| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dong-Hee Choi, In-Ae Choi, Cheol Soon Lee, Ji Hee Yun, Jongmin Le. The Role of NOX4 in Parkinson's Disease with Dementia. International journal of molecular sciences. vol 20. issue 3. 2019-05-29. PMID:30736297. |
our results suggest that increased expression of nox4 in the hippocampal dg in the 6-ohda-treated mouse induces aβ expression and oligomer a11 production, thereby reducing cognitive function. |
2019-05-29 |
2023-08-13 |
mouse |
| Nannan Guo, Marta E Soden, Charlotte Herber, Michael TaeWoo Kim, Antoine Besnard, Paoyan Lin, Xiang Ma, Constance L Cepko, Larry S Zweifel, Amar Saha. Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. Nature medicine. vol 24. issue 4. 2019-05-20. PMID:29529016. |
in the hippocampal dentate gyrus (dg), memories are thought to be encoded by so-called 'engram-bearing' dentate granule cells (edgcs). |
2019-05-20 |
2023-08-13 |
mouse |
| S Ray, M J Corenblum, A Anandhan, A Reed, F O Ortiz, D D Zhang, C A Barnes, L Madhava. A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells. Cell transplantation. vol 27. issue 4. 2019-05-17. PMID:29871525. |
since nrf2 is a major transcription factor at the heart of cellular redox regulation and homeostasis, the current study investigates the role that it may play in the aging of nspcs that reside within the other major mammalian germinal niche located in the subgranular zone (sgz) of the dentate gyrus (dg) of the hippocampus. |
2019-05-17 |
2023-08-13 |
mouse |
| S Ray, M J Corenblum, A Anandhan, A Reed, F O Ortiz, D D Zhang, C A Barnes, L Madhava. A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells. Cell transplantation. vol 27. issue 4. 2019-05-17. PMID:29871525. |
furthermore, the enrichment of the hippocampal environment via the transplantation of nrf2-overexpressing nspcs was able to mitigate the age-related decline in dg stem cell regeneration during the critical middle-age period, and significantly improved pattern separation abilities. |
2019-05-17 |
2023-08-13 |
mouse |
| Takuya Sasaki, Verónica C Piatti, Ernie Hwaun, Siavash Ahmadi, John E Lisman, Stefan Leutgeb, Jill K Leutge. Dentate network activity is necessary for spatial working memory by supporting CA3 sharp-wave ripple generation and prospective firing of CA3 neurons. Nature neuroscience. vol 21. issue 2. 2019-05-16. PMID:29335604. |
complex spatial working memory tasks have been shown to require both hippocampal sharp-wave ripple (swr) activity and dentate gyrus (dg) neuronal activity. |
2019-05-16 |
2023-08-13 |
rat |
| Lin Jiang, Jing Ma, Yi Zhang, Chun-Ni Zhou, Lei Zhang, Feng-Lei Chao, Lin-Mu Chen, Rong Jiang, Hong Wu, Yong Tan. Effect of running exercise on the number of the neurons in the hippocampus of young transgenic APP/PS1 mice. Brain research. vol 1692. 2019-05-08. PMID:29715445. |
the stereological methods were used to quantitatively evaluate the volume of the hippocampus, ca1/2, ca3 and the dentate gyrus (dg) and count the number of the neurons in ca1/2, ca3 and dg. |
2019-05-08 |
2023-08-13 |
mouse |
| Lin Jiang, Jing Ma, Yi Zhang, Chun-Ni Zhou, Lei Zhang, Feng-Lei Chao, Lin-Mu Chen, Rong Jiang, Hong Wu, Yong Tan. Effect of running exercise on the number of the neurons in the hippocampus of young transgenic APP/PS1 mice. Brain research. vol 1692. 2019-05-08. PMID:29715445. |
more importantly, 4-month running effectively increased the volumes of the hippocampus, ca1/2, ca3 and dg and increased the number of neurons in ca1/2, ca3 and dg in young app/ps1 mice. |
2019-05-08 |
2023-08-13 |
mouse |
| Lin Jiang, Jing Ma, Yi Zhang, Chun-Ni Zhou, Lei Zhang, Feng-Lei Chao, Lin-Mu Chen, Rong Jiang, Hong Wu, Yong Tan. Effect of running exercise on the number of the neurons in the hippocampus of young transgenic APP/PS1 mice. Brain research. vol 1692. 2019-05-08. PMID:29715445. |
the present results suggested that 4-month running has significant beneficial effects on the spatial learning and memory capacities of young app/ps1 mice and could delay the progress of atrophy of hippocampus and the neuron death in ca1/2, ca3 and dg in young app/ps1 mice. |
2019-05-08 |
2023-08-13 |
mouse |
| F Scharkowski, Michael Frotscher, David Lutz, Martin Korte, Kristin Michaelsen-Preuss. Altered Connectivity and Synapse Maturation of the Hippocampal Mossy Fiber Pathway in a Mouse Model of the Fragile X Syndrome. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 3. 2019-05-07. PMID:28077511. |
surprisingly, one of the most complex hippocampal synapses connecting the dentate gyrus (dg) to ca3 pyramidal neurons has not been analyzed in fxs yet. |
2019-05-07 |
2023-08-13 |
mouse |
| N C Woodward, A Haghani, R G Johnson, T M Hsu, A Saffari, C Sioutas, S E Kanoski, C E Finch, T E Morga. Prenatal and early life exposure to air pollution induced hippocampal vascular leakage and impaired neurogenesis in association with behavioral deficits. Translational psychiatry. vol 8. issue 1. 2019-05-06. PMID:30498214. |
at age 5 months, exposed male rats had 70% fewer newly generated neurons in the dentate gyrus (dg) of the hippocampus. |
2019-05-06 |
2023-08-13 |
human |
| Tania Campos-Ordonez, David Zarate-Lopez, Nereida Ibarra-Castaneda, Jonathan Buritica, Oscar Gonzalez-Pere. Cyclohexane Inhalation Produces Long-Lasting Alterations in the Hippocampal Integrity and Reward-Seeking Behavior in the Adult Mouse. Cellular and molecular neurobiology. vol 39. issue 3. 2019-05-06. PMID:30771197. |
this study aimed to establish the behavioral changes and the pathological alterations that occur in the cornu ammonis 3 (ca3) and dentate gyrus (dg) after a long-lasting exposure to chx. |
2019-05-06 |
2023-08-13 |
mouse |
| Tania Campos-Ordonez, David Zarate-Lopez, Nereida Ibarra-Castaneda, Jonathan Buritica, Oscar Gonzalez-Pere. Cyclohexane Inhalation Produces Long-Lasting Alterations in the Hippocampal Integrity and Reward-Seeking Behavior in the Adult Mouse. Cellular and molecular neurobiology. vol 39. issue 3. 2019-05-06. PMID:30771197. |
we exposed cd1 mice to a recreational-like dose of chx (~ 30,000 ppm) for 30 days and explored its consequences in motor skills, reward-seeking behavior, and the ca3 and dg hippocampal subfields. |
2019-05-06 |
2023-08-13 |
mouse |
| Dwi Liliek Kusindarta, Hevi Wihadmadyatami, Arvendi R Jadi, Srikanth Karnati, Guenter Lochnit, Puspa Hening, Aris Haryanto, Made B Auriva, Medania Purwaningru. Ethanolic extract Ocimum sanctum. Enhances cognitive ability from young adulthood to middle aged mediated by increasing choline acetyl transferase activity in rat model. Research in veterinary science. vol 118. 2019-05-02. PMID:29729605. |
further, nissl staining was performed to analyze hippocampus formation in dentate gyrus (dg), cornu ammonis 1 (ca1), cornu ammonis 3 (ca3). |
2019-05-02 |
2023-08-13 |
rat |
| Dong Sun, Xiang-Dong Sun, Lu Zhao, Dae-Hoon Lee, Jin-Xia Hu, Fu-Lei Tang, Jin-Xiu Pan, Lin Mei, Xiao-Juan Zhu, Wen-Cheng Xion. Neogenin, a regulator of adult hippocampal neurogenesis, prevents depressive-like behavior. Cell death & disease. vol 9. issue 1. 2019-04-30. PMID:29311593. |
adult neurogenesis in hippocampal dentate gyrus (dg) is a complex, but precisely controlled process. |
2019-04-30 |
2023-08-13 |
mouse |
| Shitong Xiang, Yu Zhou, Jingxuan Fu, Tao Zhan. rTMS pre-treatment effectively protects against cognitive and synaptic plasticity impairments induced by simulated microgravity in mice. Behavioural brain research. vol 359. 2019-04-23. PMID:30292903. |
in the hippocampus dg and ca1 regions, dendritic spine density was measured using golgi-cox staining. |
2019-04-23 |
2023-08-13 |
mouse |
| Irena Majkutewicz, Ewelina Kurowska, Magdalena Podlacha, Dorota Myślińska, Beata Grembecka, Jan Ruciński, Karolina Pierzynowska, Danuta Wron. Age-dependent effects of dimethyl fumarate on cognitive and neuropathological features in the streptozotocin-induced rat model of Alzheimer's disease. Brain research. vol 1686. 2019-04-19. PMID:29453958. |
notably, within aged stz-injected rats, dmf treatment was associated with improved performance in mwm, reduced neurodegeneration in all hippocampal areas, reduced dg microglia activation, and reduced ca1 nitrotyrosine labeling compared to age-matched rats without dmf treatment. |
2019-04-19 |
2023-08-13 |
rat |
| Siok Lam Lim, Diana Nguyen Tran, Joannee Zumkehr, Christine Chen, Sagar Ghiaar, Zanett Kieu, Emmanuel Villanueva, Victoria Gallup, Carlos J Rodriguez-Ortiz, Masashi Kitazaw. Inhibition of hematopoietic cell kinase dysregulates microglial function and accelerates early stage Alzheimer's disease-like neuropathology. Glia. vol 66. issue 12. 2019-04-15. PMID:30277607. |
these multifactorial changes in microglial activities led to attenuated psd95 levels in hippocampal dg and ca3 regions, but did not alter the postsynaptic dendritic spine morphology at the ca1 region nor cognitive function of the mice. |
2019-04-15 |
2023-08-13 |
mouse |
| Baohui Zhai, Xueliang Shang, Jingxuan Fu, Fangjuan Li, Tao Zhan. Rapamycin relieves anxious emotion and synaptic plasticity deficits induced by hindlimb unloading in mice. Neuroscience letters. vol 677. 2019-04-09. PMID:29684531. |
afterwards, long-term potentiation (ltp) recorded in the hippocampal dentate gyrus (dg) region was effectively reduced by rapamycin, which was significantly inhibited by hu procedure. |
2019-04-09 |
2023-08-13 |
mouse |
| Shuang-Hong Tang, Yan-Jun Du, Jia-Huan Xiao, Yun Wang, Feng Shen, Guo-Jie Su. [Acupuncture and Moxibustion Improves Learning-memory Ability of Alzheimer's Disease Rats Possibly by Up-regulating Serum Aβ Internalization Enzyme Contents]. Zhen ci yan jiu = Acupuncture research. vol 43. issue 11. 2019-04-08. PMID:30585465. |
to observe the effect of acupuncture and moxibustion (am) on learning-memory ability and expression of amyloid beta (aβ) in the hippocampal dentate gyrus (dg) of alzheimer's disease (ad) rats, so as to explore its mechanism underlying improvement of ad. |
2019-04-08 |
2023-08-13 |
rat |
| Sita Sharan Patel, R S Ray, Arun Sharma, Vineet Mehta, Anju Katyal, Malairaman Udayaban. Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29704081. |
in addition, chronic diabetes significantly increased the expression of tnf-α in ca1 (p < 0.001), ca2 (p < 0.01), ca3 (p < 0.001) and dg (p < 0.001) regions of hippocampus as compared to control mice. |
2019-04-01 |
2023-08-13 |
mouse |