| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oier Pastor-Alonso, Anum Syeda Zahra, Bente Kaske, Fernando García-Moreno, Felix Tetzlaff, Enno Bockelmann, Vanessa Grunwald, Soraya Martín-Suárez, Kristoffer Riecken, Otto Wilhelm Witte, Juan Manuel Encinas, Anja Urbac. Generation of adult hippocampal neural stem cells occurs in the early postnatal dentate gyrus and depends on cyclin D2. The EMBO journal. 2024-01-04. PMID:38177500. |
lifelong hippocampal neurogenesis is maintained by a pool of multipotent adult neural stem cells (anscs) residing in the subgranular zone of the dentate gyrus (dg). |
2024-01-04 |
2024-01-07 |
mouse |
| Rong-Xin Zou, Xiaozhen Gu, Chenqing Huang, Hui-Li Wang, Xiang-Tao Che. Chronic Pb exposure impairs learning and memory abilities by inhibiting excitatory projection neuro-circuit of the hippocampus in mice. Toxicology. 2023-12-31. PMID:38160928. |
in conclusion, our data indicated that pb significantly impaired the excitatory connections from ec to the hippocampus (ca1 and dg), providing a novel neuro-circuitry basis for pb neurotoxicity. |
2023-12-31 |
2024-01-05 |
mouse |
| Kim Ngan Hoang, Yushan Huang, Esther Fujiwara, Nikolai Malykhi. Effects of healthy aging and mnemonic strategies on verbal memory performance across the adult lifespan: Mediating role of posterior hippocampus. Hippocampus. 2023-12-25. PMID:38145465. |
in this study, we aimed to understand the contributions of hippocampal anteroposterior subregions (head, body, tail) and subfields (cornu ammonis 1-3 [ca1-3], dentate gyrus [dg], and subiculum [sub]) and encoding strategies to the age-related verbal memory decline. |
2023-12-25 |
2023-12-27 |
human |
| Kim Ngan Hoang, Yushan Huang, Esther Fujiwara, Nikolai Malykhi. Effects of healthy aging and mnemonic strategies on verbal memory performance across the adult lifespan: Mediating role of posterior hippocampus. Hippocampus. 2023-12-25. PMID:38145465. |
while total ca1-3 and dg volumes did not show direct or indirect effects on verbal memory, exploratory analyses with dg and ca1-3 volumes within the hippocampal body subregion suggested an indirect effect of age-related volumetric reduction on verbal memory performance through semantic clustering. |
2023-12-25 |
2023-12-27 |
human |
| b' Andrijana Stanisavljevi\\xc4\\x87 Ili\\xc4\\x87, Sne\\xc5\\xbeana \\xc4\\x90or\\xc4\\x91evi\\xc4\\x87, Drago\\xc5\\xa1 Inta, Stefan Borgwardt, Dragana Filipovi\\xc4\\x8. Olanzapine Effects on Parvalbumin/GAD67 Cell Numbers in Layers/Subregions of Dorsal Hippocampus of Chronically Socially Isolated Rats. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139008.' |
we determined the effect of olz on pv-positive (+) and glutamate decarboxylase 67 (gad67) + cell numbers in the layers of dorsal hippocampus (dhipp) cornu ammonis (ca1-ca3) and dentate gyrus (dg) subregions in rats exposed to chronic social isolation (csis), which is an animal model of depression. |
2023-12-23 |
2023-12-25 |
rat |
| Jasmin A Strickland, Joseph M Austen, Rolf Sprengel, David J Sanderso. Knockout of NMDARs in CA1 and dentate gyrus fails to impair temporal control of conditioned behavior in mice. Hippocampus. 2023-12-23. PMID:38140716. |
we tested the prediction that hippocampal nmda receptors are required for learning about time by testing mice that lack postembryonal nmdars in the ca1 and dentate gyrus (dg) hippocampal subfields on three different appetitive temporal learning procedures. |
2023-12-23 |
2023-12-25 |
mouse |
| Hirofumi Hirakawa, Takeshi Terao, Koji Hatano, Masanao Shirahama, Tsuyoshi Kugimiya, Kentaro Kohno, Hiroyuki Matsuta, Tsuyoshi Shimomura, Minoru Fujik. Increased volume of the left hippocampal dentate gyrus after 4 weeks of bright light exposure in patients with mood disorders: a randomized controlled study. Translational psychiatry. vol 13. issue 1. 2023-12-15. PMID:38102115. |
bright light exposure (bl) induces neurogenesis in the rat hippocampal dentate gyrus (dg). |
2023-12-15 |
2023-12-18 |
human |
| Su-Hyun Kim, Chong-Hyun Ki. Neuronal IGF-1 overexpression restores hippocampal newborn cell survival and recent CFC memory consolidation in Ca Brain research. 2023-12-14. PMID:38097125. |
neuronal igf-1 overexpression restores hippocampal newborn cell survival and recent cfc memory consolidation in ca insulin-like growth factor-1 (igf-1) exogenously supplied in the brain was shown to enhance the survival of hippocampal dentate gyrus (dg) newborn cells and some cognitive functions of mice. |
2023-12-14 |
2023-12-17 |
mouse |
| Kaige Liu, Yue Qu, Bozhi Li, Ningxi Zeng, Gaolei Yao, Xiaofeng Wu, Hanfang Xu, Can Yan, Lili W. GRP94 in cerebrospinal fluid may contribute to a potential biomarker of depression: Based on proteomics. Journal of psychiatric research. vol 169. 2023-12-11. PMID:38081093. |
flx significantly increased neuronal numbers in dentate gyrus (dg) and ca3 regions of hippocampus. |
2023-12-11 |
2023-12-17 |
rat |
| Michelle C Gulfo, Joseph J Lebowitz, Czarina Ramos, Dong-Woo Hwang, Kaoutsar Nasrallah, Pablo E Castill. Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 50. 2023-12-08. PMID:38064513. |
hilar mossy cells (mcs) are principal excitatory neurons of the dentate gyrus (dg) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety and epilepsy. |
2023-12-08 |
2023-12-17 |
Not clear |
| Yu Dong, Zihan Lu, Tiantian Gao, Zhifeng Wei, Zhijie Ou, Zheng Shi, Jie She. A polypeptide derived from pilose antler ameliorates CUMS-induced depression-like behavior by SENP2-PLCβ4 signaling axis. European journal of pharmacology. 2023-12-06. PMID:38056617. |
neurogenesis in the dentate gyrus (dg) region of hippocampus was observed by immunofluorescence. |
2023-12-06 |
2023-12-10 |
Not clear |
| Kaitlyn E Dorst, Ryan A Senne, Anh H Diep, Antje R de Boer, Rebecca L Suthard, Heloise Leblanc, Evan A Ruesch, Angela Y Pyo, Sara Skelton, Lucas C Carstensen, Samantha Malmberg, Olivia P McKissick, John H Bladon, Steve Ramire. Hippocampal engrams generate variable behavioral responses and brain-wide network states. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-12-05. PMID:38050098. |
to address this, we optogenetically reactivated a fear engram in the dentate gyrus (dg) subregion of the hippocampus across three distinct contexts in male mice. |
2023-12-05 |
2023-12-10 |
mouse |
| Yanyi Ding, Long Li, Sinuo Wang, Yajun Cao, Minguang Yang, Yaling Dai, Huawei Lin, Jianhong Li, Yulu Liu, Zhifu Wang, Weilin Liu, Jing Ta. Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model. Biological research. vol 56. issue 1. 2023-12-02. PMID:38041203. |
impaired pattern separation occurs in the early stage of alzheimer's disease (ad), and hippocampal dentate gyrus (dg) neurogenesis participates in pattern separation. |
2023-12-02 |
2023-12-10 |
mouse |
| Anbiao Wu, Jiyan Zhan. Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis. Journal of neuroinflammation. vol 20. issue 1. 2023-11-28. PMID:38012702. |
neuroinflammation has been reported to be involved in mdd through distinct neurobiological mechanisms, among which the dysregulation of neurogenesis in the dentate gyrus (dg) of the hippocampus (hpc) is receiving increasing attention. |
2023-11-28 |
2023-11-29 |
Not clear |
| Anbiao Wu, Jiyan Zhan. Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis. Journal of neuroinflammation. vol 20. issue 1. 2023-11-28. PMID:38012702. |
the dg of the hippocampus is one of two niches for neurogenesis in the adult mammalian brain, and neurotrophic factors are fundamental regulators of this neurogenesis process. |
2023-11-28 |
2023-11-29 |
Not clear |
| Yan Cao, Pan Liu, Hongfei Bian, Sixuan Jin, Jiaqi Liu, Ning Yu, Huan Cui, Fengrun Sun, Xiaojing Qian, Wenying Qiu, Chao M. Reduced neurogenesis in human hippocampus with Alzheimer's disease. Brain pathology (Zurich, Switzerland). 2023-11-27. PMID:38012054. |
in this study, we observed a significant presence of neurogenic cells in the hippocampus's dentate gyrus (dg) region in 30 individuals, including 14 individuals diagnosed with ad-related neuropathological changes and the remaining 16 individuals without any neurological diseases. |
2023-11-27 |
2023-11-29 |
human |
| Matin Baghani, Arad Bolouri-Roudsari, Reyhaneh Askari, Abbas Haghparas. Orexin receptors in the hippocampal dentate gyrus modulated the restraint stress-induced analgesia in the animal model of chronic pain. Behavioural brain research. vol 459. 2023-11-25. PMID:37995966. |
since orexin neuropeptides are involved in pain modulation, and orexin neurons, primarily located in the lateral hypothalamus (lh), project to various hippocampal regions, such as the dentate gyrus (dg), the current study aimed to examine the role of orexin receptors within the dg region in the restraint sia in the animal model of chronic pain. |
2023-11-25 |
2023-11-28 |
rat |
| Dore Loef, Indira Tendolkar, Philip F P van Eijndhoven, Jeroen J M Hoozemans, Mardien L Oudega, Annemieke J M Rozemuller, Paul J Lucassen, Annemiek Dols, Anke A Dijkstr. Electroconvulsive therapy is associated with increased immunoreactivity of neuroplasticity markers in the hippocampus of depressed patients. Translational psychiatry. vol 13. issue 1. 2023-11-20. PMID:37981649. |
in rodents, electroconvulsive shocks increase proliferation and the expression of plasticity markers in the hippocampal dentate gyrus (dg), suggesting increased neurogenesis. |
2023-11-20 |
2023-11-29 |
human |
| Aiai Dong, Zhen Gao, Haijun Wang, Ronglin Wu, Weifeng Wang, Xiaofei Jin, Yufang Ji, Faming Yang, Tao Zhu, Ziwen Jiang, Yongrong Xu, Jilong Guo, Laixi J. Acupuncture Alleviates Chronic Ischemic White Matter Injury in SHR Rats via JNK-NMDAR Circuit. Molecular neurobiology. 2023-11-17. PMID:37976026. |
myelin density was detected by luxol fast blue (lfb) staining, also axon arrangement, myelin integrity, and thickness of neurons were detected by electron microscopy; neuronal morphology and the number of nissl bodies in the hippocampus were detected by nissl staining, dendritic spine density changes were detected by golgi staining, and jnk, nmdar1, and n-methyl-d-receptor 2b (nmdar2b) in dg, ca3 region of hippocampus were detected by immunohistochemistry, protein expression of p-jnk/jnk, p-nmdar1/nmdar1, nmdar2b, gsk3β protein expression in the fimbria of hippocampus was detected by western blot. |
2023-11-17 |
2023-11-20 |
rat |
| Abigail C Toltin, Abdelmadjid Belkadi, Laura M Gamba, Muhammad M Hossai. The Preventive Effects of Salubrinal against Pyrethroid-Induced Disruption of Adult Hippocampal Neurogenesis in Mice. International journal of molecular sciences. vol 24. issue 21. 2023-11-14. PMID:37958604. |
salubrinal prevented hippocampal er stress, as indicated by decreased levels of c/ebp-homologous protein (chop) and transcription factor 4 (atf4) and attenuated deltamethrin-induced reductions in brdu-, ki-67-, and dcx-positive cells in the dentate gyrus (dg) of the hippocampus. |
2023-11-14 |
2023-11-20 |
mouse |