| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Chandrasekhar, E M Ramya, K Navya, G Phani Kumar, K R Anilakuma. Antidepressant like effects of hydrolysable tannins of Terminalia catappa leaf extract via modulation of hippocampal plasticity and regulation of monoamine neurotransmitters subjected to chronic mild stress (CMS). Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 86. 2017-02-08. PMID:28012396. |
moreover, tc administration significantly restored cms induced changes in concentrations of hippocampal neurotransmitters (5-ht, da and ne) as well as levels of acetyl cholinesterase, cortisol, monoamine oxidases (mao-a, mao-b), bdnf, creb, and p-creb. |
2017-02-08 |
2023-08-13 |
mouse |
| Carlos Borges Filho, Cristiano Ricardo Jesse, Franciele Donato, Lucian Del Fabbro, Marcelo Gomes de Gomes, André Tiago Rossito Goes, Leandro Cattelan Souza, Silvana Peterini Boeir. Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice. Chemico-biological interactions. vol 260. 2017-01-31. PMID:27818124. |
ob also caused the elevation of tumor necrosis factor-α, interferon-γ, interleukin-1β, interleukin-6, kynurenine (kyn) levels and indoleamine-2,3-dioxygenase activity, as well as occasioned the decrease of 5-hydroxytryptamine (5-ht) and brain-derived neurotrophic factor (bdnf) levels and increase kyn/tryptophan and 5-hydroxyindoleacetic acid/5-ht ratio in the hippocampus. |
2017-01-31 |
2023-08-13 |
mouse |
| Golo Kronenberg, Valentina Mosienko, Karen Gertz, Natalia Alenina, Rainer Hellweg, Friederike Klempi. Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin. European archives of psychiatry and clinical neuroscience. vol 266. issue 3. 2016-12-21. PMID:26100147. |
increased brain-derived neurotrophic factor (bdnf) protein concentrations in mice lacking brain serotonin. |
2016-12-21 |
2023-08-13 |
mouse |
| Golo Kronenberg, Valentina Mosienko, Karen Gertz, Natalia Alenina, Rainer Hellweg, Friederike Klempi. Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin. European archives of psychiatry and clinical neuroscience. vol 266. issue 3. 2016-12-21. PMID:26100147. |
using a highly sensitive enzyme-linked immunosorbent assay, we studied bdnf concentrations in hippocampus and cortex of two mouse models of altered serotonin signaling: tryptophan hydroxylase (tph)2-deficient (tph2 (-/-)) mice lacking brain serotonin and serotonin transporter (sert)-deficient (sert(-/-)) mice lacking serotonin re-uptake. |
2016-12-21 |
2023-08-13 |
mouse |
| Golo Kronenberg, Valentina Mosienko, Karen Gertz, Natalia Alenina, Rainer Hellweg, Friederike Klempi. Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin. European archives of psychiatry and clinical neuroscience. vol 266. issue 3. 2016-12-21. PMID:26100147. |
our results emphasize the interaction between serotonin signaling and bdnf. |
2016-12-21 |
2023-08-13 |
mouse |
| Golo Kronenberg, Valentina Mosienko, Karen Gertz, Natalia Alenina, Rainer Hellweg, Friederike Klempi. Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin. European archives of psychiatry and clinical neuroscience. vol 266. issue 3. 2016-12-21. PMID:26100147. |
complete lack of brain serotonin induces bdnf expression. |
2016-12-21 |
2023-08-13 |
mouse |
| Kenji Hashimot. Regulation of brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain by serotonin. European archives of psychiatry and clinical neuroscience. vol 266. issue 3. 2016-12-21. PMID:26899501. |
regulation of brain-derived neurotrophic factor (bdnf) and its precursor probdnf in the brain by serotonin. |
2016-12-21 |
2023-08-13 |
Not clear |
| Yuan-Hwa Chou, Jiing-Feng Lirng, Wen-Chi Hsieh, Yen-Chen Chiu, Yi-An Tu, Shyh-Jen Wan. Neither cortisol nor brain-derived neurotrophic factor is associated with serotonin transporter in bipolar disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 2. 2016-12-13. PMID:26706694. |
the aim of this study was to examine the interaction of cortisol and bdnf on serotonin transporter (sert) in bipolar disorder (bd). |
2016-12-13 |
2023-08-13 |
human |
| Natalia Jaworska, Frank P MacMaster, Jane Foster, Rajamannar Ramasubb. The influence of 5-HTTLPR and Val66Met polymorphisms on cortical thickness and volume in limbic and paralimbic regions in depression: a preliminary study. BMC psychiatry. vol 16. 2016-10-19. PMID:26976307. |
among the various candidate genes implicated in mdd, the brain-derived neurotrophic factor (bdnf) val66met polymorphism and 5-ht transporter gene linked polymorphism (5-httlpr) have garnered the most attention due to their putative roles in neural plasticity and antidepressant response. |
2016-10-19 |
2023-08-13 |
Not clear |
| Rita Machaalani, Karen A Water. Neurochemical abnormalities in the brainstem of the Sudden Infant Death Syndrome (SIDS). Paediatric respiratory reviews. vol 15. issue 4. 2016-09-30. PMID:25304427. |
true to this hypothesis, data derived over the last 30 years shows that the brainstem of infants who died from sids exhibits abnormalities in a number of major neurotransmitter and receptor systems including: catecholamines, neuropeptides, acetylcholinergic, indole amines (predominantly serotonin and its receptors), amino acids (predominantly glutamate), brain derived neurotrophic growth factor (bdnf), and some cytokines. |
2016-09-30 |
2023-08-13 |
Not clear |
| Yeshwant Kurhe, Radhakrishnan Mahes. Mechanisms linking depression co-morbid with obesity: An approach for serotonergic type 3 receptor antagonist as novel therapeutic intervention. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26243683. |
furthermore, serotonin regulates diet intake, leptin, corticosterone, inflammatory mechanisms, altered plasma glucose, insulin resistance and bdnf concentration in brain. |
2016-09-28 |
2023-08-13 |
Not clear |
| Ying-pan Zhao, Min Su, Feng-yun Wang, Zhao-xiang Bian, Jian-qin Yang, Wei Wang, Xu-dong Tan. [Effect of Chang'an No. I Recipe on 5-hydroxytryptamine Signal System and mRNA Expression Levels of Hippocampal Brain Derived Neurotrophic Factor in Visceral Hypersensitivity Rats with Irritable Bowel Syndrome]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 35. issue 10. 2016-09-15. PMID:26677676. |
i recipe (ca) on 5-hydroxytryptamine signal system and mrna expression levels of hippocampal brain derived neurotrophic factor (bdnf) in visceral hypersensitivity model rats with irritable bowel syndrome (ibs). |
2016-09-15 |
2023-08-13 |
rat |
| Roodabeh Bahramsoltani, Mohammad Hosein Farzaei, Marzieh Sarbandi Farahani, Roja Rahim. Phytochemical constituents as future antidepressants: a comprehensive review. Reviews in the neurosciences. vol 26. issue 6. 2016-09-09. PMID:26146123. |
naringenin has represented its antidepressant effect by elevation of serotonin (5-ht), norepinephrine, brain-derived neurotrophic factor (bdnf), and glucocorticoid receptors. |
2016-09-09 |
2023-08-13 |
Not clear |
| Roodabeh Bahramsoltani, Mohammad Hosein Farzaei, Marzieh Sarbandi Farahani, Roja Rahim. Phytochemical constituents as future antidepressants: a comprehensive review. Reviews in the neurosciences. vol 26. issue 6. 2016-09-09. PMID:26146123. |
piperine demonstrated inhibition of monoamine oxidase enzymes, elevation of brain 5-ht and bdnf levels, and modulation of the hypothalamus-pituitary-adrenal axis. |
2016-09-09 |
2023-08-13 |
Not clear |
| Elizabeth Hitchner, Doug Morrison, Phoebe Liao, Allyson Rosen, Wei Zho. Genetic Polymorphisms Influence Cognition in Patients Undergoing Carotid Interventions. The International journal of angiology : official publication of the International College of Angiology, Inc. vol 25. issue 3. 2016-08-30. PMID:27574384. |
after correcting for age and genetic polymorphisms in bdnf and serotonin transporter (5-htt), apoe 4 allele was associated with depression (p= 0.044) and showed a trend with baseline cognitive impairment (p= 0.10). |
2016-08-30 |
2023-08-13 |
Not clear |
| Giuseppe Musumeci, Paola Castrogiovanni, Sergio Castorina, Rosa Imbesi, Marta Anna Szychlinska, Soraya Scuderi, Carla Loreto, Salvatore Giunt. Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet. Brain research bulletin. vol 119. issue Pt A. 2016-08-29. PMID:26444078. |
since 5-ht is closely associated to bdnf, we aimed to investigate the effect of high trp diet on 5-ht levels and bdnf expression in frontal cortex (fc) and hippocampus (hp) of aged rats. |
2016-08-29 |
2023-08-13 |
rat |
| Giuseppe Musumeci, Paola Castrogiovanni, Sergio Castorina, Rosa Imbesi, Marta Anna Szychlinska, Soraya Scuderi, Carla Loreto, Salvatore Giunt. Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet. Brain research bulletin. vol 119. issue Pt A. 2016-08-29. PMID:26444078. |
we found that the raising of systemic 5-ht levels by chronic diet (1 month) containing high trp significantly prevents age-related decline of bdnf protein expression in both brain areas as indicated by elisa and western blot analyses. |
2016-08-29 |
2023-08-13 |
rat |
| Giuseppe Musumeci, Paola Castrogiovanni, Sergio Castorina, Rosa Imbesi, Marta Anna Szychlinska, Soraya Scuderi, Carla Loreto, Salvatore Giunt. Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet. Brain research bulletin. vol 119. issue Pt A. 2016-08-29. PMID:26444078. |
interestingly, immunohistochemical analyses confirmed that high trp diet significantly elevates the number of 5-ht immunoreactive fibers in both brain areas tested and this correlated with bdnf increase in the fc and hippocampal regions ca1, ca2, ca3 and a strikingly down-regulation of neurotrophin levels in the dentate gyrus (dg) of aged rats. |
2016-08-29 |
2023-08-13 |
rat |
| Giuseppe Musumeci, Paola Castrogiovanni, Sergio Castorina, Rosa Imbesi, Marta Anna Szychlinska, Soraya Scuderi, Carla Loreto, Salvatore Giunt. Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet. Brain research bulletin. vol 119. issue Pt A. 2016-08-29. PMID:26444078. |
altogether, these finding provide evidence that enhanced trp intake and the consequent increase in 5-ht neurotransmission may act as a modulator of bdnf system suggesting a possible mechanism for the protective role of serotonergic system on memory impairment occurring along normal aging process. |
2016-08-29 |
2023-08-13 |
rat |
| Jing Sun, Fangyan Wang, Guangliang Hong, Mengqi Pang, Hailing Xu, Haixiao Li, Feng Tian, Renchi Fang, Ye Yao, Jiaming Li. Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. Neuroscience letters. vol 618. 2016-08-22. PMID:26957230. |
then changes of nissl's body in the hippocampus, brain serotonin (5-ht) concentration, brain-derived neurotrophic factor (bdnf) and tight junctions (tjs) proteins level were assessed to explore the antidepressant mechanisms. |
2016-08-22 |
2023-08-13 |
mouse |