| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kimberly L P Long, Sandra E Muroy, Siamak K Sorooshyari, Mee Jung Ko, Yanabah Jaques, Peter Sudmant, Daniela Kaufe. Transcriptomic profiles of stress susceptibility and resilience in the amygdala and hippocampus. bioRxiv : the preprint server for biology. 2023-02-17. PMID:36798395. |
the dentate gyrus (dg) of the hippocampus and the basolateral nucleus of the amygdala (bla) are key limbic regions that are susceptible to the neural and hormonal effects of stress. |
2023-02-17 |
2023-08-14 |
rat |
| Anita Lewczuk, Anna Boratyńska-Jasińska, Barbara Zabłock. Validation of the Reference Genes for Expression Analysis in the Hippocampus after Transient Ischemia/Reperfusion Injury in Gerbil Brain. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36769080. |
in cornu ammonnis 2-3, dentate gyrus (ca2-3,dg) regions of the hippocampus, neurons are resistant to 5-min ischemia/reperfusion (i/r) insult, while cornu ammonnis 1 (ca1) is found to be i/r-vulnerable. |
2023-02-11 |
2023-08-14 |
Not clear |
| Yongjie Zhou, Xiaoxiao Zou, Ruifang Feng, Xin Zhan, Hui Hong, Yongkang Luo, Yuqing Ta. Improvement of Spatial Memory and Cognitive Function in Mice via the Intervention of Milk Fat Globule Membrane. Nutrients. vol 15. issue 3. 2023-02-11. PMID:36771241. |
also, the immunohistochemical results demonstrated a significantly higher number of neurons in group m compared with group c, especially in the hippocampal dentate gyrus (dg) area. |
2023-02-11 |
2023-08-14 |
mouse |
| Ramin Abdi Dezfouli, Sajad Mazaheri, Zahra Mousavi, Abbas Haghparas. Restraint stress induced the antinociceptive responses via the dopamine receptors within the hippocampal CA1 area in animal model of persistent inflammatory pain. Behavioural brain research. vol 443. 2023-02-10. PMID:36764008. |
a prior study showed that dopamine receptors within the hippocampal dg have a critical role in antinociception induced by forced swim stress (fss), as a physical stressor, in the presence of formalin irritation. |
2023-02-10 |
2023-08-14 |
rat |
| Sanghee Yun, Ivan Soler, Fionya Tran, Harley A Haas, Raymon Shi, Grace L Bancroft, Maiko Suarez, Chris R de Santis, Ryan P Reynolds, Amelia J Eisc. Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity. bioRxiv : the preprint server for biology. 2023-02-07. PMID:36747871. |
in humans and mice, discrimination and adaptation rely on integrity of the hippocampal dentate gyrus (dg) which both receive glutamatergic input from the entorhinal cortex (ec), including the lateral ec (lec). |
2023-02-07 |
2023-08-14 |
mouse |
| Annalisa Adinolfi, Gabriele Di Sante, Luca Rivignani Vaccari, Maria Tredicine, Francesco Ria, Davide Bonvissuto, Valentina Corvino, Claudio Sette, Maria Concetta Gelos. Regionally restricted modulation of Frontiers in molecular neuroscience. vol 15. 2023-01-30. PMID:36710925. |
in this study, we investigated several parameters of neuroplasticity in the hippocampus of the experimental autoimmune encephalomyelitis (eae) sjl/j mouse model, characterized by rostral inflammatory and demyelinating lesions similar to relapsing-remitting ms. by combining morphological and molecular analyses, we found that the hippocampus undergoes extensive inflammation in eae-mice, more pronounced in the ca3 and dentate gyrus (dg) subfields than in the ca1, associated with changes in gabaergic circuitry, as indicated by the increased expression of the interneuron marker parvalbumin selectively in ca3. |
2023-01-30 |
2023-08-14 |
mouse |
| Ran Zhang, Meixuan Chen, Zhongfang Deng, Lingchao Kong, Bing Shen, Lesha Zhan. Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury. Pharmaceutics. vol 15. issue 1. 2023-01-21. PMID:36678674. |
the co-localization results showed that bmecs, but not astrocytes, microglia, or neurons, presented mostly tunel-positive signals, especially in the dentate gyrus (dg) area of the hippocampus. |
2023-01-21 |
2023-08-14 |
rat |
| Shi-Hao Wu, Xiao Li, Dong-Dong Qin, Lin-Heng Zhang, Tian-Lin Cheng, Zhi-Fang Chen, Bin-Bin Nie, Xiao-Feng Ren, Jing Wu, Wen-Chao Wang, Ying-Zhou Hu, Yi-Lin Gu, Long-Bao Lv, Yong Yin, Xin-Tian Hu, Zi-Long Qi. Induction of core symptoms of autism spectrum disorder by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys. Science bulletin. vol 66. issue 9. 2023-01-19. PMID:36654241. |
here we induced genetic mutations in mecp2, a critical gene linked to rett syndrome (rtt) and autism spectrum disorders (asd), in the hippocampus (dg and ca1-4) of adolescent rhesus monkeys (macaca mulatta) in vivo via adeno-associated virus (aav)-delivered staphylococcus aureus cas9 with small guide rnas (sgrnas) targeting mecp2. |
2023-01-19 |
2023-08-14 |
human |
| Yunyun Li, Xiaodie Liu, Qianqian Fu, Wenxiang Fan, Xiaomei Shao, Jianqiao Fang, Jing-Gen Liu, Chi X. Electroacupuncture ameliorates depression-like behaviors comorbid to chronic neuropathic pain via Tet1-mediated restoration of adult neurogenesis. Stem cells (Dayton, Ohio). 2023-01-17. PMID:36648299. |
thus, we conclude that ea stimulation restores inhibited tet1 expression in hippocampal nscs of mice with chronic neuropathic pain, and increased tet1 expression ameliorates hypermethylation of prox1 and restores normal adult neurogenesis in the ventral dg, which contributes to the long-term antidepressant effect of ea. |
2023-01-17 |
2023-08-14 |
mouse |
| Yoon Ji Kwon, Sojeong Pak, Sunggu Yang, Sungchil Yan. Electrophysiological measurements of synaptic connectivity and plasticity in the longitudinal dentate gyrus network from mouse hippocampal slices. STAR protocols. vol 4. issue 1. 2023-01-12. PMID:36633949. |
longitudinal synaptic connections between dentate gyrus (dg) granule neurons in the hippocampus have been found to be correlated with increased anxiety. |
2023-01-12 |
2023-08-14 |
mouse |
| Masoumeh Nazari, Seyed Asaad Karimi, Somayeh Komaki, Masoumeh Kourosh Arami, Alireza Komak. Underlying mechanisms of long-term potentiation during the inhibition of the cannabinoid CB1 and GABAB receptors in the dentate gyrus of hippocampus. BMC neuroscience. vol 24. issue 1. 2023-01-12. PMID:36635629. |
in our previous work, we showed that cb1 antagonists increased the population spike (ps) amplitude, field excitatory post-synaptic potential (fepsp), and the ltp induction in the dentate gyrus (dg) of the rat hippocampus while the gaba |
2023-01-12 |
2023-08-14 |
mouse |
| Yuanduo Liu, Hongying Ma, Yangyang Wang, Boxu Ren, Lian Liu, Anbang Sun, Fengru Tan. Neonatal exposure to low-dose X-ray causes behavioral defects and abnormal hippocampal development in mice. IUBMB life. 2023-01-11. PMID:36629313. |
neuroinflammatory cells were observed in the dentate gyrus (dg) and ca3 areas of the hippocampus at pd3 + 1. |
2023-01-11 |
2023-08-14 |
mouse |
| Lívia Neves, Bruno Lobão-Soares, Ana Paula de Castro Araujo, Alan Michel Bezerra Furtunato, Izabela Paiva, Nicholy Souza, Anne Kelly Morais, George Nascimento, Elaine Gavioli, Adriano Bretanha Lopes Tort, Flávio Freitas Barbosa, Hindiael Belchio. Theta and gamma oscillations in the rat hippocampus support the discrimination of object displacement in a recognition memory task. Frontiers in behavioral neuroscience. vol 16. 2023-01-09. PMID:36620858. |
studies on hippocampal lesions in rodents have shown that dentate gyrus (dg) and ca3 are necessary to detect object displacement in memory tasks. |
2023-01-09 |
2023-08-14 |
rat |
| Lívia Neves, Bruno Lobão-Soares, Ana Paula de Castro Araujo, Alan Michel Bezerra Furtunato, Izabela Paiva, Nicholy Souza, Anne Kelly Morais, George Nascimento, Elaine Gavioli, Adriano Bretanha Lopes Tort, Flávio Freitas Barbosa, Hindiael Belchio. Theta and gamma oscillations in the rat hippocampus support the discrimination of object displacement in a recognition memory task. Frontiers in behavioral neuroscience. vol 16. 2023-01-09. PMID:36620858. |
here, we chronically implanted microelectrode arrays in adult male wistar rats to record network oscillations from dg, ca3, and ca1 of the dorsal hippocampus while animals executed an object recognition task of high and low spatial displacement tests (hd: 108 cm, and ld: 54 cm, respectively). |
2023-01-09 |
2023-08-14 |
rat |
| Satoshi Deyama, Shun Aoki, Rinako Sugie, Hayato Fukuda, Satoshi Shuto, Masabumi Minami, Katsuyuki Kaned. Intranasal Administration of Resolvin E1 Produces Antidepressant-Like Effects via BDNF/VEGF-mTORC1 Signaling in the Medial Prefrontal Cortex. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2023-01-09. PMID:36622634. |
additionally, local infusion of rve1 into the medial prefrontal cortex (mpfc) or dorsal hippocampal dentate gyrus (dg) produces antidepressant-like effects. |
2023-01-09 |
2023-08-14 |
mouse |
| Fengmei Wei, Wenhao Li, Bo Ma, Ziqing Yan, Zhi Wang, Lu Zhang, Donghua Xian, Yongqing He, Xiao Deng, Yajie Chen, Zheng Tingjuan, Junfeng Zhang, Yuhong Jin. Local CRF and oxytocin receptors correlate with female experience-driven avoidance change and hippocampal neuronal plasticity. Neurochemistry international. 2023-01-09. PMID:36623734. |
the study explored how neonatal maternal deprivation (md) and post-weaning environmental enrichment (ee) impacted the ca1 and dg's neuronal plasticity in the dorsal hippocampus, and its relationships with passive avoidance, local corticotrophin-releasing factor (crf) levels, and oxytocin receptor (otr) levels in female balb/c mice. |
2023-01-09 |
2023-08-14 |
mouse |
| Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E Flanagan, Rudolph Castellani, Eileen H Bigio, M Marsel Mesulam, Changiz Geula, Tamar Gefe. Differential vulnerability of the dentate gyrus to tauopathies in dementias. Acta neuropathologica communications. vol 11. issue 1. 2023-01-03. PMID:36597124. |
the dentate gyrus (dg), a key hippocampal subregion in memory processing, generally resists phosphorylated tau accumulation in the amnestic dementia of the alzheimer's type due to alzheimer's disease (dat-ad), but less is known about the susceptibility of the dg to other tauopathies. |
2023-01-03 |
2023-08-14 |
human |
| Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E Flanagan, Rudolph Castellani, Eileen H Bigio, M Marsel Mesulam, Changiz Geula, Tamar Gefe. Differential vulnerability of the dentate gyrus to tauopathies in dementias. Acta neuropathologica communications. vol 11. issue 1. 2023-01-03. PMID:36597124. |
we conclude that the dg is differentially vulnerable to pathologic tau accumulation, raising intriguing questions about the structural integrity and functional significance of hippocampal circuits in neurodegenerative dementias. |
2023-01-03 |
2023-08-14 |
human |
| Shirley Jaqueline Szriber, Leonardo Santana Novaes, Nilton Barreto Dos Santos, Carolina Demarchi Munhoz, Deise Carla Almeida Leite-Dellov. Imbalance in the ratio between mineralocorticoid and glucocorticoid receptors and neurodegeneration in the dentate gyrus of aged dogs. Veterinary world. vol 15. issue 11. 2023-01-02. PMID:36590120. |
given the aging changes in dogs' dentate gyrus (dg) and the possible involvement of cortisol receptors in this process, this study aimed to evaluate the expression of mr and gr and neuronal degeneration in this hippocampal region of aged dogs. |
2023-01-02 |
2023-08-14 |
Not clear |
| Qi Liu, Zixu Wang, Jing Cao, Yulan Dong, Yaoxing Che. Insulin ameliorates dim blue light at night-induced apoptosis in hippocampal neurons via the IR/IRS1/AKT/GSK3β/β-catenin signaling pathway. Ecotoxicology and environmental safety. vol 250. 2022-12-31. PMID:36586168. |
consistent with these changes, we also observed that dlan-bl reduced the number of neurons in the ca1, ca3 and dg regions of the hippocampus, up-regulated the mrna expression levels of bax, down-regulated the mrna expression levels of bcl-2, bcl-xl and the protein expression level of pirs1, pakt, pgsk3β, β-catenin in the hippocampus. |
2022-12-31 |
2023-08-14 |
mouse |