| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seiko Yasuda, Mitsuhiro Yoshida, Hirotaka Yamagata, Yasutake Iwanaga, Hiromi Suenaga, Kozo Ishikawa, Masako Nakano, Satoshi Okuyama, Yoshiko Furukawa, Shoei Furukawa, Toshizo Ishikaw. Imipramine ameliorates pain-related negative emotion via induction of brain-derived neurotrophic factor. Cellular and molecular neurobiology. vol 34. issue 8. 2015-06-10. PMID:25156823. |
changes in perk1/2 (immunohistochemistry), 5-ht and bdnf (elisa), and bdnf mrna (rt-pcr) were measured in the anterior cingulate cortex (acc), rostral ventromedial medulla (rvm), and spinal cord. |
2015-06-10 |
2023-08-13 |
rat |
| Seiko Yasuda, Mitsuhiro Yoshida, Hirotaka Yamagata, Yasutake Iwanaga, Hiromi Suenaga, Kozo Ishikawa, Masako Nakano, Satoshi Okuyama, Yoshiko Furukawa, Shoei Furukawa, Toshizo Ishikaw. Imipramine ameliorates pain-related negative emotion via induction of brain-derived neurotrophic factor. Cellular and molecular neurobiology. vol 34. issue 8. 2015-06-10. PMID:25156823. |
this suggests a possible interaction between 5-ht and bdnf. |
2015-06-10 |
2023-08-13 |
rat |
| Dongmei Duan, Liping Chen, Xiuyan Yang, Ya Tu, Shuang Jia. Antidepressant-like effect of essential oil isolated from Toona ciliata Roem. var. yunnanensis. Journal of natural medicines. vol 69. issue 2. 2015-06-02. PMID:25465853. |
additionally, the contents of da, ne, 5-ht, and bdnf in the hippocampus of cms rats could be increased by treatment with essential oil at doses of 20, 40, and 80 mg/kg. |
2015-06-02 |
2023-08-13 |
rat |
| Hiromi I Weston, Douglas D Weston, Joshua L Allen, Deborah A Cory-Slecht. Sex-dependent impacts of low-level lead exposure and prenatal stress on impulsive choice behavior and associated biochemical and neurochemical manifestations. Neurotoxicology. vol 44. 2015-05-27. PMID:25010656. |
brains of littermates of behaviorally-trained offspring were utilized to examine corresponding changes in monoamines and in levels of brain derived neurotrophic factor (bdnf), the serotonin transporter (sert) and the n-methyl-d-aspartate receptor (nmdar) 2a in brain regions associated with impulsive choice behavior. |
2015-05-27 |
2023-08-13 |
rat |
| Hiromi I Weston, Douglas D Weston, Joshua L Allen, Deborah A Cory-Slecht. Sex-dependent impacts of low-level lead exposure and prenatal stress on impulsive choice behavior and associated biochemical and neurochemical manifestations. Neurotoxicology. vol 44. 2015-05-27. PMID:25010656. |
consistent with these behavioral changes, pb±ps treated males also showed reductions in brain serotonin function in all mesocorticolimbic regions, broad monoamine changes in nucleus accumbens, and reductions in both bdnf and nmdar 2a levels and increases in sert in frontal cortex, i.e., in regions and neurotransmitter systems known to mediate learning/behavioral flexibility, and which were of greater impact in males. |
2015-05-27 |
2023-08-13 |
rat |
| Wen-Jing Yan, Ying-Chun Tan, Ji-Cheng Xu, Xian-Ping Tang, Chong Zhang, Peng-Bo Zhang, Ze-Qiang Re. Protective effects of silibinin and its possible mechanism of action in mice exposed to chronic unpredictable mild stress. Biomolecules & therapeutics. vol 23. issue 3. 2015-05-21. PMID:25995823. |
furthermore, silibinin treatment increased the levels of brain-derived neurotrophic factor (bdnf), serotonin (5-ht) and norepinephrine (ne) in the prefrontal cortex and hippocampus. |
2015-05-21 |
2023-08-13 |
mouse |
| Keith Bredemeier, Christopher G Beevers, John E McGear. Serotonin transporter and BDNF polymorphisms interact to predict trait worry. Anxiety, stress, and coping. vol 27. issue 6. 2015-05-15. PMID:24679122. |
serotonin transporter and bdnf polymorphisms interact to predict trait worry. |
2015-05-15 |
2023-08-12 |
Not clear |
| A S Tsybko, T V Il'chibaeva, E M Kondaurova, D V Bazovkina, V S Naumenk. [The effect of central administration of the neurotrophic factors BDNF and GDNF on the functional activity and expression of the serotonin 5-HT2A receptors in mice genetically predisposed to depressive-like behavior]. Molekuliarnaia biologiia. vol 48. issue 6. 2015-04-17. PMID:25845239. |
[the effect of central administration of the neurotrophic factors bdnf and gdnf on the functional activity and expression of the serotonin 5-ht2a receptors in mice genetically predisposed to depressive-like behavior]. |
2015-04-17 |
2023-08-13 |
mouse |
| Rameswar Pal, Som Nath Singh, Abhirup Chatterjee, Mantu Sah. Age-related changes in cardiovascular system, autonomic functions, and levels of BDNF of healthy active males: role of yogic practice. Age (Dordrecht, Netherlands). vol 36. issue 4. 2015-03-31. PMID:25012275. |
bdnf, serotonin, and dopamine were low in higher age group. |
2015-03-31 |
2023-08-13 |
Not clear |
| Rameswar Pal, Som Nath Singh, Abhirup Chatterjee, Mantu Sah. Age-related changes in cardiovascular system, autonomic functions, and levels of BDNF of healthy active males: role of yogic practice. Age (Dordrecht, Netherlands). vol 36. issue 4. 2015-03-31. PMID:25012275. |
significant decrement of cortisol; acth; and increment in serotonin, dopamine, and bdnf was noted following yogic practice. |
2015-03-31 |
2023-08-13 |
Not clear |
| Erika Comasco, Andreas Hahn, Sebastian Ganger, Malin Gingnell, Elin Bannbers, Lars Oreland, Johan Wikström, C Neill Epperson, Rupert Lanzenberger, Inger Sundström-Poroma. Emotional fronto-cingulate cortex activation and brain derived neurotrophic factor polymorphism in premenstrual dysphoric disorder. Human brain mapping. vol 35. issue 9. 2015-03-06. PMID:24615932. |
the present study investigated brain emotion processing in pmdd and healthy controls, as well as functional polymorphisms in two candidate genes for pmdd, the serotonin transporter (5-htt) and brain derived neurotrophic factor (bdnf). |
2015-03-06 |
2023-08-12 |
Not clear |
| Judith Regina Homberg, Raffaella Molteni, Francesca Calabrese, Marco A Riv. The serotonin-BDNF duo: developmental implications for the vulnerability to psychopathology. Neuroscience and biobehavioral reviews. vol 43. 2015-02-27. PMID:24704572. |
serotonin (5-ht) and brain-derived neurotrophin factor (bdnf) are known to modulate behavioral responses to stress and to mediate the therapeutic efficacy of antidepressant agents through neuroplastic and epigenetic mechanisms. |
2015-02-27 |
2023-08-13 |
human |
| Judith Regina Homberg, Raffaella Molteni, Francesca Calabrese, Marco A Riv. The serotonin-BDNF duo: developmental implications for the vulnerability to psychopathology. Neuroscience and biobehavioral reviews. vol 43. 2015-02-27. PMID:24704572. |
5-htt knockout in rats, as well as the low activity short allelic variant of the serotonin transporter human polymorphism, consistently show reduced bdnf mrna and protein levels in the hippocampus and in the prefrontal cortex. |
2015-02-27 |
2023-08-13 |
human |
| J W Lunden, L G Kirb. Opiate exposure and withdrawal dynamically regulate mRNA expression in the serotonergic dorsal raphe nucleus. Neuroscience. vol 254. 2015-02-23. PMID:24055683. |
gene expression for brain-derived neurotrophic factor (bdnf), tyrosine kinase receptor b (trkb), corticotrophin releasing-factor (crf)-r1, crf-r2, alpha 1 subunit of the gabaa receptor (gabaa-α1), μ-opioid receptor (mor), 5-ht1a receptor, tryptophan hydroxylase2 (tph2) and the 5-ht transporter was then measured using quantitative real-time polymerase chain reaction at multiple time-points across the model of morphine exposure, withdrawal and post withdrawal stress. |
2015-02-23 |
2023-08-12 |
rat |
| Vladimir S Naumenko, Elena M Kondaurova, Daria V Bazovkina, Anton S Tsybko, Tatyana V Il'chibaeva, Nina K Popov. On the role of 5-HT(1A) receptor gene in behavioral effect of brain-derived neurotrophic factor. Journal of neuroscience research. vol 92. issue 8. 2015-02-21. PMID:24706292. |
however, bdnf failed to produce any effect on the expression of 5-ht(1a) , 5-ht(2a) , and tph-2 genes in 76c mice but decreased functional activity of 5-ht(2a) receptors in 76c mice and increased it in akr mice. |
2015-02-21 |
2023-08-13 |
mouse |
| Vladimir S Naumenko, Elena M Kondaurova, Daria V Bazovkina, Anton S Tsybko, Tatyana V Il'chibaeva, Nina K Popov. On the role of 5-HT(1A) receptor gene in behavioral effect of brain-derived neurotrophic factor. Journal of neuroscience research. vol 92. issue 8. 2015-02-21. PMID:24706292. |
the data indicate that a small genetic variation altered the response to bdnf and show an important role of 5-ht(1a) receptor gene in the 5-ht system response to bdnf treatment and in behavioral effects of bdnf. |
2015-02-21 |
2023-08-13 |
mouse |
| Andrey Sequeira-Cordero, Andrea Mora-Gallegos, Patricia Cuenca-Berger, Jaime Fornaguera-Tría. Individual differences in the forced swimming test and neurochemical kinetics in the rat brain. Physiology & behavior. vol 128. 2015-02-19. PMID:24518862. |
we analyzed the expression of the crf, crfr1, bdnf and trkb in the prefrontal cortex, hippocampus and nucleus accumbens as well as norepinephrine, dopamine, serotonin, glutamate, gaba and glutamine in the hippocampus and nucleus accumbens. |
2015-02-19 |
2023-08-12 |
rat |
| Francesca Calabrese, Rick H A van der Doelen, Gianluigi Guidotti, Giorgio Racagni, Tamas Kozicz, Judith R Homberg, Marco A Riv. Exposure to early life stress regulates Bdnf expression in SERT mutant rats in an anatomically selective fashion. Journal of neurochemistry. vol 132. issue 1. 2015-02-19. PMID:25087780. |
in this study, we investigated the impact of chronic maternal separation (ms) on the expression of the neurotrophin brain-derived neurotrophic factor (bdnf) in serotonin transporter (sert) knockout rats in the ventral and dorsal hippocampus as well as the ventromedial and dorsomedial prefrontal cortex (pfc). |
2015-02-19 |
2023-08-13 |
rat |
| Qing-Qiu Mao, Zhen Huang, Xiao-Ming Zhong, Yan-Fang Xian, Siu-Po I. Piperine reverses chronic unpredictable mild stress-induced behavioral and biochemical alterations in rats. Cellular and molecular neurobiology. vol 34. issue 3. 2015-02-12. PMID:24401942. |
in addition, it was found that serotonin (5-ht) and brain-derived neurotrophic factor (bdnf) contents in the hippocampus and frontal cortex were significantly decreased in cums-treated rats. |
2015-02-12 |
2023-08-12 |
mouse |
| Qing-Qiu Mao, Zhen Huang, Xiao-Ming Zhong, Yan-Fang Xian, Siu-Po I. Piperine reverses chronic unpredictable mild stress-induced behavioral and biochemical alterations in rats. Cellular and molecular neurobiology. vol 34. issue 3. 2015-02-12. PMID:24401942. |
the results suggest that piperine produces an antidepressant-like effect in cums-treated rats, which is possibly mediated by increasing 5-ht and bdnf contents in selective brain tissues. |
2015-02-12 |
2023-08-12 |
mouse |