| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A K M H Kober, M Aoyama, S Sugit. Immunohistochemical localization of catecholamine biosynthetic enzymes in the adrenal gland of the domestic fowl (Gallus domesticus). Poultry science. vol 89. issue 8. 2010-12-03. PMID:20634527. |
the present study investigated the cellular localization of 3 catecholamine biosynthetic enzymes, tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine n-methyltransferase (pnmt) to identify and analyze the localization of norepinephrine (ne) and epinephrine (e) cells in the adrenal gland in the chicken using peroxidase-antiperoxidase immunohistochemical techniques. |
2010-12-03 |
2023-08-12 |
chicken |
| Nipa Bhaduri, Kanyakumarika Sarkar, Swagata Sinha, Anindita Chattopadhyay, Kanchan Mukhopadhya. Study on DBH genetic polymorphisms and plasma activity in attention deficit hyperactivity disorder patients from Eastern India. Cellular and molecular neurobiology. vol 30. issue 2. 2010-10-06. PMID:19757024. |
synthesis of norepinephrine from dopamine is catalyzed by the enzyme dopamine beta-hydroxylase and numerous polymorphisms in the dbh gene have been found to exert their direct influence on the enzyme activity independently. |
2010-10-06 |
2023-08-12 |
human |
| Surekha Rani Panjala, Steven A Thomas, Jena J Steinl. Effects of insulin-like growth factor-1 (IGF-1) receptor signaling on rates of apoptosis in retina of dopamine beta hydroxylase (Dbh-/-) knockout mice. Autonomic neuroscience : basic & clinical. vol 152. issue 1-2. 2010-04-29. PMID:19748322. |
retinal lysates from dbh(-/-) and their heterozygote littermates (dbh(+/-)) were used to examine the role of norepinephrine in the regulation of igf-1 receptor signaling and apoptosis in the retina. |
2010-04-29 |
2023-08-12 |
mouse |
| Yuqing Chen, Gen Wen, Fangwen Rao, Kuixing Zhang, Lei Wang, Juan L Rodriguez-Flores, Amber P Sanchez, Manjula Mahata, Laurent Taupenot, Ping Sun, Sushil K Mahata, Bamidele Tayo, Nicholas J Schork, Michael G Ziegler, Bruce A Hamilton, Daniel T O'Conno. Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure. Journal of hypertension. vol 28. issue 1. 2010-03-09. PMID:20009769. |
dopamine beta-hydroxylase (dbh) plays an essential role in catecholamine synthesis by converting dopamine into norepinephrine. |
2010-03-09 |
2023-08-12 |
human |
| Sudhirkumar U Yanpallewar, Kimberly Fernandes, Swananda V Marathe, Krishna C Vadodaria, Dhanisha Jhaveri, Karen Rommelfanger, Uma Ladiwala, Shanker Jha, Verena Muthig, Lutz Hein, Perry Bartlett, David Weinshenker, Vidita A Vaidy. Alpha2-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 3. 2010-02-05. PMID:20089918. |
these effects persist in dopamine beta-hydroxylase knock-out (dbh(-/-)) mice lacking norepinephrine, supporting a role for alpha(2)-heteroceptors on progenitor cells, rather than alpha(2)-autoreceptors on noradrenergic neurons that inhibit norepinephrine release. |
2010-02-05 |
2023-08-12 |
mouse |
| Ljubica Gavrilovic, Natasa Spasojevic, Sladjana Dronja. Psychosocial stress-related changes in gene expression of norepinephrine biosynthetic enzymes in stellate ganglia of adult rats. Autonomic neuroscience : basic & clinical. vol 150. issue 1-2. 2009-11-16. PMID:19482560. |
in this study we investigated the changes in norepinephrine biosynthetic enzymes tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh) and phenylethanolamine n-methyltransferase (pnmt) gene expression in the stellate ganglia of naive controls and long-term socially isolated (12 weeks) adult rats and the response of these animals to additional immobilization stress. |
2009-11-16 |
2023-08-12 |
rat |
| Mitsuhiro Kamata, Akihito Suzuki, Yoshihiko Matsumoto, Naoshi Shibuya, Hitoshi Togashi, Kaoru Goto, Koichi Otan. Association study between the -1021C/T polymorphism of the dopamine-beta-hydroxylase gene promoter and personality traits in healthy subjects. Neuroscience letters. vol 462. issue 1. 2009-10-07. PMID:19560519. |
dopamine-beta-hydroxylase (dbh) is the enzyme responsible for conversion of dopamine to norepinephrine, and thus plays an important role in controlling dispositions of these neurotransmitters. |
2009-10-07 |
2023-08-12 |
human |
| Yan Fan, Jingjing Huang, Niamh Kieran, Meng-Yang Zh. Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells. Journal of neurochemistry. vol 110. issue 5. 2009-09-21. PMID:19573018. |
in the present study, we examined the possible effect of phox2a/2b on the in vitro expression of the norepinephrine transporter (net) and dopamine beta-hydroxylase (dbh), two important markers of the noradrenergic system. |
2009-09-21 |
2023-08-12 |
human |
| Yan Fan, Jingjing Huang, Niamh Kieran, Meng-Yang Zh. Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells. Journal of neurochemistry. vol 110. issue 5. 2009-09-21. PMID:19573018. |
transfection of shrnas specific to phox2a or phox2b genes significantly reduced mrna and protein levels of net and dbh after shutdown of endogenous phox2, which was accompanied by a decreased [(3)h]norepinephrine uptake. |
2009-09-21 |
2023-08-12 |
human |
| David S Goldstein, Courtney S Holmes, Stephen G Kale. Relative efficiencies of plasma catechol levels and ratios for neonatal diagnosis of menkes disease. Neurochemical research. vol 34. issue 8. 2009-08-20. PMID:19234788. |
menkes disease can be detected by relatively high concentrations of dopamine (da) and its metabolites compared to norepinephrine (ne) and its metabolites, presumably because dopamine-beta-hydroxylase (dbh) requires copper as a co-factor. |
2009-08-20 |
2023-08-12 |
Not clear |
| Patrick Slama, Jean-Luc Boucher, Marius Réglie. N-Hydroxyguanidines oxidation by a N3S copper-complex mimicking the reactivity of Dopamine beta-Hydroxylase. Journal of inorganic biochemistry. vol 103. issue 3. 2009-04-10. PMID:19178946. |
dbh catalyses the hydroxylation of the important neurotransmitter dopamine into norepinephrine in the presence of both molecular oxygen and a reducing co-substrate. |
2009-04-10 |
2023-08-12 |
Not clear |
| Steven J Swoap, David Weinshenke. Norepinephrine controls both torpor initiation and emergence via distinct mechanisms in the mouse. PloS one. vol 3. issue 12. 2009-02-19. PMID:19107190. |
we previously showed that dopamine beta-hydroxylase knockout (dbh -/-) mice, which lack norepinephrine (ne), do not reduce circulating leptin upon fasting nor do they enter torpor. |
2009-02-19 |
2023-08-12 |
mouse |
| b' Patricia Patterson-Buckendahl, Larissa A Pohorecky, Lucia Kubovcakova, Olga Krizanova, R Bruce Martin, Daniel A Martinez, Richard Kvetnansk\\xc3\\xb. Ethanol and stress activate catecholamine synthesis in the adrenal: effects on bone. Annals of the New York Academy of Sciences. vol 1148. 2009-01-23. PMID:19120155.' |
femoral yield load, displacement, and work at yield load were negatively correlated with th and dbh mrna levels, but not pnmt, suggesting a negative influence of norepinephrine. |
2009-01-23 |
2023-08-12 |
rat |
| J L Hoard, D B Hoover, A M Mabe, R D Blakely, N Feng, N Paolocc. Cholinergic neurons of mouse intrinsic cardiac ganglia contain noradrenergic enzymes, norepinephrine transporters, and the neurotrophin receptors tropomyosin-related kinase A and p75. Neuroscience. vol 156. issue 1. 2009-01-05. PMID:18674600. |
dopamine beta-hydroxylase (dbh) and norepinephrine transporter (net) were present in all cholinergic somata, indicating a wider capability for dopamine metabolism and catecholamine uptake. |
2009-01-05 |
2023-08-12 |
mouse |
| Sarah A Heimovics, Lauren V Riter. Evidence that dopamine within motivation and song control brain regions regulates birdsong context-dependently. Physiology & behavior. vol 95. issue 1-2. 2008-12-18. PMID:18619478. |
immunocytochemistry for dopamine beta-hydroxylase (dbh; the enzyme that converts da to norepinephrine) was also performed to provide insight into whether relationships between song and th immunoreactivity reflected dopaminergic or noradrenergic neurotransmission. |
2008-12-18 |
2023-08-12 |
Not clear |
| Meriem Gaval-Cruz, Jason P Schroeder, L Cameron Liles, Martin A Javors, David Weinshenke. Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures. Pharmacology, biochemistry, and behavior. vol 89. issue 4. 2008-08-06. PMID:18329701. |
the antialcoholism drug disulfiram has shown recent promise as a pharmacotherapy for treating cocaine dependence, probably via inhibition of dopamine beta-hydroxylase (dbh), the enzyme that catalyzes the conversion of dopamine (da) to norepinephrine (ne). |
2008-08-06 |
2023-08-12 |
mouse |
| Mads Togsverd, Thomas M Werge, Laszlo B Tankó, Yu Z Bagger, George G Qin, Thomas Hansen, Claus Christiansen, Henrik B Rasmusse. Cognitive performance in elderly women: significance of the 19bp insertion/deletion polymorphism in the 5' flank of the dopamine beta-hydroxylase gene, educational level, body fat measures, serum triglyceride, alcohol consumption and age. International journal of geriatric psychiatry. vol 22. issue 9. 2008-05-01. PMID:17200925. |
the gene encoding dopamine beta-hydroxylase (dbh) could be one such factor since this hydroxylase converts dopamine to norepinephrine both of which are involved in cognition regulation. |
2008-05-01 |
2023-08-12 |
Not clear |
| Emily M Garland, Bonnie K Black, Paul A Harris, David Robertso. Dopamine-beta-hydroxylase in postural tachycardia syndrome. American journal of physiology. Heart and circulatory physiology. vol 293. issue 1. 2007-09-12. PMID:17625104. |
norepinephrine is synthesized from dopamine by dopamine-beta-hydroxylase (dbh). |
2007-09-12 |
2023-08-12 |
human |
| Emily M Garland, Bonnie K Black, Paul A Harris, David Robertso. Dopamine-beta-hydroxylase in postural tachycardia syndrome. American journal of physiology. Heart and circulatory physiology. vol 293. issue 1. 2007-09-12. PMID:17625104. |
to test the hypothesis that low dbh activity and the underlying -1021c-->t polymorphism are associated with increased susceptibility to pots, we measured serum dbh activity in pots and determined its relationship to the dbh genotype and plasma norepinephrine. |
2007-09-12 |
2023-08-12 |
human |
| Emily M Garland, Bonnie K Black, Paul A Harris, David Robertso. Dopamine-beta-hydroxylase in postural tachycardia syndrome. American journal of physiology. Heart and circulatory physiology. vol 293. issue 1. 2007-09-12. PMID:17625104. |
high dbh in pots was linked to elevated plasma levels of norepinephrine. |
2007-09-12 |
2023-08-12 |
human |