| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lin Jiang, Jing Ma, Yi Zhang, Chun-Ni Zhou, Lei Zhang, Feng-Lei Chao, Lin-Mu Chen, Rong Jiang, Hong Wu, Yong Tan. Effect of running exercise on the number of the neurons in the hippocampus of young transgenic APP/PS1 mice. Brain research. vol 1692. 2019-05-08. PMID:29715445. |
the present results suggested that 4-month running has significant beneficial effects on the spatial learning and memory capacities of young app/ps1 mice and could delay the progress of atrophy of hippocampus and the neuron death in ca1/2, ca3 and dg in young app/ps1 mice. |
2019-05-08 |
2023-08-13 |
mouse |
| F Scharkowski, Michael Frotscher, David Lutz, Martin Korte, Kristin Michaelsen-Preuss. Altered Connectivity and Synapse Maturation of the Hippocampal Mossy Fiber Pathway in a Mouse Model of the Fragile X Syndrome. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 3. 2019-05-07. PMID:28077511. |
surprisingly, one of the most complex hippocampal synapses connecting the dentate gyrus (dg) to ca3 pyramidal neurons has not been analyzed in fxs yet. |
2019-05-07 |
2023-08-13 |
mouse |
| N C Woodward, A Haghani, R G Johnson, T M Hsu, A Saffari, C Sioutas, S E Kanoski, C E Finch, T E Morga. Prenatal and early life exposure to air pollution induced hippocampal vascular leakage and impaired neurogenesis in association with behavioral deficits. Translational psychiatry. vol 8. issue 1. 2019-05-06. PMID:30498214. |
at age 5 months, exposed male rats had 70% fewer newly generated neurons in the dentate gyrus (dg) of the hippocampus. |
2019-05-06 |
2023-08-13 |
human |
| Tania Campos-Ordonez, David Zarate-Lopez, Nereida Ibarra-Castaneda, Jonathan Buritica, Oscar Gonzalez-Pere. Cyclohexane Inhalation Produces Long-Lasting Alterations in the Hippocampal Integrity and Reward-Seeking Behavior in the Adult Mouse. Cellular and molecular neurobiology. vol 39. issue 3. 2019-05-06. PMID:30771197. |
this study aimed to establish the behavioral changes and the pathological alterations that occur in the cornu ammonis 3 (ca3) and dentate gyrus (dg) after a long-lasting exposure to chx. |
2019-05-06 |
2023-08-13 |
mouse |
| Tania Campos-Ordonez, David Zarate-Lopez, Nereida Ibarra-Castaneda, Jonathan Buritica, Oscar Gonzalez-Pere. Cyclohexane Inhalation Produces Long-Lasting Alterations in the Hippocampal Integrity and Reward-Seeking Behavior in the Adult Mouse. Cellular and molecular neurobiology. vol 39. issue 3. 2019-05-06. PMID:30771197. |
we exposed cd1 mice to a recreational-like dose of chx (~ 30,000 ppm) for 30 days and explored its consequences in motor skills, reward-seeking behavior, and the ca3 and dg hippocampal subfields. |
2019-05-06 |
2023-08-13 |
mouse |
| Dwi Liliek Kusindarta, Hevi Wihadmadyatami, Arvendi R Jadi, Srikanth Karnati, Guenter Lochnit, Puspa Hening, Aris Haryanto, Made B Auriva, Medania Purwaningru. Ethanolic extract Ocimum sanctum. Enhances cognitive ability from young adulthood to middle aged mediated by increasing choline acetyl transferase activity in rat model. Research in veterinary science. vol 118. 2019-05-02. PMID:29729605. |
further, nissl staining was performed to analyze hippocampus formation in dentate gyrus (dg), cornu ammonis 1 (ca1), cornu ammonis 3 (ca3). |
2019-05-02 |
2023-08-13 |
rat |
| Dong Sun, Xiang-Dong Sun, Lu Zhao, Dae-Hoon Lee, Jin-Xia Hu, Fu-Lei Tang, Jin-Xiu Pan, Lin Mei, Xiao-Juan Zhu, Wen-Cheng Xion. Neogenin, a regulator of adult hippocampal neurogenesis, prevents depressive-like behavior. Cell death & disease. vol 9. issue 1. 2019-04-30. PMID:29311593. |
adult neurogenesis in hippocampal dentate gyrus (dg) is a complex, but precisely controlled process. |
2019-04-30 |
2023-08-13 |
mouse |
| Shitong Xiang, Yu Zhou, Jingxuan Fu, Tao Zhan. rTMS pre-treatment effectively protects against cognitive and synaptic plasticity impairments induced by simulated microgravity in mice. Behavioural brain research. vol 359. 2019-04-23. PMID:30292903. |
in the hippocampus dg and ca1 regions, dendritic spine density was measured using golgi-cox staining. |
2019-04-23 |
2023-08-13 |
mouse |
| Irena Majkutewicz, Ewelina Kurowska, Magdalena Podlacha, Dorota Myślińska, Beata Grembecka, Jan Ruciński, Karolina Pierzynowska, Danuta Wron. Age-dependent effects of dimethyl fumarate on cognitive and neuropathological features in the streptozotocin-induced rat model of Alzheimer's disease. Brain research. vol 1686. 2019-04-19. PMID:29453958. |
notably, within aged stz-injected rats, dmf treatment was associated with improved performance in mwm, reduced neurodegeneration in all hippocampal areas, reduced dg microglia activation, and reduced ca1 nitrotyrosine labeling compared to age-matched rats without dmf treatment. |
2019-04-19 |
2023-08-13 |
rat |
| Siok Lam Lim, Diana Nguyen Tran, Joannee Zumkehr, Christine Chen, Sagar Ghiaar, Zanett Kieu, Emmanuel Villanueva, Victoria Gallup, Carlos J Rodriguez-Ortiz, Masashi Kitazaw. Inhibition of hematopoietic cell kinase dysregulates microglial function and accelerates early stage Alzheimer's disease-like neuropathology. Glia. vol 66. issue 12. 2019-04-15. PMID:30277607. |
these multifactorial changes in microglial activities led to attenuated psd95 levels in hippocampal dg and ca3 regions, but did not alter the postsynaptic dendritic spine morphology at the ca1 region nor cognitive function of the mice. |
2019-04-15 |
2023-08-13 |
mouse |
| Baohui Zhai, Xueliang Shang, Jingxuan Fu, Fangjuan Li, Tao Zhan. Rapamycin relieves anxious emotion and synaptic plasticity deficits induced by hindlimb unloading in mice. Neuroscience letters. vol 677. 2019-04-09. PMID:29684531. |
afterwards, long-term potentiation (ltp) recorded in the hippocampal dentate gyrus (dg) region was effectively reduced by rapamycin, which was significantly inhibited by hu procedure. |
2019-04-09 |
2023-08-13 |
mouse |
| Shuang-Hong Tang, Yan-Jun Du, Jia-Huan Xiao, Yun Wang, Feng Shen, Guo-Jie Su. [Acupuncture and Moxibustion Improves Learning-memory Ability of Alzheimer's Disease Rats Possibly by Up-regulating Serum Aβ Internalization Enzyme Contents]. Zhen ci yan jiu = Acupuncture research. vol 43. issue 11. 2019-04-08. PMID:30585465. |
to observe the effect of acupuncture and moxibustion (am) on learning-memory ability and expression of amyloid beta (aβ) in the hippocampal dentate gyrus (dg) of alzheimer's disease (ad) rats, so as to explore its mechanism underlying improvement of ad. |
2019-04-08 |
2023-08-13 |
rat |
| Sita Sharan Patel, R S Ray, Arun Sharma, Vineet Mehta, Anju Katyal, Malairaman Udayaban. Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29704081. |
in addition, chronic diabetes significantly increased the expression of tnf-α in ca1 (p < 0.001), ca2 (p < 0.01), ca3 (p < 0.001) and dg (p < 0.001) regions of hippocampus as compared to control mice. |
2019-04-01 |
2023-08-13 |
mouse |
| Sita Sharan Patel, R S Ray, Arun Sharma, Vineet Mehta, Anju Katyal, Malairaman Udayaban. Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29704081. |
chronic diabetes mediated neuronal damage in the ca2, ca3 and dg regions of hippocampus. |
2019-04-01 |
2023-08-13 |
mouse |
| b' Andrijana Stanisavljevi\\xc4\\x87, Ivana Peri\\xc4\\x87, Peter Gass, Dragos Inta, Undine E Lang, Stefan Borgwardt, Dragana Filipovi\\xc4\\x8. Brain Sub/Region-Specific Effects of Olanzapine on c-Fos Expression of Chronically Socially Isolated Rats. Neuroscience. vol 396. 2019-04-01. PMID:30458222.' |
olz treatment reversed depression- and anxiety-like behaviors induced by csis and suppressed a csis-induced increase in the number of c-fos-positive cells in subregions of the dorsal hippocampus, ventral (v) dg, retrosplenial cortex, and medial prefrontal cortex. |
2019-04-01 |
2023-08-13 |
rat |
| Talita Matias Barbosa Cavalcante, José de Maria Albuquerque De Melo, Lia Bastos Lopes, Matheus Costa Bessa, Jéssica Gurgel Santos, Luna Costa Vasconcelos, Antônio Eufrásio Vieira Neto, Lucas Teixeira Nunes Borges, Marta Maria França Fonteles, Adriano José Maia Chaves Filho, Danielle Macêdo, Adriana Rolim Campos, Carlos Clayton Torres Aguiar, Silvânia Maria Mendes Vasconcelo. Ivabradine possesses anticonvulsant and neuroprotective action in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 109. 2019-04-01. PMID:30551511. |
immunohistochemistry analysis for cleaved caspase-3, a pro-apoptotic and degenerative marker, in hippocampal subregions namely cornu ammonis (ca)1, ca3 and dentate gyrus (dg), were also performed. |
2019-04-01 |
2023-08-13 |
mouse |
| Simone F Carron, Edwin B Yan, Benjamin J Allitt, Ramesh Raja. Immediate and Medium-term Changes in Cortical and Hippocampal Inhibitory Neuronal Populations after Diffuse TBI. Neuroscience. vol 388. 2019-03-29. PMID:30036662. |
however, dg of hippocampus now showed reduction of dendrite-targeting inhibitory neurons. |
2019-03-29 |
2023-08-13 |
Not clear |
| Yuta Senza. Function of local circuits in the hippocampal dentate gyrus-CA3 system. Neuroscience research. vol 140. 2019-03-28. PMID:30408501. |
anatomical observations, theoretical work and lesioning experiments have supported the idea that the ca3 in the hippocampus is important for encoding, storage and retrieval of memory while the dentate gyrus (dg) is important for the pattern separation of the incoming inputs from the entorhinal cortex. |
2019-03-28 |
2023-08-13 |
Not clear |
| Ali Sayyahi, Mehrdad Jahanshahi, Hossein Amini, Hamid Sepehr. Vitamin E can compensate the density of M1 receptors in the hippocampus of scopolamine-treated rats. Folia neuropathologica. vol 56. issue 3. 2019-03-28. PMID:30509043. |
vitamin e treatment significantly increased neuron numbers in the ca1 and ca3 areas of the hippocampus and dg area. |
2019-03-28 |
2023-08-13 |
rat |
| Sahreh Shabani, Mohammad Ali Mirsheka. Diosmin is neuroprotective in a rat model of scopolamine-induced cognitive impairment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-03-22. PMID:30372840. |
in this study, we have assessed the effects of administration of the diosmin (dm, 50 and 100 mg/kg), before injection of 0.4 mg/kg of scopolamine on memory and motor function, the hippocampal dentate gyrus (dg) electrophysiological activity as well as brain inflammation. |
2019-03-22 |
2023-08-13 |
rat |