| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishid. Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Frontiers in neuroscience. vol 17. 2023-08-14. PMID:37575306. |
the dentate gyrus (dg) of the hippocampus regulates stress-related emotional behaviors and ensures neurogenesis throughout life. |
2023-08-14 |
2023-08-16 |
Not clear |
| Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishid. Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Frontiers in neuroscience. vol 17. 2023-08-14. PMID:37575306. |
nt-3 is expressed in the adult dg of the hippocampus; several chronic stress conditions enhance nt-3 expression in rodents. |
2023-08-14 |
2023-08-16 |
Not clear |
| Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishid. Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Frontiers in neuroscience. vol 17. 2023-08-14. PMID:37575306. |
to directly investigate the impact of nt-3 on dg function, nt-3 was overexpressed in the hippocampal ventral dg by an adeno-associated virus carrying nt-3 (aav-nt-3). |
2023-08-14 |
2023-08-16 |
Not clear |
| Xue Wang, Ya-Jin Shi, Ting-Yuan Niu, Ting-Ting Chen, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats. Neuroscience letters. 2023-08-14. PMID:37579868. |
ppd significantly reduced the cerebral infarction area and the activation of microglia in the cortex and hippocampal dg, ca1, and ca3 area. |
2023-08-14 |
2023-09-07 |
rat |
| Xue Wang, Ya-Jin Shi, Ting-Yuan Niu, Ting-Ting Chen, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats. Neuroscience letters. 2023-08-14. PMID:37579868. |
ppd also significantly alleviated the neurotoxicity by decreasing the aβ and p-tau in hippocampal dg, ca1, and ca3 areas. |
2023-08-14 |
2023-09-07 |
rat |
| Yifan Wang, Qin Hong, Yueyue Xia, Zhao Zhang, Bo We. The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-08-11. PMID:37565374. |
furthermore, in vivo knockdown of kdm7a in dentate gyrus (dg) neuron of mice hippocampus, via adeno-associated virus (aav)-based stereotaxic microinjection, led to a significant decrease of the expression of c-fos, a marker of neuron activity. |
2023-08-11 |
2023-08-16 |
mouse |
| Sophia Vinci-Booher, Margaret L Schlichting, Alison R Preston, Franco Pestill. Development of human hippocampal subfield microstructure and relation to associative inference. Cerebral cortex (New York, N.Y. : 1991). 2023-08-09. PMID:37557916. |
while the subiculum (sub) displayed a linear relationship with age, the dentate gyrus (dg), cornu ammonis field 1 (ca1), and cornu ammonis subfields 2 and 3 (combined; ca2/3) displayed nonlinear trajectories that interacted with sex in ca2/3. |
2023-08-09 |
2023-08-16 |
human |
| Yu-Wen Hung, Guan-Ling Lu, Hwei-Hsien Chen, Hsiu-Hui Tung, Sheau-Ling Le. Gliptins normalize posttraumatic hippocampal neurogenesis and restore cognitive function after controlled cortical impact on sensorimotor cortex. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-08-06. PMID:37544280. |
adult neurogenesis in the hippocampal dentate gyrus (dg) serves critical functions in cognition but can be disrupted by brain injury and insult in serval forms. |
2023-08-06 |
2023-08-14 |
mouse |
| Yu-Wen Hung, Guan-Ling Lu, Hwei-Hsien Chen, Hsiu-Hui Tung, Sheau-Ling Le. Gliptins normalize posttraumatic hippocampal neurogenesis and restore cognitive function after controlled cortical impact on sensorimotor cortex. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-08-06. PMID:37544280. |
dpp-4 inhibitors prevent astrocyte reactivation, normalize the posttraumatic hippocampal neurogenesis and help to maintain normal electrophysiology in the dg with positive behavioral effect in a mouse model. |
2023-08-06 |
2023-08-14 |
mouse |
| Pei-Pei Liu, Shi-Ping Lu, Xiao Li, Gang-Bin Tang, Xiao Liu, Shang-Kun Dai, Lin-Fei Jiao, Xi-Wen Lin, Xing-Guo Li, Baoyang Hu, Jianwei Jiao, Zhao-Qian Teng, Chun-Sheng Han, Chang-Mei Li. Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus. Cell death and differentiation. 2023-08-05. PMID:37543710. |
disruption of arid1a in mouse forebrain significantly decreases neural stem/progenitor cells (nspcs) proliferation and differentiation to neurons within the dentate gyrus (dg), increasing perinatal and postnatal apoptosis, leading to reduced hippocampus size. |
2023-08-05 |
2023-08-14 |
mouse |
| Joshua D Rieskamp, Ileanexis Rosado-Burgos, Jacob E Christofi, Eliza Ansar, Dalia Einstein, Ashley E Walters, Valentina Valentini, John P Bruno, Elizabeth D Kirb. Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal. iScience. vol 26. issue 7. 2023-08-03. PMID:37534178. |
within the adult mammalian dentate gyrus (dg) of the hippocampus, glutamate stimulates neural stem cell (nsc) self-renewing proliferation, providing a link between adult neurogenesis and local circuit activity. |
2023-08-03 |
2023-08-14 |
Not clear |
| Parisa Sadat Panahi, Sogol Esmaili, Mohadeseh Ghalandari-Shamami, Zahra Mousavi, Abbas Haghparas. Similar functional roles of the Orexin-1 and Orexin-2 receptors within the dentate gyrus area of the hippocampus in the stress-induced antinociceptive responses in the acute pain model in the rat. Physiology & behavior. 2023-08-03. PMID:37536620. |
some evidence indicates that the hippocampus's dentate gyrus (dg) potentially modulates pain and stress. |
2023-08-03 |
2023-08-14 |
rat |
| Parisa Sadat Panahi, Sogol Esmaili, Mohadeseh Ghalandari-Shamami, Zahra Mousavi, Abbas Haghparas. Similar functional roles of the Orexin-1 and Orexin-2 receptors within the dentate gyrus area of the hippocampus in the stress-induced antinociceptive responses in the acute pain model in the rat. Physiology & behavior. 2023-08-03. PMID:37536620. |
these findings show that the orexin system in the hippocampal dg region might be partially involved in the sia in acute pain. |
2023-08-03 |
2023-08-14 |
rat |
| Daniel D Callow, Yash Kommula, Craig E L Stark, J Carson Smit. Acute cycling exercise and hippocampal subfield function and microstructure in healthy older adults. Hippocampus. 2023-08-01. PMID:37526119. |
aging is associated with deterioration in dentate gyrus (dg) and ca3, both crucial hippocampal subfields for age susceptible memory processes such as mnemonic discrimination (md). |
2023-08-01 |
2023-08-14 |
human |
| Evanthia A Makrygianni, George P Chrouso. Neural Progenitor Cells and the Hypothalamus. Cells. vol 12. issue 14. 2023-07-29. PMID:37508487. |
in the postnatal/adult brain, npcs are primarily located in the subventricular zone (svz) of the lateral ventricles (lvs) and subgranular zone (sgz) of the hippocampal dentate gyrus (dg). |
2023-07-29 |
2023-08-14 |
Not clear |
| Kelsey D McDermott, M Agustina Frechou, Jake T Jordan, Sunaina S Martin, J Tiago Gonçalve. Delayed formation of neural representations of space in aged mice. Aging cell. 2023-07-26. PMID:37491802. |
the hippocampal dentate gyrus (dg) is important for processing spatial information in the brain and is particularly vulnerable to aging, yet its sparse activity has led to difficulties in assessing changes in this area. |
2023-07-26 |
2023-08-14 |
mouse |
| Liming Dong, Ning Jiang, Jie Bai, Yiman Li, Zhihui Song, Xinmin Liu, Chao Zhan. Neuroprotective Effects of Dammarane Sapogenins Against lipopolysaccharide-induced Cognitive Impairment, Neuroinflammation and Synaptic Dysfunction. Neurochemical research. 2023-07-25. PMID:37490197. |
ds also remarkably inhibited lps-induced neuroinflammation by suppressing microglia overactivation, pro-inflammatory cytok ine release (tnf-α and il-1β) and reducing neuronal loss in the ca1 and dg regions of the hippocampus. |
2023-07-25 |
2023-08-14 |
rat |
| Monica Garcia-Durillo, Bruno G Frenguell. Antagonism of P2X7 receptors enhances lorazepam action in delaying seizure onset in an in vitro model of status epilepticus. Neuropharmacology. 2023-07-17. PMID:37459909. |
this study evaluated the effect of the selective p2x7r antagonist a740003 on acute seizures in the dentate gyrus (dg) of hippocampal brain slices, where p2x7rs are highly expressed, with a view to establishing its potential use as a therapy or adjunct with lorazepam (lzp) in refractory se. |
2023-07-17 |
2023-08-14 |
mouse |
| Monica Garcia-Durillo, Bruno G Frenguell. Antagonism of P2X7 receptors enhances lorazepam action in delaying seizure onset in an in vitro model of status epilepticus. Neuropharmacology. 2023-07-17. PMID:37459909. |
extracellular field excitatory postsynaptic potentials were recorded from the dg of male mouse hippocampal slices when spontaneous seizure-like events (sles) were induced by removing extracellular mg |
2023-07-17 |
2023-08-14 |
mouse |
| Si Sun, Yitong Xu, Ningxi Yu, Meifeng Zhang, Jinghui Wang, Dong Wan, Zhen Tian, Huifeng Zh. Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway. Molecular neurobiology. 2023-07-13. PMID:37439957. |
catalpol remarkably promoted angiogenesis, promoted proliferation and differentiation of neural stem cells (nscs) in the subventricular zone (svz), and prevented neuronal loss and astrocyte activation in the ischemic cortex or hippocampal dentate gyrus (dg) in vivo. |
2023-07-13 |
2023-08-14 |
rat |