| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dayana Hayek, Friederike Thams, Agnes Flöel, Daria Antonenk. Dentate Gyrus Volume Mediates the Effect of Fornix Microstructure on Memory Formation in Older Adults. Frontiers in aging neuroscience. vol 12. 2020-09-28. PMID:32265687. |
reduced microstructure of the fornix, the major efferent pathway of the hippocampus, and volume of the dentate gyrus (dg), may cause age-associated memory decline. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jake T Jordan, M Regis Shanley, Carolyn L Pytt. Behavioral state-dependent lateralization of dorsal dentate gyrus c-Fos expression in mice. Neuronal signaling. vol 3. issue 1. 2020-09-28. PMID:32269834. |
to understand functional lateralization of hippocampal processing, we compared interhemispheric expression of c-fos in the dentate gyrus (dg), a structure involved in encoding new experiences, in mice that ran on a wheel, encoded a novel object, or remained in home cages. |
2020-09-28 |
2023-08-13 |
mouse |
| Yuxiao Zhao, Pan Shang, Meijian Wang, Min Xie, Jian Li. Neuroprotective Effects of Fluoxetine Against Chronic Stress-Induced Neural Inflammation and Apoptosis: Involvement of the p38 Activity. Frontiers in physiology. vol 11. 2020-09-28. PMID:32477152. |
for 2 weeks ameliorated depression-like behaviors in a chronic unpredictable mild stress (cums)-induced rat model of depression and was accompanied with an alleviation of glia activation and inhibition of interleukin-1β (il-1β), interferon gamma (ifn-γ), and tumor necrosis factor-α (tnf-α) expression in the hippocampal dentate gyrus (dg) region. |
2020-09-28 |
2023-08-13 |
rat |
| Yuxiao Zhao, Pan Shang, Meijian Wang, Min Xie, Jian Li. Neuroprotective Effects of Fluoxetine Against Chronic Stress-Induced Neural Inflammation and Apoptosis: Involvement of the p38 Activity. Frontiers in physiology. vol 11. 2020-09-28. PMID:32477152. |
these effects appear to involve a downregulation of p38 mitogen-activated protein kinase (mapk) signaling within the dg hippocampus as the specific inhibitor of p38 mapk, sb203580, significantly suppressed apoptosis, as well as ameliorated depressive behaviors resulting from cums exposure. |
2020-09-28 |
2023-08-13 |
rat |
| Gibrán Gómez-Correa, Angelica Zeped. Chronic Bumetanide Infusion Alters Young Neuron Morphology in the Dentate Gyrus Without Affecting Contextual Fear Memory. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32508587. |
they integrate in the dentate gyrus (dg) of the hippocampus contributing to such cognitive processes following timely developmental events. |
2020-09-28 |
2023-08-13 |
Not clear |
| Azam Ghanbari-Maman, Forouzan Ghasemian-Roudsari, Shayan Aliakbari, Hamid Gholami Pourbadie, Fariba Khodagholi, Fatemeh Shaerzadeh, Mahtab Daftar. Calcium Channel Blockade Ameliorates Endoplasmic Reticulum Stress in the Hippocampus Induced by Amyloidopathy in the Entorhinal Cortex. Iranian journal of pharmaceutical research : IJPR. vol 18. issue 3. 2020-09-28. PMID:32641955. |
grp78/bip and chop levels were measured in the hippocampal dentate gyrus (dg) by western blot technique. |
2020-09-28 |
2023-08-13 |
rat |
| Soraya Martín-Suárez, Oihane Abiega, Ana Ricobaraza, Rubén Hernandez-Alcoceba, Juan Manuel Encina. Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome. Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32793597. |
hippocampal neurogenesis, the process by which neural stem cells (nscs) continuously generate new neurons in the dentate gyrus (dg) of most mammals including humans, is chiefly regulated by neuronal activity. |
2020-09-28 |
2023-08-13 |
mouse |
| Patrícia Patrício, António Mateus-Pinheiro, Nuno Dinis Alves, Mónica Morais, Ana João Rodrigues, João Miguel Bessa, Nuno Sousa, Luísa Pint. miR-409 and miR-411 Modulation in the Adult Brain of a Rat Model of Depression and After Fluoxetine Treatment. Frontiers in behavioral neuroscience. vol 14. 2020-09-28. PMID:32848656. |
previous microarray analysis from our group has disclosed molecular players in the hippocampal dentate gyrus (dg), in the context of depression and antidepressant treatment. |
2020-09-28 |
2023-08-13 |
rat |
| Mary Youssef, Piray Atsak, Jovani Cardenas, Stylianos Kosmidis, E David Leonardo, Alex Dranovsk. Early life stress delays hippocampal development and diminishes the adult stem cell pool in mice. Scientific reports. vol 9. issue 1. 2020-09-24. PMID:30858462. |
the long-term behavioral consequences of early life stress may therefore be due in part to interference with hippocampal development, in particular with assembly of the dentate gyrus (dg) region of the hippocampus. |
2020-09-24 |
2023-08-13 |
mouse |
| Mary Youssef, Piray Atsak, Jovani Cardenas, Stylianos Kosmidis, E David Leonardo, Alex Dranovsk. Early life stress delays hippocampal development and diminishes the adult stem cell pool in mice. Scientific reports. vol 9. issue 1. 2020-09-24. PMID:30858462. |
these results suggest a developmental mechanism by which early life stress can induce long-term changes in hippocampal function by interfering with dg assembly and ultimately diminishing the adult stem cell pool. |
2020-09-24 |
2023-08-13 |
mouse |
| Golo Kronenberg, Karen Gertz, Ria Uhlemann, Melanie T C Kuffner, Imke Kirste, Junfeng An, Nafisa M Jadavji, Bjoern H Schott, Thomas Scheffel, Matthias Endres, Rainer Hellweg, Christoph Harm. Reduced Hippocampal Neurogenesis in Mice Deficient in Apoptosis Repressor with Caspase Recruitment Domain (ARC). Neuroscience. vol 416. 2020-09-24. PMID:31356897. |
in the adult hippocampal dentate gyrus (dg), the majority of newly generated cells are eliminated by apoptotic mechanisms. |
2020-09-24 |
2023-08-13 |
mouse |
| Mahsa Pourhamzeh, Roghaye Mozafari, Shole Jamali, Fereshteh Motamedi, Reza Ahadi, Abbas Haghparas. Involvement of orexin receptors within the hippocampal dentate gyrus in morphine-induced reinstatement in food-deprived rats. Behavioural brain research. vol 375. 2020-09-22. PMID:31422071. |
the orexinergic terminals innervate neurons of the hippocampal dentate gyrus (dg) which is a key structure in the maintenance and reinstatement of drug addiction. |
2020-09-22 |
2023-08-13 |
rat |
| Jianxing Lian, Kai Li, Jing Gao, Xiaoyue Tan, Zhuo Yan. Legumain acts on neuroinflammatory to affect CUS-induced cognitive impairment. Behavioural brain research. vol 376. 2020-09-22. PMID:31509774. |
additionally, cus exposure significantly decreased the expression of hippocampal synapse related proteins and the cell density in the dg region, accompanied by increasing the expression of hippocampal inflammatory cytokines and promoting the activation of microglia in the hippocampus. |
2020-09-22 |
2023-08-13 |
mouse |
| Shauna M Stark, C Brock Kirwan, Craig E L Star. Mnemonic Similarity Task: A Tool for Assessing Hippocampal Integrity. Trends in cognitive sciences. vol 23. issue 11. 2020-09-22. PMID:31597601. |
the hippocampus is critical for learning and memory, relying in part on pattern separation processes supported by the dentate gyrus (dg) to prevent interference from overlapping memory representations. |
2020-09-22 |
2023-08-13 |
Not clear |
| Shauna M Stark, C Brock Kirwan, Craig E L Star. Mnemonic Similarity Task: A Tool for Assessing Hippocampal Integrity. Trends in cognitive sciences. vol 23. issue 11. 2020-09-22. PMID:31597601. |
the mst is now a widely used behavioral task, repeatedly shown to be sensitive to age-related memory decline, hippocampal connectivity, and hippocampal function, with specificity to the dg. |
2020-09-22 |
2023-08-13 |
Not clear |
| Shoji Nishida, Ryota Araki, Akihiro Baba, Sota Asari, Shin Tachibana, Yuki Nakajima, Arimi Iwakumo, Takeshi Yab. Post-weaning folate deficiency induces a depression-like state via neuronal immaturity of the dentate gyrus in mice. Journal of pharmacological sciences. vol 143. issue 2. 2020-09-15. PMID:32173264. |
in the dentate gyrus (dg) of the hippocampus, decreased number of newborn mature neurons and increased number of immature neurons were observed in low folate diet-fed mice. |
2020-09-15 |
2023-08-13 |
mouse |
| Zahra Shabani, Javad Mahmoudi, Fereshteh Farajdokht, Saeed Sadigh-Etegha. An Overview of Nicotinic Cholinergic System Signaling in Neurogenesis. Archives of medical research. vol 51. issue 4. 2020-09-15. PMID:32279909. |
the subventricular zone (svz), lining the lateral ventricle, and the subgranular zone (sgz), which is in the dentate gyrus (dg) of the hippocampus, are the central regions of neurogenesis in the brain. |
2020-09-15 |
2023-08-13 |
Not clear |
| Janasha Goffigan-Holmes, Dafne Sanabria, Johana Diaz, Debra Flock, Raul Chavez-Valde. Calbindin-1 Expression in the Hippocampus following Neonatal Hypoxia-Ischemia and Therapeutic Hypothermia and Deficits in Spatial Memory. Developmental neuroscience. 2020-09-12. PMID:30861522. |
in both anterior and posterior coronal brain sections, hippocampal calb1 expression doubled between p11 and p40 due to an increase in the cornus ammonis (ca) field (kruskal-wallis [kw] p < 0.001) and not the dentate gyrus (dg). |
2020-09-12 |
2023-08-13 |
mouse |
| Pascal J D Goetghebeur, Keith A Wesnes, Steven D Targu. D-Cycloserine Improves Difficult Discriminations in a Pattern Separation Task in Alzheimer's Disease Patients with Dementia. Journal of Alzheimer's disease : JAD. vol 69. issue 2. 2020-09-10. PMID:30958353. |
recent fmri studies in human identified that pattern separation ability is associated with increased activity in the hippocampal dentate gyrus (dg), whereas no such dg changes are seen during pattern completion. |
2020-09-10 |
2023-08-13 |
human |
| Runrui Zhang, Marcelo Boareto, Anna Engler, Angeliki Louvi, Claudio Giachino, Dagmar Iber, Verdon Taylo. Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus. Cell reports. vol 28. issue 6. 2020-09-09. PMID:31390563. |
neural stem cells (nscs) in the adult mouse hippocampal dentate gyrus (dg) are mostly quiescent, and only a few are in cell cycle at any point in time. |
2020-09-09 |
2023-08-13 |
mouse |