| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alesha Heath, Daniel R Lindberg, Kalina Makowiecki, Avalon Gray, Anders J Asp, Jennifer Rodger, Doo-Sup Choi, Paul E Croarki. Medium- and high-intensity rTMS reduces psychomotor agitation with distinct neurobiologic mechanisms. Translational psychiatry. vol 8. issue 1. 2019-02-04. PMID:29976924. |
behavioral effects were assessed with forced swim test; neurobiologic effects were assessed with brain levels of 5-hydroxytryptamine, brain-derived neurotrophic factor (bdnf), and neurogenesis. |
2019-02-04 |
2023-08-13 |
mouse |
| Giustino Orlando, Sheila Leone, Claudio Ferrante, Annalisa Chiavaroli, Adriano Mollica, Azzurra Stefanucci, Giorgia Macedonio, Marilisa Pia Dimmito, Lidia Leporini, Luigi Menghini, Luigi Brunetti, Lucia Recinell. Effects of Kisspeptin-10 on Hypothalamic Neuropeptides and Neurotransmitters Involved in Appetite Control. Molecules (Basel, Switzerland). vol 23. issue 12. 2019-01-29. PMID:30477219. |
in the present study, to characterize the role of hypothalamic kisspeptin as metabolic regulator, we evaluated the effects of kisspeptin-10 on neuropeptide y (npy) and brain-derived neurotrophic factor (bdnf) gene expression and the extracellular dopamine (da), norepinephrine (ne), serotonin (5-hydroxytriptamine, 5-ht), dihydroxyphenylacetic acid (dopac), and 5-hydroxyindoleacetic acid (5-hiia) concentrations in rat hypothalamic (hypo-e22) cells. |
2019-01-29 |
2023-08-13 |
rat |
| Giustino Orlando, Sheila Leone, Claudio Ferrante, Annalisa Chiavaroli, Adriano Mollica, Azzurra Stefanucci, Giorgia Macedonio, Marilisa Pia Dimmito, Lidia Leporini, Luigi Menghini, Luigi Brunetti, Lucia Recinell. Effects of Kisspeptin-10 on Hypothalamic Neuropeptides and Neurotransmitters Involved in Appetite Control. Molecules (Basel, Switzerland). vol 23. issue 12. 2019-01-29. PMID:30477219. |
in conclusion, our current findings suggesting the increased npy together with decreased bdnf and 5-ht activity following kisspeptin-10 would be consistent with a possible orexigenic effect induced by the peptide. |
2019-01-29 |
2023-08-13 |
rat |
| Yongtao Bai, Lihua Song, Guoliang Dai, Meijuan Xu, Lijing Zhu, Weidong Zhang, Wen Jing, Wenzheng J. Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection. Steroids. vol 135. 2018-12-11. PMID:29555480. |
moreover, we also found that cort levels in serum were significantly increased, along with the decrease of brain-derived neurotrophic factor (bdnf) mrna, bdnf protein, 5-hydroxytryptamine (5-ht) and norepinephrine (ne) levels in the hippocampus. |
2018-12-11 |
2023-08-13 |
mouse |
| Yongtao Bai, Lihua Song, Guoliang Dai, Meijuan Xu, Lijing Zhu, Weidong Zhang, Wen Jing, Wenzheng J. Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection. Steroids. vol 135. 2018-12-11. PMID:29555480. |
treatment with magnolol alleviated depressive-like behaviors, reduced the levels of cort, and improved the levels of bdnf protein, 5-ht, and ne compared with those in cort-treated mice. |
2018-12-11 |
2023-08-13 |
mouse |
| L Betti, L Palego, E Unti, S Mazzucchi, L Kiferle, G Palermo, U Bonuccelli, G Giannaccini, R Ceravol. Brain-Derived Neurotrophic Factor (BDNF) and Serotonin Transporter (SERT) in Platelets of Patients with Mild Huntington's Disease: Relationships with Social Cognition Symptoms. Archives italiennes de biologie. vol 156. issue 1-2. 2018-11-01. PMID:30039833. |
brain-derived neurotrophic factor (bdnf) and serotonin transporter (sert) in platelets of patients with mild huntington's disease: relationships with social cognition symptoms. |
2018-11-01 |
2023-08-13 |
human |
| L Betti, L Palego, E Unti, S Mazzucchi, L Kiferle, G Palermo, U Bonuccelli, G Giannaccini, R Ceravol. Brain-Derived Neurotrophic Factor (BDNF) and Serotonin Transporter (SERT) in Platelets of Patients with Mild Huntington's Disease: Relationships with Social Cognition Symptoms. Archives italiennes de biologie. vol 156. issue 1-2. 2018-11-01. PMID:30039833. |
since the neurotrophin brain-derived neurotrophic factor (bdnf) and the serotonin (5-ht) transporter (sert) are known to modulate human adaptive behavior, we appraised these two proteins in mild-hd using blood platelets, with the aim at finding relationships with cognitive/psychosocial skills. |
2018-11-01 |
2023-08-13 |
human |
| Xu-Bo Li, An Liu, Le Yang, Kun Zhang, Yu-Mei Wu, Ming-Gao Zhao, Shui-Bing Li. Antidepressant-like effects of translocator protein (18 kDa) ligand ZBD-2 in mouse models of postpartum depression. Molecular brain. vol 11. issue 1. 2018-10-22. PMID:29506545. |
the underlying mechanisms of zbd-2 were related to regulate the hypothalamic-pituitary-adrenal axis, enhance 5-ht and bdnf secretion, and maintain the excitatory and inhibitory synaptic protein expression to normal levels. |
2018-10-22 |
2023-08-13 |
mouse |
| Ze-Qun Li, Zhi-Yuan Yan, Fu-Jun Lan, Yi-Qun Dong, Ye Xion. Suppression of NLRP3 inflammasome attenuates stress-induced depression-like behavior in NLGN3-deficient mice. Biochemical and biophysical research communications. vol 501. issue 4. 2018-10-09. PMID:29775613. |
cums up-regulated corticosterone (cort) in serum, and down-regulated serotonin (5-ht), norepinephrine (ne) and brain-derived neurotrophic factor (bdnf) in hippocampus of mice, which were significantly reversed by nlgn3 deficiency. |
2018-10-09 |
2023-08-13 |
mouse |
| Kadri Andre, Olli Kampman, Merja Viikki, Eija Setälä-Soikkeli, Ari Illi, Nina Mononen, Terho Lehtimäki, Esa Leinone. BDNF and NRG1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression. Acta neuropsychiatrica. vol 30. issue 3. 2018-10-05. PMID:29310728. |
bdnf and nrg1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression. |
2018-10-05 |
2023-08-13 |
human |
| Kadri Andre, Olli Kampman, Merja Viikki, Eija Setälä-Soikkeli, Ari Illi, Nina Mononen, Terho Lehtimäki, Esa Leinone. BDNF and NRG1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression. Acta neuropsychiatrica. vol 30. issue 3. 2018-10-05. PMID:29310728. |
we investigated the separate effects of and possible interactions between the functional polymorphisms of brain-derived neurotrophic factor (bdnf) rs11030101, bdnf rs61888800, and neuregulin-1 (nrg1) rs3924999 and nrg1 rs6994992 on change of temperament scores in a clinical sample of subjects with major depression (mdd), who received selective serotonin reuptake inhibitor treatment for a period of 6 weeks. |
2018-10-05 |
2023-08-13 |
human |
| Jing Sun, Fangyan Wang, Xuezhen Hu, Changwei Yang, Hailing Xu, Ye Yao, Jiaming Li. Clostridium butyricum Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior in Mice via the Gut-Brain Axis. Journal of agricultural and food chemistry. vol 66. issue 31. 2018-08-20. PMID:30040410. |
the levels of cerebral 5-hydroxytryptamine (5-ht), brain derived neurotrophic factor (bdnf), glucagon-like peptide-1 (glp-1) receptor and intestinal were measured. |
2018-08-20 |
2023-08-13 |
mouse |
| Jing Sun, Fangyan Wang, Xuezhen Hu, Changwei Yang, Hailing Xu, Ye Yao, Jiaming Li. Clostridium butyricum Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior in Mice via the Gut-Brain Axis. Journal of agricultural and food chemistry. vol 66. issue 31. 2018-08-20. PMID:30040410. |
meanwhile, cb treatment exhibited prominent effects, increasing 5-ht and glp-1 and upregulating bdnf expression. |
2018-08-20 |
2023-08-13 |
mouse |
| Leandro Cattelan Souza, Cristiano R Jesse, Marcelo Gomes de Gomes, Lucian Del Fabbro, André Tiago Rossito Goes, Franciele Donato, Silvana Peterini Boeir. Activation of Brain Indoleamine-2,3-dioxygenase Contributes to Depressive-Like Behavior Induced by an Intracerebroventricular Injection of Streptozotocin in Mice. Neurochemical research. vol 42. issue 10. 2018-08-07. PMID:28631232. |
1-mt abrogates kynurenine production and normalizes brain-derived neurotrophic factor (bdnf) and the kynurenine/tryptophan ratio, but does not protect the biomarkers of the serotonin (5-ht) system in the hippocampus of stz-injected mice. |
2018-08-07 |
2023-08-13 |
mouse |
| Esfandiar Azadmarzabadi, Arvin Haghighatfard, Alireza Mohammad. Low resilience to stress is associated with candidate gene expression alterations in the dopaminergic signalling pathway. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 18. issue 3. 2018-08-01. PMID:29423959. |
here, we aimed to describe the association between comprehensive psychological characteristics and messenger rna levels of dopamine receptor d1 (drd1), dopamine receptor d2 (drd2), dopamine receptor d3 (drd3), dopamine receptor d4 (drd4), dopamine receptor d5 (drd5), comt, dopamine beta-hydroxylase (dbh), tyrosine hydroxylase (th), monoamine oxidase a (maom), dopa decarboxylase (ddc), dopamine transporter (dat), serotonin transporter (5-htt), brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) genes based on peripheral blood samples from 400 subjects who react differently to major life event stressors. |
2018-08-01 |
2023-08-13 |
human |
| Sally A Abuelezz, Nevien Hendawy, Yosra Magd. The potential benefit of combined versus monotherapy of coenzyme Q10 and fluoxetine on depressive-like behaviors and intermediates coupled to Gsk-3β in rats. Toxicology and applied pharmacology. vol 340. 2018-07-24. PMID:29291430. |
as a part of the serotoninergic dysfunction implicated in neurobiology of depression, evidence has focused on serotonin (5-ht) receptors downstream signaling intermediates including glycogen synthase kinase-3β (gsk-3β), camp response element binding protein (creb) and brain derived neurotrophic factor (bdnf). |
2018-07-24 |
2023-08-13 |
rat |
| Chih-Cheng Wu, Chih-Jen Hung, Shih-Yi Lin, Ya-Yu Wang, Cheng-Yi Chang, Wen-Ying Chen, Su-Lan Liao, Shue-Ling Raung, Ching-Ping Yang, Chun-Jung Che. Treadmill exercise alleviated prenatal buprenorphine exposure-induced depression in rats. Neurochemistry international. vol 110. 2018-06-06. PMID:28962922. |
prenatal buprenorphine exposure-induced neurobehavioral changes were accompanied by reductions of neuronal survival, neural stem cell-associated genes, plasma level of brain-derived neurotrophic factor (bdnf) and serotonin, phosphorylated tropomyosin-related kinase receptor type b (trkb), phosphorylated extracellular signal-regulated kinase (erk), pka activity, phosphorylated camp response element-binding protein (creb), and creb dna binding activity, as well as elevation of repressor element-1 silencing transcription factor (rest), oxidative stress, and inflammatory responses. |
2018-06-06 |
2023-08-13 |
rat |
| Liangcai Gao, Xinnan Liu, Li Yu, Junlin Wu, Mingchu Xu, Yusi Li. Folic acid exerts antidepressant effects by upregulating brain-derived neurotrophic factor and glutamate receptor 1 expression in brain. Neuroreport. vol 28. issue 16. 2018-06-04. PMID:28906345. |
then the changes of brain 5-hydroxytryptamine (5-ht) concentration, brain-derived neurotrophic factor (bdnf), glutamate receptor 1 (glur1) expression levels, and synaptic organization were assessed to explore the antidepressant mechanisms of folic acid. |
2018-06-04 |
2023-08-13 |
rat |
| Liangcai Gao, Xinnan Liu, Li Yu, Junlin Wu, Mingchu Xu, Yusi Li. Folic acid exerts antidepressant effects by upregulating brain-derived neurotrophic factor and glutamate receptor 1 expression in brain. Neuroreport. vol 28. issue 16. 2018-06-04. PMID:28906345. |
our results showed that cums caused significant depression-like behaviors, neuropathological changes, and decreased brain 5-ht concentration, bdnf, and glur1 expression in the hippocampus and association cortex. |
2018-06-04 |
2023-08-13 |
rat |
| Liangcai Gao, Xinnan Liu, Li Yu, Junlin Wu, Mingchu Xu, Yusi Li. Folic acid exerts antidepressant effects by upregulating brain-derived neurotrophic factor and glutamate receptor 1 expression in brain. Neuroreport. vol 28. issue 16. 2018-06-04. PMID:28906345. |
in conclusion, the results showed that folic acid significantly improved depression-like behaviors in cums-induced rats, and its antidepressant effects might be related to the increase of brain 5-ht concentration, bdnf and glur1 expression, and repair of synaptic organization in the brain. |
2018-06-04 |
2023-08-13 |
rat |