor autoradiography and rna sequencing to quantify, in the same tissue samples (7 subjects), the densities of 14 receptors and expression levels of their corresponding 43 genes in the cornu ammonis (ca) and dentate gyrus (dg) of human hippocampus. |
2023-04-08 |
2023-08-14 |
human |
| Lang Wen, Xiaoli Yang, Zujun Wu, Shumei Fu, Yaxi Zhan, Zuolong Chen, Danlei Bi, Yong She. The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus. Cell reports. vol 42. issue 4. 2023-04-07. PMID:37027303. |
furthermore, cd59 deficiency impairs gabaergic synaptic transmission in the hippocampal dentate gyrus (dg). |
2023-04-07 |
2023-08-14 |
Not clear |
| Camille M Fun. Effects of intrauterine growth restriction on embryonic hippocampal dentate gyrus neurogenesis and postnatal critical period of synaptic plasticity that govern learning and memory function. Frontiers in neuroscience. vol 17. 2023-04-03. PMID:37008232. |
the hippocampus, composed of the dentate gyrus (dg) and cornu ammonis (ca) subregions, is an important gray matter structure critical to learning and memory, and is particularly vulnerable to the chronic hypoxic-ischemic effects of upi. |
2023-04-03 |
2023-08-14 |
mouse |
| Camille M Fun. Effects of intrauterine growth restriction on embryonic hippocampal dentate gyrus neurogenesis and postnatal critical period of synaptic plasticity that govern learning and memory function. Frontiers in neuroscience. vol 17. 2023-04-03. PMID:37008232. |
we will follow with data generated using our laboratory's mouse model of iugr, that mimics the human iugr phenotype, to dissect at the cellular and molecular alterations in embryonic hippocampal dg neurogenesis. |
2023-04-03 |
2023-08-14 |
mouse |
| JiaLing Zhong, ChunLin Li, LuoFang Peng, Yudan Pan, Yong Yang, QuLian Guo, Tao Zhon. Repeated neonatal isoflurane exposure facilitated stress-related fear extinction impairment in male mice and was associated with ΔFosB accumulation in the basolateral amygdala and the hippocampal dentate gyrus. Behavioural brain research. 2023-04-01. PMID:37003493. |
the corticosterone (cort) response during cvs and the immunohistochemical levels of Δfosb and c-fos expression in the basolateral amygdala (bla) and the hippocampal dentate gyrus (dg) after the extinction retrieval test were also investigated. |
2023-04-01 |
2023-08-14 |
mouse |
| JiaLing Zhong, ChunLin Li, LuoFang Peng, Yudan Pan, Yong Yang, QuLian Guo, Tao Zhon. Repeated neonatal isoflurane exposure facilitated stress-related fear extinction impairment in male mice and was associated with ΔFosB accumulation in the basolateral amygdala and the hippocampal dentate gyrus. Behavioural brain research. 2023-04-01. PMID:37003493. |
furthermore, neonatal isoflurane exposure facilitated cvs-mediated Δfosb accumulation in the bla and the hippocampal dg, which may have been responsible for c-fos expression deficits and fear extinction impairment. |
2023-04-01 |
2023-08-14 |
mouse |
| b' Sinan Saral, Atilla Top\\xc3\\xa7u, Mehmet Alkanat, Tolga Mercantepe, Zafer \\xc5\\x9eahin, Kerimali Aky\\xc4\\xb1ld\\xc4\\xb1z, Kader Semra Karata\\xc5\\x9f, Lamiye Y\\xc4\\xb1ld\\xc4\\xb1z, Levent T\\xc3\\xbcmkaya, Zihni A\\xc3\\xa7ar Yaz\\xc4\\xb1c\\xc4\\xb. Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus. Journal of chemical neuroanatomy. 2023-03-31. PMID:37001681.' |
histological findings showed that agomelatine treatment reduced pyramidal neuron damage in hippocampal dg, ca1 and ca3. |
2023-03-31 |
2023-08-14 |
rat |
| Laura J Mahady, Sylvia E Perez, Michael Malek-Ahmadi, Elliott J Mufso. Oligomeric, phosphorylated, and truncated tau and spliceosome pathology within the entorhinal-hippocampal connectome across stages of Alzheimer's disease. The Journal of comparative neurology. 2023-03-29. PMID:36989381. |
here, we used quantitative immunohistochemistry to determine the density of posttranslational oligomeric (toc1 and tnt1), phosphorylated (at8), and late truncated (tauc3) tau epitopes within the mtl subfields including entorhinal cortex (ec) layer ii, subiculum, cornu ammonis (ca) subfields, and dentate gyrus (dg) in subjects who died with a clinical diagnosis of no cognitive impairment (nci), mild cognitive impairment (mci), and ad. |
2023-03-29 |
2023-08-14 |
human |
| Somayeh Hajipour, Maryam Khombi Shooshtari, Yaghoob Farbood, Seyed Ali Mard, Alireza Sarkaki, Homeira Moradi Chameh, Neda Sistani Karampour, Samireh Ghafour. Fingolimod administration following hypoxia induced neonatal seizure can restore impaired long-term potentiation and memory performance in adult rats. Neuroscience. 2023-03-29. PMID:36990271. |
long-term potentiation (ltp) was recorded from hippocampal dentate gyrus region (dg) following stimulation of perforant pathway (pp). |
2023-03-29 |
2023-08-14 |
rat |
| Zongyue Sun, Meiqin Wang, Lei Xu, Qiongyu Li, Zhongyi Zhao, Xuehao Liu, Fantao Meng, Jing Liu, Wentao Wang, Chen Li, Shujun Jian. PPARγ/Adiponectin axis attenuates methamphetamine-induced conditional place preference via the hippocampal AdipoR1 signaling pathway. Progress in neuro-psychopharmacology & biological psychiatry. 2023-03-27. PMID:36972780. |
the meth induced adult male c57/bl6j mice model were used for testing the therapeutic activities of intraperitoneal injection of adiporon or rosiglitazone, and adipor1 overexpression in hippocampal dentate gyrus (dg), and chemogenetic inhibiting the neural activity of dg, and the changes of neurotrophic factors, synaptic molecules, and glutamate receptors, and inflammatory cytokines were also measured. |
2023-03-27 |
2023-08-14 |
mouse |
| Zongyue Sun, Meiqin Wang, Lei Xu, Qiongyu Li, Zhongyi Zhao, Xuehao Liu, Fantao Meng, Jing Liu, Wentao Wang, Chen Li, Shujun Jian. PPARγ/Adiponectin axis attenuates methamphetamine-induced conditional place preference via the hippocampal AdipoR1 signaling pathway. Progress in neuro-psychopharmacology & biological psychiatry. 2023-03-27. PMID:36972780. |
the observed inhibitory neural activity of the hippocampal dentate gyrus (dg) induced via a chemogenetic approach produced a therapeutic effect on the meth-induced cpp behavior. |
2023-03-27 |
2023-08-14 |
mouse |
| Yujeong Lee, Hee Ra Park, Joo Yeon Lee, Jaehoon Kim, Seonguk Yang, Chany Lee, Kipom Kim, Hyung Sik Kim, Seung-Cheol Chang, Jaewon Le. Low-dose curcumin enhances hippocampal neurogenesis and memory retention in young mice. Archives of pharmacal research. 2023-03-22. PMID:36947339. |
adult neurogenesis generates new functional neurons from adult neural stem cells in various regions, including the subventricular zone (svz) of the lateral ventricles and subgranular zone (sgz) of hippocampal dentate gyrus (dg). |
2023-03-22 |
2023-08-14 |
mouse |
| Anamika, Anima Roy, Surendra K Trigu. Hippocampus mitochondrial MnSOD activation by a SIRT3 activator, honokiol, correlates with its deacetylation and upregulation of FoxO3a and PGC1α in a rat model of ammonia neurotoxicity. Journal of cellular biochemistry. 2023-03-16. PMID:36922709. |
this was consistent with the reduced level of immuno-stained foxo3a and pgc1α proteins in hippocampus dg, ca1 and ca3 regions of those mohe rats. |
2023-03-16 |
2023-08-14 |
rat |
| Rada Jeremic, Sanja Pekovic, Irena Lavrnja, Ivana Bjelobaba, Marina Djelic, Sanja Dacic, Predrag Brki. Hyperbaric Oxygenation Prevents Loss of Immature Neurons in the Adult Hippocampal Dentate Gyrus Following Brain Injury. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36901691. |
since the role of nscs in recovery from brain injury is still unclear, the purpose of this study was to investigate the effects of sensorimotor cortex ablation (sca) and hbo treatment (hbot) on the processes of neurogenesis in the adult dentate gyrus (dg), a region of the hippocampus that is the site of adult neurogenesis. |
2023-03-11 |
2023-08-14 |
rat |
| Diego A González-Franco, Rogelio Pegueros-Maldonado, América M Cruz-Quiroz, Norma Serafín, Paola C Bello-Medina, Roberto A Prado-Alcalá, Gina L Quirart. Intense inhibitory avoidance training increases nuclear-phosphorylated glucocorticoid receptors in neurons of CA1 of hippocampus and ventral caudate putamen. Brain research. 2023-03-11. PMID:36906227. |
the gr is present in the hippocampus with a high concentration in ca1 and dentate gyrus (dg), and a smaller proportion in ca3, and sparsely present in the caudate putamen (cpu); both structures are involved in memory consolidation of ia. |
2023-03-11 |
2023-08-14 |
rat |