| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Monica M Davis, Sandra L O'Keefe, David A Primrose, Ross B Hodgett. A neuropeptide hormone cascade controls the precise onset of post-eclosion cuticular tanning in Drosophila melanogaster. Development (Cambridge, England). vol 134. issue 24. 2008-02-20. PMID:18003740. |
together, two enzymes, tyrosine hydroxylase (th, encoded by ple) and dopa decarboxylase (ddc, encoded by ddc), produce the dopamine that is required for tanning. |
2008-02-20 |
2023-08-12 |
drosophila_melanogaster |
| Katherine W Jordan, Theodore J Morgan, Trudy F C Macka. Quantitative trait loci for locomotor behavior in Drosophila melanogaster. Genetics. vol 174. issue 1. 2006-12-18. PMID:16783013. |
we used complementation tests of deficiencies to fine map these qtl to 12 chromosomal regions and complementation tests of mutations to identify 13 positional candidate genes affecting locomotor reactivity, including dopa decarboxylase (ddc), which catalyzes the final step in the synthesis of serotonin and dopamine. |
2006-12-18 |
2023-08-12 |
human |
| Ross B Hodgetts, Sandra L O'Keef. Dopa decarboxylase: a model gene-enzyme system for studying development, behavior, and systematics. Annual review of entomology. vol 51. 2006-08-03. PMID:16332212. |
the enzyme (ddc) catalyzes the production of the neural transmitters dopamine and serotonin. |
2006-08-03 |
2023-08-12 |
Not clear |
| Jill L Smith, Pankaj B Patil, Shelley D Minteer, Jason R Lipsitz, Jonathan S Fishe. Possibility of autocrine beta-adrenergic signaling in C2C12 myotubes. Experimental biology and medicine (Maywood, N.J.). vol 230. issue 11. 2006-02-16. PMID:16339749. |
the decrease in insulin-stimulated glucose transport caused by levodopa was attenuated by propranolol (a beta-adrenergic antagonist) and prevented by nsd-1015 (nsd), an inhibitor of dopa decarboxylase (ddc; converts levodopa to dopamine). |
2006-02-16 |
2023-08-12 |
Not clear |
| Trudy F Mackay, Richard F Lyma. Drosophila bristles and the nature of quantitative genetic variation. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 360. issue 1459. 2005-11-21. PMID:16108138. |
dopa decarboxylase (ddc) encodes the enzyme that catalyses the final step in the synthesis of dopamine, a major drosophila catecholamine and neurotransmitter. |
2005-11-21 |
2023-08-12 |
drosophila_melanogaster |
| Jennie Z Ma, Joke Beuten, Thomas J Payne, Randolph T Dupont, Robert C Elston, Ming D L. Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence. Human molecular genetics. vol 14. issue 12. 2005-09-13. PMID:15879433. |
dopa decarboxylase (ddc; also known as l-amino acid decarboxylase; aadc) is involved in the synthesis of dopamine, norepinephrine and serotonin. |
2005-09-13 |
2023-08-12 |
Not clear |
| C-Y Huang, S-Y Chou, L C Bartholomay, B M Christensen, C-C Che. The use of gene silencing to study the role of dopa decarboxylase in mosquito melanization reactions. Insect molecular biology. vol 14. issue 3. 2005-07-08. PMID:15926892. |
mosquito melanization involves hydroxylation of tyrosine to dopa, which then is oxidized to dopaquinone by phenoloxidase, or decarboxylated to dopamine by dopa decarboxlase (ddc). |
2005-07-08 |
2023-08-12 |
Not clear |
| Iu V Vakhitova, R S Iamidanov, S B Seredini. [Ladasten induces the expression of genes regulating dopamine biosynthesis in various structures of rat brain]. Eksperimental'naia i klinicheskaia farmakologiia. vol 67. issue 4. 2005-03-31. PMID:15500036. |
the effect of ladasten (50 mg/kg) on the activity of tyrosine hydrolase (th) and dopa-decarboxylase (ddc) gene expression and on the content of dopamine and l-dopa in the striatum and hypothalamus in rat brain was studied depending on the duration of drug action. |
2005-03-31 |
2023-08-12 |
rat |
| Boyu Zhang, Yanbin Jia, Yanbo Yuan, Xin Yu, Qi Xu, Yucun Shen, Yan She. No association between polymorphisms in the DDC gene and paranoid schizophrenia in a northern Chinese population. Psychiatric genetics. vol 14. issue 3. 2005-03-07. PMID:15318031. |
dopa decarboxylase (ddc) is an enzyme involved directly in the synthesis of dopamine and serotonin, and indirectly in the synthesis of noradrenaline. |
2005-03-07 |
2023-08-12 |
Not clear |
| Fabio Bozzi, Roberto Luksch, Paola Collini, Felicita Gambirasio, Elena Barzanò, Daniela Polastri, Marta Podda, Bruno Brando, Franca Fossati-Bellan. Molecular detection of dopamine decarboxylase expression by means of reverse transcriptase and polymerase chain reaction in bone marrow and peripheral blood: utility as a tumor marker for neuroblastoma. Diagnostic molecular pathology : the American journal of surgical pathology, part B. vol 13. issue 3. 2005-02-01. PMID:15322424. |
a highly sensitive molecular method was used to evaluate the presence of dopamine decarboxylase (ddc) mrna in the bone marrow and peripheral blood of patients with neuroblastoma (nb). |
2005-02-01 |
2023-08-12 |
Not clear |
| C Sakakura, M Takemura, A Hagiwara, K Shimomura, K Miyagawa, S Nakashima, T Yoshikawa, T Takagi, S Kin, Y Nakase, J Fujiyama, Y Hayasizaki, Y Okazaki, H Yamagish. Overexpression of dopa decarboxylase in peritoneal dissemination of gastric cancer and its potential as a novel marker for the detection of peritoneal micrometastases with real-time RT-PCR. British journal of cancer. vol 90. issue 3. 2004-03-12. PMID:14760382. |
one of the upregulated genes is dopa decarboxylase (ddc), which is responsible for the synthesis of the key neurotransmitters dopamine and serotonine. |
2004-03-12 |
2023-08-12 |
Not clear |
| K Takahata, S Shimazu, F Yoneda, M Ogawa, Y Iida, H Saj. Effects of monoamine oxidase inhibitors on the diethyldithiocarbamate-induced enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in C57BL/6 mice. Journal of neural transmission (Vienna, Austria : 1996). vol 110. issue 8. 2004-02-19. PMID:12898342. |
the aims of the present study were to provide biochemical, pathological and behavioral evidence for the degeneration of dopamine (da) neurons in c57bl/6 strain mice treated simultaneously with ddc and mptp, and to evaluate the effects of monoamine oxidase (mao) inhibitors on ddc-enhanced mptp toxicity. |
2004-02-19 |
2023-08-12 |
mouse |
| A D Børglum, G Kirov, N Craddock, O Mors, W Muir, V Murray, I McKee, D A Collier, H Ewald, M J Owen, D Blackwood, T A Krus. Possible parent-of-origin effect of Dopa decarboxylase in susceptibility to bipolar affective disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 117B. issue 1. 2003-11-06. PMID:12555230. |
dopa decarboxylase (ddc) catalyses the synthesis of both dopamine and serotonin as well as trace amines suggested to possess neuromodulating capabilities. |
2003-11-06 |
2023-08-12 |
human |
| Maria De Luca, Nataliya V Roshina, Gretchen L Geiger-Thornsberry, Richard F Lyman, Elena G Pasyukova, Trudy F C Macka. Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. Nature genetics. vol 34. issue 4. 2003-09-22. PMID:12881721. |
ddc catalyzes the final step in the synthesis of the neurotransmitters, dopamine and serotonin. |
2003-09-22 |
2023-08-12 |
drosophila_melanogaster |
| Regina C C Kubrusly, Marília Zaluar P Guimarães, Ana Paula B Vieira, Jan N Hokoç, Dulce E Casarini, Maria C F de Mello, Fernando G de Mell. L-DOPA supply to the neuro retina activates dopaminergic communication at the early stages of embryonic development. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807423. |
the dopamine (da) content of e9/10 and e15/16 retinas, pre-incubated with l-dopa for 1 h, increased 250- and 600-fold, respectively, showing that ddc is active since early in development. |
2003-08-26 |
2023-08-12 |
chicken |
| Maria-Zaharenia Siaterli, Dido Vassilacopoulou, Emmanuel G Fragouli. Cloning and expression of human placental L-Dopa decarboxylase. Neurochemical research. vol 28. issue 6. 2003-07-08. PMID:12718431. |
l-dopa decarboxylase (ddc) is a pyridoxal 5-phosphate (plp)-dependent enzyme that catalyses the decarboxylation of l-dopa to dopamine. |
2003-07-08 |
2023-08-12 |
human |
| Mariarita Bertoldi, Carla Borri Voltattorn. Reaction and substrate specificity of recombinant pig kidney Dopa decarboxylase under aerobic and anaerobic conditions. Biochimica et biophysica acta. vol 1647. issue 1-2. 2003-06-05. PMID:12686106. |
dopa decarboxylase (ddc) catalyzes as main reaction the stereospecific co(2) abstraction from l-dopa and l-5-hydroxytryptophan (5-htp), generating the corresponding aromatic amines, dopamine and serotonin, respectively. |
2003-06-05 |
2023-08-12 |
cat |
| H Noguchi, S Tsuzuki, K Tanaka, H Matsumoto, K Hiruma, Y Hayakaw. Isolation and characterization of a dopa decarboxylase cDNA and the induction of its expression by an insect cytokine, growth-blocking peptide in Pseudaletia separata. Insect biochemistry and molecular biology. vol 33. issue 2. 2003-04-17. PMID:12535679. |
dopa decarboxylase (ddc) converts dopa to dopamine, and its cdna was isolated from p. separata, and the deduced amino acid sequence showed that it was highly homologous to other lepidopteran ddcs, showing 96, 90 and 86% identity with those of mamestra brassicae, bombyx mori, and manduca sexta, respectively. |
2003-04-17 |
2023-08-12 |
Not clear |
| Esther Jahnes, Daniel J Müller, Thomas G Schulze, Christine Windemuth, Sven Cichon, Stephanie Ohlraun, Heiner Fangerau, Tilo Held, Wolfgang Maier, Peter Propping, Markus M Nöthen, Marcella Rietsche. Association study between two variants in the DOPA decarboxylase gene in bipolar and unipolar affective disorder. American journal of medical genetics. vol 114. issue 5. 2002-10-01. PMID:12116187. |
dopa decarboxylase (ddc), also known as aromatic l-amino acid decarboxylase, is an enzyme involved directly in the synthesis of dopamine and serotonin and indirectly in the synthesis of noradrenaline. |
2002-10-01 |
2023-08-12 |
human |
| P Burkhard, P Dominici, C Borri-Voltattorni, J N Jansonius, V N Malashkevic. Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase. Nature structural biology. vol 8. issue 11. 2001-12-04. PMID:11685243. |
dopa decarboxylase (ddc) is responsible for the synthesis of the key neurotransmitters dopamine and serotonin via decarboxylation of l-3,4-dihydroxyphenylalanine (l-dopa) and l-5-hydroxytryptophan, respectively. |
2001-12-04 |
2023-08-12 |
Not clear |