| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dinesh Upadhya, Bharathi Hattiangady, Olagide W Castro, Bing Shuai, Maheedhar Kodali, Sahithi Attaluri, Adrian Bates, Yi Dong, Su-Chun Zhang, Darwin J Prockop, Ashok K Shett. Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 1. 2019-03-18. PMID:30559206. |
moreover, grafting of hipsc-mge cells after se mediated several neuroprotective and antiepileptogenic effects in the host hippocampus, as evidenced by reductions in host interneuron loss, abnormal neurogenesis, and aberrant mossy fiber sprouting in the dentate gyrus (dg). |
2019-03-18 |
2023-08-13 |
human |
| Dinesh Upadhya, Bharathi Hattiangady, Olagide W Castro, Bing Shuai, Maheedhar Kodali, Sahithi Attaluri, Adrian Bates, Yi Dong, Su-Chun Zhang, Darwin J Prockop, Ashok K Shett. Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 1. 2019-03-18. PMID:30559206. |
furthermore, axons from graft-derived interneurons made synapses on the dendrites of host excitatory neurons in the dg and the ca1 subfield of the hippocampus, implying an excellent graft-host synaptic integration. |
2019-03-18 |
2023-08-13 |
human |
| S Stern, R Santos, M C Marchetto, A P D Mendes, G A Rouleau, S Biesmans, Q-W Wang, J Yao, P Charnay, A G Bang, M Alda, F H Gag. Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium. Molecular psychiatry. vol 23. issue 6. 2019-03-18. PMID:28242870. |
we recently reported that hippocampal dentate gyrus (dg) neurons differentiated from induced pluripotent stem cell (ipsc)-derived fibroblasts of bd patients are electrophysiologically hyperexcitable. |
2019-03-18 |
2023-08-13 |
human |
| A Kanzari, C Bourcier-Lucas, A Freyssin, D N Abrous, N Haddjeri, G Luca. Inducing a long-term potentiation in the dentate gyrus is sufficient to produce rapid antidepressant-like effects. Molecular psychiatry. vol 23. issue 3. 2019-03-12. PMID:28485406. |
recent hypotheses propose that one prerequisite to obtain a rapid antidepressant (ad) effect would reside in processes of synaptic reinforcement occurring within the dentate gyrus (dg) of the hippocampus independently from neurogenesis. |
2019-03-12 |
2023-08-13 |
rat |
| Huan Zhu, Lixing Qiao, Yao Sun, Liping Yin, Li Huang, Li Jiang, Jiaqing L. Basic fibroblast growth factor enhances cell proliferation in the dentate gyrus of neonatal rats following hypoxic-ischemic brain damage. Neuroscience letters. vol 673. 2019-03-11. PMID:29410360. |
the present study aimed to investigate the correlation between neurogenesis and basic fibroblast growth factor (bfgf) in the hippocampal dentate gyrus (dg) region in neonatal rats following hibd. |
2019-03-11 |
2023-08-13 |
rat |
| Rui Zhu, Yi-Hsuan Pan, Lijie Sun, Tianhao Zhang, Caiyun Wang, Shuai Ye, Ning Yang, Tiantian Lu, Thomas Wisniewski, Suying Dang, Wei Zhan. ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice. Neuroscience. vol 399. 2019-03-11. PMID:30579834. |
in this study, we showed that adamts18 mrna is highly abundant in developing brains, especially in the cerebellum granular cell layer and the hippocampus dentate gyrus (dg) granular cell layer. |
2019-03-11 |
2023-08-13 |
mouse |
| Rui Zhu, Yi-Hsuan Pan, Lijie Sun, Tianhao Zhang, Caiyun Wang, Shuai Ye, Ning Yang, Tiantian Lu, Thomas Wisniewski, Suying Dang, Wei Zhan. ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice. Neuroscience. vol 399. 2019-03-11. PMID:30579834. |
adamts18 knockout (ko) mice displayed higher dendritic branching complexity and spine density on hippocampal dg granular cells. |
2019-03-11 |
2023-08-13 |
mouse |
| A Dheer, V Jain, N Kushwah, R Kumar, D Prasad, S B Sing. Temporal and Spatial Changes in Glial Cells During Chronic Hypobaric Hypoxia: Role in Neurodegeneration. Neuroscience. vol 383. 2019-03-07. PMID:29751055. |
the study aims to understand the effect of hh exposure on glial physiology in a time-dependent (0, 1, 3, 7 and 14 days of hh exposure) and region-dependent (ca1, ca3 and dg regions of hippocampus) manner. |
2019-03-07 |
2023-08-13 |
Not clear |
| Randa Kassab, Frédéric Alexandr. Pattern separation in the hippocampus: distinct circuits under different conditions. Brain structure & function. vol 223. issue 6. 2019-02-28. PMID:29637298. |
pattern separation is a fundamental hippocampal process thought to be critical for distinguishing similar episodic memories, and has long been recognized as a natural function of the dentate gyrus (dg), supporting autoassociative learning in ca3. |
2019-02-28 |
2023-08-13 |
Not clear |
| Yoshio Takashima, McKenzie J Fannon, Melissa H Galinato, Noah L Steiner, Michelle An, Alice E Zemljic-Harpf, Sucharita S Somkuwar, Brian P Head, Chitra D Mandya. Neuroadaptations in the dentate gyrus following contextual cued reinstatement of methamphetamine seeking. Brain structure & function. vol 223. issue 5. 2019-02-27. PMID:29441405. |
the current study tested the hypothesis that alterations in the functional properties of granule cell neurons (gcns) in the dentate gyrus (dg) of the hippocampus in concert with altered expression of synaptic plasticity-related proteins and ultrastructural changes in the dg are associated with enhanced context-driven methamphetamine-seeking behavior. |
2019-02-27 |
2023-08-13 |
rat |
| Sonu Singh, Akanksha Mishra, Sachi Bharti, Virendra Tiwari, Jitendra Singh, Parul, Shubha Shukl. Glycogen Synthase Kinase-3β Regulates Equilibrium Between Neurogenesis and Gliogenesis in Rat Model of Parkinson's Disease: a Crosstalk with Wnt and Notch Signaling. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29327199. |
herein, we show that single intra-medial forebrain bundle (mfb) injection of 6-hydroxydopamine (6-ohda) efficiently induced long-term activation of gsk-3β and reduced nsc self-renewal, proliferation, neuronal migration, and neuronal differentiation accompanied with increased astrogenesis in subventricular zone (svz) and hippocampal dentate gyrus (dg). |
2019-02-26 |
2023-08-13 |
rat |
| McKenzie J Fannon, Karthik K Mysore, Jefferson Williams, Leon W Quach, Dvijen C Purohit, Britta D Sibley, Janna S Sage-Sepulveda, Khush M Kharidia, Roberto J Morales Silva, Michael J Terranova, Sucharita S Somkuwar, Miranda C Staples, Chitra D Mandya. Hippocampal neural progenitor cells play a distinct role in fear memory retrieval in male and female CIE rats. Neuropharmacology. vol 143. 2019-02-25. PMID:30273595. |
these data suggest that dg npcs born during withdrawal and early abstinence from cie are aberrant, and could play a role in weakening long-term memory consolidation dependent on the hippocampus. |
2019-02-25 |
2023-08-13 |
rat |
| Nuno D Alves, Patrícia Patrício, Joana S Correia, António Mateus-Pinheiro, Ana R Machado-Santos, Eduardo Loureiro-Campos, Mónica Morais, João M Bessa, Nuno Sousa, Luísa Pint. Chronic stress targets adult neurogenesis preferentially in the suprapyramidal blade of the rat dorsal dentate gyrus. Brain structure & function. vol 223. issue 1. 2019-02-22. PMID:28852856. |
the continuous generation of new neurons and glial cells in the adult hippocampal dentate gyrus (dg) represents an important form of adult neuroplasticity, involved in normal brain function and behavior but also associated with the etiopathogenesis and treatment of psychiatric disorders. |
2019-02-22 |
2023-08-13 |
rat |
| J Harry Blaise, Jee E Park, Nicholas J Bellas, Thomas M Gitchell, Vy Pha. Caffeine consumption disrupts hippocampal long-term potentiation in freely behaving rats. Physiological reports. vol 6. issue 5. 2019-02-21. PMID:29512310. |
stimulating and recording electrodes were chronically implanted in the perforant pathway (pp) and dentate gyrus (dg) region of the hippocampus, respectively, to permit stable electrophysiological recordings of synaptic transmission at this synapse. |
2019-02-21 |
2023-08-13 |
rat |
| Elane N Magn. Proliferative hippocampal activity in a group of patients with Rasmussen's encephalitis: Neuronal, glial, and BDNF tissue expression correlations. Epilepsy & behavior : E&B. vol 82. 2019-02-21. PMID:29579552. |
these results suggest a proliferation activity in the dg subfield of patients with re, and also future studies are necessary to address the role of new cells in the hippocampus of patients with re. |
2019-02-21 |
2023-08-13 |
human |
| Anna Beroun, Maria Nalberczak-Skóra, Zofia Harda, Małgorzata Piechota, Magdalena Ziółkowska, Anna Cały, Roberto Pagano, Kasia Radwansk. Generation of silent synapses in dentate gyrus correlates with development of alcohol addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 10. 2019-02-21. PMID:29967367. |
here we focus on hippocampal circuitry and show that chemogenetic inhibition of dentate gyrus (dg) during presentation of alcohol-associated cues has long-lasting effects on mice behavior. |
2019-02-21 |
2023-08-13 |
mouse |
| Muhammad Tahir Khan, Juan Liu, Jana Nerlich, Yong Tang, Heike Franke, Peter Ille. Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus. Neuropharmacology. vol 140. 2019-02-20. PMID:30092245. |
patch-clamp recordings from dentate gyrus (dg) granule cells in acutely prepared hippocampal slices of mice showed that incubation with 4-aminopyridine (4-ap) causes an excitability increase. |
2019-02-20 |
2023-08-13 |
mouse |
| b' Rita Soares, Filipa F Ribeiro, Sara Xapelli, T\\xc3\\xa2nia Genebra, Maria F Ribeiro, Ana M Sebasti\\xc3\\xa3o, Cec\\xc3\\xadlia M P Rodrigues, Susana Sol\\xc3\\xa. Tauroursodeoxycholic Acid Enhances Mitochondrial Biogenesis, Neural Stem Cell Pool, and Early Neurogenesis in Adult Rats. Molecular neurobiology. vol 55. issue 5. 2019-02-18. PMID:28534273.' |
in the present study, we explore the effect of tudca on regulation of nsc fate in neurogenic niches, the subventricular zone (svz) of the lateral ventricles and the hippocampal dentate gyrus (dg), using rat postnatal neurospheres and adult rats exposed to the bile acid. |
2019-02-18 |
2023-08-13 |
rat |
| Carine Nguemeni, Matthew W McDonald, Matthew S Jeffers, Jessica Livingston-Thomas, Diane Lagace, Dale Corbet. Short- and Long-term Exposure to Low and High Dose Running Produce Differential Effects on Hippocampal Neurogenesis. Neuroscience. vol 369. 2019-02-18. PMID:29175485. |
continuous running wheel (rw) exercise increases adult hippocampal neurogenesis in the dentate gyrus (dg) of rodents. |
2019-02-18 |
2023-08-13 |
human |
| Jianan Li, Xueting Li, Haoran Bi, Baixiang L. The MEK/ERK/CREB signaling pathway is involved in atrazine induced hippocampal neurotoxicity in Sprague Dawley rats. Ecotoxicology and environmental safety. vol 170. 2019-02-15. PMID:30580161. |
moreover, analysis by electron microscopy showed that hippocampal neuron ultrastructure in the dentate gyrus (dg) and cornu ammonis 1 (ca1) sub-regions was impaired in the atr-treated groups. |
2019-02-15 |
2023-08-13 |
human |