| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuhui Deng, Xin Liang, Yue Li, Lin Jiang, Jin Wang, Jing Tang, Jing Li, Yuhan Xie, Kai Xiao, Peilin Zhu, Yijing Guo, Yanmin Luo, Yong Tan. PGC-1α in the hippocampus mediates depressive-like and stress-coping behaviours and regulates excitatory synapses in the dentate gyrus in mice. Neuropharmacology. 2024-03-16. PMID:38492883. |
moreover, the downregulation of hippocampal pgc-1α expression resulted in a decrease in the number of excitatory synapses in the dg and in the protein expression of ucp2 in the hippocampus. |
2024-03-16 |
2024-03-19 |
mouse |
| Yuhui Deng, Xin Liang, Yue Li, Lin Jiang, Jin Wang, Jing Tang, Jing Li, Yuhan Xie, Kai Xiao, Peilin Zhu, Yijing Guo, Yanmin Luo, Yong Tan. PGC-1α in the hippocampus mediates depressive-like and stress-coping behaviours and regulates excitatory synapses in the dentate gyrus in mice. Neuropharmacology. 2024-03-16. PMID:38492883. |
this suggests that hippocampal pgc-1α is involved in regulating depressive-like and stress-coping behaviours and modulating the number of excitatory synapses in the dg. |
2024-03-16 |
2024-03-19 |
mouse |
| Saiying Wang, Haijun Zhang, Rui Liu, Peijun Han, Qi Yang, Caiyan Cheng, Yue Chen, Zheng Rong, Chang Su, Fei Li, Gaofei Wei, Minggao Zhao, Le Yan. Influenza A Virus PB1-F2 Induces Affective Disorder by Interfering Synaptic Plasticity in Hippocampal Dentate Gyrus. Molecular neurobiology. 2024-03-15. PMID:38488981. |
in this study, we constructed and injected pb1-f2 into the hippocampal dentate gyrus (dg), a region closely associated with newborn neurons and neural development, to evaluate its influence on negative affective behaviors and learning performance in mice. |
2024-03-15 |
2024-03-18 |
mouse |
| Qian Tang, Ryota Ojiro, Shunsuke Ozawa, Xinyu Zou, Junta Nakahara, Tomohiro Nakao, Mihoko Koyanagi, Meilan Jin, Toshinori Yoshida, Makoto Shibutan. DNA methylation-altered genes in the rat hippocampal neurogenic niche after continuous exposure to amorphous curcumin. Journal of chemical neuroanatomy. 2024-03-15. PMID:38490283. |
rat offspring who are exposed to an amorphous formula of curcumin (cur) from the embryonic stage have anti-anxiety-like behaviors, enhanced fear extinction learning, and increased synaptic plasticity in the hippocampal dentate gyrus (dg). |
2024-03-15 |
2024-03-18 |
rat |
| Poornima D E Weerasinghe-Mudiyanselage, Sohi Kang, Joong-Sun Kim, Sung-Ho Kim, Hongbing Wang, Taekyun Shin, Changjong Moo. Changes in structural plasticity of hippocampal neurons in an animal model of multiple sclerosis. Zoological research. vol 45. issue 2. 2024-03-14. PMID:38485508. |
dendritic complexity was largely affected in the cornu ammonis 1 (ca1) and ca3 apical and dentate gyrus (dg) subregions of the hippocampus during the chronic phase, while this effect was only noted in the ca1 apical subregion in the early phase. |
2024-03-14 |
2024-03-17 |
mouse |
| Joana Martins-Macedo, Bruna Araújo, Sandra I Anjo, Tiago Silveira-Rosa, Patrícia Patrício, Nuno Dinis Alves, Joana M Silva, Fábio G Teixeira, Bruno Manadas, Ana J Rodrigues, Angelo C Lepore, António J Salgado, Eduardo D Gomes, Luísa Pint. Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation. Molecular psychiatry. 2024-03-07. PMID:38454085. |
to examine the role of newly formed glia, we transplanted glial restricted precursors (grps) into the adult hippocampal dentate gyrus (dg), or injected their secreted factors (secretome), into a previously validated transgenic gfap-tk rat line, in which cytogenesis is transiently compromised. |
2024-03-07 |
2024-03-10 |
rat |
| Pierre Mortessagne, Estelle Cartier, Maddalena Balia, Murielle Fèvre, Fiona Corailler, Cyril Herry, Djoher Nora Abrous, Arne Battefeld, Emilie Pacar. Genetic labeling of embryonically-born dentate granule neurons in young mice using the Penk Scientific reports. vol 14. issue 1. 2024-02-29. PMID:38424161. |
genetic labeling of embryonically-born dentate granule neurons in young mice using the penk the dentate gyrus (dg) of the hippocampus is a mosaic of dentate granule neurons (dgns) accumulated throughout life. |
2024-02-29 |
2024-03-03 |
mouse |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
since glutamatergic transmission and nmda receptor neural pathways in hippocampal dentate gyrus (dg) are essential in the learning and memory, we aimed to investigate glutamate (glu) and nmda receptor signaling of dg in spatial learning and memory in diet-induced obesity (dio) rats. |
2024-02-28 |
2024-03-01 |
rat |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
in conclusion, the enhancement of glu-nmda receptor transmission in the hippocampal dg contributes to the impairment of spatial learning and memory in dio rats, maybe via the modulation of camkii-creb-bdnf signaling pathway. |
2024-02-28 |
2024-03-01 |
rat |
| Allegra Kawles, Rachel Keszycki, Grace Minogue, Antonia Zouridakis, Ivan Ayala, Nathan Gill, Alyssa Macomber, Vivienne Lubbat, Christina Coventry, Emily Rogalski, Sandra Weintraub, Qinwen Mao, Margaret E Flanagan, Hui Zhang, Rudolph Castellani, Eileen H Bigio, M-Marsel Mesulam, Changiz Geula, Tamar Gefe. Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias. Acta neuropathologica communications. vol 12. issue 1. 2024-02-23. PMID:38389095. |
paraffin-embedded sections were stained immunohistochemically with at8 to visualize pick bodies, and unbiased stereological analysis was performed in up to six regions bilaterally [middle frontal gyrus (mfg), superior temporal gyrus (stg), inferior parietal lobule (ipl), anterior temporal lobe (atl), dentate gyrus (dg) and ca1 of the hippocampus], and unilateral occipital cortex (occ). |
2024-02-23 |
2024-02-25 |
Not clear |
| Erik H Middlebrooks, Vivek Gupta, Amit K Agarwal, Brin E Freund, Steven A Messina, William O Tatum, David S Sabsevitz, Anteneh M Feyissa, Seyed M Mirsattari, Fernando N Galan, Alfredo Quinones-Hinojosa, Sanjeet S Grewal, John V Murra. Radiologic Classification of Hippocampal Sclerosis in Epilepsy. AJNR. American journal of neuroradiology. 2024-02-21. PMID:38383054. |
this framework will not only benefit current clinical evaluations, but also enhance future studies involving high-resolution mri in temporal lobe epilepsy.abbreviations: ca = cornu ammonis; dg = dentate gyrus; hs = hippocampal sclerosis; ilae = international league against epilepsy; srlm = strata radiatum, lacunosum, and moleculare layers; tle = temporal lobe epilepsy. |
2024-02-21 |
2024-02-24 |
Not clear |
| Farzaneh Nazari-Serenjeh, Mehdi Sadeghi, Ronak Azizbeigi, Hadi Semizeh, Sajad Mazaheri, Amir Haghparast, Abbas Haghparas. Blocking the dopaminergic receptors within the hippocampal dentate gyrus reduced analgesic responses induced by restraint stress in the formalin test. Behavioural brain research. 2024-02-18. PMID:38368953. |
previous studies have shown that various receptors, including dopamine receptors, are expressed in the hippocampal dentate gyrus (dg). |
2024-02-18 |
2024-02-21 |
rat |
| Qiang Liu, Xing Luo, Ziqi Liang, Dezhe Qin, Mingyue Xu, Min Wang, Weixiang Gu. Coordination between circadian neural circuit and intracellular molecular clock ensures rhythmic activation of adult neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 8. 2024-02-12. PMID:38346182. |
the circadian clock throughout the day organizes the activity of neural stem cells (nscs) in the dentate gyrus (dg) of adult hippocampus temporally. |
2024-02-12 |
2024-02-15 |
Not clear |
| Laura Bellingacci, Jacopo Canonichesi, Miriam Sciaccaluga, Alfredo Megaro, Petra Mazzocchetti, Michela Di Mauro, Cinzia Costa, Massimiliano Di Filippo, Vito Enrico Pettorossi, Alessandro Tozz. Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338656. |
electrophysiological recordings were performed to measure dentate gyrus (dg) ltp in rat hippocampal slices. |
2024-02-10 |
2024-02-12 |
rat |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Long-term calorie restriction prevented memory impairment in middle-aged male mice and increased a marker of dna oxidative stress in hippocampal dentate gyrus. Neurobiology of learning and memory. 2024-02-09. PMID:38336097. |
in addition, immunohistochemistry targetingΔfosb (neuronal activity),brain-derived neurotrophic factor (bdnf) and thedna oxidative damage (8ohdg) in hippocampal subfields ca1, ca2, ca3, and dentate gyrus (dg), and in basolateral amygdala and striatum were performed. |
2024-02-09 |
2024-02-12 |
mouse |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Long-term calorie restriction prevented memory impairment in middle-aged male mice and increased a marker of dna oxidative stress in hippocampal dentate gyrus. Neurobiology of learning and memory. 2024-02-09. PMID:38336097. |
our results showed that long-term cr prevented short-term memory impairment related to aging and increased 8ohdg in hippocampal dg. |
2024-02-09 |
2024-02-12 |
mouse |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Long-term calorie restriction prevented memory impairment in middle-aged male mice and increased a marker of dna oxidative stress in hippocampal dentate gyrus. Neurobiology of learning and memory. 2024-02-09. PMID:38336097. |
in conclusion, while the effects of long-term cr on anxiety-type behavior were inconclusive, it mitigated the memory deficit related to aging, which was accompanied by an increase in hippocampal 8ohdg in dg. |
2024-02-09 |
2024-02-12 |
mouse |
| Qian-Qian Wei, Yong-Yu Yin, Yong-Xing Qiao, Han Ni, Shuo-Yu Han, Yishan Yao, Yun-Feng Li, Li-Ming Zhang, Junxu L. Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) via regulating the synaptic plasticity in hippocampus. European journal of pharmacology. 2024-02-08. PMID:38331342. |
in addition, yl-ipa08 also enhanced the dendritic complexity and dendritic spine density of hippocampal dentate gyrus (dg) granule neurons. |
2024-02-08 |
2024-02-11 |
mouse |
| Naoki Yamamoto, Jun Yokose, Kritika Ramesh, Takashi Kitamura, Sachie K Ogaw. Outer layer of Vb neurons in medial entorhinal cortex project to hippocampal dentate gyrus in mice. Molecular brain. vol 17. issue 1. 2024-02-05. PMID:38317261. |
in this study, using a molecular marker for vb and retrograde tracers, we identified that the outer layer of vb neurons in the medial ec (mec) directly project to both dorsal and ventral hippocampal dentate gyrus (dg), with a significant preference for the ventral dg. |
2024-02-05 |
2024-02-09 |
mouse |
| Masoud Mohammadi, Zohreh Tavassoli, Sohrab Anvari, Mohammad Javan, Yaghoub Fathollah. Avoidance and escape conditioning adjust adult neurogenesis to conserve a fit hippocampus in adult male rodents. Journal of neuroscience research. vol 102. issue 1. 2024-01-29. PMID:38284841. |
recording field potentials at performant pathway (pp)-hippocampal dentate gyrus (dg) synapses in transverse slices from the dorsal (d), intermediate (i), and ventral (v) hippocampus showed differences in paired-pulse responses and long-term potentiation in rats. |
2024-01-29 |
2024-01-31 |
mouse |