| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Catarina Pinto Reis, António J Ribeiro, Simone Houng, Francisco Veiga, Ronald J Neufel. Nanoparticulate delivery system for insulin: design, characterization and in vitro/in vivo bioactivity. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 30. issue 5. 2007-05-31. PMID:17280820. |
insulin encapsulation efficiency and in vitro release were determined by bradford protein assay and bioactivity determined in vitro using a newly developed western blot immunoassay and in vivo using wistar diabetic rats. |
2007-05-31 |
2023-08-12 |
rat |
| HaiYan Liu, DongMei Zhang, Xiao Xu, XiaoDong Liu, GuangJi Wang, Lin Xie, XiaoYan Pang, Li Li. Attenuated function and expression of P-glycoprotein at blood-brain barrier and increased brain distribution of phenobarbital in streptozotocin-induced diabetic mice. European journal of pharmacology. vol 561. issue 1-3. 2007-05-22. PMID:17349620. |
the results showed that the brain-to-plasma concentration ratio value of rodamine123 in diabetic mice was significantly higher than that of non-diabetic mice, western blot suggested that the protein level of p-glycoprotein in the brain of 3-week diabetic mice was significantly lower than that of non-diabetic mice, and insulin treatment restored the impairment of p-glycoprotein. |
2007-05-22 |
2023-08-12 |
mouse |
| Sachin Paranjape, Kamlesh Vavaiya, Ajay Kale, Karen Brisk. Role of dorsal vagal motor nucleus orexin-receptor-1 in glycemic responses to acute versus repeated insulin administration. Neuropeptides. vol 41. issue 2. 2007-05-16. PMID:17276508. |
effects of acute versus repeated insulin administration on orx-a and or-1 protein levels in the microdissected dorsal vagal complex (dvc) were evaluated by radioimmunoassay and western blot analyses, respectively. |
2007-05-16 |
2023-08-12 |
rat |
| Olga Hrytsenko, James R Wright, Carol M Morrison, Bill Pohajda. Insulin expression in the brain and pituitary cells of tilapia (Oreochromis niloticus). Brain research. vol 1135. issue 1. 2007-04-05. PMID:17196948. |
furthermore, insulin mrna and immunoreactive insulin-like protein was detected in the pituitary gland using in situ hybridization, immunohistochemistry, and western blot analysis. |
2007-04-05 |
2023-08-12 |
Not clear |
| Tayaramma Thatava, Thatava Tayaramma, Bin Ma, Manfred Rohde, Hubert Maye. Chromatin-remodeling factors allow differentiation of bone marrow cells into insulin-producing cells. Stem cells (Dayton, Ohio). vol 24. issue 12. 2007-02-08. PMID:16990588. |
western blot analysis demonstrated the presence of stored insulin. |
2007-02-08 |
2023-08-12 |
Not clear |
| Esther Velázquez, Antonio Santos, Agustin Montes, Enrique Blázquez, Juan Miguel Ruiz-Albusa. 25-Hydroxycholesterol has a dual effect on the proliferation of cultured rat astrocytes. Neuropharmacology. vol 51. issue 2. 2006-12-04. PMID:16678217. |
finally, in media with albumin alone or in the presence of fetal bovine serum, growth factors, insulin or forskolin, 25-oh-cholesterol did not affect the expression of either c-fos mrna or c-fos protein, as measured by real-time quantitative pcr or by western blot, respectively. |
2006-12-04 |
2023-08-12 |
rat |
| Yumiko Nakamura, Hideaki Kaneto, Takeshi Miyatsuka, Taka-aki Matsuoka, Munehide Matsuhisa, Koichi Node, Masatsugu Hori, Yoshimitsu Yamasak. Marked increase of insulin gene transcription by suppression of the Rho/Rho-kinase pathway. Biochemical and biophysical research communications. vol 350. issue 1. 2006-11-28. PMID:16996478. |
northern blot analysis showed that insulin mrna levels were markedly increased by rho-kinase inhibitors, y-27632 and fasudil, in beta-cell-derived hit-t15 cells. |
2006-11-28 |
2023-08-12 |
mouse |
| Marzena Grden, Marzena Podgorska, Katarzyna Kocbuch, Andrzej Szutowicz, Tadeusz Pawelczy. Expression of adenosine receptors in cardiac fibroblasts as a function of insulin and glucose level. Archives of biochemistry and biophysics. vol 455. issue 1. 2006-11-22. PMID:17011509. |
the goal of present work was to examine the effects of glucose and insulin on adenosine receptors (ars) mrna and protein level in primary culture of rat cfs by means of real-time pcr and western blot. |
2006-11-22 |
2023-08-12 |
rat |
| Git S Johansson, Hans J Arnqvis. Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells. American journal of physiology. Endocrinology and metabolism. vol 291. issue 5. 2006-11-21. PMID:16803852. |
vsmcs from rat thoracic aorta were serum starved, stimulated with igf-i or insulin, lysed, immunoprecipitated, and analyzed by western blot. |
2006-11-21 |
2023-08-12 |
rat |
| Sonia Fernández-Veledo, Rosario Hernandez, Teresa Teruel, Jose Antonio Mas, Manuel Ros, Margarita Lorenz. Ceramide mediates TNF-alpha-induced insulin resistance on GLUT4 gene expression in brown adipocytes. Archives of physiology and biochemistry. vol 112. issue 1. 2006-09-12. PMID:16754199. |
tumour necrosis factor (tnf)-alpha impaired insulin induction on glut4 mrna in foetal brown adipocytes, as demonstrated by quantitative rt-pcr and northern blot. |
2006-09-12 |
2023-08-12 |
cat |
| Kamlesh V Vavaiya, Sachin A Paranjape, Gopal D Patil, Karen P Brisk. Vagal complex monocarboxylate transporter-2 expression during hypoglycemia. Neuroreport. vol 17. issue 10. 2006-09-08. PMID:16791096. |
western blot analyses showed that male and estrogen-treated ovariectomized female rats exhibit opposite changes in monocarboxylate transporter-2 levels after one insulin injection, as well as divergent patterns of adaptation to this metabolic challenge. |
2006-09-08 |
2023-08-12 |
rat |
| M Chiara Cantarini, Suzanne M de la Monte, Maoyin Pang, Ming Tong, Antonia D'Errico, Franco Trevisani, Jack R Wand. Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms. Hepatology (Baltimore, Md.). vol 44. issue 2. 2006-08-24. PMID:16871543. |
the mrna transcript levels of aah, insulin receptor substrate (irs), insulin and insulin-like growth factor (igf) receptors and polypeptides, notch, jagged, and hes were measured in 15 paired samples of hcc and adjacent hcc-free human liver biopsy specimens using real-time quantitative rt-pcr and western blot analysis. |
2006-08-24 |
2023-08-12 |
human |
| Cindy X Fang, Thomas A Doser, Xiaoping Yang, Nair Sreejayan, Jun Re. Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt. Aging cell. vol 5. issue 2. 2006-05-31. PMID:16626396. |
western blot analysis revealed reduced akt expression and insulin (5 mu g(-1))-stimulated akt phosphorylation, elevated ptp1b expression and diminished basal insulin receptor tyrosine phosphorylation associated with comparable insulin receptor expression in aged fvb mouse hearts. |
2006-05-31 |
2023-08-12 |
mouse |
| S Schäfer-Somi, K R Herkner, S Neubauer, M Egerbacher, M Patzl, S Pollak, O Ali Aksoy, H B Beceriklisoy, H Kanca, M Findik, H Kalender, S Asla. A screening for the occurrence of autoreactive antibodies in sera of pregnant and non-pregnant bitches. Reproduction in domestic animals = Zuchthygiene. vol 41. issue 1. 2006-05-18. PMID:16420328. |
in addition, sera were screened for thyroid specific aab, namely thyroglobulin, thyroid peroxidase (tpo), t3 and t4, and for aab against insulin by elisa or western blot (tpo). |
2006-05-18 |
2023-08-12 |
human |
| Gipsy Majumdar, Adrienne Harrington, James Hungerford, Antonio Martinez-Hernandez, Ivan C Gerling, Rajendra Raghow, Solomon Solomo. Insulin dynamically regulates calmodulin gene expression by sequential o-glycosylation and phosphorylation of sp1 and its subcellular compartmentalization in liver cells. The Journal of biological chemistry. vol 281. issue 6. 2006-04-11. PMID:16332679. |
analyses of the total, o-glcnac-modified, or phosphorylated sp1 by western blot and mass spectrometry corroborated the sequential and reciprocal control of post-translational modifications of sp1 in response to insulin. |
2006-04-11 |
2023-08-12 |
Not clear |
| Daniel Andrade Cunha, Everardo M Carneiro, Mônica de C Alves, Angélica Gobbi Jorge, Sylvia Morais de Sousa, Antonio C Boschero, Mário J A Saad, Lício A Velloso, Eduardo M Roch. Insulin secretion by rat lacrimal glands: effects of systemic and local variables. American journal of physiology. Endocrinology and metabolism. vol 289. issue 5. 2005-12-09. PMID:15985452. |
insulin was located in the apical areas of acinar cells by immunoperoxidase and the expression of glut-1, but not pdx-1, was confirmed by western blot. |
2005-12-09 |
2023-08-12 |
rat |
| Michela Zanetti, Rocco Barazzoni, Marco Stebel, Elena Roder, Gianni Biolo, Francisco E Baralle, Luigi Cattin, Gianfranco Guarnier. Dysregulation of the endothelial nitric oxide synthase-soluble guanylate cyclase pathway is normalized by insulin in the aorta of diabetic rat. Atherosclerosis. vol 181. issue 1. 2005-10-27. PMID:15939056. |
expression and function of enos, sgc and protein kinase g (pkg) were studied by western blot analysis and vasorelaxation to no-donor in thoracic aortas from control (con) and streptozotocin (szt)-induced diabetic rats during uncontrolled diabetes (dm) and insulin treatment (ins) for 8 weeks. |
2005-10-27 |
2023-08-12 |
rat |
| Eugenio D'Amico, Hongxiang Hui, Nasif Khoury, Umberto Di Mario, Riccardo Perfett. Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugs. Journal of molecular endocrinology. vol 34. issue 2. 2005-09-22. PMID:15821104. |
the secretion of insulin and the expression of apoptosis-related proteins were investigated by ria and western blot analysis. |
2005-09-22 |
2023-08-12 |
mouse |
| Masatsune Suzuki, Hirotoshi Kakuta, Akimitsu Takahashi, Hitoshi Shimano, Kaoruko Tada-Iida, Tomotaka Yokoo, Rumi Kihara, Nobuhiro Yamad. Effects of atorvastatin on glucose metabolism and insulin resistance in KK/Ay mice. Journal of atherosclerosis and thrombosis. vol 12. issue 2. 2005-09-13. PMID:15942117. |
northern blot analysis revealed decreases in levels of mrna of sterol regulatory element binding protein-1 (srebp-1) and glucose-6-phosphatase (g6pase), and it may play a role in the improvement of glucose metabolism and insulin resistance. |
2005-09-13 |
2023-08-12 |
mouse |
| Tanja Jevdjovic, Caroline Maake, Cornelia Zwimpfer, Gunthild Krey, Elisabeth Eppler, Jürgen Zapf, Manfred Reineck. The effect of hypophysectomy on pancreatic islet hormone and insulin-like growth factor I content and mRNA expression in rat. Histochemistry and cell biology. vol 123. issue 2. 2005-09-12. PMID:15812646. |
northern blot analysis gave a 2.6-, 4.5-, and 2.2-fold increase in pancreatic insulin, glucagon, and somatostatin mrna levels, respectively, in hypox rats, and a 2.3-fold decrease in igf-i mrna levels. |
2005-09-12 |
2023-08-12 |
rat |