| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shauna M Stark, C Brock Kirwan, Craig E L Star. Mnemonic Similarity Task: A Tool for Assessing Hippocampal Integrity. Trends in cognitive sciences. vol 23. issue 11. 2020-09-22. PMID:31597601. |
the hippocampus is critical for learning and memory, relying in part on pattern separation processes supported by the dentate gyrus (dg) to prevent interference from overlapping memory representations. |
2020-09-22 |
2023-08-13 |
Not clear |
| Shauna M Stark, C Brock Kirwan, Craig E L Star. Mnemonic Similarity Task: A Tool for Assessing Hippocampal Integrity. Trends in cognitive sciences. vol 23. issue 11. 2020-09-22. PMID:31597601. |
the mst is now a widely used behavioral task, repeatedly shown to be sensitive to age-related memory decline, hippocampal connectivity, and hippocampal function, with specificity to the dg. |
2020-09-22 |
2023-08-13 |
Not clear |
| Shoji Nishida, Ryota Araki, Akihiro Baba, Sota Asari, Shin Tachibana, Yuki Nakajima, Arimi Iwakumo, Takeshi Yab. Post-weaning folate deficiency induces a depression-like state via neuronal immaturity of the dentate gyrus in mice. Journal of pharmacological sciences. vol 143. issue 2. 2020-09-15. PMID:32173264. |
in the dentate gyrus (dg) of the hippocampus, decreased number of newborn mature neurons and increased number of immature neurons were observed in low folate diet-fed mice. |
2020-09-15 |
2023-08-13 |
mouse |
| Zahra Shabani, Javad Mahmoudi, Fereshteh Farajdokht, Saeed Sadigh-Etegha. An Overview of Nicotinic Cholinergic System Signaling in Neurogenesis. Archives of medical research. vol 51. issue 4. 2020-09-15. PMID:32279909. |
the subventricular zone (svz), lining the lateral ventricle, and the subgranular zone (sgz), which is in the dentate gyrus (dg) of the hippocampus, are the central regions of neurogenesis in the brain. |
2020-09-15 |
2023-08-13 |
Not clear |
| Janasha Goffigan-Holmes, Dafne Sanabria, Johana Diaz, Debra Flock, Raul Chavez-Valde. Calbindin-1 Expression in the Hippocampus following Neonatal Hypoxia-Ischemia and Therapeutic Hypothermia and Deficits in Spatial Memory. Developmental neuroscience. 2020-09-12. PMID:30861522. |
in both anterior and posterior coronal brain sections, hippocampal calb1 expression doubled between p11 and p40 due to an increase in the cornus ammonis (ca) field (kruskal-wallis [kw] p < 0.001) and not the dentate gyrus (dg). |
2020-09-12 |
2023-08-13 |
mouse |
| Pascal J D Goetghebeur, Keith A Wesnes, Steven D Targu. D-Cycloserine Improves Difficult Discriminations in a Pattern Separation Task in Alzheimer's Disease Patients with Dementia. Journal of Alzheimer's disease : JAD. vol 69. issue 2. 2020-09-10. PMID:30958353. |
recent fmri studies in human identified that pattern separation ability is associated with increased activity in the hippocampal dentate gyrus (dg), whereas no such dg changes are seen during pattern completion. |
2020-09-10 |
2023-08-13 |
human |
| Runrui Zhang, Marcelo Boareto, Anna Engler, Angeliki Louvi, Claudio Giachino, Dagmar Iber, Verdon Taylo. Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus. Cell reports. vol 28. issue 6. 2020-09-09. PMID:31390563. |
neural stem cells (nscs) in the adult mouse hippocampal dentate gyrus (dg) are mostly quiescent, and only a few are in cell cycle at any point in time. |
2020-09-09 |
2023-08-13 |
mouse |
| Kyung-Ran Kim, Seung Yeon Lee, Sang Ho Yoon, Yoonsub Kim, Hyeon-Ju Jeong, Sanghyeon Lee, Young Ho Suh, Jong-Sun Kang, Hana Cho, Suk-Ho Lee, Myoung-Hwan Kim, Won-Kyung H. Kv4.1, a Key Ion Channel For Low Frequency Firing of Dentate Granule Cells, Is Crucial for Pattern Separation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 11. 2020-09-08. PMID:32047055. |
the dentate gyrus (dg) in the hippocampus may play key roles in remembering distinct episodes through pattern separation, which may be subserved by the sparse firing properties of granule cells (gcs) in the dg. |
2020-09-08 |
2023-08-13 |
mouse |
| Jiuyang Ding, Shanshan Hu, Yunle Meng, Chen Li, Jian Huang, Yitong He, Pingming Qi. Alpha-Synuclein deficiency ameliorates chronic methamphetamine induced neurodegeneration in mice. Toxicology. vol 438. 2020-08-31. PMID:32278788. |
meth increased α-syn level in the stratum oriens, pyramidal layer, stratum radiatum and stratum moleculare of hippocampal ca1, ca2 and ca3, polymorph layer of hippocampal dentate gyrus (dg), and substantia nigra (sn). |
2020-08-31 |
2023-08-13 |
mouse |
| Limin Wang, Zhixiong He, Zhenxiang Zhu, Wei Yuan, Wenqi Cai, Laifu Li, Jing Zhang, Wenjuan Hou, Yang Yang, Xueni Zhang, Qianqian Guo, Xia Wang, Zhenmin Lian, Fadao Ta. The serotonin system in the hippocampus CA3 involves in effects of CSDS on social recognition in adult female mandarin voles (Microtus mandarinus). Progress in neuro-psychopharmacology & biological psychiatry. vol 95. 2020-08-28. PMID:31330217. |
meanwhile, defeated voles exhibited increased neural activity in the dg, ca1 and ca3 of the hippocampus. |
2020-08-28 |
2023-08-13 |
Not clear |
| Tao Xu, Xinyuan Yu, Jing Deng, Shu Ou, Xi Liu, Teng Wang, Ying Liu, Juan Yang, Changhong Tan, Jinxian Yuan, Yangmei Che. CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Cell death & disease. vol 10. issue 11. 2020-08-26. PMID:31672961. |
here, we found that cxcr7 was upregulated in the hippocampal dentate gyrus (dg) of mice subjected to kainic acid (ka)-induced epilepsy and in the brain tissues of patients with temporal lobe epilepsy. |
2020-08-26 |
2023-08-13 |
mouse |
| Tao Xu, Xinyuan Yu, Jing Deng, Shu Ou, Xi Liu, Teng Wang, Ying Liu, Juan Yang, Changhong Tan, Jinxian Yuan, Yangmei Che. CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Cell death & disease. vol 10. issue 11. 2020-08-26. PMID:31672961. |
silencing cxcr7 in the hippocampal dg region exerted an antiepileptic effect on the ka-induced mouse model of epilepsy, whereas cxcr7 overexpression produced a seizure-aggravating effect. |
2020-08-26 |
2023-08-13 |
mouse |
| Yuexiang Wang, Lina Feng, Shikun Liu, Xiaoqing Zhou, Tao Yin, Zhipeng Liu, Zhuo Yan. Transcranial Magneto-Acoustic Stimulation Improves Neuroplasticity in Hippocampus of Parkinson's Disease Model Mice. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 16. issue 4. 2020-08-24. PMID:30993592. |
our results showed that chronic tmas treatment (2 weeks) improved the outcome of morris water maze, long-term potentiation (ltp), and dendritic spine densities in the dentate gyrus (dg) region of the hippocampus of pd model mice. |
2020-08-24 |
2023-08-13 |
mouse |
| Haolin Zhang, Meng Jia, Xue-Wei Wang, Can Ye, Yijing Li, Na Wang, Felice Elefant, Hui Ma, Cailian Cu. Dentate gyrus μ-opioid receptor-mediated neurogenic processes are associated with alterations in morphine self-administration. Scientific reports. vol 9. issue 1. 2020-08-18. PMID:30728362. |
adult hippocampal dentate gyrus (dg) neural stem cells (nscs) continuously undergo proliferation and differentiation, producing new functional neurons that remodel existing synaptic circuits. |
2020-08-18 |
2023-08-13 |
human |
| Liping Xu, Jingyi Long, Zhongqiang Su, Benke Xu, Michael Lin, Yuncai Chen, Dahong Lon. Restored presynaptic synaptophysin and cholinergic inputs contribute to the protective effects of physical running on spatial memory in aged mice. Neurobiology of disease. vol 132. 2020-08-06. PMID:31470103. |
this training strategy improved hippocampal-dependent spatial memory function tested via a novel location task, and enhanced memory was accompanied by restored presynaptic puncta and cholinergic fibers in area ca1 and dg of the hippocampus in old mice. |
2020-08-06 |
2023-08-13 |
mouse |
| Sergi Papiol, Daniel Keeser, Alkomiet Hasan, Thomas Schneider-Axmann, Florian Raabe, Franziska Degenhardt, Moritz J Rossner, Heike Bickeböller, Ludovico Cantuti-Castelvetri, Mikael Simons, Thomas Wobrock, Andrea Schmitt, Berend Malchow, Peter Falka. Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients. Translational psychiatry. vol 9. issue 1. 2020-08-05. PMID:31712617. |
hippocampal volume decrease is a structural hallmark of schizophrenia (scz), and convergent evidence from postmortem and imaging studies suggests that it may be explained by changes in the cytoarchitecture of the cornu ammonis 4 (ca4) and dentate gyrus (dg) subfields. |
2020-08-05 |
2023-08-13 |
Not clear |
| Muhammad Tahir Khan, Jan Deussing, Yong Tang, Peter Ille. Astrocytic rather than neuronal P2X7 receptors modulate the function of the tri-synaptic network in the rodent hippocampus. Brain research bulletin. vol 151. 2020-08-04. PMID:30098388. |
whole-cell patch clamp recordings demonstrated that in the dentate gyrus (dg) as well as in the ca3 area of mouse hippocampal slices the prototypic p2x7 receptor (r) agonist dibenzoyl-atp (bz-atp) induced inward current responses both in neurons and astrocytes. |
2020-08-04 |
2023-08-13 |
mouse |
| Alan Bo Han He, Chung Lei Huang, Anna Kozłowska, Jun Chien Chen, Chi-Wen Wu, Andrew Chih Wei Huang, Yu Qin Li. Involvement of neural substrates in reward and aversion to methamphetamine addiction: Testing the reward comparison hypothesis and the paradoxical effect hypothesis of abused drugs. Neurobiology of learning and memory. vol 166. 2020-07-28. PMID:31521799. |
the c-fos or p-erk immunohistochemical activity showed that the cingulated cortex area 1 (cg1), infralimbic cortex (il), prelimbic cortex (prl), basolateral amygdala (bla), nucleus accumbens (nac), and dentate gyrus (dg) of the hippocampus were overexpressed in aversive cta induced by methamphetamine. |
2020-07-28 |
2023-08-13 |
Not clear |
| Xi Xiao, Xinxin Xu, Fangjuan Li, Guomin Xie, Tao Zhan. Anti-inflammatory treatment with β-asarone improves impairments in social interaction and cognition in MK-801 treated mice. Brain research bulletin. vol 150. 2020-07-24. PMID:31129169. |
extracellular field excitatory postsynaptic potentials were recorded in the hippocampal dentate gyrus (dg) region. |
2020-07-24 |
2023-08-13 |
mouse |
| Xi Xiao, Xinxin Xu, Fangjuan Li, Guomin Xie, Tao Zhan. Anti-inflammatory treatment with β-asarone improves impairments in social interaction and cognition in MK-801 treated mice. Brain research bulletin. vol 150. 2020-07-24. PMID:31129169. |
immunofluorescence was performed to assess the microglial activation in the hippocampus dg region. |
2020-07-24 |
2023-08-13 |
mouse |