| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie Doan, Céline Defaix, Indira Mendez-David, Alain M Gardier, Romain Colle, Emmanuelle Corruble, Josephine C McGowan, Denis J David, Jean-Philippe Guilloux, Laurent Tritschle. Intrahippocampal injection of a selective blocker of NMDA receptors containing the GluN2B subunit, Ro25-6981, increases glutamate neurotransmission and induces antidepressant-like effects. Fundamental & clinical pharmacology. 2023-05-10. PMID:37161789. |
thus, (αr)-(4-hydroxyphenyl)-(βs)-methyl-4-(phenylmethyl)-1-piperidinepropanol (ro25-6981), a selective antagonist of the glun2b subunit, was acutely administered locally into the ventral dg (vdg, 1μg each side) following a chronic fluoxetine (18 mg/kg/day) treatment - known to increase adult hippocampal neurogenesis - in a mouse model of anxiety/depression. |
2023-05-10 |
2023-08-14 |
mouse |
| Christos Panagiotis Lisgaras, Helen E Scharfma. Interictal Spikes in Animal Models of Alzheimer's Disease: Dominance of the Dentate Gyrus and Cholinergic Control by Medial Septum. bioRxiv : the preprint server for biology. 2023-05-10. PMID:37163065. |
because hippocampus and cortex exhibit altered excitability in ad models, we asked where iis are largest along the cortical-ca1-dentate gyrus (dg) dorso-ventral axis. |
2023-05-10 |
2023-08-14 |
mouse |
| Jiyeon K Denninger, Lisa N Miller, Ashley E Walters, Manal Hosawi, Gwendolyn Sebring, Joshua D Rieskamp, Tianli Ding, Raina Rindani, Kelly S Chen, Sakthi Senthilvelan, Abigail Volk, Fangli Zhao, Candice Askwith, Elizabeth D Kirb. Neural stem and progenitor cells support and protect adult hippocampal function via vascular endothelial growth factor secretion. bioRxiv : the preprint server for biology. 2023-05-10. PMID:37163097. |
adult neural stem and progenitor cells (nspcs) reside in the dentate gyrus (dg) of the hippocampus throughout the lifespan of most mammalian species. |
2023-05-10 |
2023-08-14 |
Not clear |
| Mohammadmehdi Hadipour, Soheila Refahi, Zohreh Jangravi, Gholam Hossein Meftah. Tarooneh extract relieves anxiety-like behaviors and cognitive deficits by inhibiting synaptic loss in the hippocampus and frontal cortex in rats subjected to chronic restraint stress. 3 Biotech. vol 13. issue 5. 2023-05-08. PMID:37152003. |
in this study, we evaluated the protective effects of tarooneh in the anxiety-like behavior, cognitive deficit, and neuronal damages in the ca1, ca3, and dentate gyrus (dg) regions of the hippocampus and frontal cortex neurons employing a rat model of chronic restraint stress. |
2023-05-08 |
2023-08-14 |
rat |
| Mohammadmehdi Hadipour, Soheila Refahi, Zohreh Jangravi, Gholam Hossein Meftah. Tarooneh extract relieves anxiety-like behaviors and cognitive deficits by inhibiting synaptic loss in the hippocampus and frontal cortex in rats subjected to chronic restraint stress. 3 Biotech. vol 13. issue 5. 2023-05-08. PMID:37152003. |
in conclusion, our results suggest that tarooneh prevented and improved anxiety-like behavior, cognitive deficit, and neuronal damages in the ca1, ca3, and dg regions of the hippocampus and frontal cortex neurons induced by chronic restraint stress. |
2023-05-08 |
2023-08-14 |
rat |
| Arumugam Kamaladevi, Koilmani Emmanuvel Raja. Antibiotic treatment during post-natal reverses behavioural and molecular alterations in experimental meningitis survivor rat model. Neurotoxicology and teratology. 2023-05-04. PMID:37142063. |
in addition, ngf expression was reduced in dentate gyrus (dg) and ca1 regions of hippocampus. |
2023-05-04 |
2023-08-14 |
rat |
| Kelsey L Canada, Roya Homayouni, Qijing Yu, Da' Jonae Foster, Sruthi Ramesh, Sarah Raz, Ana M Daugherty, Noa Ofe. Household socioeconomic status relates to specific hippocampal subfield volumes across development. Hippocampus. 2023-05-03. PMID:37132590. |
bilateral cornu ammonis (ca) 1-2, combined ca3-dentate gyrus (dg), and subiculum (sub) volumes were measured by highly reliable manual segmentation of high-resolution t2-weighted images and adjusted for intracranial volume. |
2023-05-03 |
2023-08-14 |
Not clear |
| Chi-Hsun Chang, Sukhan Zehra, Adrian Nestor, Andy C H Le. Using image reconstruction to investigate face perception in amnesia. Neuropsychologia. 2023-04-29. PMID:37119985. |
the present study employed a behavioral-based image reconstruction approach to reveal the pictorial representations of face perception in two amnesic patients: da, who has an extensive bilateral mtl lesion that extends beyond the mtl in the right hemisphere, and bl, who has damage to the hippocampal dentate gyrus (dg). |
2023-04-29 |
2023-08-14 |
human |
| Shaghayegh Modaberi, Haleh Amirteymori, Somaye Mesgar, Kiarash Eskandari, Abbas Haghparas. The blockade of orexin receptors within the dentate gyrus of the hippocampus attenuated methamphetamine-induced reward learning during conditioning place preference. Pharmacology, biochemistry, and behavior. 2023-04-26. PMID:37100179. |
previous studies showed that the orexinergic system in the dentate gyrus (dg) region of the hippocampus affects the conditioning (acquisition) and post-conditioning (expression) phases of morphine-induced conditioned place preference (cpp). |
2023-04-26 |
2023-08-14 |
rat |
| Shaghayegh Modaberi, Haleh Amirteymori, Somaye Mesgar, Kiarash Eskandari, Abbas Haghparas. The blockade of orexin receptors within the dentate gyrus of the hippocampus attenuated methamphetamine-induced reward learning during conditioning place preference. Pharmacology, biochemistry, and behavior. 2023-04-26. PMID:37100179. |
the present study aimed to determine the role of orexin-1 and -2 receptors in the hippocampal dg in meth cpp acquisition and expression. |
2023-04-26 |
2023-08-14 |
rat |
| Mahsa Mohammadi, Kiarash Eskandari, Ronak Azizbeigi, Abbas Haghparas. The inhibitory effect of cannabidiol on the rewarding properties of methamphetamine in part mediates by interacting with the hippocampal D1-like dopamine receptors. Progress in neuro-psychopharmacology & biological psychiatry. 2023-04-26. PMID:37100273. |
therefore, given that involving d1rs in reward-related behaviors and the encouraging results of cbd in attenuating the psychostimulant's rewarding effects, the present study sought to investigate the role of d1rs of the hippocampal dentate gyrus (dg) in the inhibitory effects of cbd on the acquisition and expression of meth-induced cpp. |
2023-04-26 |
2023-08-14 |
rat |
| B M Romero-Torres, Y A Alvarado-Ramírez, S R Duran-Alonzo, A E Ruiz-Contreras, A Herrera-Solis, O Amancio-Belmont, O E Prospéro-García, M Méndez-Día. A potential role of hippocampus on impulsivity and alcohol consumption though CB1R. Pharmacology, biochemistry, and behavior. 2023-04-23. PMID:37088449. |
to further understand the potential role of the hippocampal cb1r in impulsive and drug seeking behaviors, we characterized impulsivity in adolescent and adult male rats, by means of a delay discounting task (ddt) by evaluating preference and seeking motivation for alcohol (10 % v/v) consumption, and analyzing cb1r expression in ca1, ca3 and the dentate gyrus (dg) of the hpp as well as in the medial prefrontal cortex (mpfc). |
2023-04-23 |
2023-08-14 |
rat |
| B M Romero-Torres, Y A Alvarado-Ramírez, S R Duran-Alonzo, A E Ruiz-Contreras, A Herrera-Solis, O Amancio-Belmont, O E Prospéro-García, M Méndez-Día. A potential role of hippocampus on impulsivity and alcohol consumption though CB1R. Pharmacology, biochemistry, and behavior. 2023-04-23. PMID:37088449. |
our data further support the role of the hippocampus in impulsivity with the potential involvement of the endocannabinoid system, considering that cb1r in ca3 and dg is higher in adolescents, who display impulsivity and alcohol seeking and consumption. |
2023-04-23 |
2023-08-14 |
rat |
| S Vinci-Booher, M Schlichting, A Preston, F Pestill. Development of human hippocampal subfield microstructure related to associative inference. bioRxiv : the preprint server for biology. 2023-04-17. PMID:37066304. |
we found that the dg was related to memory-based inference performance and that the sub, a subfield outside of the hippocampus proper, was related to perception-based inference; neither relationship interacted with age. |
2023-04-17 |
2023-08-14 |
human |
| Muhammad N Arshad, Alejandro Pinto, Henriette van Praag, Janice R Naegel. Altered connectomes of adult-born granule cells following engraftment of GABAergic progenitors in the mouse hippocampus. Progress in neurobiology. 2023-04-15. PMID:37061022. |
adult neurogenesis occurs in the dentate gyrus (dg) of the rodent hippocampus throughout life, producing new granule cells (gcs) that migrate from a stem cell niche called the subgranular zone (sgz) into the adjacent granule cell layer (gcl). |
2023-04-15 |
2023-08-14 |
mouse |
| Marília da Cunha Feio Leal, Fabio Leite do Amaral Junior, Bernardo Freire da Silva Arruda, Juliana Ayumi Azevedo Kurosawa, Amanda Almeida Vieira, Júlia Corrêa Campos Maia, Viviana Virgínia Bezerra Scalfoni, Antonio Morais da Silveira Junior, Matheus Oliveira Feijó, Fernanda Beatriz Araújo de Albuquerque, Maria Helena Moutinho Marta, Marina Paula Nobre Normando, Alana Gabriele Oliveira Cabeça da Silva, Fernanda Catharina Pires da Trindade, Fabíola de Carvalho Chaves de Siqueira Mendes, Marcia Consentino Kronka Sosthene. The Masticatory Activity Interference in Quantitative Estimation of CA1, CA3 and Dentate Gyrus Hippocampal Astrocytes of Aged Murine Models and under Environmental Stimulation. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047502. |
thus, considering this context, the present study evaluated the effects of deprivation and rehabilitation of masticatory activity, aging, and environmental enrichment on the stereological quantification of hippocampal astrocytes from layers ca1, ca3, and dg. |
2023-04-13 |
2023-08-14 |
mouse |
| Sang Hoon Kim, Douglas GoodSmith, Stephanie J Temme, Fumika Moriya, Guo-Li Ming, Kimberly M Christian, Hongjun Song, James J Knieri. Global remapping in granule cells and mossy cells of the mouse dentate gyrus. Cell reports. vol 42. issue 4. 2023-04-12. PMID:37043350. |
unique among hippocampal subregions, the dentate gyrus (dg) has two excitatory populations of place cells, granule cells and mossy cells, which are among the least and most active spatially modulated cells in the hippocampus, respectively. |
2023-04-12 |
2023-08-14 |
mouse |
| Chen Zhang, Zixian He, Zheren Tan, Fafa Tia. Silencing of dentate gyrus inhibits mossy fiber sprouting and prevents epileptogenesis through NDR2 kinase in pentylenetetrazole kindling rat model of TLE. PloS one. vol 18. issue 4. 2023-04-12. PMID:37043471. |
furthermore, our results showed that injection of avv vector expressing ndr2 into dg induced upregulation of ndr2 in the hippocampus, and over expression of ndr2 in the hippocampus promote mfs and block protective effect of chemogenetic silencing of dg on epileptogenesis. |
2023-04-12 |
2023-08-14 |
rat |
| Chen Zhang, Zixian He, Zheren Tan, Fafa Tia. Silencing of dentate gyrus inhibits mossy fiber sprouting and prevents epileptogenesis through NDR2 kinase in pentylenetetrazole kindling rat model of TLE. PloS one. vol 18. issue 4. 2023-04-12. PMID:37043471. |
overall, we concluded that silencing of dg inhibits mfs and prevents epileptogenesis through ndr2 in the hippocampus in the ptz kindling rat model of tle, thereby providing a possible strategy to prevent epileptogenesis. |
2023-04-12 |
2023-08-14 |
rat |
| Kelsey D McDermott, M Agustina Frechou, Jake T Jordan, Sunaina S Martin, J Tiago Gon ßalve. Delayed formation of neural representations of space in aged mice. bioRxiv : the preprint server for biology. 2023-04-10. PMID:37034736. |
the hippocampal dentate gyrus (dg) is important for processing spatial information in the brain and is particularly vulnerable to aging, yet its sparse activity has led to difficulties in assessing changes in this area. |
2023-04-10 |
2023-08-14 |
mouse |