| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaohu Xie, Limin Xu, Huifen Liu, Weisheng Chen, Dingding Zhuang, Jianbing Zhang, Shiwei Duan, Wenhua Zho. Positive association between--1021TT genotype of dopamine beta hydroxylase gene and progressive behavior of injection heroin users. Neuroscience letters. vol 541. 2013-09-03. PMID:23510745. |
by balancing the ratios of dopamine and norepinephrine, dopamine beta hydroxylase (dbh) plays an important role in brain reward circuit that is involved with behavioral effects of heroin addiction. |
2013-09-03 |
2023-08-12 |
Not clear |
| Benjamin A Pawlisch, Cynthia A Kelm-Nelson, Sharon A Stevenson, Lauren V Riter. Behavioral indices of breeding readiness in female European starlings correlate with immunolabeling for catecholamine markers in brain areas involved in sexual motivation. General and comparative endocrinology. vol 179. issue 3. 2013-06-07. PMID:22999823. |
labeling for dopamine-beta-hydroxylase (dbh; the enzyme involved in norepinephrine synthesis) in the ventromedial nucleus of the hypothalamus (vmh) was densest in females that acquired nest sites compared to spring-like females without nest sites or fall-like females. |
2013-06-07 |
2023-08-12 |
Not clear |
| Meriem Gaval-Cruz, Larry Cameron Liles, Paul Michael Iuvone, David Weinshenke. Chronic inhibition of dopamine β-hydroxylase facilitates behavioral responses to cocaine in mice. PloS one. vol 7. issue 11. 2013-05-22. PMID:23209785. |
disulfiram inhibits dopamine β-hydroxylase (dbh), the enzyme that converts dopamine (da) to norepinephrine (ne) in noradrenergic neurons. |
2013-05-22 |
2023-08-12 |
mouse |
| Anthony Donsante, Patricia Sullivan, David S Goldstein, Lauren R Brinster, Stephen G Kale. L-threo-dihydroxyphenylserine corrects neurochemical abnormalities in a Menkes disease mouse model. Annals of neurology. vol 73. issue 2. 2013-05-21. PMID:23224983. |
among its multiple cellular tasks, atp7a transfers copper to dopamine beta hydroxylase (dbh) within the lumen of the golgi network or secretory granules, catalyzing the conversion of dopamine to norepinephrine. |
2013-05-21 |
2023-08-12 |
mouse |
| Omer Ates, Feryal Cam Celikel, Serap Erdogan Taycan, Saime Sezer, Nevin Karaku. Association between 1603C>T polymorphism of DBH gene and bipolar disorder in a Turkish population. Gene. vol 519. issue 2. 2013-05-20. PMID:23384717. |
dopamine-β-hydroxylase (dbh) is the enzyme responsible for the conversion of dopamine (da) to norepinephrine (ne, noradrenaline) which is a key neurotransmitter in the central and peripheral nervous systems. |
2013-05-20 |
2023-08-12 |
Not clear |
| Md Khalilur Rahman, Farhana Rahman, Tania Rahman, Takeshi Kat. Dopamine-β-Hydroxylase (DBH), Its Cofactors and Other Biochemical Parameters in the Serum of Neurological Patients in Bangladesh. International journal of biomedical science : IJBS. vol 5. issue 4. 2013-05-16. PMID:23675164. |
dopamine-β-hydroxylase (dbh) is a neurotransmitter synthesizing enzyme which catalyzes the formation of norepinephrine from dopamine. |
2013-05-16 |
2023-08-12 |
Not clear |
| M Khalilur Rahman, M Iqbal Choudhary, M Rafiqul Islam, Rahman M Hafizu. Developmental Changes of Catecholamine-mediating Enzyme - Dopamine-β- Hydroxylase and Its Cofactors in Central and Peripheral Tissues and Serum of Long-Evans Rats. International journal of biomedical science : IJBS. vol 8. issue 3. 2013-05-16. PMID:23675273. |
dopoamine-β-hydroxylase (dbh) is a catecholamine-synthesizing enzyme which catalyzes the formation of norepinephrine from dopamine. |
2013-05-16 |
2023-08-12 |
rat |
| Kingsley Osuala, Candice N Baker, Ha-Long Nguyen, Celines Martinez, David Weinshenker, Steven N Eber. Physiological and genomic consequences of adrenergic deficiency during embryonic/fetal development in mice: impact on retinoic acid metabolism. Physiological genomics. vol 44. issue 19. 2013-02-04. PMID:22911456. |
to perform this study, we used a mouse model with targeted disruption of the dopamine β-hydroxylase (dbh) gene, whose product is responsible for enzymatic conversion of dopamine into norepinephrine. |
2013-02-04 |
2023-08-12 |
mouse |
| Raja Parasuraman, Ewart de Visser, Ming-Kuan Lin, Pamela M Greenwoo. Dopamine beta hydroxylase genotype identifies individuals less susceptible to bias in computer-assisted decision making. PloS one. vol 7. issue 6. 2013-01-04. PMID:22761865. |
the dopamine beta hydroxylase (dbh) gene is thought to regulate the differential availability of dopamine and norepinephrine in prefrontal cortex. |
2013-01-04 |
2023-08-12 |
human |
| Raja Parasuraman, Ewart de Visser, Ming-Kuan Lin, Pamela M Greenwoo. Dopamine beta hydroxylase genotype identifies individuals less susceptible to bias in computer-assisted decision making. PloS one. vol 7. issue 6. 2013-01-04. PMID:22761865. |
based on two single nucleotide polymorphism (snps) of the dbh gene, -1041 c/t (rs1611115) and 444 g/a (rs1108580), participants were divided into groups of low and high dbh enzyme activity, where low enzyme activity is associated with greater dopamine relative to norepinephrine levels in cortex. |
2013-01-04 |
2023-08-12 |
human |
| Zhi Zhou, Lingling Wang, Xiaowei Shi, Feng Yue, Mengqiang Wang, Huan Zhang, Linsheng Son. The expression of dopa decarboxylase and dopamine beta hydroxylase and their responding to bacterial challenge during the ontogenesis of scallop Chlamys farreri. Fish & shellfish immunology. vol 33. issue 1. 2012-10-05. PMID:22521420. |
dopa decarboxylase (ddc) and dopamine beta hydroxylase (dbh) is responsible for the synthesis of dopamine and norepinephrine, respectively. |
2012-10-05 |
2023-08-12 |
Not clear |
| Camila Guindalini, Ronaldo Laranjeira, David Collier, Guilherme Messas, Homero Vallada, Gerome Bree. Dopamine-beta hydroxylase polymorphism and cocaine addiction. Behavioral and brain functions : BBF. vol 4. 2012-10-02. PMID:18173840. |
dopamine-beta hydroxylase (dbh) catalyzes the conversion of dopamine to norepinephrine and could, therefore, have an influence on both cocaine action and the basal sensitivity of neurotransmitter systems to cocaine. |
2012-10-02 |
2023-08-12 |
Not clear |
| C C Chen, C L William. Interactions between epinephrine, ascending vagal fibers, and central noradrenergic systems in modulating memory for emotionally arousing events. Frontiers in behavioral neuroscience. vol 6. 2012-10-02. PMID:22754515. |
the final study used double immunohistochemistry labeling of c-fos and dopamine beta hydroxylase (dbh), the enzyme for norepinephrine synthesis to determine if epinephrine administration alone or stimulation of the vagus nerve at an intensity identical to that which improved memory in experiment 1 produces similar patterns of neuronal activity in brain areas involved in processing memory for emotional events. |
2012-10-02 |
2023-08-12 |
Not clear |
| Y Fan, J Huang, M Duffourc, R L Kao, G A Ordway, R Huang, M-Y Zh. Transcription factor Phox2 upregulates expression of norepinephrine transporter and dopamine β-hydroxylase in adult rat brains. Neuroscience. vol 192. 2012-01-18. PMID:21763404. |
in the present study, recombinant lentiviral egfp-phox2a and -phox2b (vphox2a and vphox2b) were constructed to study the effects of phox2a/2b over-expression on dopamine β-hydroxylase (dbh) and norepinephrine transporter (net) levels in central noradrenergic neurons. |
2012-01-18 |
2023-08-12 |
rat |
| Junlin Zhang, Ryan D Darling, Ian A Paul, Kimberly L Simpson, Kevin Chen, Jean C Shih, Rick C S Li. Altered expression of tyrosine hydroxylase in the locus coeruleus noradrenergic system in citalopram neonatally exposed rats and monoamine oxidase a knock out mice. Anatomical record (Hoboken, N.J. : 2007). vol 294. issue 10. 2012-01-17. PMID:21901841. |
in this study, we performed double and/or triple immunofluorescent staining using antibodies against th, dbh, and/or norepinephrine transporter (net) to investigate the altered ne th expression of cortical fibers in citalopram (ctm)-exposed rats and monoamine oxidase (mao) a knock out (ko) mice. |
2012-01-17 |
2023-08-12 |
mouse |
| Chun-Hyung Kim, Amanda Leung, Yang Hoon Huh, Eungi Yang, Deog-Joong Kim, Pierre Leblanc, Hoon Ryu, Kyungjin Kim, Dong-Wook Kim, Emily M Garland, Satish R Raj, Italo Biaggioni, David Robertson, Kwang-Soo Ki. Norepinephrine deficiency is caused by combined abnormal mRNA processing and defective protein trafficking of dopamine beta-hydroxylase. The Journal of biological chemistry. vol 286. issue 11. 2011-05-16. PMID:21209083. |
human norepinephrine (ne) deficiency (or dopamine β-hydroxylase (dbh) deficiency) is a rare congenital disorder of primary autonomic failure, in which neurotransmitters ne and epinephrine are undetectable. |
2011-05-16 |
2023-08-12 |
human |
| Jason P Schroeder, Debra A Cooper, Jesse R Schank, Megan A Lyle, Meriem Gaval-Cruz, Yvonne E Ogbonmwan, Nikita Pozdeyev, Kimberly G Freeman, P Michael Iuvone, Gaylen L Edwards, Philip V Holmes, David Weinshenke. Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 12. 2011-02-16. PMID:20736996. |
we hypothesized that disulfiram's inhibition of dopamine β-hydroxylase (dbh), the catecholamine biosynthetic enzyme that converts dopamine (da) to norepinephrine (ne) in noradrenergic neurons, underlies the drug's ability to treat cocaine dependence. |
2011-02-16 |
2023-08-12 |
rat |
| Yuqing Chen, Kuixing Zhang, Gen Wen, Fangwen Rao, Amber P Sanchez, Lei Wang, Juan L Rodriguez-Flores, Manjula Mahata, Sushil K Mahata, Jill Waalen, Michael G Ziegler, Bruce A Hamilton, Daniel T O'Conno. Human dopamine β-hydroxylase promoter variant alters transcription in chromaffin cells, enzyme secretion, and blood pressure. American journal of hypertension. vol 24. issue 1. 2011-02-11. PMID:20814407. |
dopamine β-hydroxylase (dbh) plays an indispensable role in catecholamine synthesis by converting dopamine into norepinephrine. |
2011-02-11 |
2023-08-12 |
human |
| Kasia Radwanska, Evgenij Nikolaev, Leszek Kaczmare. Central noradrenergic lesion induced by DSP-4 impairs the acquisition of avoidance reactions and prevents molecular changes in the amygdala. Neurobiology of learning and memory. vol 94. issue 3. 2011-01-27. PMID:20650329. |
we found that dsp-4 treatment depleted the expression of the norepinephrine marker dopamine -hydroxylase (dbh) in the locus coeruleus and its projection area, the basolateral nucleus of the amygdala, confirming locus coeruleus noradrenergic lesion in the experimental animals. |
2011-01-27 |
2023-08-12 |
rat |
| Liming Fan, Courtney E Smith, Kathleen S Curti. Regional differences in estradiol effects on numbers of HSD2-containing neurons in the nucleus of the solitary tract of rats. Brain research. vol 1358. 2011-01-18. PMID:20728435. |
a small number of hsd2 immunoreactive neurons was also labeled for dopamine-β-hydroxylase (dbh), an enzyme involved in norepinephrine biosynthesis. |
2011-01-18 |
2023-08-12 |
rat |