| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Ying Zhang, Wang Wei, You-Zhi Zhang, Qiang Fu, Wei-Dong Mi, Li-Ming Zhang, Yun-Feng L. The 18 kDa Translocator Protein (TSPO) Overexpression in Hippocampal Dentate Gyrus Elicits Anxiolytic-Like Effects in a Mouse Model of Post-traumatic Stress Disorder. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:30532709. |
this study is testing the hypothesis that the overexpression of tspo in hippocampus dentate gyrus (dg) could alleviate the anxiogenic-like response in the mice model of ptsd induced by foot-shock. |
2020-09-30 |
2023-08-13 |
mouse |
| Xiao-Ying Zhang, Wang Wei, You-Zhi Zhang, Qiang Fu, Wei-Dong Mi, Li-Ming Zhang, Yun-Feng L. The 18 kDa Translocator Protein (TSPO) Overexpression in Hippocampal Dentate Gyrus Elicits Anxiolytic-Like Effects in a Mouse Model of Post-traumatic Stress Disorder. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:30532709. |
in this study, hippocampal dg overexpression of tspo significantly reversed the increase of the contextual freezing response, the decrease of the percentage of both entries into and time spent in the open arms in elevated plus maze test and the decrease of the account of crossings from the dark to light compartments in light-dark transition test induced by electric foot-shocks procedure. |
2020-09-30 |
2023-08-13 |
mouse |
| Anthony J DeCostanzo, Chi Chung Alan Fung, Tomoki Fuka. Hippocampal Neurogenesis Reduces the Dimensionality of Sparsely Coded Representations to Enhance Memory Encoding. Frontiers in computational neuroscience. vol 12. 2020-09-30. PMID:30666194. |
adult neurogenesis in the hippocampal dentate gyrus (dg) of mammals is known to contribute to memory encoding in many tasks. |
2020-09-30 |
2023-08-13 |
Not clear |
| Kyounghye Lee, Hyuk Wan K. Repeated restraint stress promotes hippocampal neuronal cell ciliogenesis and proliferation in mice. Laboratory animal research. vol 34. issue 4. 2020-09-30. PMID:30671106. |
interestingly, rst stress increased the number of ciliated cells in the adult hippocampal dentate gyrus (dg). |
2020-09-30 |
2023-08-13 |
mouse |
| Kyounghye Lee, Hyuk Wan K. Repeated restraint stress promotes hippocampal neuronal cell ciliogenesis and proliferation in mice. Laboratory animal research. vol 34. issue 4. 2020-09-30. PMID:30671106. |
moreover, the analysis of ciliated cells in the hippocampal dg with cell type markers indicated that cells that were ciliated in response to acute rst stress are neurons. |
2020-09-30 |
2023-08-13 |
mouse |
| Qinghua Zeng, Zhimin Long, Min Feng, Yueyang Zhao, Shifang Luo, Kejian Wang, Yingxiong Wang, Guang Yang, Guiqiong H. Valproic Acid Stimulates Hippocampal Neurogenesis Frontiers in aging neuroscience. vol 11. 2020-09-30. PMID:30971911. |
vpa treatment promoted cell proliferation and increased the density of immature neurons in the dentate gyrus (dg) of the hippocampus of 3xtgad mice. |
2020-09-30 |
2023-08-13 |
mouse |
| Rocío Beatriz Foltran, Karen Melany Stefani, Antonela Bonafina, Agustina Resasco, Silvina Laura Dia. Differential Hippocampal Expression of BDNF Isoforms and Their Receptors Under Diverse Configurations of the Serotonergic System in a Mice Model of Increased Neuronal Survival. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31555094. |
in particular, the brain-derived neurotrophic factor, bdnf, is highly expressed in the hippocampus (hc) of rodents and participates in the control of neuronal proliferation, and survival in the dentate gyrus (dg). |
2020-09-30 |
2023-08-13 |
mouse |
| Valentyna Dubovyk, Denise Manahan-Vaugha. Gradient of Expression of Dopamine D2 Receptors Along the Dorso-Ventral Axis of the Hippocampus. Frontiers in synaptic neuroscience. vol 11. 2020-09-30. PMID:31680927. |
effects were very consistent: the molecular layer, granule cell layer and polymorphic layer of the dg exhibited higher d2r levels in the ventral compared to dorsal hippocampus. |
2020-09-30 |
2023-08-13 |
Not clear |
| Choong-Hee Lee, Inah Le. Impairment of Pattern Separation of Ambiguous Scenes by Single Units in the CA3 in the Absence of the Dentate Gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 18. 2020-09-30. PMID:32234778. |
theoretical models and experimental evidence have suggested that connections from the dentate gyrus (dg) to ca3 play important roles in representing orthogonal information (i.e., pattern separation) in the hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Domenico Del Turco, Mandy H Paul, Jessica Schlaudraff, Meike Hick, Kristina Endres, Ulrike C Müller, Thomas Delle. Region-Specific Differences in Amyloid Precursor Protein Expression in the Mouse Hippocampus. Frontiers in molecular neuroscience. vol 9. 2020-09-29. PMID:27965537. |
intriguingly, however, studies focusing on the role of app in synaptic plasticity have reported diverging results and considerable differences in effect size between the dentate gyrus (dg) and area ca1 of the mouse hippocampus. |
2020-09-29 |
2023-08-13 |
mouse |
| Eri Segi-Nishid. The Effect of Serotonin-Targeting Antidepressants on Neurogenesis and Neuronal Maturation of the Hippocampus Mediated via 5-HT1A and 5-HT4 Receptors. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:28559799. |
many preclinical studies have suggested that the hippocampus, which contains abundant 5-ht1a and 5-ht4 receptor subtypes in the dentate gyrus (dg), is critically involved in the mechanisms of action of antidepressants. |
2020-09-29 |
2023-08-13 |
Not clear |
| Eri Segi-Nishid. The Effect of Serotonin-Targeting Antidepressants on Neurogenesis and Neuronal Maturation of the Hippocampus Mediated via 5-HT1A and 5-HT4 Receptors. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:28559799. |
despite their limitations, the collective results of these studies describe a potential new mechanism of action, in which 5-ht1a and 5-ht4 receptor signaling, either independently or cooperatively, modulates the function of the hippocampal dg at multiple levels, any of which could play a critical role in the antidepressant actions of 5-ht-enhancing drugs. |
2020-09-29 |
2023-08-13 |
Not clear |
| Wen Liu, Fulton T Crew. Persistent Decreases in Adult Subventricular and Hippocampal Neurogenesis Following Adolescent Intermittent Ethanol Exposure. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:28855864. |
neurogenesis in hippocampal dentate gyrus (dg) and subventricular zone (svz) matures during adolescence to adult levels. |
2020-09-29 |
2023-08-13 |
rat |
| Wen Liu, Fulton T Crew. Persistent Decreases in Adult Subventricular and Hippocampal Neurogenesis Following Adolescent Intermittent Ethanol Exposure. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:28855864. |
in the hippocampus dg, aie exposure increased survival brdu+ cells which differentiated into iba1+ microglia. |
2020-09-29 |
2023-08-13 |
rat |
| Wen Liu, Fulton T Crew. Persistent Decreases in Adult Subventricular and Hippocampal Neurogenesis Following Adolescent Intermittent Ethanol Exposure. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:28855864. |
these data indicate that aie exposure causes a lasting decrease in both adult hippocampal dg and forebrain svz neurogenesis with brain regional differences in the aie response that persist into adulthood. |
2020-09-29 |
2023-08-13 |
rat |
| Yea-Hyun Leem, Morimasa Kato, Hyukki Chan. Regular exercise and creatine supplementation prevent chronic mild stress-induced decrease in hippocampal neurogenesis via Wnt/GSK3β/β-catenin pathway. Journal of exercise nutrition & biochemistry. vol 22. issue 2. 2020-09-29. PMID:30149419. |
therefore, we examined whether regular exercise and/or creatine was closely associated with the activity of the wnt/gsk3β/β-catenin pathway in the hippocampal dg. |
2020-09-29 |
2023-08-13 |
Not clear |
| Filipa Fiel Ferreira, Filipa F Ribeiro, Rui S Rodrigues, Ana Maria Sebastião, Sara Xapell. Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis. Frontiers in cellular neuroscience. vol 12. 2020-09-29. PMID:30546297. |
the adult mammalian brain can produce new neurons in a process called adult neurogenesis, which occurs mainly in the subventricular zone (svz) and in the hippocampal dentate gyrus (dg). |
2020-09-29 |
2023-08-13 |
rat |
| Dragica Selakovic, Jovana Joksimovic, Nemanja Jovicic, Slobodanka Mitrovic, Vladimir Mihailovic, Jelena Katanic, Dragan Milovanovic, Suzana Pantovic, Natasa Mijailovic, Gvozden Rosi. The Impact of Hippocampal Sex Hormones Receptors in Modulation of Depressive-Like Behavior Following Chronic Anabolic Androgenic Steroids and Exercise Protocols in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-09-29. PMID:30792631. |
immunohistochemical analysis showed that exercise reduced ar immunoreactivity in all hippocampal regions and increased the erα expression in the ca1, dentate gyrus (dg), and total hippocampal sections, but not in the ca2/3 region. |
2020-09-29 |
2023-08-13 |
rat |
| Xin Zhang, Zhihong Qiao, Nannan Liu, Lili Gao, Liangpeng Wei, Aili Liu, Zengguang Ma, Feifei Wang, Shaowei Hou, Jisheng Li, Hui She. Stereotypical patterns of epileptiform calcium signal in hippocampal CA1, CA3, dentate gyrus and entorhinal cortex in freely moving mice. Scientific reports. vol 9. issue 1. 2020-09-29. PMID:30872744. |
we observed that ka administration led to one to three kinds of stereotypical patterns of epileptiform calcium activity in ca1, ca3, and dentate gyrus (dg) of the hippocampus, as well as the entorhinal cortex (ec). |
2020-09-29 |
2023-08-13 |
mouse |
| Masayo Ogawa, Daichi Sone, Iman Beheshti, Norihide Maikusa, Kyoji Okita, Harumasa Takano, Hiroshi Matsud. Association between subfield volumes of the medial temporal lobe and cognitive assessments. Heliyon. vol 5. issue 6. 2020-09-29. PMID:31194147. |
compared with normal controls, patients with mci and ad showed subfield volume reductions in cornu ammonis (ca) 1, ca2, brodmann area (ba) 35, ba36, the dentate gyrus (dg), the subiculum, and the entorhinal cortex (erc). |
2020-09-29 |
2023-08-13 |
human |