| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masoud Mohammadi, Zohreh Tavassoli, Sohrab Anvari, Mohammad Javan, Yaghoub Fathollah. Avoidance and escape conditioning adjust adult neurogenesis to conserve a fit hippocampus in adult male rodents. Journal of neuroscience research. vol 102. issue 1. 2024-01-29. PMID:38284841. |
evaluation of the levels of neurogenesis markers (ki67 and brdu/neun) by immunofluorescence assay in the ddg, idg, and vdg revealed a long-axis disparity in the hippocampal dentate baseline cell proliferation and exposure to the bm and pa task changed the profile of baseline cell proliferation along the dg in both rats and mice. |
2024-01-29 |
2024-01-31 |
mouse |
| Chia-Hsuan Fu, Jason C You, Carrie Mohila, Robert A Rissman, Daniel Yoshor, Angela N Viaene, Jeannie Chi. Hippocampal ΔFosB expression is associated with cognitive impairment in a subgroup of patients with childhood epilepsies. Frontiers in neurology. vol 14. 2024-01-26. PMID:38274865. |
to test whether dg Δfosb expression is indicative of cognitive impairment in epilepsies with different etiologies, we assessed Δfosb expression in surgically-resected hippocampal tissue from 33 patients with childhood epilepsies who had undergone wechsler intelligence scale for children (wisc) testing prior to surgery. |
2024-01-26 |
2024-01-28 |
human |
| Chia-Hsuan Fu, Jason C You, Carrie Mohila, Robert A Rissman, Daniel Yoshor, Angela N Viaene, Jeannie Chi. Hippocampal ΔFosB expression is associated with cognitive impairment in a subgroup of patients with childhood epilepsies. Frontiers in neurology. vol 14. 2024-01-26. PMID:38274865. |
we previously found that, compared with cognitively-intact subjects, the activity-dependent expression of Δfosb in the hippocampal dentate gyrus (dg) was increased in individuals with mild cognitive impairment (mci) and in individuals with ad. |
2024-01-26 |
2024-01-28 |
human |
| Kelli Somelar-Duracz, Monika Jürgenson, Janeli Viil, Alexander Zharkovsky, Külli Jaak. 'Unpredictable chronic mild stress does not exacerbate memory impairment or altered neuronal and glial plasticity in the hippocampus of middle-aged vitamin D deficient mice'. The European journal of neuroscience. 2024-01-25. PMID:38269959. |
while vdd caused cell loss and altered glial response in the dg of the hippocampus, these effects were not exacerbated by ucms and could contribute to mechanisms regulating altered stress response. |
2024-01-25 |
2024-01-27 |
mouse |
| Alexandra Zvozilova, Alexandra Reichova, Mojmir Mach, Jan Bakos, Romana Koprdov. Effect of a New Substance with Pyridoindole Structure on Adult Neurogenesis, Shape of Neurons, and Behavioral Outcomes in a Chronic Mild Stress Model in Rats. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38255918. |
administration of sme1ec2m3 significantly increased sox2-positive cells in the hippocampal dentate gyrus (dg) in cms compared to control animals. |
2024-01-23 |
2024-01-25 |
rat |
| Isaac Vingan, Victoria Sook Keng Tung, Shwetha Phatarpekar, A Iván Hernández, Oleg V Evgrafov, Juan Marcos Alarco. Spatially Resolved Transcriptomic Signatures of Hippocampal Subregions and bioRxiv : the preprint server for biology. 2024-01-23. PMID:38260257. |
we found that training induced differentially expressed genes (degs) in the ca1 and ca3 hippocampal subregions were enriched with genes involved in synaptic transmission and synaptic plasticity, while degs in the dentate gyrus (dg) were enriched with genes involved in energy balance and ribosomal function. |
2024-01-23 |
2024-01-25 |
Not clear |
| Alfredo Zuniga, Jiawei Han, Isaac Miller-Crews, Laura A Agee, Hans A Hofmann, Michael R Dre. Extinction Training Suppresses Activity of Fear Memory Ensembles Across the Hippocampus and Alters Transcriptomes of Fear-Encoding Cells. bioRxiv : the preprint server for biology. 2024-01-23. PMID:38260411. |
contextual fear conditioning has been shown to activate a set of "fear ensemble" cells in the hippocampal dentate gyrus (dg) whose reactivation is necessary and sufficient for expression of contextual fear. |
2024-01-23 |
2024-01-25 |
Not clear |
| Ning Jiang, Yiwen Zhang, Caihong Yao, Fang Chen, Yupei Liu, Yuzhen Chen, Yan Wang, Muhammad Iqbal Choudhary, Xinmin Li. Hemerocallis citrina Baroni ameliorates chronic sleep deprivation-induced cognitive deficits and depressive-like behaviours in mice. Life sciences in space research. vol 40. 2024-01-20. PMID:38245346. |
furthermore, hce suppressed sd-induced microglial activation in the prefrontal cortex (pfc) and the ca1 and dentate gyrus (dg) regions of the hippocampus. |
2024-01-20 |
2024-01-23 |
mouse |
| Hamideh Mostafaee, Faezeh Idoon, Mina Mohasel-Roodi, Fatemeh Alipour, Nasim Lotfi, Akram Sadegh. The Effects of Induced Type I Diabetes on Developmental Regulation of GDNF, NRTN, and NCAM proteins in the Dentate Gyrus of male Rat offspring. Journal of chemical neuroanatomy. 2024-01-14. PMID:38219812. |
therefore, this study aimed to investigate the impacts of the mentioned neurotrophic factors in the hippocampal dentate gyrus (dg) of rat offspring born to diabetic mothers. |
2024-01-14 |
2024-01-17 |
rat |
| Ji-Wei Tan, Juan Ji An, Hannah Deane, Haifei Xu, Guey-Ying Liao, Baoji X. Neurotrophin-3 from the dentate gyrus supports postsynaptic sites of mossy fiber-CA3 synapses and hippocampus-dependent cognitive functions. Molecular psychiatry. 2024-01-11. PMID:38212372. |
at the center of the hippocampal tri-synaptic loop are synapses formed between mossy fiber (mf) terminals from granule cells in the dentate gyrus (dg) and proximal dendrites of ca3 pyramidal neurons. |
2024-01-11 |
2024-01-14 |
mouse |
| Marijke Vergaelen, Simona Manzella, Kristl Vonck, Erine Craey, Jeroen Spanoghe, Mathieu Sprengers, Evelien Carrette, Wytse Jan Wadman, Jean Delbeke, Paul Boon, Lars Emil Larsen, Robrecht Raed. Increased Dentate Gyrus Excitability in the Intrahippocampal Kainic Acid Mouse Model for Temporal Lobe Epilepsy. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203829. |
we recorded field postsynaptic potentials (fpsps) after electrical stimulation in the ca1 region and in the dentate gyrus (dg) of hippocampal slices of ihka and healthy mice using a multielectrode array (mea). |
2024-01-11 |
2024-01-13 |
mouse |
| Marijke Vergaelen, Simona Manzella, Kristl Vonck, Erine Craey, Jeroen Spanoghe, Mathieu Sprengers, Evelien Carrette, Wytse Jan Wadman, Jean Delbeke, Paul Boon, Lars Emil Larsen, Robrecht Raed. Increased Dentate Gyrus Excitability in the Intrahippocampal Kainic Acid Mouse Model for Temporal Lobe Epilepsy. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203829. |
these results point to increased neuronal excitability in the dg but not in the ca1 region of the hippocampus of ihka mice. |
2024-01-11 |
2024-01-13 |
mouse |
| Marijke Vergaelen, Simona Manzella, Kristl Vonck, Erine Craey, Jeroen Spanoghe, Mathieu Sprengers, Evelien Carrette, Wytse Jan Wadman, Jean Delbeke, Paul Boon, Lars Emil Larsen, Robrecht Raed. Increased Dentate Gyrus Excitability in the Intrahippocampal Kainic Acid Mouse Model for Temporal Lobe Epilepsy. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203829. |
this method, in which the excitability of hippocampal slices from ihka mice is investigated using a mea, can now be further explored as a potential new model to screen for new interventions that can restore dg function and potentially lead to novel therapies for mtle. |
2024-01-11 |
2024-01-13 |
mouse |
| He Huang, Ning Wang, Jia-Tao Lin, Yong-Kang Qiu, Wei-Feng Wu, Qiang Liu, Chen Chen, Hai-Bi Wang, Yan-Ping Liu, Wei Dong, Jie Wan, Hui Zheng, Cheng-Hua Zhou, Yu-Qing W. Repeated Ketamine Anesthesia during the Neonatal Period Impairs Hippocampal Neurogenesis and Long-Term Neurocognitive Function by Inhibiting Mfn2-Mediated Mitochondrial Fusion in Neural Stem Cells. Molecular neurobiology. 2024-01-10. PMID:38200350. |
for the interventional study, lentivirus (lv) overexpressing mfn2 (lv-mfn2) or control lv vehicle was microinjected into the hippocampal dentate gyrus (dg) 4 days before ketamine administration. |
2024-01-10 |
2024-01-13 |
rat |
| He Huang, Ning Wang, Jia-Tao Lin, Yong-Kang Qiu, Wei-Feng Wu, Qiang Liu, Chen Chen, Hai-Bi Wang, Yan-Ping Liu, Wei Dong, Jie Wan, Hui Zheng, Cheng-Hua Zhou, Yu-Qing W. Repeated Ketamine Anesthesia during the Neonatal Period Impairs Hippocampal Neurogenesis and Long-Term Neurocognitive Function by Inhibiting Mfn2-Mediated Mitochondrial Fusion in Neural Stem Cells. Molecular neurobiology. 2024-01-10. PMID:38200350. |
preconditioning with lv-mfn2 improved long-term cognitive dysfunction after repeated neonatal ketamine exposure by reversing the inhibitory effect of ketamine on synaptic plasticity in the hippocampal dg. |
2024-01-10 |
2024-01-13 |
rat |
| Shahab Ghaderi, Parsa Gholipour, Alireza Komaki, Siamak Shahidi, Faezeh Seif, Mohammad Bahrami-Tapehebur, Iraj Salehi, Mohammad Zarei, Abdolrahman Sarihi, Masome Rashn. Underlying mechanisms behind the neuroprotective effect of vanillic acid against diabetes-associated cognitive decline: An in vivo study in a rat model. Phytotherapy research : PTR. 2024-01-08. PMID:38185917. |
long-term potentiation (ltp) was induced at hippocampal dentate gyrus (dg) synapses in response to high-frequency stimulation (hfs) applied to the perforant pathway (pp) to evaluate synaptic plasticity. |
2024-01-08 |
2024-01-10 |
rat |
| Chi Xu, Jiayu Ye, Yanting Sun, Xiujian Sun, Jing-Gen Li. The Antidepressant Effect of Magnolol on Depression-Like Behavior of CORT-Treated Mice. Journal of molecular neuroscience : MN. vol 74. issue 1. 2024-01-06. PMID:38183534. |
prevented cort-induced depression-like behavior and reduced cort-induced dynorphin (dyn a) elevation in the hippocampal ventral dg. |
2024-01-06 |
2024-01-09 |
mouse |
| Chi Xu, Jiayu Ye, Yanting Sun, Xiujian Sun, Jing-Gen Li. The Antidepressant Effect of Magnolol on Depression-Like Behavior of CORT-Treated Mice. Journal of molecular neuroscience : MN. vol 74. issue 1. 2024-01-06. PMID:38183534. |
the present study demonstrated that magnolol could ameliorate cort-induced depression-like behaviors, by modulating the dyn a/kor system in the ventral dg of the hippocampus. |
2024-01-06 |
2024-01-09 |
mouse |
| Nicholas Chalmers, Evangelia Masouti, Ruth Beckervordersandfort. Astrocytes in the adult dentate gyrus-balance between adult and developmental tasks. Molecular psychiatry. 2024-01-04. PMID:38177351. |
in this review, we focus on astrocytes of the hippocampal dentate gyrus (dg), and discuss specific features of the astrocytic compartment that may allow the execution of both tasks. |
2024-01-04 |
2024-01-07 |
Not clear |
| Nicholas Chalmers, Evangelia Masouti, Ruth Beckervordersandfort. Astrocytes in the adult dentate gyrus-balance between adult and developmental tasks. Molecular psychiatry. 2024-01-04. PMID:38177351. |
the diversity and dynamic of astrocytes in the adult dg implicate a vital contribution to hippocampal plasticity and represent an interesting model to uncover mechanisms how astrocytes simultaneously fulfill developmental and adult tasks. |
2024-01-04 |
2024-01-07 |
Not clear |