| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
it has been shown that pattern separation specifically relies on the hippocampal dentate gyrus (dg), whereas pattern completion is performed within ca3 networks. |
2019-06-21 |
2023-08-13 |
human |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
in anti-leucine-rich, glioma-inactivated 1 (lgi1) encephalitis it has been shown in animal models and human imaging studies that hippocampal dg and ca3 are preferentially involved in the pathophysiology process. |
2019-06-21 |
2023-08-13 |
human |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
structural sequelae were determined by hippocampal subfield volumetry for the dg, ca1, and ca2/3. |
2019-06-21 |
2023-08-13 |
human |
| Alfonso Diaz, Samuel Treviño, Rubén Vázquez-Roque, Berenice Venegas, Blanca Espinosa, Gonzalo Flores, Juan Manuel Fernández-G, Luis F Montaño, Jorge Guevar. The aminoestrogen prolame increases recognition memory and hippocampal neuronal spine density in aged mice. Synapse (New York, N.Y.). vol 71. issue 10. 2019-06-18. PMID:28545157. |
our aim was to evaluate the effect of prolame on motor and cognitive processes, as well as its influence on the dendritic morphology of neurons at the ca1, ca3, and granule cells of the dentate gyrus (dg) regions of hippocampus (hp), and medium spiny neurons of the nucleus accumbens (nacc) of aged mice. |
2019-06-18 |
2023-08-13 |
mouse |
| Junhua Li, Minyan Guo, Yafang Liu, Guiyun Wu, Liping Miao, Jing Zhang, Zhiyi Zuo, Yujuan L. Both GSK-3β/CRMP2 and CDK5/CRMP2 pathways participate in the protection of dexmedetomidine against propofol-induced learning and memory impairment in neonatal rats. Toxicological sciences : an official journal of the Society of Toxicology. 2019-06-12. PMID:31187143. |
propofol induced apoptosis in the hippocampal neurons and astrocytes, inhibited neuronal proliferation in the dg region, down-regulated the level of γ-aminobutyric acid (gaba) and glutamate in the hippocampus, and impaired long-term cognitive function. |
2019-06-12 |
2023-08-13 |
rat |
| Tirzah Kreisel, Brachi Wolf, Eli Keshet, Tamar Lich. Unique role for dentate gyrus microglia in neuroblast survival and in VEGF-induced activation. Glia. vol 67. issue 4. 2019-06-11. PMID:30453385. |
to examine whether mg residing in the hippocampal neurogenic zone are inherently different from mg residing elsewhere in the hippocampus, we compared growth factor responsiveness of dg mg with that of ca1 mg. |
2019-06-11 |
2023-08-13 |
Not clear |
| Tirzah Kreisel, Brachi Wolf, Eli Keshet, Tamar Lich. Unique role for dentate gyrus microglia in neuroblast survival and in VEGF-induced activation. Glia. vol 67. issue 4. 2019-06-11. PMID:30453385. |
taken together, findings uncover inherent unique properties of dg mg of supporting both basal- and vegf-induced adult hippocampal neurogenesis. |
2019-06-11 |
2023-08-13 |
Not clear |
| Jianqin Yuan, Qi Li, Ruiyan Niu, Jundong Wan. Fluoride exposure decreased learning ability and the expressions of the insulin receptor in male mouse hippocampus and olfactory bulb. Chemosphere. vol 224. 2019-06-10. PMID:30818196. |
irs mainly distributed in the olfactory nerve layer of the outermost layer of the ob, and most distributed in the hippocampal cornu ammon 3 (ca3) region, followed by the dentate gyrus (dg) and cornu ammon 1 (ca1) regions. |
2019-06-10 |
2023-08-13 |
mouse |
| Priyanka Rao-Ruiz, Jonathan J Couey, Ivo M Marcelo, Christian G Bouwkamp, Denise E Slump, Mariana R Matos, Rolinka J van der Loo, Gabriela J Martins, Mirjam van den Hout, Wilfred F van IJcken, Rui M Costa, Michel C van den Oever, Steven A Kushne. Engram-specific transcriptome profiling of contextual memory consolidation. Nature communications. vol 10. issue 1. 2019-06-06. PMID:31110186. |
sparse populations of neurons in the dentate gyrus (dg) of the hippocampus are causally implicated in the encoding of contextual fear memories. |
2019-06-06 |
2023-08-13 |
Not clear |
| Shigeyoshi Saito, Kazuhiko Sawada, Ichio Aok. Prenatal Irradiation-Induced Hippocampal Abnormalities in Rats Evaluated Using Manganese-Enhanced MRI. Frontiers in neural circuits. vol 12. 2019-06-03. PMID:30618648. |
furthermore, glial components consisted largely by astrocytes and minor by microglia were densely distributed in the dg rather than in other hippocampal regions, and their density radiation-exposed rats. |
2019-06-03 |
2023-08-13 |
rat |
| Tomasz Stępień, Sylwia Tarka, Dominik Chutorański, Paulina Felczak, Albert Acewicz, Teresa Wierzba-Bobrowic. Neurogenesis in adult human brain after hemorrhage and ischemic stroke. Folia neuropathologica. vol 56. issue 4. 2019-05-30. PMID:30786666. |
in the adult human brain, two neurogenic regions, the hippocampal dentate gyrus (dg) and the subventricular zone (svz) of lateral ventricles, have been identified. |
2019-05-30 |
2023-08-13 |
human |
| Dong-Hee Choi, In-Ae Choi, Cheol Soon Lee, Ji Hee Yun, Jongmin Le. The Role of NOX4 in Parkinson's Disease with Dementia. International journal of molecular sciences. vol 20. issue 3. 2019-05-29. PMID:30736297. |
in the 6-hydroxydopamine (6-ohda)-injected mouse model, cognitive and motor function, and the levels of α-syn, aβ, and oligomer a11 after inhibition of nox4 expression in the hippocampal dentate gyrus (dg) were measured by the morris water maze, novel object recognition, rotation, and rotarod tests, as well as immunoblotting and immunohistochemistry. |
2019-05-29 |
2023-08-13 |
mouse |
| Dong-Hee Choi, In-Ae Choi, Cheol Soon Lee, Ji Hee Yun, Jongmin Le. The Role of NOX4 in Parkinson's Disease with Dementia. International journal of molecular sciences. vol 20. issue 3. 2019-05-29. PMID:30736297. |
6-ohda dose-dependent cognitive impairment was observed, and the increased cognitive impairment, aβ expression, and oligomer a11 production in 6-ohda-treated mice were suppressed by nox4 knockdown in the hippocampal dg. |
2019-05-29 |
2023-08-13 |
mouse |
| Dong-Hee Choi, In-Ae Choi, Cheol Soon Lee, Ji Hee Yun, Jongmin Le. The Role of NOX4 in Parkinson's Disease with Dementia. International journal of molecular sciences. vol 20. issue 3. 2019-05-29. PMID:30736297. |
our results suggest that increased expression of nox4 in the hippocampal dg in the 6-ohda-treated mouse induces aβ expression and oligomer a11 production, thereby reducing cognitive function. |
2019-05-29 |
2023-08-13 |
mouse |
| Nannan Guo, Marta E Soden, Charlotte Herber, Michael TaeWoo Kim, Antoine Besnard, Paoyan Lin, Xiang Ma, Constance L Cepko, Larry S Zweifel, Amar Saha. Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. Nature medicine. vol 24. issue 4. 2019-05-20. PMID:29529016. |
in the hippocampal dentate gyrus (dg), memories are thought to be encoded by so-called 'engram-bearing' dentate granule cells (edgcs). |
2019-05-20 |
2023-08-13 |
mouse |
| S Ray, M J Corenblum, A Anandhan, A Reed, F O Ortiz, D D Zhang, C A Barnes, L Madhava. A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells. Cell transplantation. vol 27. issue 4. 2019-05-17. PMID:29871525. |
since nrf2 is a major transcription factor at the heart of cellular redox regulation and homeostasis, the current study investigates the role that it may play in the aging of nspcs that reside within the other major mammalian germinal niche located in the subgranular zone (sgz) of the dentate gyrus (dg) of the hippocampus. |
2019-05-17 |
2023-08-13 |
mouse |
| S Ray, M J Corenblum, A Anandhan, A Reed, F O Ortiz, D D Zhang, C A Barnes, L Madhava. A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells. Cell transplantation. vol 27. issue 4. 2019-05-17. PMID:29871525. |
furthermore, the enrichment of the hippocampal environment via the transplantation of nrf2-overexpressing nspcs was able to mitigate the age-related decline in dg stem cell regeneration during the critical middle-age period, and significantly improved pattern separation abilities. |
2019-05-17 |
2023-08-13 |
mouse |
| Takuya Sasaki, Verónica C Piatti, Ernie Hwaun, Siavash Ahmadi, John E Lisman, Stefan Leutgeb, Jill K Leutge. Dentate network activity is necessary for spatial working memory by supporting CA3 sharp-wave ripple generation and prospective firing of CA3 neurons. Nature neuroscience. vol 21. issue 2. 2019-05-16. PMID:29335604. |
complex spatial working memory tasks have been shown to require both hippocampal sharp-wave ripple (swr) activity and dentate gyrus (dg) neuronal activity. |
2019-05-16 |
2023-08-13 |
rat |
| Lin Jiang, Jing Ma, Yi Zhang, Chun-Ni Zhou, Lei Zhang, Feng-Lei Chao, Lin-Mu Chen, Rong Jiang, Hong Wu, Yong Tan. Effect of running exercise on the number of the neurons in the hippocampus of young transgenic APP/PS1 mice. Brain research. vol 1692. 2019-05-08. PMID:29715445. |
the stereological methods were used to quantitatively evaluate the volume of the hippocampus, ca1/2, ca3 and the dentate gyrus (dg) and count the number of the neurons in ca1/2, ca3 and dg. |
2019-05-08 |
2023-08-13 |
mouse |
| Lin Jiang, Jing Ma, Yi Zhang, Chun-Ni Zhou, Lei Zhang, Feng-Lei Chao, Lin-Mu Chen, Rong Jiang, Hong Wu, Yong Tan. Effect of running exercise on the number of the neurons in the hippocampus of young transgenic APP/PS1 mice. Brain research. vol 1692. 2019-05-08. PMID:29715445. |
more importantly, 4-month running effectively increased the volumes of the hippocampus, ca1/2, ca3 and dg and increased the number of neurons in ca1/2, ca3 and dg in young app/ps1 mice. |
2019-05-08 |
2023-08-13 |
mouse |