| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valentina Zamboni, Maria Armentano, Gabriella Sarò, Elisa Ciraolo, Alessandra Ghigo, Giulia Germena, Alessandro Umbach, Pamela Valnegri, Maria Passafaro, Valentina Carabelli, Daniela Gavello, Veronica Bianchi, Patrizia D'Adamo, Ivan de Curtis, Nadia El-Assawi, Alessandro Mauro, Lorenzo Priano, Nicola Ferri, Emilio Hirsch, Giorgio R Merl. Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits. Scientific reports. vol 6. 2018-08-20. PMID:27713499. |
in the ca3 and dentate gyrus (dg) regions of the arhgap15 mutant hippocampus the cr+, pv+ and sst+ inhibitory neurons are reduced in number, due to reduced efficiency and directionality of their migration, while pyramidal neurons are unaffected. |
2018-08-20 |
2023-08-13 |
Not clear |
| Tatyana N Igonina, Diana S Ragaeva, Maria A Tikhonova, Olga M Petrova, Yuri E Herbeck, Irina N Rozhkova, Tamara G Amstislavskaya, Sergey Ya Amstislavsk. Neurodevelopment and behavior in neonatal OXYS rats with genetically determined accelerated senescence. Brain research. vol 1681. 2018-08-15. PMID:29274882. |
on the sixth day, the neuronal density in oxys pups is reduced in the ca2 hippocampal zone, augmented in ca3 and dg, and unchanged in ca1. |
2018-08-15 |
2023-08-13 |
rat |
| Hannah Maria Jahn, Matteo Bergam. Critical periods regulating the circuit integration of adult-born hippocampal neurons. Cell and tissue research. vol 371. issue 1. 2018-08-10. PMID:28828636. |
neural stem cell-derived new-born neurons emerge to play key functions in the way information is processed in the dg and then conveyed to the ca3 hippocampal area, yet accumulating evidence indicates that both the maturation process and the connectivity pattern of new granule neurons are not prefigured but can be modulated by the activity of local microcircuits and, on a network level, by experience. |
2018-08-10 |
2023-08-13 |
Not clear |
| Yujing Tian, Mengwen Qi, Zhiwen Hong, Yingchun Li, Yibiao Yuan, Yimei Du, Lei Chen, Ling Che. Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus. Molecular neurobiology. vol 54. issue 8. 2018-08-06. PMID:27660267. |
here, we report that intracerebroventricular injection of the trpv4 agonist gsk1016790a for 5 days enhanced the proliferation of stem cells in the hippocampal dentate gyrus (dg) of adult mice without affecting neurite growth, differentiation, or survival of newborn cells. |
2018-08-06 |
2023-08-13 |
mouse |
| Yujing Tian, Mengwen Qi, Zhiwen Hong, Yingchun Li, Yibiao Yuan, Yimei Du, Lei Chen, Ling Che. Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus. Molecular neurobiology. vol 54. issue 8. 2018-08-06. PMID:27660267. |
we conclude that trpv4 activation results in the proliferation of stem cells in the adult hippocampal dg, which is likely mediated through erk1/2 and p38 mapk signaling to increase the expression of cdks (cdk6 and cdk2) and cyclins (cyclin e1 and a2), phosphorylate rb consequently, and accelerate the cell cycle ultimately. |
2018-08-06 |
2023-08-13 |
mouse |
| Zhi-Ping Cao, Dan Dai, Peng-Ju Wei, Yuan-Yuan Han, Yan-Qing Guan, Han-Hang Li, Wen-Xiao Liu, Peng Xiao, Chu-Hua L. Effects of cordycepin on spontaneous alternation behavior and adenosine receptors expression in hippocampus. Physiology & behavior. vol 184. 2018-08-01. PMID:29174913. |
furthermore, cordycepin decreased a2ar density in hippocampal subareas; however, cordycepin only reduced the a1r density in dg but not ca1 or ca3 region. |
2018-08-01 |
2023-08-13 |
mouse |
| Kaori Yagishita, Ritsuko Suzuki, Shota Mizuno, Ritsuko Katoh-Semba, Tetsushi Sadakata, Yoshitake Sano, Teiichi Furuichi, Yo Shinod. CAPS2 deficiency affects environmental enrichment-induced adult neurogenesis and differentiation/survival of newborn neurons in the hippocampal dentate gyrus. Neuroscience letters. vol 661. 2018-07-26. PMID:28963059. |
hippocampal adult neurogenesis is observed in the subgranular zone of the dentate gyrus (dg), and is associated with hippocampal memory formation and several psychiatric disorders including autism spectrum disorder (asd). |
2018-07-26 |
2023-08-13 |
mouse |
| Kaori Yagishita, Ritsuko Suzuki, Shota Mizuno, Ritsuko Katoh-Semba, Tetsushi Sadakata, Yoshitake Sano, Teiichi Furuichi, Yo Shinod. CAPS2 deficiency affects environmental enrichment-induced adult neurogenesis and differentiation/survival of newborn neurons in the hippocampal dentate gyrus. Neuroscience letters. vol 661. 2018-07-26. PMID:28963059. |
calcium-dependent activator protein for secretion 2 (caps2) is a candidate gene related to asd, and is highly expressed in the hippocampal dg region, with caps2 knockout (ko) mice exhibiting asd-like behavior. |
2018-07-26 |
2023-08-13 |
mouse |
| C Rincón-López, A Tlapa-Pale, J-S Medel-Matus, J Martínez-Quiroz, J F Rodríguez-Landa, M-L López-Mera. Interleukin-1β increases neuronal death in the hippocampal dentate gyrus associated with status epilepticus in the developing rat. Neurologia (Barcelona, Spain). vol 32. issue 9. 2018-07-25. PMID:27296494. |
however, it remains uncertain whether il-1β has a similar effect on the hippocampal dentate gyrus (dg). |
2018-07-25 |
2023-08-13 |
rat |
| Azam Sajadi, Iraj Amiri, Alireza Gharebaghi, Alireza Komaki, Masoumeh Asadbegi, Siamak Shahidi, Mehdi Mehdizadeh, Sara Soleimani As. Treadmill exercise alters ecstasy- induced long- term potentiation disruption in the hippocampus of male rats. Metabolic brain disease. vol 32. issue 5. 2018-07-23. PMID:28612273. |
3, 4-methylenedioxymethamphetamine (mdma) or ecstasy is a derivative of amphetamine that leads to long term potentiation (ltp) disruption in the hippocampal dentate gyrus (dg). |
2018-07-23 |
2023-08-13 |
rat |
| Roy Lardenoije, Daniël L A van den Hove, Monique Havermans, Anne van Casteren, Kevin X Le, Roberta Palmour, Cynthia A Lemere, Bart P F Rutte. Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease. Molecular and cellular neurosciences. vol 86. 2018-07-19. PMID:29113959. |
in the j20 mouse model, an age-related decrease in dna methylation was found in the dentate gyrus (dg) and a decrease in the ratio between dna methylation and hydroxymethylation was found in the dg and cornu ammonis (ca) 3. |
2018-07-19 |
2023-08-13 |
mouse |
| Roy Lardenoije, Daniël L A van den Hove, Monique Havermans, Anne van Casteren, Kevin X Le, Roberta Palmour, Cynthia A Lemere, Bart P F Rutte. Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease. Molecular and cellular neurosciences. vol 86. 2018-07-19. PMID:29113959. |
in the j20 model, hippocampal plaque load showed a significant negative correlation with dna methylation in the dg, and with the ratio a negative correlation in the dg and ca3. |
2018-07-19 |
2023-08-13 |
mouse |
| Yuan-Yuan Han, Xiao-Dong Wang, Li Liu, Hong-Mei Guo, Wei Cong, Wen-Wen Yan, Jun-Ni Huang, Peng Xiao, Chu-Hua L. L-type VDCCs participate in behavioral-LTP and memory retention. Neurobiology of learning and memory. vol 145. 2018-07-13. PMID:28866469. |
population spikes (ps) were recorded by using electrophysiological methods to examine the role of verapamil in behavioral ltp in the hippocampal dentate gyrus (dg) region. |
2018-07-13 |
2023-08-13 |
Not clear |
| Yuan-Yuan Han, Xiao-Dong Wang, Li Liu, Hong-Mei Guo, Wei Cong, Wen-Wen Yan, Jun-Ni Huang, Peng Xiao, Chu-Hua L. L-type VDCCs participate in behavioral-LTP and memory retention. Neurobiology of learning and memory. vol 145. 2018-07-13. PMID:28866469. |
electron microscope was used to observe the changes on synaptic ultrastructural morphology in hippocampal dg area. |
2018-07-13 |
2023-08-13 |
Not clear |
| Hye-Yeon Cho, Mujun Kim, Jin-Hee Ha. Specific disruption of contextual memory recall by sparse additional activity in the dentate gyrus. Neurobiology of learning and memory. vol 145. 2018-07-13. PMID:29031808. |
the dentate gyrus (dg) of the hippocampus is essential for contextual and spatial memory processing. |
2018-07-13 |
2023-08-13 |
mouse |
| Yuhui Yan, Liang Kong, Yang Xia, Wenbo Liang, Litong Wang, Jie Song, Yingjia Yao, Ying Lin, Jingxian Yan. Osthole promotes endogenous neural stem cell proliferation and improved neurological function through Notch signaling pathway in mice acute mechanical brain injury. Brain, behavior, and immunity. vol 67. 2018-07-11. PMID:28823624. |
then, using the morris water maze (mwm) test, we revealed that ost significantly improved the learning and memory function in the mbi mice, increased the number of neurons in the regions of brain injury, hippocampus dg and ca3 regions. |
2018-07-11 |
2023-08-13 |
mouse |
| Francis L Pazini, Mauricio P Cunha, Dayane Azevedo, Julia M Rosa, André Colla, Jade de Oliveira, Ana B Ramos-Hryb, Patricia S Brocardo, Joana Gil-Mohapel, Ana Lúcia S Rodrigue. Creatine Prevents Corticosterone-Induced Reduction in Hippocampal Proliferation and Differentiation: Possible Implication for Its Antidepressant Effect. Molecular neurobiology. vol 54. issue 8. 2018-07-09. PMID:27714631. |
these behavioral effects were associated with decreased hippocampal cell proliferation and neuronal differentiation and increased glial fibrillary acid protein (gfap) immunostaining (suggestive of astrogliosis) in dentate gyrus (dg) of the hippocampus. |
2018-07-09 |
2023-08-13 |
mouse |
| Ji Hyeon Ahn, Bai Hui Chen, Bing Chun Yan, Joon Ha Park, Il Jun Kang, Tae-Kyeong Lee, Jeong Hwi Cho, Bich-Na Shin, Jae-Chul Lee, Yong Hwan Jeon, Seongkweon Hong, Young Joo Lee, Soo Young Choi, Moo-Ho Wo. Effects of long‑term scopolamine treatment on cognitive deficits and calcium binding proteins immunoreactivities in the mouse hippocampus. Molecular medicine reports. vol 17. issue 1. 2018-07-09. PMID:29115458. |
cb, cr and pv immunoreactivities distributions were in hippocampal subregions [ca1 and ca3 regions, and the dentate gyrus (dg)]. |
2018-07-09 |
2023-08-13 |
mouse |
| Wei Zhang, Guo-Jun Gu, Qi Zhang, Jian-Hui Liu, Bo Zhang, Yi Guo, Mei-Yun Wang, Qi-Yong Gong, Jian-Rong X. NSCs promote hippocampal neurogenesis, metabolic changes and synaptogenesis in APP/PS1 transgenic mice. Hippocampus. vol 27. issue 12. 2018-07-05. PMID:28833933. |
adult neurogenesis and synaptic remodeling persist as a unique form of structural and functional plasticity in the hippocampal dentate gyrus (dg) and subventricular zone (svz) of the lateral ventricles due to the existence of neural stem cells (nscs). |
2018-07-05 |
2023-08-13 |
mouse |
| Wei Zhang, Guo-Jun Gu, Qi Zhang, Jian-Hui Liu, Bo Zhang, Yi Guo, Mei-Yun Wang, Qi-Yong Gong, Jian-Rong X. NSCs promote hippocampal neurogenesis, metabolic changes and synaptogenesis in APP/PS1 transgenic mice. Hippocampus. vol 27. issue 12. 2018-07-05. PMID:28833933. |
more doublecortin-, brdu/neun- and nestin-positive neurons were observed in the hippocampal dg and svz of the tg-nsc mice. |
2018-07-05 |
2023-08-13 |
mouse |