| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elisabetta Tronci, Francesco Napolitano, Ana Muñoz, Camino Fidalgo, Francesca Rossi, Anders Björklund, Alessandro Usiello, Manolo Cart. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats. Experimental neurology. vol 297. 2017-10-05. PMID:28757258. |
results showed that the aav-bdnf vector injection induced striatal over-expression of bdnf, as well as striatal and pallidal serotonin axon hyperinnervation. |
2017-10-05 |
2023-08-13 |
rat |
| Elisabetta Tronci, Francesco Napolitano, Ana Muñoz, Camino Fidalgo, Francesca Rossi, Anders Björklund, Alessandro Usiello, Manolo Cart. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats. Experimental neurology. vol 297. 2017-10-05. PMID:28757258. |
this study suggests that bdnf over-expression, by inducing changes in pre-synaptic serotonin axonal trophism, is able to exacerbate maladaptive responses to l-dopa administration. |
2017-10-05 |
2023-08-13 |
rat |
| Chihiro Ishikawa, Haiyan Li, Rin Ogura, Yuko Yoshimura, Takashi Kudo, Masaki Shirakawa, Dai Shiba, Satoru Takahashi, Hironobu Morita, Takashi Shig. Effects of gravity changes on gene expression of BDNF and serotonin receptors in the mouse brain. PloS one. vol 12. issue 6. 2017-09-14. PMID:28591153. |
effects of gravity changes on gene expression of bdnf and serotonin receptors in the mouse brain. |
2017-09-14 |
2023-08-13 |
mouse |
| Chihiro Ishikawa, Haiyan Li, Rin Ogura, Yuko Yoshimura, Takashi Kudo, Masaki Shirakawa, Dai Shiba, Satoru Takahashi, Hironobu Morita, Takashi Shig. Effects of gravity changes on gene expression of BDNF and serotonin receptors in the mouse brain. PloS one. vol 12. issue 6. 2017-09-14. PMID:28591153. |
here we investigated the effects of centrifugation-induced gravity changes on gene expression of brain-derived neurotrophic factor (bdnf) and serotonin receptors (5-htrs) in the mouse brain. |
2017-09-14 |
2023-08-13 |
mouse |
| Ting Li-Tempel, Mauro F Larra, Ulrike Winnikes, Tobias Tempel, Roel H DeRijk, André Schulz, Hartmut Schächinger, Jobst Meyer, Andrea B Schot. Polymorphisms of genes related to the hypothalamic-pituitary-adrenal axis influence the cortisol awakening response as well as self-perceived stress. Biological psychology. vol 119. 2017-09-13. PMID:27427534. |
we examined the influence of variants of four relevant candidate genes; the mineralocorticoid receptor gene (mr), the glucocorticoid receptor gene (gr), the serotonin transporter gene (5-htt) and the gene encoding the brain-derived neurotrophic factor (bdnf) on car and self-perceived stress in 217 healthy subjects. |
2017-09-13 |
2023-08-13 |
human |
| N N Kudryavtseva, D A Smagin, I L Kovalenko, A G Galyamina, G B Vishnivetskaya, V N Babenko, Yu L Orlo. [Serotonergic genes in the development of anxiety/depression-like state and pathology of aggressive behavior in male mice: RNA-seq data]. Molekuliarnaia biologiia. vol 51. issue 2. 2017-08-14. PMID:28537235. |
using the data of whole transcriptome analysis (rna-seq), the changes in the expression of serotonergic genes involved in the synthesis, inactivation, and reception of serotonin, as well as of the creb1 (transcription factor) gene and the bdnf (brain-derived neurotrophic factor) gene were detected in the striatum (str), ventral tegmental area (vta), midbrain raphe nuclei (mrn), hypothalamus (hyp), and hippocampus (hip) of defeated and aggressive male mice. |
2017-08-14 |
2023-08-13 |
mouse |
| N Sun, C-X Yang, Z-F Liu, X-R Li, Y Xu, K-R Zhan. Effects of polymorphisms of serotonin transporter promoter (5-HTTLPR) and brain derived neurotrophic factor gene (G196A rs6265) on the risk of major depressive disorder in the Chinese Han population. European review for medical and pharmacological sciences. vol 20. issue 9. 2017-07-24. PMID:27212180. |
previous studies have shown a significant interaction between serotonin and brain-derived neurotrophic factor (bdnf) in brain function. |
2017-07-24 |
2023-08-13 |
Not clear |
| N Sun, C-X Yang, Z-F Liu, X-R Li, Y Xu, K-R Zhan. Effects of polymorphisms of serotonin transporter promoter (5-HTTLPR) and brain derived neurotrophic factor gene (G196A rs6265) on the risk of major depressive disorder in the Chinese Han population. European review for medical and pharmacological sciences. vol 20. issue 9. 2017-07-24. PMID:27212180. |
the serotonin transporter protein promoter polymorphism (5-httlpr) and bdnf (rs6265) are two of the most studied candidate gene polymorphisms in relation to mdd. |
2017-07-24 |
2023-08-13 |
Not clear |
| Jian-Ping Zhang, Todd Lencz, Ryan X Zhang, Masahiro Nitta, Lawrence Maayan, Majnu John, Delbert G Robinson, W Wolfgang Fleischhacker, Rene S Kahn, Roel A Ophoff, John M Kane, Anil K Malhotra, Christoph U Correl. Pharmacogenetic Associations of Antipsychotic Drug-Related Weight Gain: A Systematic Review and Meta-analysis. Schizophrenia bulletin. vol 42. issue 6. 2017-07-24. PMID:27217270. |
combined, 13 snps from 9 genes (adrenoceptor alpha-2a [adra2a], adrenoceptor beta 3 [adrb3], brain-derived neurotrophic factor [bdnf], dopamine receptor d2 [drd2], guanine nucleotide binding protein [gnb3], 5-hydroxytryptamine (serotonin) receptor 2c [htr2c], insulin-induced gene 2 [insig2], melanocortin-4 receptor [mc4r], and synaptosomal-associated protein, 25kda [snap25]) were significantly associated with antipsychotic-related weight gain (p-values < .05-.001). |
2017-07-24 |
2023-08-13 |
Not clear |
| Terry McMorri. Developing the catecholamines hypothesis for the acute exercise-cognition interaction in humans: Lessons from animal studies. Physiology & behavior. vol 165. 2017-07-11. PMID:27526999. |
the catecholamines hypothesis for the acute exercise-cognition interaction in humans fails to adequately explain the interaction between peripherally circulating catecholamines and brain concentrations; how different exercise intensities×durations affect different cognitive tasks; and how brain catecholamines, glucocorticoids, bdnf and 5-hydroxytryptamine interact. |
2017-07-11 |
2023-08-13 |
Not clear |
| C D Pandya, N Hoda, A Crider, D Peter, A Kutiyanawalla, S Kumar, A O Ahmed, G Turecki, C M Hernandez, A V Terry, A Pilla. Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice. Molecular psychiatry. vol 22. issue 5. 2017-06-29. PMID:27620841. |
serotonin (5-hydroxytryptamine, 5-ht) and brain-derived neurotrophic factor (bdnf) are two signaling molecules that have important regulatory roles in the development and plasticity of neural circuits that are known to be altered in depression. |
2017-06-29 |
2023-08-13 |
mouse |
| C D Pandya, N Hoda, A Crider, D Peter, A Kutiyanawalla, S Kumar, A O Ahmed, G Turecki, C M Hernandez, A V Terry, A Pilla. Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice. Molecular psychiatry. vol 22. issue 5. 2017-06-29. PMID:27620841. |
however, the mechanism by which 5-ht regulates bdnf signaling is unknown. |
2017-06-29 |
2023-08-13 |
mouse |
| C D Pandya, N Hoda, A Crider, D Peter, A Kutiyanawalla, S Kumar, A O Ahmed, G Turecki, C M Hernandez, A V Terry, A Pilla. Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice. Molecular psychiatry. vol 22. issue 5. 2017-06-29. PMID:27620841. |
in the present study, we found that 5-ht treatment increases bdnf receptor, trkb (tropomyosin related kinase b), levels in mouse primary cortical neurons via a rac1 (ras-related c3 botulinum toxin substrate 1)-dependent mechanism. |
2017-06-29 |
2023-08-13 |
mouse |
| Rocío Beatriz Foltran, Silvina Laura Dia. BDNF isoforms: a round trip ticket between neurogenesis and serotonin? Journal of neurochemistry. vol 138. issue 2. 2017-06-23. PMID:27167299. |
bdnf isoforms: a round trip ticket between neurogenesis and serotonin? |
2017-06-23 |
2023-08-13 |
Not clear |
| Rocío Beatriz Foltran, Silvina Laura Dia. BDNF isoforms: a round trip ticket between neurogenesis and serotonin? Journal of neurochemistry. vol 138. issue 2. 2017-06-23. PMID:27167299. |
interestingly, around this triumvirate of bdnf, serotonin, and neurogenesis, a series of recent research has emerged with apparently counterintuitive results. |
2017-06-23 |
2023-08-13 |
Not clear |
| Maeson S Latsko, T Lee Gilman, Lindsey M Matt, K Maria Nylocks, Karin G Coifman, Aaron M Jasno. A Novel Interaction between Tryptophan Hydroxylase 2 (TPH2) Gene Polymorphism (rs4570625) and BDNF Val66Met Predicts a High-Risk Emotional Phenotype in Healthy Subjects. PloS one. vol 11. issue 10. 2017-06-14. PMID:27695066. |
recent studies in humans and mutant mouse models suggest biological epistasis between bdnf and genes involved in serotonin regulation. |
2017-06-14 |
2023-08-13 |
mouse |
| Paulina Jaworska-Andryszewska, Janusz Rybakowsk. Negative experiences in childhood and the development and course of bipolar disorder. Psychiatria polska. vol 50. issue 5. 2017-05-10. PMID:27992891. |
molecular genetic studies indicate the possibility of interactions between environmental factors (stress) and the polymorphisms of serotonin transporter, brain-derived neurotrophic factor (bdnf) and toll-like receptor (tlr2). |
2017-05-10 |
2023-08-13 |
Not clear |
| Mei-Rong Chen, Ping Dai, Shu-Fen Wang, Shu-Hua Song, Hang-Ping Wang, Ya Zhao, Ting-Hua Wang, Jia Li. BDNF Overexpression Exhibited Bilateral Effect on Neural Behavior in SCT Mice Associated with AKT Signal Pathway. Neurochemical research. vol 41. issue 10. 2017-04-04. PMID:27278760. |
immunohistochemistry was employed to detect the location and the expression of bdnf, neun, 5-ht, gap-43, gfap as well as cgrp, and the level of p-akt and akt were examined through western blot analysis. |
2017-04-04 |
2023-08-13 |
mouse |
| Mei-Rong Chen, Ping Dai, Shu-Fen Wang, Shu-Hua Song, Hang-Ping Wang, Ya Zhao, Ting-Hua Wang, Jia Li. BDNF Overexpression Exhibited Bilateral Effect on Neural Behavior in SCT Mice Associated with AKT Signal Pathway. Neurochemical research. vol 41. issue 10. 2017-04-04. PMID:27278760. |
meanwhile, the neun, 5-ht and gap-43 positive cells were markedly increased in ventral horn in bdnf overexpression animals, compared with wt mice with sct. |
2017-04-04 |
2023-08-13 |
mouse |
| Jungyun Kim, Heamen Park, Seong-Lan Yu, Sungju Jee, Keun-Ah Cheon, Dong Ho Song, Seung Jun Kim, Woo-Young Im, Jaeku Kan. Effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) on spontaneously hypertensive rats, an animal model of attention-deficit/hyperactivity disorder. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 53. 2017-03-27. PMID:27469434. |
in the present study, we applied repetitive transcranial magnetic stimulation (rtms), a non-invasive treatment used in a number of other psychiatric disorders, to spontaneously hypertensive rats (shrs), an animal model of adhd, in order to assess the efficacy of the treatment in modifying behavioural symptoms as well as levels of dopamine, noradrenaline, serotonin, and brain-derived neurotrophic factor (bdnf). |
2017-03-27 |
2023-08-13 |
rat |