| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Hui, Mei Han, Xu Feng Huang, Min Jie Ye, Ke Zheng, Jin Cai He, Meng Han Lv, Bao Hua Zhang, Jair C Soares, Xiang Yang Zhan. Possible association between DBH 19 bp insertion/deletion polymorphism and clinical symptoms in schizophrenia with tardive dyskinesia. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 6. 2016-02-22. PMID:25336319. |
moreover, dbh, whose activity and levels are strongly controlled by the dbh gene, is a key enzyme in the conversion of dopamine (da) to norepinephrine (ne) associated with excited behavior. |
2016-02-22 |
2023-08-13 |
Not clear |
| Alexander A Nevue, Cameron J Elde, David J Perkel, Christine V Portfor. Dopaminergic Input to the Inferior Colliculus in Mice. Frontiers in neuroanatomy. vol 9. 2016-02-02. PMID:26834578. |
we also immunostained for dopamine beta-hydroxylase (dbh), an enzyme critical for the conversion of dopamine to norepinephrine, to differentiate between dopaminergic and noradrenergic inputs. |
2016-02-02 |
2023-08-13 |
mouse |
| Maja Mustapic, Adam X Maihofer, Manjula Mahata, Yuqing Chen, Dewleen G Baker, Daniel T O'Connor, Caroline M Nievergel. The catecholamine biosynthetic enzyme dopamine β-hydroxylase (DBH): first genome-wide search positions trait-determining variants acting additively in the proximal promoter. Human molecular genetics. vol 23. issue 23. 2015-10-29. PMID:24986918. |
dopamine beta-hydroxylase (dbh) is the biosynthetic enzyme catalyzing formation of norepinephrine. |
2015-10-29 |
2023-08-13 |
human |
| Yi Zhou, Jun Wang, Yong He, Juan Zhou, Qian Xi, Xingbo Song, YuanXin Ye, Binwu Yin. Association between dopamine beta-hydroxylase 19-bp insertion/deletion polymorphism and major depressive disorder. Journal of molecular neuroscience : MN. vol 55. issue 2. 2015-09-11. PMID:24888991. |
dopamine beta-hydroxylase (dbh) catalyzes the conversion of dopamine to norepinephrine in central neurons and thus is critically involved in maintaining the transformational homeostasis. |
2015-09-11 |
2023-08-13 |
human |
| Pingyuan Gong, Jinting Liu, She Li, Xiaolin Zho. Dopamine beta-hydroxylase gene modulates individuals' empathic ability. Social cognitive and affective neuroscience. vol 9. issue 9. 2015-05-14. PMID:23988761. |
dopamine beta-hydroxylase (dbh), an enzyme that converts dopamine to norepinephrine, has broad influences on social functions. |
2015-05-14 |
2023-08-12 |
Not clear |
| Lorise C Gahring, Elizabeth Myers, Sierra Palumbos, Scott W Roger. Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PloS one. vol 9. issue 8. 2015-04-24. PMID:25093893. |
these chromaffin cells co-express α7(g), th and dbh, but they lack phenylethanolamine n-methyltransferase (pnmt) consistent with only norepinephrine (ne) synthesis. |
2015-04-24 |
2023-08-13 |
mouse |
| Pamela M Greenwood, Ming-Kuan Lin, Ramya Sundararajan, Karl J Fryxell, Raja Parasurama. Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine. Psychology and aging. vol 29. issue 2. 2015-03-18. PMID:24956005. |
since these genes encode enzymes influencing levels of extracellular dopamine, important for wm, we reasoned that individuals with low activity alleles of each snp (less efficient degradation of dopamine by comt and less efficient conversion of dopamine to norepinephrine by dbh) would have higher levels of extracellular dopamine and therefore better wm performance. |
2015-03-18 |
2023-08-13 |
Not clear |
| Elizabeth S Barrie, David Weinshenker, Anurag Verma, Sarah A Pendergrass, Leslie A Lange, Marylyn D Ritchie, James G Wilson, Helena Kuivaniemi, Gerard Tromp, David J Carey, Glenn S Gerhard, Murray H Brilliant, Scott J Hebbring, Joseph F Cubells, Julia K Pinsonneault, Greg J Norman, Wolfgang Sade. Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity. Circulation research. vol 115. issue 12. 2015-02-12. PMID:25326128. |
dopamine β-hydroxylase (dbh) catalyzes the conversion of dopamine to norepinephrine in the central nervous system and peripherally. |
2015-02-12 |
2023-08-13 |
human |
| Xiu-Fang Ding, Xiao-Hua Zhao, Yang Tao, Wei-Chao Zhong, Qin Fan, Jian-Xin Diao, Yuan-Liang Liu, Yu-Yao Chen, Jia-Xu Chen, Zhi-Ping L. Xiao Yao San Improves Depressive-Like Behaviors in Rats with Chronic Immobilization Stress through Modulation of Locus Coeruleus-Norepinephrine System. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-22. PMID:25610478. |
the serum norepinephrine (ne) concentrations and ne biosynthesis such as tyrosine hydroxylase (th), dopamine-β-hydroxylase (dbh), and corticotrophin-releasing-factor (crf) in lc were determined. |
2015-01-22 |
2023-08-13 |
rat |
| Yan Wang, Phillip R Musich, Moises A Serrano, Yue Zou, Jia Zhang, Meng-Yang Zh. Effects of DSP4 on the noradrenergic phenotypes and its potential molecular mechanisms in SH-SY5Y cells. Neurotoxicity research. vol 25. issue 2. 2014-09-07. PMID:23996700. |
dopamine β-hydroxylase (dbh) and norepinephrine (ne) transporter (net) are the noradrenergic phenotypes for their functional importance to noradrenergic neurons. |
2014-09-07 |
2023-08-12 |
Not clear |
| C M Ragan, J S Lonstei. Differential postpartum sensitivity to the anxiety-modulating effects of offspring contact is associated with innate anxiety and brainstem levels of dopamine beta-hydroxylase in female laboratory rats. Neuroscience. vol 256. 2014-08-27. PMID:24161285. |
levels of dopamine β-hydroxylase (dbh, norepinephrine synthesizing enzyme) and tryptophan hydroxylase-2 (tph2, serotonin synthesizing enzyme) were measured in the brainstem and dorsal raphe, respectively. |
2014-08-27 |
2023-08-12 |
rat |
| Debra A Cooper, Heather L Kimmel, Daniel F Manvich, Karl T Schmidt, David Weinshenker, Leonard L Howel. Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 350. issue 1. 2014-08-26. PMID:24817036. |
one of many biochemical actions of disulfiram is inhibition of dopamine β-hydroxylase (dbh), the enzyme that converts dopamine (da) to norepinephrine (ne) in noradrenergic neurons. |
2014-08-26 |
2023-08-13 |
rat |
| Lorenza S Colzato, Mischa de Rover, Wery P M van den Wildenberg, Sander Nieuwenhui. Genetic marker of norepinephrine synthesis predicts individual differences in post-error slowing: a pilot study. Neuropsychologia. vol 51. issue 13. 2014-06-25. PMID:23962674. |
in a sample of 100 healthy adults, we studied the dependency of an individual's size of pes on the dbh5'-ins/del polymorphism-a variation in the dbh gene associated with the production of the enzyme dopamine β-hydroxylase, which catalyzes the conversion of dopamine to norepinephrine. |
2014-06-25 |
2023-08-12 |
Not clear |
| M Khalilur Rahman, M Iqbal Choudhary, M Arif, M Monzur Morshe. Dopamine-β-Hydroxylase Activity and Levels of Its Cofactors and Other Biochemical Parameters in the Serum of Arsenicosis Patients of Bangladesh. International journal of biomedical science : IJBS. vol 10. issue 1. 2014-04-08. PMID:24711750. |
dopamine-β-hydroxylase (dbh) is a neurotransmitter (catecholamine)-mediating enzyme, which catalyzes the formation of norepinephrine from dopamine. |
2014-04-08 |
2023-08-13 |
Not clear |
| M Khalilur Rahman, M Iqbal Choudhary, M Arif, M Monzur Morshe. Dopamine-β-Hydroxylase Activity and Levels of Its Cofactors and Other Biochemical Parameters in the Serum of Arsenicosis Patients of Bangladesh. International journal of biomedical science : IJBS. vol 10. issue 1. 2014-04-08. PMID:24711750. |
the pathophysiological significance of the results could be correlated with the decreased in proteins and that in dbh activities as dbh deficiency is characterized by lack of sympathetic noradrenergic function.the general physiologic findings of autonomic function indicate that complete dbh deficiency include minimal or absent plasma norepinephrine and epinephrine. |
2014-04-08 |
2023-08-13 |
Not clear |
| Yan Fan, Ping Chen, Ying Li, Kui Cui, Daniel M Noel, Elizabeth D Cummins, Daniel J Peterson, Russell W Brown, Meng-Yang Zh. Corticosterone administration up-regulated expression of norepinephrine transporter and dopamine β-hydroxylase in rat locus coeruleus and its terminal regions. Journal of neurochemistry. vol 128. issue 3. 2014-03-12. PMID:24111919. |
in situ hybridization measurements showed that cort ingestion significantly increased mrna levels of norepinephrine transporter (net) and dopamine β-hydroxylase (dbh) in the lc region. |
2014-03-12 |
2023-08-12 |
rat |
| Sasuk Kim, Ji-Min Park, Jisook Moon, Hyun Jin Cho. Alpha-synuclein interferes with cAMP/PKA-dependent upregulation of dopamine β-hydroxylase and is associated with abnormal adaptive responses to immobilization stress. Experimental neurology. vol 252. 2014-03-10. PMID:24252179. |
based on our previous study showing that overexpression of wild-type or mutant α-synuclein (α-syn) interferes with camp/pka-dependent transcriptional activation in norepinephrine (ne)-producing cells, the effect of wild-type and mutant α-syn on camp response element (cre)-mediated regulation of the ne-synthesizing enzyme dopamine β-hydroxylase (dbh) was evaluated in this study. |
2014-03-10 |
2023-08-12 |
mouse |
| Daniel F Manvich, Lauren M DePoy, David Weinshenke. Dopamine β-hydroxylase inhibitors enhance the discriminative stimulus effects of cocaine in rats. The Journal of pharmacology and experimental therapeutics. vol 347. issue 3. 2014-01-23. PMID:24068832. |
inhibitors of dopamine β-hydroxylase (dbh), the enzyme that converts dopamine (da) to norepinephrine (ne) in noradrenergic cells, have shown promise for the treatment of cocaine abuse disorders. |
2014-01-23 |
2023-08-12 |
human |
| Li Hui, Xuan Zhang, Ya Qin Yu, Mei Han, Xu Feng Huang, Da Chun Chen, Zhi Ren Wang, Wei Li Du, Chang Gui Kou, Qiong Yu, Thomas R Kosten, Xiang Yang Zhan. Association between DBH 19 bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients. Schizophrenia research. vol 147. issue 2-3. 2014-01-17. PMID:23707643. |
many genes associated with dopamine (da) and norepinephrine (ne) systems influence cognitive deficits of schizophrenia patients, but one key enzyme is dopamine beta-hydroxylase (dbh), which converts da to ne and whose activity and levels are under strong genetic control. |
2014-01-17 |
2023-08-12 |
Not clear |
| Na Zhou, Qiong Yu, Xiaokun Li, Yaqin Yu, Changgui Kou, Wenjun Li, Hongqin Xu, Xingguang Luo, Lingjun Zuo, Thomas R Kosten, Xiang Yang Zhan. Association of the dopamine β-hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia. Human psychopharmacology. vol 28. issue 3. 2013-12-18. PMID:23559427. |
dopamine beta-hydroxylase (dbh) is a key enzyme in the conversion of dopamine to norepinephrine, and plasma dbh activity is altered in td patients. |
2013-12-18 |
2023-08-12 |
Not clear |