| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John J Sakon, Wendy A Suzuk. A neural signature of pattern separation in the monkey hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 19. 2020-03-16. PMID:31010929. |
the ca3 and dentate gyrus (dg) regions of the hippocampus are considered key for disambiguating sensory inputs from similar experiences in memory, a process termed pattern separation. |
2020-03-16 |
2023-08-13 |
monkey |
| Jianguo Li, Jing Chen, Na Ma, Deping Yan, Ying Wang, Xin Zhao, Yu Zhang, Ce Zhan. Effects of corticosterone on the expression of mature brain-derived neurotrophic factor (mBDNF) and proBDNF in the hippocampal dentate gyrus. Behavioural brain research. vol 365. 2020-03-09. PMID:30851317. |
next, using western blot assay, we showed that cort exposure increased the probdnf level in the ventral hippocampal dentate gyrus (dg), decreased the mbdnf level in the dorsal and ventral dg, and decreased the mbdnf/probdnf ratio in the hippocampal dg. |
2020-03-09 |
2023-08-13 |
rat |
| Jianguo Li, Jing Chen, Na Ma, Deping Yan, Ying Wang, Xin Zhao, Yu Zhang, Ce Zhan. Effects of corticosterone on the expression of mature brain-derived neurotrophic factor (mBDNF) and proBDNF in the hippocampal dentate gyrus. Behavioural brain research. vol 365. 2020-03-09. PMID:30851317. |
furthermore, cort administration differentially altered the expression of 11 bdnf mrna transcripts in the dorsal and ventral hippocampal dg. |
2020-03-09 |
2023-08-13 |
rat |
| Yulin Shi, Steven F Grieco, Todd C Holmes, Xiangmin X. Development of Local Circuit Connections to Hilar Mossy Cells in the Mouse Dentate Gyrus. eNeuro. vol 6. issue 2. 2020-03-05. PMID:30937358. |
hilar mossy cells in the dentate gyrus (dg) shape the firing and function of the hippocampal circuit. |
2020-03-05 |
2023-08-13 |
mouse |
| Pauline Bohne, Martin K Schwarz, Stefan Herlitze, Melanie D Mar. A New Projection From the Deep Cerebellar Nuclei to the Hippocampus Frontiers in neural circuits. vol 13. 2020-03-03. PMID:31447652. |
the tracing revealed a direct connection from the dentate gyrus (dg) in the hippocampus to the rsc, rc and subiculum (s), which are monosynaptically connected to thalamic laterodorsal and ventrolateral areas. |
2020-03-03 |
2023-08-13 |
mouse |
| Takahiro Ishimoto, Yusuke Masuo, Yukio Kato, Noritaka Nakamich. Ergothioneine-induced neuronal differentiation is mediated through activation of S6K1 and neurotrophin 4/5-TrkB signaling in murine neural stem cells. Cellular signalling. vol 53. 2020-02-26. PMID:30359715. |
we have previously demonstrated that orally ingested ergothioneine (ergo), a naturally occurring antioxidant and hydrophilic amino acid, promotes neurogenesis in the hippocampal dentate gyrus (dg) with its abundant neural stem cells (nscs) and exerts antidepressant-like effects in mice. |
2020-02-26 |
2023-08-13 |
mouse |
| Sarojini M Attili, Marcos F M Silva, Thuy-Vi Nguyen, Giorgio A Ascol. Cell numbers, distribution, shape, and regional variation throughout the murine hippocampal formation from the adult brain Allen Reference Atlas. Brain structure & function. vol 224. issue 8. 2020-02-24. PMID:31444616. |
while this strategy is directly applicable to any regions of the mouse brain, we first deploy it here on the closed-loop circuit of the hippocampal formation: the medial and lateral entorhinal cortices; dentate gyrus (dg); areas cornu ammonis 3 (ca3), ca2, and ca1; and dorsal and ventral subiculum. |
2020-02-24 |
2023-08-13 |
mouse |
| Haibin Zhang, Hongxuan Kuang, Yifan Luo, Shuhua Liu, Lingxue Meng, Qihua Pang, Ruifang Fa. Low-dose bisphenol A exposure impairs learning and memory ability with alterations of neuromorphology and neurotransmitters in rats. The Science of the total environment. vol 697. 2020-02-20. PMID:31476513. |
additionally, rats after low- or high-exposure to bpa exhibited decreased dg dendritic complexity and reduced ca1 and dg dendritic spine densities in the hippocampus. |
2020-02-20 |
2023-08-13 |
rat |
| Karolina Kołosowska, Aleksandra Gawryluk, Aleksandra Wisłowska-Stanek, Monika Liguz-Lęcznar, Katarzyna Hetmańczyk, Agnieszka Ługowska, Alicja Sobolewska, Anna Skórzewska, Marek Gryz, Małgorzata Lehne. Stress changes amphetamine response, D2 receptor expression and epigenetic regulation in low-anxiety rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 93. 2020-02-14. PMID:31022425. |
the contrasting changes were observed in the dentate gyrus (dg) of the hippocampus - the lr rats presented a decrease, but the hr rats showed an increase in h3k9 trimethylation. |
2020-02-14 |
2023-08-13 |
rat |
| Natalie M Zahr, Kilian M Pohl, Manojkumar Saranathan, Edith V Sullivan, Adolf Pfefferbau. Hippocampal subfield CA2+3 exhibits accelerated aging in Alcohol Use Disorder: A preliminary study. NeuroImage. Clinical. vol 22. 2020-01-17. PMID:30904825. |
freesurfer 6.0 hippocampal subfield analysis produced 12 subfields: parasubiculum; presubiculum; subiculum; ca1; ca2+3; ca4; gc-ml-dg (granule cell (gc) and molecular layer (ml) of the dentate gyrus (dg)); molecular layer; hippocampus-amygdala-transition-area (hata); fimbria; hippocampal tail; hippocampal fissure; and whole volume for left and right hippocampi. |
2020-01-17 |
2023-08-13 |
human |
| Haiyu Mu, Zhifei Wang, Xianjuan Zhang, Dongmeng Qian, Yuyang Wang, Shasha Jiang, Shuzhen Liang, Bin Wan. HCMV-encoded IE2 induces anxiety-depression and cognitive impairment in UL122 genetically-modified mice. International journal of clinical and experimental pathology. vol 12. issue 11. 2020-01-17. PMID:31933804. |
level of fibroblast growth factor 2 (fgf2) protein in the hippocampus cornu ammonia areas (ca1, ca3) and dentate gyrus (dg) of the experimental group was significantly lower, consistent with immunohistochemical staining and western blot for neuron-specific nuclear protein (neun) and glial fibrillary acidic protein (gfap). |
2020-01-17 |
2023-08-13 |
mouse |
| Feixue Wang, Peng Wan, Weiyao Wang, Bin Xiao, Hua Jin, Qinghua Ji. Dopamine in the hippocampal dentate gyrus modulates spatial learning via D1-like receptors. Brain research bulletin. vol 144. 2020-01-16. PMID:30472150. |
as the entry structure of the hippocampal formation, the hippocampal dentate gyrus (dg) is critically involved in spatial learning and memory. |
2020-01-16 |
2023-08-13 |
rat |
| Feixue Wang, Peng Wan, Weiyao Wang, Bin Xiao, Hua Jin, Qinghua Ji. Dopamine in the hippocampal dentate gyrus modulates spatial learning via D1-like receptors. Brain research bulletin. vol 144. 2020-01-16. PMID:30472150. |
our results suggest that da activation of d1rs in the hippocampal dg promotes spatial learning and memory, in part by modulating the responses of eaas during spatial learning. |
2020-01-16 |
2023-08-13 |
rat |
| Barbara Pijet, Marzena Stefaniuk, Leszek Kaczmare. MMP-9 Contributes to Dendritic Spine Remodeling Following Traumatic Brain Injury. Neural plasticity. vol 2019. 2020-01-14. PMID:31198417. |
decreased spine density was also observed in the dentate gyrus of the hippocampus; however, in contrast to the cerebral cortex, spines in the dg became more filopodia-like. |
2020-01-14 |
2023-08-13 |
mouse |
| Wan Long Pan, Michael Chopp, Baoyan Fan, Ruilan Zhang, Xinli Wang, Jiani Hu, Xiao Ming Zhang, Zheng Gang Zhang, Xian Shuang Li. Ablation of the microRNA-17-92 cluster in neural stem cells diminishes adult hippocampal neurogenesis and cognitive function. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 4. 2020-01-13. PMID:30668139. |
compared with wild-type mice, ablation of the mir-17-92 cluster significantly reduced the number of proliferating nscs and neuroblasts and neuronal differentiation in the dentate gyrus (dg) of the hippocampus and significantly impaired hippocampal-dependent learning and memory, as assayed by social recognition memory, novel object recognition, and morris water-maze tests. |
2020-01-13 |
2023-08-13 |
mouse |
| Karim A Alkadh. Cellular and Molecular Differences Between Area CA1 and the Dentate Gyrus of the Hippocampus. Molecular neurobiology. vol 56. issue 9. 2020-01-13. PMID:30874972. |
a distinct feature of the hippocampus of the brain is its unidirectional tri-synaptic pathway originating from the entorhinal cortex and projecting to the dentate gyrus (dg) then to area ca3 and subsequently, area ca1 of the ammon's horn. |
2020-01-13 |
2023-08-13 |
Not clear |
| Bangrong Cai, Kyung-Joo Seong, Sun-Woong Bae, Min Suk Kook, Changju Chun, Jin Ho Lee, Won-Seok Choi, Ji-Yeon Jung, Won-Jae Ki. Water-Soluble Arginyl-Diosgenin Analog Attenuates Hippocampal Neurogenesis Impairment Through Blocking Microglial Activation Underlying NF-κB and JNK MAPK Signaling in Adult Mice Challenged by LPS. Molecular neurobiology. vol 56. issue 9. 2020-01-09. PMID:30740619. |
microglia-mediated neuroinflammatory responses are well known to inhibit neurogenesis in the dentate gyrus (dg) of the adult hippocampus, and growing evidence indicates that therapeutic intervention to suppress microglial activation could be an effective strategy for restoring the impaired neurogenesis and memory performance. |
2020-01-09 |
2023-08-13 |
mouse |
| Bangrong Cai, Kyung-Joo Seong, Sun-Woong Bae, Min Suk Kook, Changju Chun, Jin Ho Lee, Won-Seok Choi, Ji-Yeon Jung, Won-Jae Ki. Water-Soluble Arginyl-Diosgenin Analog Attenuates Hippocampal Neurogenesis Impairment Through Blocking Microglial Activation Underlying NF-κB and JNK MAPK Signaling in Adult Mice Challenged by LPS. Molecular neurobiology. vol 56. issue 9. 2020-01-09. PMID:30740619. |
the impaired neurogenesis in the hippocampal dg triggered the cognitive function, and that treatment of arg-dg led to the recovery of cognitive decline. |
2020-01-09 |
2023-08-13 |
mouse |
| Bangrong Cai, Kyung-Joo Seong, Sun-Woong Bae, Min Suk Kook, Changju Chun, Jin Ho Lee, Won-Seok Choi, Ji-Yeon Jung, Won-Jae Ki. Water-Soluble Arginyl-Diosgenin Analog Attenuates Hippocampal Neurogenesis Impairment Through Blocking Microglial Activation Underlying NF-κB and JNK MAPK Signaling in Adult Mice Challenged by LPS. Molecular neurobiology. vol 56. issue 9. 2020-01-09. PMID:30740619. |
arg-dg also suppressed the production of lps-induced pro-inflammatory cytokines in hippocampal dg by blocking microglial activation. |
2020-01-09 |
2023-08-13 |
mouse |
| Mahshid Hosseinzadeh, Hamid Gholami Pourbadie, Fariba Khodagholi, Mahtab Daftari, Nima Naderi, Fereshteh Motamed. Preconditioning with toll-like receptor agonists attenuates seizure activity and neuronal hyperexcitability in the pilocarpine rat model of epilepsy. Neuroscience. vol 408. 2020-01-09. PMID:31026566. |
24 h after seizure induction, the hippocampal level of pro/anti-inflammatory mediators and electrophysiological properties of the dentate gyrus (dg) granular cells were investigated by western blot and whole cell patch clamp techniques, respectively. |
2020-01-09 |
2023-08-13 |
rat |