| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yumiko Nakamura, Hideaki Kaneto, Takeshi Miyatsuka, Taka-aki Matsuoka, Munehide Matsuhisa, Koichi Node, Masatsugu Hori, Yoshimitsu Yamasak. Marked increase of insulin gene transcription by suppression of the Rho/Rho-kinase pathway. Biochemical and biophysical research communications. vol 350. issue 1. 2006-11-28. PMID:16996478. |
northern blot analysis showed that insulin mrna levels were markedly increased by rho-kinase inhibitors, y-27632 and fasudil, in beta-cell-derived hit-t15 cells. |
2006-11-28 |
2023-08-12 |
mouse |
| Marzena Grden, Marzena Podgorska, Katarzyna Kocbuch, Andrzej Szutowicz, Tadeusz Pawelczy. Expression of adenosine receptors in cardiac fibroblasts as a function of insulin and glucose level. Archives of biochemistry and biophysics. vol 455. issue 1. 2006-11-22. PMID:17011509. |
the goal of present work was to examine the effects of glucose and insulin on adenosine receptors (ars) mrna and protein level in primary culture of rat cfs by means of real-time pcr and western blot. |
2006-11-22 |
2023-08-12 |
rat |
| Git S Johansson, Hans J Arnqvis. Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells. American journal of physiology. Endocrinology and metabolism. vol 291. issue 5. 2006-11-21. PMID:16803852. |
vsmcs from rat thoracic aorta were serum starved, stimulated with igf-i or insulin, lysed, immunoprecipitated, and analyzed by western blot. |
2006-11-21 |
2023-08-12 |
rat |
| Sonia Fernández-Veledo, Rosario Hernandez, Teresa Teruel, Jose Antonio Mas, Manuel Ros, Margarita Lorenz. Ceramide mediates TNF-alpha-induced insulin resistance on GLUT4 gene expression in brown adipocytes. Archives of physiology and biochemistry. vol 112. issue 1. 2006-09-12. PMID:16754199. |
tumour necrosis factor (tnf)-alpha impaired insulin induction on glut4 mrna in foetal brown adipocytes, as demonstrated by quantitative rt-pcr and northern blot. |
2006-09-12 |
2023-08-12 |
cat |
| Kamlesh V Vavaiya, Sachin A Paranjape, Gopal D Patil, Karen P Brisk. Vagal complex monocarboxylate transporter-2 expression during hypoglycemia. Neuroreport. vol 17. issue 10. 2006-09-08. PMID:16791096. |
western blot analyses showed that male and estrogen-treated ovariectomized female rats exhibit opposite changes in monocarboxylate transporter-2 levels after one insulin injection, as well as divergent patterns of adaptation to this metabolic challenge. |
2006-09-08 |
2023-08-12 |
rat |
| M Chiara Cantarini, Suzanne M de la Monte, Maoyin Pang, Ming Tong, Antonia D'Errico, Franco Trevisani, Jack R Wand. Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms. Hepatology (Baltimore, Md.). vol 44. issue 2. 2006-08-24. PMID:16871543. |
the mrna transcript levels of aah, insulin receptor substrate (irs), insulin and insulin-like growth factor (igf) receptors and polypeptides, notch, jagged, and hes were measured in 15 paired samples of hcc and adjacent hcc-free human liver biopsy specimens using real-time quantitative rt-pcr and western blot analysis. |
2006-08-24 |
2023-08-12 |
human |
| Cindy X Fang, Thomas A Doser, Xiaoping Yang, Nair Sreejayan, Jun Re. Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt. Aging cell. vol 5. issue 2. 2006-05-31. PMID:16626396. |
western blot analysis revealed reduced akt expression and insulin (5 mu g(-1))-stimulated akt phosphorylation, elevated ptp1b expression and diminished basal insulin receptor tyrosine phosphorylation associated with comparable insulin receptor expression in aged fvb mouse hearts. |
2006-05-31 |
2023-08-12 |
mouse |
| S Schäfer-Somi, K R Herkner, S Neubauer, M Egerbacher, M Patzl, S Pollak, O Ali Aksoy, H B Beceriklisoy, H Kanca, M Findik, H Kalender, S Asla. A screening for the occurrence of autoreactive antibodies in sera of pregnant and non-pregnant bitches. Reproduction in domestic animals = Zuchthygiene. vol 41. issue 1. 2006-05-18. PMID:16420328. |
in addition, sera were screened for thyroid specific aab, namely thyroglobulin, thyroid peroxidase (tpo), t3 and t4, and for aab against insulin by elisa or western blot (tpo). |
2006-05-18 |
2023-08-12 |
human |
| Gipsy Majumdar, Adrienne Harrington, James Hungerford, Antonio Martinez-Hernandez, Ivan C Gerling, Rajendra Raghow, Solomon Solomo. Insulin dynamically regulates calmodulin gene expression by sequential o-glycosylation and phosphorylation of sp1 and its subcellular compartmentalization in liver cells. The Journal of biological chemistry. vol 281. issue 6. 2006-04-11. PMID:16332679. |
analyses of the total, o-glcnac-modified, or phosphorylated sp1 by western blot and mass spectrometry corroborated the sequential and reciprocal control of post-translational modifications of sp1 in response to insulin. |
2006-04-11 |
2023-08-12 |
Not clear |
| Daniel Andrade Cunha, Everardo M Carneiro, Mônica de C Alves, Angélica Gobbi Jorge, Sylvia Morais de Sousa, Antonio C Boschero, Mário J A Saad, Lício A Velloso, Eduardo M Roch. Insulin secretion by rat lacrimal glands: effects of systemic and local variables. American journal of physiology. Endocrinology and metabolism. vol 289. issue 5. 2005-12-09. PMID:15985452. |
insulin was located in the apical areas of acinar cells by immunoperoxidase and the expression of glut-1, but not pdx-1, was confirmed by western blot. |
2005-12-09 |
2023-08-12 |
rat |
| Michela Zanetti, Rocco Barazzoni, Marco Stebel, Elena Roder, Gianni Biolo, Francisco E Baralle, Luigi Cattin, Gianfranco Guarnier. Dysregulation of the endothelial nitric oxide synthase-soluble guanylate cyclase pathway is normalized by insulin in the aorta of diabetic rat. Atherosclerosis. vol 181. issue 1. 2005-10-27. PMID:15939056. |
expression and function of enos, sgc and protein kinase g (pkg) were studied by western blot analysis and vasorelaxation to no-donor in thoracic aortas from control (con) and streptozotocin (szt)-induced diabetic rats during uncontrolled diabetes (dm) and insulin treatment (ins) for 8 weeks. |
2005-10-27 |
2023-08-12 |
rat |
| Eugenio D'Amico, Hongxiang Hui, Nasif Khoury, Umberto Di Mario, Riccardo Perfett. Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugs. Journal of molecular endocrinology. vol 34. issue 2. 2005-09-22. PMID:15821104. |
the secretion of insulin and the expression of apoptosis-related proteins were investigated by ria and western blot analysis. |
2005-09-22 |
2023-08-12 |
mouse |
| Masatsune Suzuki, Hirotoshi Kakuta, Akimitsu Takahashi, Hitoshi Shimano, Kaoruko Tada-Iida, Tomotaka Yokoo, Rumi Kihara, Nobuhiro Yamad. Effects of atorvastatin on glucose metabolism and insulin resistance in KK/Ay mice. Journal of atherosclerosis and thrombosis. vol 12. issue 2. 2005-09-13. PMID:15942117. |
northern blot analysis revealed decreases in levels of mrna of sterol regulatory element binding protein-1 (srebp-1) and glucose-6-phosphatase (g6pase), and it may play a role in the improvement of glucose metabolism and insulin resistance. |
2005-09-13 |
2023-08-12 |
mouse |
| Tanja Jevdjovic, Caroline Maake, Cornelia Zwimpfer, Gunthild Krey, Elisabeth Eppler, Jürgen Zapf, Manfred Reineck. The effect of hypophysectomy on pancreatic islet hormone and insulin-like growth factor I content and mRNA expression in rat. Histochemistry and cell biology. vol 123. issue 2. 2005-09-12. PMID:15812646. |
northern blot analysis gave a 2.6-, 4.5-, and 2.2-fold increase in pancreatic insulin, glucagon, and somatostatin mrna levels, respectively, in hypox rats, and a 2.3-fold decrease in igf-i mrna levels. |
2005-09-12 |
2023-08-12 |
rat |
| Abdul Jaleel, Panagiotis Halvatsiotis, Brian Williamson, Peter Juhasz, Stephen Martin, K Sreekumaran Nai. Identification of Amadori-modified plasma proteins in type 2 diabetes and the effect of short-term intensive insulin treatment. Diabetes care. vol 28. issue 3. 2005-06-30. PMID:15735202. |
the objective of the current study was to utilize two-dimensional gel electrophoresis, western blot, and mass spectrometry to identify amadori-modified plasma proteins in type 2 diabetic patients with poor glycemic control and assess the impact of short-term insulin treatment on the glycation of these proteins. |
2005-06-30 |
2023-08-12 |
Not clear |
| Célia Lopes Da Costa, Marta Sampaio De Freitas, Anibal Sanchez Mour. Insulin secretion and GLUT-2 expression in undernourished neonate rats. The Journal of nutritional biochemistry. vol 15. issue 4. 2005-06-24. PMID:15068817. |
glucose-induced insulin secretion by pancreatic islets was analyzed by radioimmunoassay and glut-2 expression in beta-cells by western blot. |
2005-06-24 |
2023-08-12 |
rat |
| L Zhao, Z Li, M Kullin, L A H Borg, F A Karlsso. Alterations in net glucose uptake and in the pancreatic B-cell GLUT2 transporter induced by diazoxide and by secretory stimuli. The Journal of endocrinology. vol 185. issue 2. 2005-06-16. PMID:15845921. |
islet glut2 and insulin were determined by quantitative immunohistochemistry and glut2 was also determined by western blot analysis. |
2005-06-16 |
2023-08-12 |
rat |
| Anita M Hennige, Rainer Lehmann, Cora Weigert, Klaus Moeschel, Myriam Schäuble, Elisabeth Metzinger, Reiner Lammers, Hans-Ulrich Härin. Insulin glulisine: insulin receptor signaling characteristics in vivo. Diabetes. vol 54. issue 2. 2005-04-11. PMID:15677493. |
c57bl/6 mice were injected with insulin glulisine or regular insulin and western blot analysis was performed for liver and muscle tissue. |
2005-04-11 |
2023-08-12 |
mouse |
| Edward A Carter, Deborah Burks, Alan J Fischman, Morris White, Ronald G Tompkin. Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue. International journal of molecular medicine. vol 14. issue 4. 2005-03-28. PMID:15375597. |
at 3 weeks after injury, glucose production by the liver and utilization by skeletal muscle was measured under insulin clamp conditions, insulin receptor binding was measured in skeletal muscle, liver and adipose tissue membranes and irs-1 expression was measured by western blot methods. |
2005-03-28 |
2023-08-12 |
rat |
| Marianne S Anderson, M Thamotharan, Doris Kao, Sherin U Devaskar, Liping Qiao, Jacob E Friedman, William W Ha. Effects of acute hyperinsulinemia on insulin signal transduction and glucose transporters in ovine fetal skeletal muscle. American journal of physiology. Regulatory, integrative and comparative physiology. vol 288. issue 2. 2005-02-16. PMID:15539611. |
serial skeletal muscle biopsies were taken from each fetus during the clamp and assayed by western blot for selected insulin signal transduction proteins. |
2005-02-16 |
2023-08-12 |
Not clear |