| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Sheldrick, S Camara, M Ilieva, P Riederer, T M Miche. Brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT3) levels in post-mortem brain tissue from patients with depression compared to healthy individuals - a proof of concept study. European psychiatry : the journal of the Association of European Psychiatrists. vol 46. 2018-05-18. PMID:29102768. |
therefore, we examined the concentration of brain-derived neurotrophic factor (bdnf) and neurotrophin 3 (nt3) in different brain regions (cortex, cingulate gyrus, thalamus, hippocampus, putamen and nucleus caudatus) of 21 individuals - 7 patients of which 4 patients with major depressive disorder (mdd) and overall age 86.8±5 years who received antidepressant pharmacotherapy (selective serotonin re-uptake inhibitors [ssri]; tricyclic antidepressants [tca]), 3 patients with mdd without antidepressant treatment and overall age 84.3±5 years versus 14 unaffected subjects at age 70.3±13.8. |
2018-05-18 |
2023-08-13 |
human |
| Vishnu N Thakare, Manoj K Aswar, Yogesh P Kulkarni, Rajesh R Patil, Bhoomika M Pate. Silymarin ameliorates experimentally induced depressive like behavior in rats: Involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response. Physiology & behavior. vol 179. 2018-05-01. PMID:28711395. |
behavioral (ambulatory and rearing activity and immobility time), neurochemical [serotonin (5-ht), dopamine (da), norepinephrine (ne) and brain derived neurotrophic factor (bdnf) level], biochemical (mda formation, il-6, tnf-α and antioxidants) changes in hippocampus and cerebral cortex along with serum corticosterone were investigated. |
2018-05-01 |
2023-08-13 |
mouse |
| Vishnu N Thakare, Manoj K Aswar, Yogesh P Kulkarni, Rajesh R Patil, Bhoomika M Pate. Silymarin ameliorates experimentally induced depressive like behavior in rats: Involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response. Physiology & behavior. vol 179. 2018-05-01. PMID:28711395. |
rats subjected to obx elicited significant increase in immobility time, ambulatory and rearing behaviors, reduced bdnf level, 5-ht, da, ne and antioxidant parameters along with increased serum corticosterone, mda formation, il-6, and tnf-α in hippocampus and cerebral cortex compared to sham operated rats. |
2018-05-01 |
2023-08-13 |
mouse |
| Vishnu N Thakare, Manoj K Aswar, Yogesh P Kulkarni, Rajesh R Patil, Bhoomika M Pate. Silymarin ameliorates experimentally induced depressive like behavior in rats: Involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response. Physiology & behavior. vol 179. 2018-05-01. PMID:28711395. |
administration of with silymarin significantly attenuated immobility time, ambulatory and rearing behaviors, serum corticosterone and improved bdnf expression, 5-ht, da, ne and antioxidant paradigms in cerebral cortex as well as hippocampus. |
2018-05-01 |
2023-08-13 |
mouse |
| Vishnu N Thakare, Manoj K Aswar, Yogesh P Kulkarni, Rajesh R Patil, Bhoomika M Pate. Silymarin ameliorates experimentally induced depressive like behavior in rats: Involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response. Physiology & behavior. vol 179. 2018-05-01. PMID:28711395. |
thus, silymarin exhibits anti-depressant-like activity in obx rats due to alterations in several neurotransmitters, endocrine and immunologic systems, including bdnf, 5-ht, da, ne, mda formation, il-6, and tnf-α in hippocampus and cerebral cortex as well as serum corticosterone. |
2018-05-01 |
2023-08-13 |
mouse |
| Moshe Gross, Emanuel Stanciu, Dvora Kenigsbuch-Sredni, Benjamin Sredni, Albert Pinhaso. The immunomodulatory tellurium compound ammonium trichloro (dioxoethylene-O,O') tellurate reduces anxiety-like behavior and corticosterone levels of submissive mice. Behavioural pharmacology. vol 28. issue 6. 2018-04-16. PMID:28590303. |
anxiolytic-like effects of as101 may be attributed to the modulation of the regulatory influence integrin of αvβ3 upon the serotonin transporter, suggesting a multifaceted mechanism by which as101 buffers the hypothalamic-pituitary-adrenal axis response to injection stress, enabling recovery of hippocampal bdnf expression and anxiety-like behavior in sub mice. |
2018-04-16 |
2023-08-13 |
mouse |
| Soledad Récamier-Carballo, Erika Estrada-Camarena, Carolina López-Rubalcav. Maternal separation induces long-term effects on monoamines and brain-derived neurotrophic factor levels on the frontal cortex, amygdala, and hippocampus: differential effects after a stress challenge. Behavioural pharmacology. vol 28. issue 7. 2018-04-16. PMID:28704274. |
the present study analyzed the effect of ms, in adult mice, on brain-derived neurotrophic factor (bdnf), serotonin (5-ht), and dopamine (da) levels, and the turnover rate in the hippocampus, frontal cortex, and amygdala, and brain regions that are associated with emotion. |
2018-04-16 |
2023-08-13 |
mouse |
| Soledad Récamier-Carballo, Erika Estrada-Camarena, Carolina López-Rubalcav. Maternal separation induces long-term effects on monoamines and brain-derived neurotrophic factor levels on the frontal cortex, amygdala, and hippocampus: differential effects after a stress challenge. Behavioural pharmacology. vol 28. issue 7. 2018-04-16. PMID:28704274. |
in ms mice, the three brain areas showed differential responses in 5-ht, da, and bdnf concentrations both in basal levels and when animals were challenged with an acute stressor in adulthood. |
2018-04-16 |
2023-08-13 |
mouse |
| Soledad Récamier-Carballo, Erika Estrada-Camarena, Carolina López-Rubalcav. Maternal separation induces long-term effects on monoamines and brain-derived neurotrophic factor levels on the frontal cortex, amygdala, and hippocampus: differential effects after a stress challenge. Behavioural pharmacology. vol 28. issue 7. 2018-04-16. PMID:28704274. |
finally, the hippocampus showed increased 5-ht and da activity, but not increased bdnf after the stress challenge in ms mice. |
2018-04-16 |
2023-08-13 |
mouse |
| Luca Borrelli, Serena Aceto, Claudio Agnisola, Sofia De Paolo, Ludovico Dipineto, Roman M Stilling, Timothy G Dinan, John F Cryan, Lucia F Menna, Alessandro Fiorett. Probiotic modulation of the microbiota-gut-brain axis and behaviour in zebrafish. Scientific reports. vol 6. 2018-04-12. PMID:27416816. |
animal studies reveal that gut bacteria influence behaviour, brain-derived neurotrophic factor (bdnf) levels and serotonin metabolism. |
2018-04-12 |
2023-08-13 |
zebrafish |
| Luca Borrelli, Serena Aceto, Claudio Agnisola, Sofia De Paolo, Ludovico Dipineto, Roman M Stilling, Timothy G Dinan, John F Cryan, Lucia F Menna, Alessandro Fiorett. Probiotic modulation of the microbiota-gut-brain axis and behaviour in zebrafish. Scientific reports. vol 6. 2018-04-12. PMID:27416816. |
after 28 days of dietary administration with the probiotic lactobacillus rhamnosus imc 501, we found differences in shoaling behaviour, brain expression levels of bdnf and of genes involved in serotonin signalling/metabolism between control and treated zebrafish group. |
2018-04-12 |
2023-08-13 |
zebrafish |
| Francesco Benedetti, Oliver Ambrée, Clara Locatelli, Cristina Lorenzi, Sara Poletti, Cristina Colombo, Volker Arol. The effect of childhood trauma on serum BDNF in bipolar depression is modulated by the serotonin promoter genotype. Neuroscience letters. vol 656. 2018-04-05. PMID:28754344. |
the effect of childhood trauma on serum bdnf in bipolar depression is modulated by the serotonin promoter genotype. |
2018-04-05 |
2023-08-13 |
human |
| Francesco Benedetti, Oliver Ambrée, Clara Locatelli, Cristina Lorenzi, Sara Poletti, Cristina Colombo, Volker Arol. The effect of childhood trauma on serum BDNF in bipolar depression is modulated by the serotonin promoter genotype. Neuroscience letters. vol 656. 2018-04-05. PMID:28754344. |
in healthy humans, both childhood trauma and the short form of the serotonin promoter transporter genotype (5-httlpr) are associated with lower levels of brain-derived neurotrophic factor (bdnf). |
2018-04-05 |
2023-08-13 |
human |
| Anindit Chhibber, Sarah K Woody, M A Karim Rumi, Michael J Soares, Liqin Zha. Estrogen receptor β deficiency impairs BDNF-5-HT Psychoneuroendocrinology. vol 82. 2018-04-03. PMID:28544903. |
in this study, the role of estrogen receptor (er) subtypes, erα and erβ, in the regulation of brain-derived neurotrophic factor (bdnf) and serotonin (5-ht) signaling was investigated; two pathways that have been hypothesized to be interrelated in the etiology of depression. |
2018-04-03 |
2023-08-13 |
Not clear |
| Akihiro Mouri, Yukihiro Noda, Minae Niwa, Yurie Matsumoto, Takayoshi Mamiya, Atsumi Nitta, Kiyofumi Yamada, Shoei Furukawa, Tatsunori Iwamura, Toshitaka Nabeshim. The involvement of brain-derived neurotrophic factor in 3,4-methylenedioxymethamphetamine-induced place preference and behavioral sensitization. Behavioural brain research. vol 329. 2018-03-15. PMID:28472632. |
mdma-induced place preference, behavioral sensitization, and an increase in the levels of extracellular serotonin and dopamine within the nucleus accumbens, were attenuated in bdnf heterozygous knockout mice. |
2018-03-15 |
2023-08-13 |
mouse |
| Philipp Hinderberger, Michael Rullmann, Mandy Drabe, Julia Luthardt, Georg-Alexander Becker, Matthias Blüher, Ralf Regenthal, Osama Sabri, Swen Hess. The effect of serum BDNF levels on central serotonin transporter availability in obese versus non-obese adults: A [(11)C]DASB positron emission tomography study. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27108933. |
the effect of serum bdnf levels on central serotonin transporter availability in obese versus non-obese adults: a [(11)c]dasb positron emission tomography study. |
2018-02-22 |
2023-08-13 |
human |
| Philipp Hinderberger, Michael Rullmann, Mandy Drabe, Julia Luthardt, Georg-Alexander Becker, Matthias Blüher, Ralf Regenthal, Osama Sabri, Swen Hess. The effect of serum BDNF levels on central serotonin transporter availability in obese versus non-obese adults: A [(11)C]DASB positron emission tomography study. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27108933. |
serotonin (5-ht) and its neurotrophic support system, specifically brain-derived neurotrophic factor (bdnf), are thought to modulate energy homeostasis and susceptibility to obesity. |
2018-02-22 |
2023-08-13 |
human |
| Qin Wu, Wei Yan, Houcheng Cheng, Chunsheng Liu, Tien-Chieh Hung, Xiaochun Guo, Guangyu L. Parental transfer of microcystin-LR induced transgenerational effects of developmental neurotoxicity in zebrafish offspring. Environmental pollution (Barking, Essex : 1987). vol 231. issue Pt 1. 2018-02-01. PMID:28837927. |
in addition, the acetylcholinesterase (ache) activity was remarkably decreased in mclr parental exposure groups, while the expression levels of manf, bdnf, ache, htr1ab, htr1b, htr2a, htr1aa, htr5a, dat, th1 and th2 genes coincided with the decreased content of neurotransmitters (dopamine, dopac and serotonin) and the activity of ache. |
2018-02-01 |
2023-08-13 |
zebrafish |
| Ronald S Duma. BDNF, 5-HT, and Anxiety: Identification of a Critical Periadolescent Developmental Period. The American journal of psychiatry. vol 174. issue 12. 2018-01-24. PMID:29191031. |
bdnf, 5-ht, and anxiety: identification of a critical periadolescent developmental period. |
2018-01-24 |
2023-08-13 |
Not clear |
| Kristen R Maynard, Julia L Hill, Nicholas E Calcaterra, Mary E Palko, Alisha Kardian, Daniel Paredes, Mahima Sukumar, Benjamin D Adler, Dennisse V Jimenez, Robert J Schloesser, Lino Tessarollo, Bai Lu, Keri Martinowic. Functional Role of BDNF Production from Unique Promoters in Aggression and Serotonin Signaling. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26585288. |
functional role of bdnf production from unique promoters in aggression and serotonin signaling. |
2018-01-15 |
2023-08-13 |
mouse |