| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aruna Vashishta, Lukasz P Slomnicki, Maciej Pietrzak, Scott C Smith, Murali Kolikonda, Shivani P Naik, Rosanna Parlato, Michal Hetma. RNA Polymerase 1 Is Transiently Regulated by Seizures and Plays a Role in a Pharmacological Kindling Model of Epilepsy. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29546592. |
however, after selectively deleting the essential pol1 co-activator, transcription initiation factor-1a (tif1a/rrn3) from excitatory neurons, ptz kindling was impaired while dg total ribosome content was moderately reduced and no major neurodegeneration was observed throughout the hippocampus. |
2018-12-17 |
2023-08-13 |
mouse |
| Helen E Scharfma. Advances in understanding hilar mossy cells of the dentate gyrus. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29222692. |
hilar mossy cells (mcs) of the dentate gyrus (dg) distinguish the dg from other hippocampal subfields (ca1-3) because there are two glutamatergic cell types in the dg rather than one. |
2018-12-11 |
2023-08-13 |
mouse |
| Prashant K Srivastava, Paolo Roncon, Katarzyna Lukasiuk, Jan A Gorter, Eleonora Aronica, Asla Pitkänen, Enrico Petretto, Michael R Johnson, Michele Simonat. Meta-Analysis of MicroRNAs Dysregulated in the Hippocampal Dentate Gyrus of Animal Models of Epilepsy. eNeuro. vol 4. issue 6. 2018-12-11. PMID:29291240. |
here, we undertook a meta-analysis of changes in mirna expression in the hippocampal dentate gyrus (dg) following an epileptogenic insult in three epilepsy models. |
2018-12-11 |
2023-08-13 |
Not clear |
| Yusuke Takai, Misato Kawai, Tadashi Ogo, Takashi Ichinose, Shigeki Furuya, Nozomu Takaki, Yukihiro Tone, Hiroshi Udo, Mitsuhiro Furuse, Shinobu Yasu. Early-life Photoperiod Influences Depression-like Behavior, Prepulse Inhibition of the Acoustic Startle Response, and Hippocampal Astrogenesis in Mice. Neuroscience. vol 374. 2018-11-20. PMID:29406270. |
at 4 weeks of age, there were less 5-bromo-2'-deoxyuridine (brdu)-positive cells in the dentate gyrus (dg) of the hippocampus of mice born under sd when compared with mice born under ld. |
2018-11-20 |
2023-08-13 |
mouse |
| Hiroshi Tawarayama, Hirohisa Yamada, Ruhul Amin, Yuiko Morita-Fujimura, Helen M Cooper, Yohei Shinmyo, Masakado Kawata, Shuntaro Ikawa, Hideaki Tanak. Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis. Scientific reports. vol 8. issue 1. 2018-11-19. PMID:29339781. |
hippocampal neurogenesis in the dentate gyrus (dg) is controlled by diffusible molecules that modulate neurogenic processes, including cell proliferation, differentiation and survival. |
2018-11-19 |
2023-08-13 |
Not clear |
| Hiroshi Tawarayama, Hirohisa Yamada, Ruhul Amin, Yuiko Morita-Fujimura, Helen M Cooper, Yohei Shinmyo, Masakado Kawata, Shuntaro Ikawa, Hideaki Tanak. Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis. Scientific reports. vol 8. issue 1. 2018-11-19. PMID:29339781. |
to elucidate the mechanisms underlying hippocampal neurogenesis, we investigated the function of draxin, originally identified as a neural chemorepellent, in the regulation of neuronal survival in the dg. |
2018-11-19 |
2023-08-13 |
Not clear |
| Ukpong B Eyo, Ashley Bispo, Junting Liu, Sruchika Sabu, Rong Wu, Victoria L DiBona, Jiaying Zheng, Madhuvika Murugan, Huaye Zhang, Yamei Tang, Long-Jun W. The GluN2A Subunit Regulates Neuronal NMDA receptor-Induced Microglia-Neuron Physical Interactions. Scientific reports. vol 8. issue 1. 2018-11-19. PMID:29339791. |
finally, consistent with differentially expressed glun2a subunits in the ca1 and dg areas of the hippocampus, these interactions could not be elicited in the dg despite robust microglial chemotactic capabilities. |
2018-11-19 |
2023-08-13 |
Not clear |
| Bart C Jongbloets, Suzanne Lemstra, Roberta Schellino, Mark H Broekhoven, Jyoti Parkash, Anita J C G M Hellemons, Tianyi Mao, Paolo Giacobini, Henriette van Praag, Silvia De Marchis, Geert M J Ramakers, R Jeroen Pasterkam. Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors. Nature communications. vol 8. 2018-11-16. PMID:28281529. |
here we show that sema7a utilizes different cell surface receptors to control the proliferation and differentiation of neural progenitors in the adult hippocampal dentate gyrus (dg), one of the select regions of the mature brain where neurogenesis occurs. |
2018-11-16 |
2023-08-13 |
mouse |
| Kazuya Suwabe, Kyeongho Byun, Kazuki Hyodo, Zachariah M Reagh, Jared M Roberts, Akira Matsushita, Kousaku Saotome, Genta Ochi, Takemune Fukuie, Kenji Suzuki, Yoshiyuki Sankai, Michael A Yassa, Hideaki Soy. Rapid stimulation of human dentate gyrus function with acute mild exercise. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 41. 2018-11-15. PMID:30249651. |
our prior work using a special treadmill running model in animals has shown that stress-free mild exercise increases hippocampal neuronal activity and promotes adult neurogenesis in the dentate gyrus (dg) of the hippocampus, improving spatial memory performance. |
2018-11-15 |
2023-08-13 |
human |
| Kazuya Suwabe, Kyeongho Byun, Kazuki Hyodo, Zachariah M Reagh, Jared M Roberts, Akira Matsushita, Kousaku Saotome, Genta Ochi, Takemune Fukuie, Kenji Suzuki, Yoshiyuki Sankai, Michael A Yassa, Hideaki Soy. Rapid stimulation of human dentate gyrus function with acute mild exercise. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 41. 2018-11-15. PMID:30249651. |
however, the rapid modification, from mild exercise, on hippocampal memory function and the exact mechanisms for these changes, in particular the impact on pattern separation acting in the dg and ca3 regions, are yet to be elucidated. |
2018-11-15 |
2023-08-13 |
human |
| Zuojun Tian, Qiuge Zhao, Sangita Biswas, Wenbin Den. Methods of reactivation and reprogramming of neural stem cells for neural repair. Methods (San Diego, Calif.). vol 133. 2018-11-09. PMID:28864354. |
adult neurogenesis presents in particular regions in mammal brain, known as neurogenic niches such as the dental gyrus (dg) in hippocampus and the subventricular zone (svz), within which adult nscs usually stay for long periods out of the cell cycle, in g0. |
2018-11-09 |
2023-08-13 |
Not clear |
| Valentina Ghisays, Elizabeth T Nguyen, Joshua Streicher, Nicholas A Pease, Maureen Fitzgerald, Christina M Estrada, Ana Franco-Villanueva, Lisa Privette Vinnedge, Matia B Solomo. Neuroanatomical Distribution of DEK Protein in Corticolimbic Circuits Associated with Learning and Memory in Adult Male and Female Mice. Neuroscience. vol 371. 2018-11-09. PMID:29175155. |
dek was also abundant in all amygdalar subdivisions (basolateral, central and medial) and in the hippocampus including the ca1, ca2, ca3, dentate gyrus (dg), ventral subiculum and entorhinal cortex. |
2018-11-09 |
2023-08-13 |
mouse |
| Kun Zhang, Yu-Jiao Li, Dan Feng, Peng Zhang, Ya-Tao Wang, Xiang Li, Shui-Bing Liu, Yu-Mei Wu, Ming-Gao Zha. Imbalance between TNFα and progranulin contributes to memory impairment and anxiety in sleep-deprived mice. Scientific reports. vol 7. 2018-11-08. PMID:28300056. |
pgrn treatment also restored dendritic spine density in the hippocampus ca1 region and neurogenesis in hippocampus dentate gyrus (dg). |
2018-11-08 |
2023-08-13 |
mouse |
| Jing Xu, Yasushi Yabuki, Mengze Yu, Kohji Fukunag. T-type calcium channel enhancer SAK3 produces anti-depressant-like effects by promoting adult hippocampal neurogenesis in olfactory bulbectomized mice. Journal of pharmacological sciences. vol 137. issue 4. 2018-11-06. PMID:30196018. |
the impaired adult neurogenesis in the hippocampal dentate gyrus (dg) that occurred 4 weeks after obx administration was significantly restored by chronic sak3 administration (0.5 or 1.0 mg/kg, p.o.). |
2018-11-06 |
2023-08-13 |
mouse |
| J Chwiej, M Palczynska, A Skoczen, K Janeczko, J Cieslak, R Simon, Z Setkowic. Elemental changes of hippocampal formation occurring during postnatal brain development. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 49. 2018-10-09. PMID:29895356. |
the increased fe areal density was found in all examined hippocampal areas whilst zn was elevated in ca3, dg and h. in order to follow the dynamics of age-dependent elemental changes, the statistical significance of differences in their accumulation between subsequent moments of time was examined. |
2018-10-09 |
2023-08-13 |
rat |
| Martina Kristofova, Yogesh D Aher, Marija Ilic, Bojana Radoman, Predrag Kalaba, Vladimir Dragacevic, Nilima Y Aher, Johann Leban, Volker Korz, Lisa Zanon, Winfried Neuhaus, Marcus Wieder, Thierry Langer, Ernst Urban, Harald H Sitte, Harald Hoeger, Gert Lubec, Jana Aradsk. A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval. Behavioural brain research. vol 343. 2018-09-18. PMID:29410048. |
since dat blockers can be considered as indirect dopamine receptor agonists, western blotting was used to quantify protein levels of dopamine receptors d1r, d2r and d5r and dat in the synaptosomal fraction of hippocampal subregions ca1, ca3 and dentate gyrus (dg). |
2018-09-18 |
2023-08-13 |
human |
| Yulong Cai, Xiaotong Tang, Xi Chen, Xin Li, Ying Wang, Xiaohang Bao, Lian Wang, Dayu Sun, Jinghui Zhao, Yan Xing, Margaret Warner, Haiwei Xu, Jan-Åke Gustafsson, Xiaotang Fa. Liver X receptor β regulates the development of the dentate gyrus and autistic-like behavior in the mouse. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 12. 2018-09-18. PMID:29507213. |
the dentate gyrus (dg) of the hippocampus is a laminated brain region in which neurogenesis begins during early embryonic development and continues until adulthood. |
2018-09-18 |
2023-08-13 |
mouse |
| Yu Zhou, Chaolin Ma, Bao-Ming Li, Chong Su. Polygala japonica Houtt. reverses depression-like behavior and restores reduced hippocampal neurogenesis in chronic stress mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 99. 2018-09-17. PMID:29710497. |
we also found that pj had no significant effect on cell proliferation and neuronal differentiation in dentate gyrus (dg) of the hippocampus, but it inhibited the apoptosis of the newborn neurons by activation of bcl-2 and phopho-erk1/2 and increased the number of the newborn neurons. |
2018-09-17 |
2023-08-13 |
mouse |
| Tyler C Alexander, Christy M Simecka, Frederico Kiffer, Thomas Groves, Julie Anderson, Hannah Carr, Jing Wang, Gwendolyn Carter, Antiño R Alle. Changes in cognition and dendritic complexity following intrathecal methotrexate and cytarabine treatment in a juvenile murine model. Behavioural brain research. vol 346. 2018-09-11. PMID:29229546. |
mtx/arac treatment significantly compromised the dendritic architecture and reduced mushroom spine density in the dorsal ganglion (dg), ca1, and ca3 areas of the hippocampus. |
2018-09-11 |
2023-08-13 |
mouse |
| Meng Zhang, Dong Chen, Jing Xia, Wenqi Han, Xiekui Cui, Nils Neuenkirchen, Gretchen Hermes, Nenad Sestan, Haifan Li. Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins. Genes & development. vol 31. issue 13. 2018-08-21. PMID:28794184. |
consistently, the mutant dg neurospheres generated fewer nscs with defects in proliferation, survival, and differentiation, supporting a major role of pum1 and pum2 in hippocampal neurogenesis and function. |
2018-08-21 |
2023-08-13 |
mouse |