| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mary Youssef, Varsha S Krish, Greer S Kirshenbaum, Piray Atsak, Tamara J Lass, Sophie R Lieberman, E David Leonardo, Alex Dranovsk. Ablation of proliferating neural stem cells during early life is sufficient to reduce adult hippocampal neurogenesis. Hippocampus. vol 28. issue 8. 2019-07-16. PMID:29742815. |
environmental exposures during early life, but not during adolescence or adulthood, lead to persistent reductions in neurogenesis in the adult hippocampal dentate gyrus (dg). |
2019-07-16 |
2023-08-13 |
Not clear |
| Mary Youssef, Varsha S Krish, Greer S Kirshenbaum, Piray Atsak, Tamara J Lass, Sophie R Lieberman, E David Leonardo, Alex Dranovsk. Ablation of proliferating neural stem cells during early life is sufficient to reduce adult hippocampal neurogenesis. Hippocampus. vol 28. issue 8. 2019-07-16. PMID:29742815. |
these findings contribute to our understanding of the relationship between dg development and adult neurogenesis, as well as suggest a possible mechanism by which early life experiences may lead to lasting deficits in adult hippocampal neurogenesis. |
2019-07-16 |
2023-08-13 |
Not clear |
| Xiao-Feng Zhao, Rafi Kohen, Rachel Parent, Yuntao Duan, Grace L Fisher, Matthew J Korn, Lingchao Ji, Guoqiang Wan, Jing Jin, Andreas W Püschel, David F Dolan, Jack M Parent, Gabriel Corfas, Geoffrey G Murphy, Roman J Gige. PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors. Cell reports. vol 22. issue 2. 2019-07-15. PMID:29320740. |
dentate gyrus (dg) development requires specification of granule cell (gc) progenitors in the hippocampal neuroepithelium, as well as their proliferation and migration into the primordial dg. |
2019-07-15 |
2023-08-13 |
Not clear |
| Jiali Xu, Yongli Zhang, de Wu, Rui Zho. [Changes and mechanisms of corticosteroid receptors in the subhippocampal region of offspring of pregnant SD rats exposed to lipopolysaccharide]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 34. issue 7. 2019-07-15. PMID:30381125. |
the neurons in the regions of ca1 and dg of the hippocampus were arranged disorderly. |
2019-07-15 |
2023-08-13 |
rat |
| Inmaculada Pereda-Pérez, Azucena Valencia, Shishir Baliyan, Ángel Núñez, Ancor Sanz-García, Berta Zamora, Raquel Rodríguez-Fernández, José Antonio Esteban, César Vener. Systemic administration of a fibroblast growth factor receptor 1 agonist rescues the cognitive deficit in aged socially isolated rats. Neurobiology of aging. vol 78. 2019-07-08. PMID:30928883. |
moreover, isolated animals displayed dampened hippocampal long-term potentiation in vivo, both in the dentate gyrus (dg) and ca1, as well as a specific reduction in the volume of the stratum oriens and spine density in ca1. |
2019-07-08 |
2023-08-13 |
rat |
| Li-Juan Zhu, Huan-Yu Ni, Rong Chen, Lei Chang, Hu-Jiang Shi, Dan Qiu, Zhan Zhang, Dan-Lian Wu, Zhao-Chun Jiang, Hong-Liang Xin, Qi-Gang Zhou, Dong-Ya Zh. Hippocampal nuclear factor kappa B accounts for stress-induced anxiety behaviors via enhancing neuronal nitric oxide synthase (nNOS)-carboxy-terminal PDZ ligand of nNOS-Dexras1 coupling. Journal of neurochemistry. vol 146. issue 5. 2019-06-26. PMID:29858554. |
microinjection of pdtc into the hippocampus reversed cms-induced up-regulation of neuronal nitric oxide synthase (nnos), carboxy-terminal pdz ligand of nnos (capon), and dexamethasone-induced ras protein 1 (dexras1) and dendritic spine loss of dentate gyrus (dg) granule cells. |
2019-06-26 |
2023-08-13 |
mouse |
| Meng Jia, Xuewei Wang, Haolin Zhang, Can Ye, Hui Ma, Mingda Yang, Yijing Li, Cailian Cu. MicroRNA-132 in the Adult Dentate Gyrus is Involved in Opioid Addiction Via Modifying the Differentiation of Neural Stem Cells. Neuroscience bulletin. vol 35. issue 3. 2019-06-26. PMID:30721395. |
similarly, specific overexpression of mir-132 in nscs of the adult hippocampal dentate gyrus (dg) during the acquisition stage of msa potentiated morphine-seeking behavior. |
2019-06-26 |
2023-08-13 |
rat |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
it has been shown that pattern separation specifically relies on the hippocampal dentate gyrus (dg), whereas pattern completion is performed within ca3 networks. |
2019-06-21 |
2023-08-13 |
human |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
in anti-leucine-rich, glioma-inactivated 1 (lgi1) encephalitis it has been shown in animal models and human imaging studies that hippocampal dg and ca3 are preferentially involved in the pathophysiology process. |
2019-06-21 |
2023-08-13 |
human |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
structural sequelae were determined by hippocampal subfield volumetry for the dg, ca1, and ca2/3. |
2019-06-21 |
2023-08-13 |
human |
| Alfonso Diaz, Samuel Treviño, Rubén Vázquez-Roque, Berenice Venegas, Blanca Espinosa, Gonzalo Flores, Juan Manuel Fernández-G, Luis F Montaño, Jorge Guevar. The aminoestrogen prolame increases recognition memory and hippocampal neuronal spine density in aged mice. Synapse (New York, N.Y.). vol 71. issue 10. 2019-06-18. PMID:28545157. |
our aim was to evaluate the effect of prolame on motor and cognitive processes, as well as its influence on the dendritic morphology of neurons at the ca1, ca3, and granule cells of the dentate gyrus (dg) regions of hippocampus (hp), and medium spiny neurons of the nucleus accumbens (nacc) of aged mice. |
2019-06-18 |
2023-08-13 |
mouse |
| Junhua Li, Minyan Guo, Yafang Liu, Guiyun Wu, Liping Miao, Jing Zhang, Zhiyi Zuo, Yujuan L. Both GSK-3β/CRMP2 and CDK5/CRMP2 pathways participate in the protection of dexmedetomidine against propofol-induced learning and memory impairment in neonatal rats. Toxicological sciences : an official journal of the Society of Toxicology. 2019-06-12. PMID:31187143. |
propofol induced apoptosis in the hippocampal neurons and astrocytes, inhibited neuronal proliferation in the dg region, down-regulated the level of γ-aminobutyric acid (gaba) and glutamate in the hippocampus, and impaired long-term cognitive function. |
2019-06-12 |
2023-08-13 |
rat |
| Tirzah Kreisel, Brachi Wolf, Eli Keshet, Tamar Lich. Unique role for dentate gyrus microglia in neuroblast survival and in VEGF-induced activation. Glia. vol 67. issue 4. 2019-06-11. PMID:30453385. |
to examine whether mg residing in the hippocampal neurogenic zone are inherently different from mg residing elsewhere in the hippocampus, we compared growth factor responsiveness of dg mg with that of ca1 mg. |
2019-06-11 |
2023-08-13 |
Not clear |
| Tirzah Kreisel, Brachi Wolf, Eli Keshet, Tamar Lich. Unique role for dentate gyrus microglia in neuroblast survival and in VEGF-induced activation. Glia. vol 67. issue 4. 2019-06-11. PMID:30453385. |
taken together, findings uncover inherent unique properties of dg mg of supporting both basal- and vegf-induced adult hippocampal neurogenesis. |
2019-06-11 |
2023-08-13 |
Not clear |
| Jianqin Yuan, Qi Li, Ruiyan Niu, Jundong Wan. Fluoride exposure decreased learning ability and the expressions of the insulin receptor in male mouse hippocampus and olfactory bulb. Chemosphere. vol 224. 2019-06-10. PMID:30818196. |
irs mainly distributed in the olfactory nerve layer of the outermost layer of the ob, and most distributed in the hippocampal cornu ammon 3 (ca3) region, followed by the dentate gyrus (dg) and cornu ammon 1 (ca1) regions. |
2019-06-10 |
2023-08-13 |
mouse |
| Priyanka Rao-Ruiz, Jonathan J Couey, Ivo M Marcelo, Christian G Bouwkamp, Denise E Slump, Mariana R Matos, Rolinka J van der Loo, Gabriela J Martins, Mirjam van den Hout, Wilfred F van IJcken, Rui M Costa, Michel C van den Oever, Steven A Kushne. Engram-specific transcriptome profiling of contextual memory consolidation. Nature communications. vol 10. issue 1. 2019-06-06. PMID:31110186. |
sparse populations of neurons in the dentate gyrus (dg) of the hippocampus are causally implicated in the encoding of contextual fear memories. |
2019-06-06 |
2023-08-13 |
Not clear |
| Shigeyoshi Saito, Kazuhiko Sawada, Ichio Aok. Prenatal Irradiation-Induced Hippocampal Abnormalities in Rats Evaluated Using Manganese-Enhanced MRI. Frontiers in neural circuits. vol 12. 2019-06-03. PMID:30618648. |
furthermore, glial components consisted largely by astrocytes and minor by microglia were densely distributed in the dg rather than in other hippocampal regions, and their density radiation-exposed rats. |
2019-06-03 |
2023-08-13 |
rat |
| Tomasz Stępień, Sylwia Tarka, Dominik Chutorański, Paulina Felczak, Albert Acewicz, Teresa Wierzba-Bobrowic. Neurogenesis in adult human brain after hemorrhage and ischemic stroke. Folia neuropathologica. vol 56. issue 4. 2019-05-30. PMID:30786666. |
in the adult human brain, two neurogenic regions, the hippocampal dentate gyrus (dg) and the subventricular zone (svz) of lateral ventricles, have been identified. |
2019-05-30 |
2023-08-13 |
human |
| Dong-Hee Choi, In-Ae Choi, Cheol Soon Lee, Ji Hee Yun, Jongmin Le. The Role of NOX4 in Parkinson's Disease with Dementia. International journal of molecular sciences. vol 20. issue 3. 2019-05-29. PMID:30736297. |
in the 6-hydroxydopamine (6-ohda)-injected mouse model, cognitive and motor function, and the levels of α-syn, aβ, and oligomer a11 after inhibition of nox4 expression in the hippocampal dentate gyrus (dg) were measured by the morris water maze, novel object recognition, rotation, and rotarod tests, as well as immunoblotting and immunohistochemistry. |
2019-05-29 |
2023-08-13 |
mouse |
| Dong-Hee Choi, In-Ae Choi, Cheol Soon Lee, Ji Hee Yun, Jongmin Le. The Role of NOX4 in Parkinson's Disease with Dementia. International journal of molecular sciences. vol 20. issue 3. 2019-05-29. PMID:30736297. |
6-ohda dose-dependent cognitive impairment was observed, and the increased cognitive impairment, aβ expression, and oligomer a11 production in 6-ohda-treated mice were suppressed by nox4 knockdown in the hippocampal dg. |
2019-05-29 |
2023-08-13 |
mouse |