| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manuel Kuhn, Ana Popovic, Lukas Pezawa. Neuroplasticity and memory formation in major depressive disorder: an imaging genetics perspective on serotonin and BDNF. Restorative neurology and neuroscience. vol 32. issue 1. 2014-09-19. PMID:23603442. |
neuroplasticity and memory formation in major depressive disorder: an imaging genetics perspective on serotonin and bdnf. |
2014-09-19 |
2023-08-12 |
human |
| Manuel Kuhn, Ana Popovic, Lukas Pezawa. Neuroplasticity and memory formation in major depressive disorder: an imaging genetics perspective on serotonin and BDNF. Restorative neurology and neuroscience. vol 32. issue 1. 2014-09-19. PMID:23603442. |
a vast number of imaging studies have demonstrated the impact of serotonin (5-ht) and brain-derived neurotrophic factor (bdnf) on emotion and memory-related networks in the context of major depressive disorder (mdd). |
2014-09-19 |
2023-08-12 |
human |
| Manuel Kuhn, Ana Popovic, Lukas Pezawa. Neuroplasticity and memory formation in major depressive disorder: an imaging genetics perspective on serotonin and BDNF. Restorative neurology and neuroscience. vol 32. issue 1. 2014-09-19. PMID:23603442. |
the crucial role of 5-ht and bdnf signaling in the context of mdd is reflected in the etiologic models of mdd such as the monoamine or neuroplasticity hypothesis as well as in pharmacological models of antidepressant response. |
2014-09-19 |
2023-08-12 |
human |
| Manuel Kuhn, Ana Popovic, Lukas Pezawa. Neuroplasticity and memory formation in major depressive disorder: an imaging genetics perspective on serotonin and BDNF. Restorative neurology and neuroscience. vol 32. issue 1. 2014-09-19. PMID:23603442. |
in this review, which focuses on neuroimaging studies in the context of mdd, the authors will provide a comprehensive overview of these networks as well as on the specific role of 5-ht and bdnf in their development and function. |
2014-09-19 |
2023-08-12 |
human |
| Claudia Pudell, Bianca A Vicente, Ana M Delattre, Bruno Carabelli, Marco A Mori, Deborah Suchecki, Ricardo B Machado, Sílvio M Zanata, Jesuí V Visentainer, Oscar de Oliveira Santos Junior, Marcelo M S Lima, Anete C Ferra. Fish oil improves anxiety-like, depressive-like and cognitive behaviors in olfactory bulbectomised rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24191918. |
female rats received supplementation with fo during habituation, mating, gestation, and lactation, and their pups were subjected to obx in adulthood; after the recovery period, the adult offspring were subjected to behavioral tests, and the hippocampal levels of brain-derived neurotrophic factor (bdnf), serotonin (5-ht) and the metabolite 5-hydroxyindoleacetic (5-hiaa) were determined. |
2014-09-03 |
2023-08-12 |
rat |
| Claudia Pudell, Bianca A Vicente, Ana M Delattre, Bruno Carabelli, Marco A Mori, Deborah Suchecki, Ricardo B Machado, Sílvio M Zanata, Jesuí V Visentainer, Oscar de Oliveira Santos Junior, Marcelo M S Lima, Anete C Ferra. Fish oil improves anxiety-like, depressive-like and cognitive behaviors in olfactory bulbectomised rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24191918. |
obx caused reductions in the levels of hippocampal bdnf and 5-ht, whereas fo supplementation restored these levels to normal values. |
2014-09-03 |
2023-08-12 |
rat |
| Claudia Pudell, Bianca A Vicente, Ana M Delattre, Bruno Carabelli, Marco A Mori, Deborah Suchecki, Ricardo B Machado, Sílvio M Zanata, Jesuí V Visentainer, Oscar de Oliveira Santos Junior, Marcelo M S Lima, Anete C Ferra. Fish oil improves anxiety-like, depressive-like and cognitive behaviors in olfactory bulbectomised rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24191918. |
these results may be explained by increased levels of hippocampal bdnf and 5-ht, two major regulators of neuronal survival and long-term plasticity in this brain structure. |
2014-09-03 |
2023-08-12 |
rat |
| Moseon Lee, Woongjoon Moon, Jaehee Ki. Effect of yoga on pain, brain-derived neurotrophic factor, and serotonin in premenopausal women with chronic low back pain. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-08-14. PMID:25120574. |
serotonin and brain-derived neurotrophic factor (bdnf) are known to be modulators of nociception. |
2014-08-14 |
2023-08-13 |
Not clear |
| Moseon Lee, Woongjoon Moon, Jaehee Ki. Effect of yoga on pain, brain-derived neurotrophic factor, and serotonin in premenopausal women with chronic low back pain. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-08-14. PMID:25120574. |
therefore, we aimed to evaluate the effect of yoga on pain, bdnf, and serotonin. |
2014-08-14 |
2023-08-13 |
Not clear |
| Moseon Lee, Woongjoon Moon, Jaehee Ki. Effect of yoga on pain, brain-derived neurotrophic factor, and serotonin in premenopausal women with chronic low back pain. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-08-14. PMID:25120574. |
at baseline and after 12 weeks, back pain intensity was measured using visual analogue scale (vas), and serum bdnf and serotonin levels were evaluated. |
2014-08-14 |
2023-08-13 |
Not clear |
| Tyra S C Zetterström, Alexander A Coppell, Ahmad A Khundaka. The role of 5-hydroxytryptamine receptor subtypes in the regulation of brain-derived neurotrophic factor gene expression. The Journal of pharmacy and pharmacology. vol 66. issue 1. 2014-08-05. PMID:24341949. |
the study aims to investigate the role of 5-hydroxytryptamine receptor subtypes in mediating the inhibitory effect of the selective serotonin reuptake inhibitor (fluoxetine on brain-derived neurotrophic factor gene (bdnf) expression in rat hippocampus. |
2014-08-05 |
2023-08-12 |
rat |
| Rudolf Uhe. Gene-environment interactions in common mental disorders: an update and strategy for a genome-wide search. Social psychiatry and psychiatric epidemiology. vol 49. issue 1. 2014-07-28. PMID:24323294. |
specific and complementary roles of genetic factors have been delineated: a common functional length polymorphism in the serotonin transporter gene (5-httlpr) moderated the effect of childhood maltreatment on chronic depression in adulthood, but did not substantially influence the effects of adult stressful life events on the onset of new depressive episodes; in contrast, a common functional polymorphism in the brain-derived neurotrophic factor gene (bdnf) moderated the effect of stressful life events in adulthood in triggering new depressive episodes, but did not influence the effects of childhood maltreatment. |
2014-07-28 |
2023-08-12 |
Not clear |
| Liang-Jen Wang, Chih-Ken Chen, Heng-Jung Hsu, I-Wen Wu, Chiao-Yin Sun, Chin-Chan Le. Depression, 5HTTLPR and BDNF Val66Met polymorphisms, and plasma BDNF levels in hemodialysis patients with chronic renal failure. Neuropsychiatric disease and treatment. vol 10. 2014-07-21. PMID:25045267. |
this cross-sectional study investigated whether depression in hemodialysis patients is associated with the polymorphism of the 5' flanking transcriptional region (5-httlpr) of the serotonin transporter gene, the valine (val)-to-methionine (met) substitution at codon 66 (val66met) polymorphism of the brain-derived neurotrophic factor (bdnf) gene, or plasma bdnf levels. |
2014-07-21 |
2023-08-13 |
Not clear |
| Aleksandra Szczepankiewic. Evidence for single nucleotide polymorphisms and their association with bipolar disorder. Neuropsychiatric disease and treatment. vol 9. 2014-06-24. PMID:24143106. |
the review of association data reveals evidence for several genes (slc6a4/5-htt [serotonin transporter gene], bdnf [brain-derived neurotrophic factor], daoa [d-amino acid oxidase activator], dtnbp1 [dysbindin], nrg1 [neuregulin 1], disc1 [disrupted in schizophrenia 1]) to be crucial candidates in bd, whereas numerous genome-wide association studies conducted in bd indicate polymorphisms in two genes (cacna1c [calcium channel, voltage-dependent, l type, alpha 1c subunit], ank3 [ankyrin 3]) replicated for association with bd in most of these studies. |
2014-06-24 |
2023-08-12 |
Not clear |
| Oscar Andrés Moreno-Ramos, Maria Claudia Lattig, Andrés Fernando González Barrio. Modeling of the hypothalamic-pituitary-adrenal axis-mediated interaction between the serotonin regulation pathway and the stress response using a Boolean approximation: a novel study of depression. Theoretical biology & medical modelling. vol 10. 2014-06-18. PMID:24093582. |
this work also predicted that the genes with the greatest impact on model stability were those involved in the neurotrophin pathway, such as creb, bdnf (which has been associated with major depressive disorder in a variety of studies) and trkb, followed by genes and metabolites related to 5-ht synthesis. |
2014-06-18 |
2023-08-12 |
Not clear |
| Elham H A Ali, Amany H Mahmoud Elgol. Combined prenatal and postnatal butyl paraben exposure produces autism-like symptoms in offspring: comparison with valproic acid autistic model. Pharmacology, biochemistry, and behavior. vol 111. 2014-06-13. PMID:24036472. |
the offspring male rats were subjected at the last 3 days of lactation to morris water maze and three chamber sociability test then decapitated and the brain was excised and dissected to the cortex, hippocampus, cerebellum, midbrain and pons for the determination of norepinephrine, dopamine and serotonin (ne, da and 5-ht) and cortex amino acids and whole brain bdnf. |
2014-06-13 |
2023-08-12 |
rat |
| S Migliarini, G Pacini, B Pelosi, G Lunardi, M Pasqualett. Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23007167. |
finally, we demonstrated that bdnf expression is significantly up-regulated in the hippocampus of mice lacking brain 5-ht, mirroring the timing of the appearance of hyperinnervation and thus unmasking a possible regulatory feedback mechanism tuning the serotonergic neuronal circuitry formation. |
2014-05-29 |
2023-08-12 |
mouse |
| Annette M La Greca, Betty S Lai, Jutta Joormann, Beth B Auslander, Mary A Shor. Children's risk and resilience following a natural disaster: genetic vulnerability, posttraumatic stress, and depression. Journal of affective disorders. vol 151. issue 3. 2014-05-21. PMID:24035489. |
we examined children's risk and resilience following a natural disaster, evaluating the role of stress, social support, and two genetic markers: the short allele of the serotonin transporter gene (5-httlpr), and the met allele of the brain-derived neurotrophic factor (bdnf).under high levels of hurricane exposure or hurricane-related stressors, we expected children displaying the markers would report greater symptoms of posttraumatic stress disorder (ptsd) and depression than children without these markers. |
2014-05-21 |
2023-08-12 |
Not clear |
| Kyu Young Lee, Seong Hoon Jeong, Se Hyun Kim, Yong Min Ahn, Yong Sik Kim, Hee Yeon Jung, Yang Weon Bang, Eun-Jeong Jo. Genetic Role of BDNF Val66Met and 5-HTTLPR Polymorphisms on Depressive Disorder. Psychiatry investigation. vol 11. issue 2. 2014-05-20. PMID:24843376. |
brain derived neurotrophic factor (bdnf) gene and serotonin transporter (slc6a4) gene are promising candidate genes for depressive disorders. |
2014-05-20 |
2023-08-13 |
Not clear |
| Niki Kourmouli, Maria Samakouri, Athina Mamatsiou, Gregory Trypsianis, Miltos Livaditis, Stavroula Veletz. Effect of BDNF Val66Met and serotonin transporter 5-HTTLPR polymorphisms on psychopathological characteristics in a sample of university students. Psychiatric genetics. vol 23. issue 5. 2014-05-19. PMID:23884433. |
effect of bdnf val66met and serotonin transporter 5-httlpr polymorphisms on psychopathological characteristics in a sample of university students. |
2014-05-19 |
2023-08-12 |
Not clear |