| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M K Chawla, V L Sutherland, K Olson, B L McNaughton, C A Barne. Behavior-driven arc expression is reduced in all ventral hippocampal subfields compared to CA1, CA3, and dentate gyrus in rat dorsal hippocampus. Hippocampus. vol 28. issue 2. 2019-02-13. PMID:29232477. |
we report here, that arc is expressed in a greater proportion of cells in dorsal ca1, ca3, and dentate gyrus (dg), following spatial behavioral experiences compared to ventral hippocampal subregions (dorsal ca1 = 33%; ventral ca1 = 13%; dorsal ca3 = 23%; ventral ca3 = 8%; and dorsal dg = 2.5%; ventral dg = 1.2%). |
2019-02-13 |
2023-08-13 |
rat |
| Raymond P Kesne. An analysis of dentate gyrus function (an update). Behavioural brain research. vol 354. 2019-02-08. PMID:28756212. |
dysfunction of the dorsal dg can be shown to mediate mnemonic processing of spatially based information including a) the operation of conjunctive encoding of multiple sensory inputs to determine spatial representations, b) pattern separation based on reducing interference between similar spatial locations and spatial contexts for horizontal distance between objects, vertical distance for height of objects, slope or angle of motor movements, c) importance of spatial context in object recognition and processing of shades of grey associated with the walls of the box d) temporal integration in the creation of remote memory based in part on dg neurogenesis and function of the ca3 subregion of the hippocampus. |
2019-02-08 |
2023-08-13 |
rat |
| Xiangchang Zeng, Lulu Chen, Luping Zhou, Wei Luo, Kai Hu, Dongsheng Ouyan. [Expression and spatial distribution of P2X7 receptor in pilocarpine-induced epileptic rat hippocampus]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 42. issue 9. 2019-02-08. PMID:28989142. |
the expression pattern of p2x7 receptor in hippocampal dg and ca3 area was consistent with protein expression, but its expression in hippocampal ca1 area was not significantly changed after se.
conclusion: the expression of p2x7 receptor in post-se hippocampus is in a time-dependent manner and spatial specificity. |
2019-02-08 |
2023-08-13 |
rat |
| Hua Tian, Louis J Sparvero, Andrew A Amoscato, Anna Bloom, Hülya Bayır, Valerian E Kagan, Nicholas Winogra. Gas Cluster Ion Beam Time-of-Flight Secondary Ion Mass Spectrometry High-Resolution Imaging of Cardiolipin Speciation in the Brain: Identification of Molecular Losses after Traumatic Injury. Analytical chemistry. vol 89. issue 8. 2019-02-07. PMID:28306235. |
high-resolution images of naive and injured brain tissue facilitated the comparison of cl species across three multicell layers in the ca1, ca3, and dg regions of the hippocampus. |
2019-02-07 |
2023-08-13 |
Not clear |
| Iraj Salehi, Alireza Komaki, Seyed Asaad Karimi, Abdolrahman Sarihi, Mohammad Zare. Effect of garlic powder on hippocampal long-term potentiation in rats fed high fat diet: an in vivo study. Metabolic brain disease. vol 33. issue 3. 2019-02-05. PMID:29294234. |
the objective of this study was to determine the relation between the chronic consumption of garlic powder in combination with high-fat diet (hfd) on long term potentiation (ltp) in the dentate gyrus (dg) of rat hippocampus. |
2019-02-05 |
2023-08-13 |
rat |
| Iraj Salehi, Alireza Komaki, Seyed Asaad Karimi, Abdolrahman Sarihi, Mohammad Zare. Effect of garlic powder on hippocampal long-term potentiation in rats fed high fat diet: an in vivo study. Metabolic brain disease. vol 33. issue 3. 2019-02-05. PMID:29294234. |
it was suggested that the garlic powder administration could attenuate the deteriorating effect of hfd on in vivo hippocampal ltp in the granular cells of the dg. |
2019-02-05 |
2023-08-13 |
rat |
| Victor Silva da Fonsêca, André R da Silva Colla, Cristine de Paula Nascimento-Castro, Evelini Plácido, Julia Macedo Rosa, Marcelo Farina, Joana Gil-Mohapel, Ana Lúcia S Rodrigues, Patricia S Brocard. Brain-Derived Neurotrophic Factor Prevents Depressive-Like Behaviors in Early-Symptomatic YAC128 Huntington's Disease Mice. Molecular neurobiology. vol 55. issue 9. 2019-02-04. PMID:29388082. |
however, bdnf treatment only increased cell proliferation and neuronal differentiation in the hippocampal dentate gyrus (dg) of wild-type (wt) mice, without altering these parameters in their yac128 counterparts. |
2019-02-04 |
2023-08-13 |
mouse |
| Victor Silva da Fonsêca, André R da Silva Colla, Cristine de Paula Nascimento-Castro, Evelini Plácido, Julia Macedo Rosa, Marcelo Farina, Joana Gil-Mohapel, Ana Lúcia S Rodrigues, Patricia S Brocard. Brain-Derived Neurotrophic Factor Prevents Depressive-Like Behaviors in Early-Symptomatic YAC128 Huntington's Disease Mice. Molecular neurobiology. vol 55. issue 9. 2019-02-04. PMID:29388082. |
moreover, bdnf treatment did not cause an increase in the number of dendritic branches in the hippocampal dg when compared with animals treated with vehicle. |
2019-02-04 |
2023-08-13 |
mouse |
| Saba Shahin, Somanshu Banerjee, Vivek Swarup, Surya Pal Singh, Chandra Mohini Chaturved. From the Cover: 2.45-GHz Microwave Radiation Impairs Hippocampal Learning and Spatial Memory: Involvement of Local Stress Mechanism-Induced Suppression of iGluR/ERK/CREB Signaling. Toxicological sciences : an official journal of the Society of Toxicology. vol 161. issue 2. 2019-01-30. PMID:29069439. |
ca1, ca2, ca3, and dg through immunohistochemistry/immunofluorescence and alterations in the expression of hippocampal glucocorticoid receptor, crh-receptor 1 (crh-r1), camp-response element-binding (creb), and phosphorylated-creb (p-creb) through western blot analysis. |
2019-01-30 |
2023-08-13 |
mouse |
| Yuka Mimura-Yamamoto, Hiroshi Shinohara, Taichi Kashiwagi, Toru Sato, Seiji Shioda, Tatsunori Sek. Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development. Scientific reports. vol 7. issue 1. 2019-01-23. PMID:28717168. |
in the developing hippocampus, granule cell progenitors (gcps) arising in the ventricular zone (vz) migrate to the subpial region, and form the granule cell layer (gcl) of the dentate gyrus (dg). |
2019-01-23 |
2023-08-13 |
Not clear |
| Kazuya Suwabe, Kazuki Hyodo, Kyeongho Byun, Genta Ochi, Takemune Fukuie, Takeshi Shimizu, Morimasa Kato, Michael A Yassa, Hideaki Soy. Aerobic fitness associates with mnemonic discrimination as a mediator of physical activity effects: evidence for memory flexibility in young adults. Scientific reports. vol 7. issue 1. 2019-01-16. PMID:28698596. |
a potential mechanism for this effect is exercise-enhanced hippocampal plasticity, particularly in the dentate gyrus (dg). |
2019-01-16 |
2023-08-13 |
Not clear |
| Kazuya Suwabe, Kazuki Hyodo, Kyeongho Byun, Genta Ochi, Takemune Fukuie, Takeshi Shimizu, Morimasa Kato, Michael A Yassa, Hideaki Soy. Aerobic fitness associates with mnemonic discrimination as a mediator of physical activity effects: evidence for memory flexibility in young adults. Scientific reports. vol 7. issue 1. 2019-01-16. PMID:28698596. |
within hippocampal memory formation, the dg plays a crucial role in pattern separation, which is the ability to discriminate among similar experiences. |
2019-01-16 |
2023-08-13 |
Not clear |
| Michael G Ruscio, S Bradley King, Serena-Kaye Kinley-Cooper, Greer McKendric. Social environment affects central distribution of estrogen receptor-α in Peromyscus californicus. General and comparative endocrinology. vol 269. 2019-01-14. PMID:30145237. |
females housed for 24 days had significantly greater erα-ir in the dentate gyrus of the hippocampus (dg) when compared with females housed for 4 days. |
2019-01-14 |
2023-08-13 |
mouse |
| Aruna Vashishta, Lukasz P Slomnicki, Maciej Pietrzak, Scott C Smith, Murali Kolikonda, Shivani P Naik, Rosanna Parlato, Michal Hetma. RNA Polymerase 1 Is Transiently Regulated by Seizures and Plays a Role in a Pharmacological Kindling Model of Epilepsy. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29546592. |
however, after selectively deleting the essential pol1 co-activator, transcription initiation factor-1a (tif1a/rrn3) from excitatory neurons, ptz kindling was impaired while dg total ribosome content was moderately reduced and no major neurodegeneration was observed throughout the hippocampus. |
2018-12-17 |
2023-08-13 |
mouse |
| Helen E Scharfma. Advances in understanding hilar mossy cells of the dentate gyrus. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29222692. |
hilar mossy cells (mcs) of the dentate gyrus (dg) distinguish the dg from other hippocampal subfields (ca1-3) because there are two glutamatergic cell types in the dg rather than one. |
2018-12-11 |
2023-08-13 |
mouse |
| Prashant K Srivastava, Paolo Roncon, Katarzyna Lukasiuk, Jan A Gorter, Eleonora Aronica, Asla Pitkänen, Enrico Petretto, Michael R Johnson, Michele Simonat. Meta-Analysis of MicroRNAs Dysregulated in the Hippocampal Dentate Gyrus of Animal Models of Epilepsy. eNeuro. vol 4. issue 6. 2018-12-11. PMID:29291240. |
here, we undertook a meta-analysis of changes in mirna expression in the hippocampal dentate gyrus (dg) following an epileptogenic insult in three epilepsy models. |
2018-12-11 |
2023-08-13 |
Not clear |
| Yusuke Takai, Misato Kawai, Tadashi Ogo, Takashi Ichinose, Shigeki Furuya, Nozomu Takaki, Yukihiro Tone, Hiroshi Udo, Mitsuhiro Furuse, Shinobu Yasu. Early-life Photoperiod Influences Depression-like Behavior, Prepulse Inhibition of the Acoustic Startle Response, and Hippocampal Astrogenesis in Mice. Neuroscience. vol 374. 2018-11-20. PMID:29406270. |
at 4 weeks of age, there were less 5-bromo-2'-deoxyuridine (brdu)-positive cells in the dentate gyrus (dg) of the hippocampus of mice born under sd when compared with mice born under ld. |
2018-11-20 |
2023-08-13 |
mouse |
| Hiroshi Tawarayama, Hirohisa Yamada, Ruhul Amin, Yuiko Morita-Fujimura, Helen M Cooper, Yohei Shinmyo, Masakado Kawata, Shuntaro Ikawa, Hideaki Tanak. Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis. Scientific reports. vol 8. issue 1. 2018-11-19. PMID:29339781. |
hippocampal neurogenesis in the dentate gyrus (dg) is controlled by diffusible molecules that modulate neurogenic processes, including cell proliferation, differentiation and survival. |
2018-11-19 |
2023-08-13 |
Not clear |
| Hiroshi Tawarayama, Hirohisa Yamada, Ruhul Amin, Yuiko Morita-Fujimura, Helen M Cooper, Yohei Shinmyo, Masakado Kawata, Shuntaro Ikawa, Hideaki Tanak. Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis. Scientific reports. vol 8. issue 1. 2018-11-19. PMID:29339781. |
to elucidate the mechanisms underlying hippocampal neurogenesis, we investigated the function of draxin, originally identified as a neural chemorepellent, in the regulation of neuronal survival in the dg. |
2018-11-19 |
2023-08-13 |
Not clear |
| Ukpong B Eyo, Ashley Bispo, Junting Liu, Sruchika Sabu, Rong Wu, Victoria L DiBona, Jiaying Zheng, Madhuvika Murugan, Huaye Zhang, Yamei Tang, Long-Jun W. The GluN2A Subunit Regulates Neuronal NMDA receptor-Induced Microglia-Neuron Physical Interactions. Scientific reports. vol 8. issue 1. 2018-11-19. PMID:29339791. |
finally, consistent with differentially expressed glun2a subunits in the ca1 and dg areas of the hippocampus, these interactions could not be elicited in the dg despite robust microglial chemotactic capabilities. |
2018-11-19 |
2023-08-13 |
Not clear |