| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chrysoula Dioli, Patrícia Patrício, Nuno Sousa, Nikolaos Kokras, Christina Dalla, Sara Guerreiro, Miguel A Santos-Silva, Ana Cristina Rego, Luísa Pinto, Elisabete Ferreiro, Ioannis Sotiropoulo. Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields. Translational psychiatry. vol 9. issue 1. 2020-01-09. PMID:31028242. |
these findings suggest that the neuroplastic effects of chronic stress on dendritic maturation and complexity of dcx+ immature neurons vary based on the different maturation stage of dcx-positive cells and the different dg sublayer, highlighting the complex and dynamic stress-driven neuroplasticity of immature neurons in the adult hippocampus. |
2020-01-09 |
2023-08-13 |
Not clear |
| Véronique Deroche-Gamonet, Jean-Michel Revest, Jean-François Fiancette, Eric Balado, Muriel Koehl, Noëlle Grosjean, Djoher Nora Abrous, Pier-Vincenzo Piazz. Depleting adult dentate gyrus neurogenesis increases cocaine-seeking behavior. Molecular psychiatry. vol 24. issue 2. 2020-01-06. PMID:29507372. |
the hippocampus is the main locus for adult dentate gyrus (dg) neurogenesis. |
2020-01-06 |
2023-08-13 |
mouse |
| Yoo Jin Shin, Yeon Tae Chun, Sun Woo Lim, Kang Luo, Yi Quan, Sheng Cui, Eun Jeong Ko, Byung Ha Chung, Jiyeong Lee, Seongno Hong, Mun Yong Lee, Hee Gyoo Kang, Chul Woo Yan. Influence of Tacrolimus on Depressive-Like Behavior in Diabetic Rats Through Brain-Derived Neurotrophic Factor Regulation in the Hippocampus. Neurotoxicity research. vol 36. issue 2. 2020-01-02. PMID:31201731. |
bdnf expression in the hippocampus was examined in the dentate gyrus (dg) and ca3 region using immunohistochemistry. |
2020-01-02 |
2023-08-13 |
rat |
| Rebecca K West, Jessica I Wooden, Emily A Barton, J Leigh Leasur. Recurrent binge ethanol is associated with significant loss of dentate gyrus granule neurons in female rats despite concomitant increase in neurogenesis. Neuropharmacology. vol 148. 2019-12-27. PMID:30659841. |
using stereology, we quantified the number and/or size of neurons in the medial prefrontal cortex (mpfc) and hippocampal dentate gyrus (dg), as well as the number and activation state of microglia. |
2019-12-27 |
2023-08-13 |
rat |
| James E Delorme, Varna Kodoth, Sara J Ato. Sleep loss disrupts Arc expression in dentate gyrus neurons. Neurobiology of learning and memory. vol 160. 2019-12-24. PMID:29635031. |
using in situ hybridization (together with behavioral observation to quantify sleep amounts), we find that in the dorsal hippocampus, sd minimally affects arc mrna expression, and decreases the number of dentate gyrus (dg) granule cells expressing arc. |
2019-12-24 |
2023-08-13 |
mouse |
| Claire E Manning, Andrew L Eagle, Christine C Kwiatkowski, Ridouane Achargui, Hillary Woodworth, Emily Potter, Yoshinori Ohnishi, Gina M Leinninger, A J Robiso. Hippocampal Subgranular Zone FosB Expression Is Critical for Neurogenesis and Learning. Neuroscience. vol 406. 2019-12-24. PMID:30902680. |
here, we crossed neurotensin receptor-2 (ntsr2) cre mice, which express cre within the subgranular zone (sgz) of dhpc dg, with floxed fosb mice to show that knockout of Δfosb in hippocampal sgz neurons reduces antidepressant-induced neurogenesis and impedes hippocampus-dependent learning in the novel object recognition task. |
2019-12-24 |
2023-08-13 |
mouse |
| Stanislau Hrybouski, Melanie MacGillivray, Yushan Huang, Christopher R Madan, Rawle Carter, Peter Seres, Nikolai V Malykhi. Involvement of hippocampal subfields and anterior-posterior subregions in encoding and retrieval of item, spatial, and associative memories: Longitudinal versus transverse axis. NeuroImage. vol 191. 2019-12-20. PMID:30742981. |
the hippocampus can be segmented into three major anteroposterior sections, called head, body and tail, and into the cornu ammonis (ca), dentate gyrus (dg), and subiculum (sub) subfields based on its transverse axis. |
2019-12-20 |
2023-08-13 |
human |
| Nasrin Hamidi, Abdollah Nozad, Hamid Sheikhkanloui Milan, Mohammad Aman. Okadaic acid attenuates short-term and long-term synaptic plasticity of hippocampal dentate gyrus neurons in rats. Neurobiology of learning and memory. vol 158. 2019-12-17. PMID:30630043. |
the aim of this study was to examine the effect of oka on electrophysiological characteristics of hippocampal dentate gyrus (dg) neurons in vivo. |
2019-12-17 |
2023-08-13 |
rat |
| Nasrin Hamidi, Abdollah Nozad, Hamid Sheikhkanloui Milan, Mohammad Aman. Okadaic acid attenuates short-term and long-term synaptic plasticity of hippocampal dentate gyrus neurons in rats. Neurobiology of learning and memory. vol 158. 2019-12-17. PMID:30630043. |
results of this study revealed that oka-induced inhibition of pp1 and pp2a activity drastically attenuates the field excitatory postsynaptic potential (fepsp) slope and population spike (ps) amplitude following paired pulse and high frequency stimulation (hfs) of hippocampal dg neurons indicating pre- and post-synaptic involvement in electrical activity of these neurons. |
2019-12-17 |
2023-08-13 |
rat |
| Rubén D Castro-Torres, Jon Landa, Marina Rabaza, Oriol Busquets, Jordi Olloquequi, Miren Ettcheto, Carlos Beas-Zarate, Jaume Folch, Antoni Camins, Carme Auladell, Ester Verdague. JNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy. Molecular neurobiology. vol 56. issue 8. 2019-12-17. PMID:30685843. |
neurogenesis in the adult dentate gyrus (dg) of the hippocampus allows the continuous generation of new neurons. |
2019-12-17 |
2023-08-13 |
mouse |
| Minhui Gao, Peili Hu, Zixuan Cai, Yue Wu, Dan Wang, Wenfeng Hu, Xing Xu, Yaru Zhang, Xu Lu, Dongjian Chen, Zhuo Chen, Kai Ma, Jie Wen, Hui Wang, Chao Huan. Identification of a microglial activation-dependent antidepressant effect of amphotericin B liposome. Neuropharmacology. vol 151. 2019-12-10. PMID:30954529. |
immunofluorescence analysis showed that amphotericin b liposome reversed the cus-induced decline in dentate gyrus (dg) microglia, and inhibition or ablation of microglia in the hippocampus by minocycline (40 mg/kg) or plx3397 pre-treatment (290 mg/kg) abrogated the antidepressant effect of the amphotericin b liposome in cus-treated mice. |
2019-12-10 |
2023-08-13 |
mouse |
| Lily Wan, Tian Tu, Qi-Lei Zhang, Juan Jiang, Xiao-Xin Ya. Pregnancy Promotes Maternal Hippocampal Neurogenesis in Guinea Pigs. Neural plasticity. vol 2019. 2019-12-10. PMID:31097956. |
adult neurogenesis in the hippocampal dentate gyrus (dg) modulates cognition and behavior in mammals, while motherhood is associated with cognitive and behavioral changes essential for the care of the young. |
2019-12-10 |
2023-08-13 |
mouse |
| Elif Tunc-Ozcan, Chian-Yu Peng, Yiwen Zhu, Sara R Dunlop, Anis Contractor, John A Kessle. Activating newborn neurons suppresses depression and anxiety-like behaviors. Nature communications. vol 10. issue 1. 2019-12-09. PMID:31434877. |
the neurogenic hypothesis proposes that mdd is linked to impairments of adult neurogenesis in the hippocampal dentate gyrus (dg), while the effects of antidepressants are mediated by increased neurogenesis. |
2019-12-09 |
2023-08-13 |
mouse |
| Faezeh Nemati Karimooy, Alireza Ebrahimzadeh Bideskan, Abbas Mohammadi Pour, Seyed Mahmoud Hosein. Neurotoxic Effects of Stanozolol on Male Rats' Hippocampi: Does Stanozolol cause apoptosis? Biomolecular concepts. vol 10. issue 1. 2019-11-20. PMID:31026221. |
histopathological examination revealed that the mean number of pre-apoptotic and apoptotic neurons in the ca1, ca2, ca3 and dg areas of the hippocampus were significantly increased in the stanozolol treated group. |
2019-11-20 |
2023-08-13 |
rat |
| Enrique Becerril-Villanueva, María Dolores Ponce-Regalado, Gilberto Pérez-Sánchez, Alberto Salazar-Juárez, Rodrigo Arreola, María Elizbeth Álvarez-Sánchez, Mario Juárez-Ortega, Ramcés Falfán-Valencia, Rogelio Hernández-Pando, Jorge Morales-Montor, Lenin Pavón, Oscar Rojas-Espinos. Chronic infection with Mycobacterium lepraemurium induces alterations in the hippocampus associated with memory loss. Scientific reports. vol 8. issue 1. 2019-11-18. PMID:29899533. |
to evaluate working memory, we used the t-maze while a morphometric analysis was conducted in the hippocampus regions ca1, ca2, ca3, and dentate gyrus (dg) to measure morphological changes. |
2019-11-18 |
2023-08-13 |
mouse |
| Yuki Hashimotodani, Fuyuki Karube, Yuchio Yanagawa, Fumino Fujiyama, Masanobu Kan. Supramammillary Nucleus Afferents to the Dentate Gyrus Co-release Glutamate and GABA and Potentiate Granule Cell Output. Cell reports. vol 25. issue 10. 2019-11-13. PMID:30517859. |
the supramammillary nucleus (sum) of the hypothalamus projects to the dentate gyrus (dg) and the ca2 region of the hippocampus. |
2019-11-13 |
2023-08-13 |
Not clear |
| Sara Bonzano, Isabella Crisci, Anna Podlesny-Drabiniok, Chiara Rolando, Wojciech Krezel, Michèle Studer, Silvia De Marchi. Neuron-Astroglia Cell Fate Decision in the Adult Mouse Hippocampal Neurogenic Niche Is Cell-Intrinsically Controlled by COUP-TFI In Vivo. Cell reports. vol 24. issue 2. 2019-11-07. PMID:29996095. |
in the dentate gyrus (dg) of the mouse hippocampus, neurogenesis and astrogliogenesis persist throughout life. |
2019-11-07 |
2023-08-13 |
mouse |
| Dongning Su, Hui Liu, Tianrong Liu, Xin Zhang, Wei Yang, Yizhi Song, Jinping Liu, Yan Wu, Lirong Chan. Dynamic SAP102 expression in the hippocampal subregions of rats and APP/PS1 mice of various ages. Journal of anatomy. vol 232. issue 6. 2019-11-06. PMID:29574717. |
in wistar rats, sap102 was not only highly expressed in the hippocampal subregions of neonatal rats but also maintained relatively high expression levels in adult hippocampi and displayed no obvious decreases in the ca1 and dg subregions of aged rats. |
2019-11-06 |
2023-08-13 |
mouse |
| Joanna Ruth Appel, Shiyang Ye, Fulei Tang, Dong Sun, Hongsheng Zhang, Lin Mei, Wen-Cheng Xion. Increased Microglial Activity, Impaired Adult Hippocampal Neurogenesis, and Depressive-like Behavior in Microglial VPS35-Depleted Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 26. 2019-10-28. PMID:29853629. |
conditional knocking out of vps35 in microglia of male mice results in regionally increased microglial density and activity in the subgranular zone of the hippocampal dentate gyrus (dg), accompanied by elevated neural progenitor proliferation, but decreased neuronal differentiation. |
2019-10-28 |
2023-08-13 |
mouse |
| Khushboo Srivastava, Ratnakar Tripathi, Rajnikant Mishr. Age-dependent alterations in expression and co-localization of Pax6 and Ras-GAP in brain of aging mice. Journal of chemical neuroanatomy. vol 92. 2019-10-22. PMID:29787792. |
the co-localization of pax6 and ras-gap were observed in dentate gyrus (dg) and sub-granular zone (sgz) of hippocampus, in glomerular (glla) and mitral cells (mice) of olfactory lobe, granular cells (grce), purkinje cell (puce) and molecular cell layer (mola) of cerebellum, internal plexiform layer (inpl), molecular layer (mola) of cerebral cortex and in intercalated cells of amygdala (itc), caudate nucleus regions in brain of aging mice. |
2019-10-22 |
2023-08-13 |
mouse |