| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V S Naumenko, E M Kondaurova, D V Bazovkina, A S Tsybko, M A Tikhonova, A V Kulikov, N K Popov. Effect of brain-derived neurotrophic factor on behavior and key members of the brain serotonin system in genetically predisposed to behavioral disorders mouse strains. Neuroscience. vol 214. 2013-04-29. PMID:22531372. |
it was shown that central administration of bdnf led to increase of 5-ht(1a) receptor gene expression but not 5-ht(1a) functional activity in asc mice. |
2013-04-29 |
2023-08-12 |
mouse |
| V S Naumenko, E M Kondaurova, D V Bazovkina, A S Tsybko, M A Tikhonova, A V Kulikov, N K Popov. Effect of brain-derived neurotrophic factor on behavior and key members of the brain serotonin system in genetically predisposed to behavioral disorders mouse strains. Neuroscience. vol 214. 2013-04-29. PMID:22531372. |
in conclusion, central administration of bdnf produced prolonged ameliorative effect on depressive-like behavior accompanied by increase of the tph-2, 5-ht(1a) and 5-ht(2a) genes expression and 5-ht(2a) receptor functional activity in animal model of hereditary behavior disorders. |
2013-04-29 |
2023-08-12 |
mouse |
| Maria E Czira, Heike Wersching, Bernhard T Baune, Klaus Berge. Brain-derived neurotrophic factor gene polymorphisms, neurotransmitter levels, and depressive symptoms in an elderly population. Age (Dordrecht, Netherlands). vol 34. issue 6. 2013-04-24. PMID:21898033. |
the present study aims to examine the association between three common bdnf single-nucleotid polymorphisms (snps; rs7103411, rs7124442, and rs6265) and depressive symptoms in a community-based elderly population taking into account the serum levels of four neurotransmitters, serotonin, dopamine, adrenalin, and noradrenalin, as potential mediating factors. |
2013-04-24 |
2023-08-12 |
Not clear |
| Sevtap Savas, Angela Hyde, Susan N Stuckless, Patrick Parfrey, H Banfield Younghusband, Roger Gree. Serotonin transporter gene (SLC6A4) variations are associated with poor survival in colorectal cancer patients. PloS one. vol 7. issue 7. 2013-04-19. PMID:22911682. |
in the present study, we hypothesize that genetic variations within three genes biologically linked to the stress response, namely serotonin transporter (slc6a4), brain-derived neurotrophic factor (bdnf), and arginine vasopressin receptor (avpr1b) genes are associated with prognosis in colorectal cancer patients. |
2013-04-19 |
2023-08-12 |
Not clear |
| Gyorgy Bagdy, Gabriella Juhasz, Xenia Gond. A new clinical evidence-based gene-environment interaction model of depression. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 14. issue 4. 2013-04-12. PMID:23269207. |
in the newmood cohort polymorphisms of the genes of the serotonin transporter, 5-ht1a, 5-ht1b and 5-ht2a and endocannabinoid cb1 receptors, tryptophan hydroxylase, creb1, bdnf and girk provide evidence for the involvement of these genes in the development of depression. |
2013-04-12 |
2023-08-12 |
human |
| Sian M J Hemmings, Lindi I Martin, Marisa Klopper, Lize van der Merwe, Lisa Aitken, Erika de Wit, Gillian F Black, Eileen G Hoal, Gerhard Walzl, Soraya Seeda. BDNF Val66Met and DRD2 Taq1A polymorphisms interact to influence PTSD symptom severity: a preliminary investigation in a South African population. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:23103549. |
we evaluated the role that selected variants in serotonin transporter (5-htt), dopamine receptor 2 (drd2) and brain-derived neurotrophic factor (bdnf) genes play in ptsd symptom severity in an at-risk population. |
2013-03-26 |
2023-08-12 |
Not clear |
| Reiji Yoshimura, Taro Kishi, Hikaru Hori, Atsuko Ikenouchi-Sugita, Wakako Umene-Nakano, Asuka Katsuki, Kenji Hayashi, Nakao Iwata, Jun Nakamur. No Association between the Response to the Addition of an Atypical Antipsychotic Drug to an SSRI or SNRI and the BDNF (Val66Met) Polymorphism in Refractory Major Depressive Disorder in Japanese Patients. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 10. issue 1. 2013-02-25. PMID:23429762. |
this study examined the association between the brain-derived neurotrophic factor (bdnf) (val66met) polymorphism and the response to the addition of an atypical antipsychotic drug to a selective serotonin reuptake inhibitor (ssri) or serotonin-norepinephrine reuptake inhibitor (snri) in treatment-refractory depression. |
2013-02-25 |
2023-08-12 |
Not clear |
| C Camerino, M Zayzafoon, M Rymaszewski, J Heiny, M Rios, P V Hauschk. Central depletion of brain-derived neurotrophic factor in mice results in high bone mass and metabolic phenotype. Endocrinology. vol 153. issue 11. 2013-01-17. PMID:23011922. |
we show that deletion of central bdnf expression in mice results in increased bone mass and white adipose tissue, with no significant changes in sympathetic signaling or peripheral serotonin, associated with hyperphagia, obesity, and leptin resistance. |
2013-01-17 |
2023-08-12 |
mouse |
| Daria Peleg-Raibstein, Edlira Luca, Christian Wolfru. Maternal high-fat diet in mice programs emotional behavior in adulthood. Behavioural brain research. vol 233. issue 2. 2012-12-10. PMID:22633920. |
in addition, brain-derived neurotrophic factor (bdnf) was significantly increased in the dorsal hippocampus, while gaba(a) alpha2 receptor subunit and 5-hydroxytryptamine 1a (5-ht1a) receptor showed increased levels in the ventral hippocampus. |
2012-12-10 |
2023-08-12 |
mouse |
| N V Selianina, Iu V Karakulov. [The effect of neurotrophic treatment on the activation of reparative processes in patients with acute traumatic brain injury]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 112. issue 5. 2012-12-10. PMID:22951781. |
the complex study of cognitive and emotional status, levels of serum serotonin and brain-derived neurotrophic factor (bdnf) were performed in 72 patients with acute traumatic brain injury, with a special focus on middle brain injuries (mbi), treated with cerebrolysin. |
2012-12-10 |
2023-08-12 |
Not clear |
| N V Selianina, Iu V Karakulov. [The effect of neurotrophic treatment on the activation of reparative processes in patients with acute traumatic brain injury]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 112. issue 5. 2012-12-10. PMID:22951781. |
after the treatment, there were the decrease in the severity of neurological symptoms and a significant positive dynamics on the fab scale as well as the increase in blood bdnf and serotonin levels. |
2012-12-10 |
2023-08-12 |
Not clear |
| Gregory Oxenkrug, Rebbie Ratne. N-acetylserotonin and aging-associated cognitive impairment and depression. Aging and disease. vol 3. issue 4. 2012-11-28. PMID:23185714. |
considering that nas (but not serotonin or melatonin) is a potent agonist to high-affinity bdnf tyrosine kinase (trkb) receptors, antidepressant and cognition-enhancing effect of nas might be mediated by activation of trkb receptors. |
2012-11-28 |
2023-08-12 |
rat |
| Stacy S Drury, Mary M Gleason, Katherine P Theall, Anna T Smyke, Charles A Nelson, Nathan A Fox, Charles H Zeana. Genetic sensitivity to the caregiving context: the influence of 5httlpr and BDNF val66met on indiscriminate social behavior. Physiology & behavior. vol 106. issue 5. 2012-11-07. PMID:22133521. |
general linear mixed-effects models were used to examine the effect of the interaction between group status and functional polymorphisms in brain derived neurotrophic factor (bdnf) and the serotonin transporter (5htt) on levels of indiscriminate behavior over time. |
2012-11-07 |
2023-08-12 |
Not clear |
| Hyemee Park, Doyoung Yoo, Sunoh Kwon, Tae-Won Yoo, Hi-Joon Park, Dae-Hyun Hahm, Hyejung Lee, Seung-Tae Ki. Acupuncture stimulation at HT7 alleviates depression-induced behavioral changes via regulation of the serotonin system in the prefrontal cortex of maternally-separated rat pups. The journal of physiological sciences : JPS. vol 62. issue 4. 2012-10-29. PMID:22627707. |
tissue levels of serotonin (5-ht) and 5-hydroxyindole-3-acetic acid (5-hiaa) were then measured by high-performance liquid chromatography and expression of serotonin transporter (5-htt) and brain-derived neurotrophic factor (bdnf) were assessed by western blotting. |
2012-10-29 |
2023-08-12 |
rat |
| Haytham M Hashim, Nagy Fawzy, Mohab M Fawzi, Rehab A Kara. Brain-derived neurotrophic factor Val66Met polymorphism and obsessive-compulsive symptoms in Egyptian schizophrenia patients. Journal of psychiatric research. vol 46. issue 6. 2012-10-17. PMID:22521161. |
bdnf promote the function and growth of 5-ht neurons in the brain and modulate the synaptic plasticity of drd3-secreting neurons in the striatum, suggesting involvement of bdnf in the mediation of obsessive-compulsive disorder. |
2012-10-17 |
2023-08-12 |
Not clear |
| Hyo Youl Moon, Se Hyun Kim, Yong Ryoul Yang, Parkyong Song, Hyun Sook Yu, Hong Geun Park, Onyou Hwang, Whaseon Lee-Kwon, Jeong Kon Seo, Daehee Hwang, Jang Hyun Choi, Richard Bucala, Sung Ho Ryu, Yong Sik Kim, Pann-Ghill Su. Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 32. 2012-10-15. PMID:22826223. |
moreover, the mif receptor cd74 and the erk1/2 pathway mediate the mif-induced tph2 and bdnf gene expression as well as serotonin content. |
2012-10-15 |
2023-08-12 |
mouse |
| Jae-Min Kim, Robert Stewart, Kyung-Yeol Bae, Sung-Wan Kim, Hee-Ju Kang, Il-Seon Shin, Joon-Tae Kim, Man-Seok Park, Myung-Kyu Kim, Sung-Woo Park, Young-Hoon Kim, Jong-Keun Kim, Ki-Hyun Cho, Jin-Sang Yoo. Serotonergic and BDNF genes and risk of depression after stroke. Journal of affective disorders. vol 136. issue 3. 2012-10-09. PMID:22014446. |
polymorphisms of serotonin transporter (5-htt) and brain-derived neurotrophic factor (bdnf) have been investigated as candidate genes for post-stroke depression (psd). |
2012-10-09 |
2023-08-12 |
Not clear |
| S Kotsopoulo. [The neurobiology of autism]. Psychiatrike = Psychiatriki. vol 18. issue 3. 2012-10-02. PMID:22466627. |
neurotrophic factors which determine the developmental steps of the brain are examined such as serotonin, brain-derived neurotrophic factor (bdnf), the neuropeptide reelin, neuroligines and others. |
2012-10-02 |
2023-08-12 |
human |
| Prodip K Bose, Jiamei Hou, Ronald Parmer, Paul J Reier, Floyd J Thompso. Altered patterns of reflex excitability, balance, and locomotion following spinal cord injury and locomotor training. Frontiers in physiology. vol 3. 2012-10-02. PMID:22934014. |
these improvements were accompanied by marked upregulation of bdnf, gaba/gaba(b), and monoamines (e.g., norepinephrine and serotonin) which might account for these improved functions. |
2012-10-02 |
2023-08-12 |
human |
| Gabriele Baj, Valentina D'Alessandro, Laura Musazzi, Alessandra Mallei, Cesar R Sartori, Marina Sciancalepore, Daniela Tardito, Francesco Langone, Maurizio Popoli, Enrico Tongiorg. Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22318196. |
in cultured hippocampal neurons, application of serotonin or norepinephrine (10-50 μm) induced increase in synaptic transmission and targeting of bdnf mrna in dendrites. |
2012-09-21 |
2023-08-12 |
Not clear |