| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carrie Yochum, Shannon Doherty-Lyon, Carol Hoffman, Muhammad M Hossain, Judith T Zelikoff, Jason R Richardso. Prenatal cigarette smoke exposure causes hyperactivity and aggressive behavior: role of altered catecholamines and BDNF. Experimental neurology. vol 254. 2014-05-19. PMID:24486851. |
these behavioral abnormalities were accompanied by a significant decrease in striatal and cortical dopamine and serotonin and a significant reduction in brain-derived neurotrophic factor (bdnf) mrna and protein. |
2014-05-19 |
2023-08-12 |
mouse |
| Erika Comasco, Cecilia Åslund, Lars Oreland, Kent W Nilsso. Three-way interaction effect of 5-HTTLPR, BDNF Val66Met, and childhood adversity on depression: a replication study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 10. 2014-04-24. PMID:23481907. |
both the serotonin transporter linked promoter region (5-httlpr) and the brain-derived neurotrophic factor (bdnf) val66met polymorphisms have been shown to interact with unfavourable environment in relation to depression symptoms and to depression diagnosis. |
2014-04-24 |
2023-08-12 |
Not clear |
| Ling-ling Lu, Xiao-Heng Shen, Jing-xian Che. [Xuefu zhuyu oral liquid intervened stress-stimulated depression model rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 33. issue 5. 2014-04-18. PMID:23905383. |
to observe effects of xuefu zhuyu oral liquid (xzol) on the brain behavior and monoamine neurotransmitter 5-ht, and brain derived neurotrophic factor (bdnf) content on depression model rats. |
2014-04-18 |
2023-08-12 |
rat |
| Undurti N Da. Autism as a disorder of deficiency of brain-derived neurotrophic factor and altered metabolism of polyunsaturated fatty acids. Nutrition (Burbank, Los Angeles County, Calif.). vol 29. issue 10. 2014-04-14. PMID:23911220. |
autism has a strong genetic and environmental basis in which inflammatory markers and factors concerned with synapse formation, nerve transmission, and information processing such as brain-derived neurotrophic factor (bdnf), polyunsaturated fatty acids (pufas): arachidonic (aa), eicosapentaenoic (epa), and docosahexaenoic acids (dha) and their products and neurotransmitters: dopamine, serotonin, acetylcholine, γ-aminobutyric acid, and catecholamines and cytokines are altered. |
2014-04-14 |
2023-08-12 |
Not clear |
| Michal Taler, Oded Miron, Irit Gil-Ad, Abraham Weizma. Neuroprotective and procognitive effects of sertraline: in vitro and in vivo studies. Neuroscience letters. vol 550. 2014-04-11. PMID:23827216. |
selective serotonin reuptake inhibitors (ssris) stimulate synaptic plasticity and neurogenesis, most likely via the map-kinase signal transduction pathway (by phosphorilation of erk) and by stimulating neurotrophic factors such as brain derived neurotrophic factor (bdnf) and the neuroprotective protein (bcl-2). |
2014-04-11 |
2023-08-12 |
mouse |
| Arlette F Buchmann, Rainer Hellweg, Marcella Rietschel, Jens Treutlein, Stephanie H Witt, Ulrich S Zimmermann, Martin H Schmidt, Günter Esser, Tobias Banaschewski, Manfred Laucht, Michael Deuschl. BDNF Val 66 Met and 5-HTTLPR genotype moderate the impact of early psychosocial adversity on plasma brain-derived neurotrophic factor and depressive symptoms: a prospective study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 8. 2014-03-13. PMID:23058261. |
the aim of the present study was to examine the interplay of the bdnf val⁶⁶met and the serotonin transporter promoter (5-httlpr) polymorphisms in moderating the impact of early-life adversity on bdnf plasma concentration and depressive symptoms. |
2014-03-13 |
2023-08-12 |
human |
| Reiji Yoshimura, Taro Kishi, Hikaru Hori, Asuka Katsuki, Atsuko Sugita-Ikenouchi, Wakako Umene-Nakano, Kiyokazu Atake, Nakao Iwata, Jun Nakamur. Serum Levels of Brain-Derived Neurotrophic Factor at 4 Weeks and Response to Treatment with SSRIs. Psychiatry investigation. vol 11. issue 1. 2014-03-07. PMID:24605128. |
therefore, we hypothesized that the changes in serum levels of bdnf from baseline (t0) to 4 weeks (t4) after treatment with selective serotonin reuptake inhibitors (ssris) predict the response to the treatment at 8 weeks (t8) in depressed patients. |
2014-03-07 |
2023-08-12 |
Not clear |
| Elizabeth P Hayden, Thomas M Olino, Sara J Bufferd, Anna Miller, Lea R Dougherty, Haroon I Sheikh, Shiva M Singh, Daniel N Klei. The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: associations with cognitive vulnerability to depression in childhood. Development and psychopathology. vol 25. issue 3. 2014-03-06. PMID:23880378. |
preliminary work indicates that cognitive vulnerability to depression may be associated with variants of the serotonin transporter promoter polymorphism (5-httlpr) and the valine to methionine at position 66 (val66met) polymorphism of the brain-derived neurotrophic factor (bdnf) gene; however, existing reports come from small samples. |
2014-03-06 |
2023-08-12 |
Not clear |
| Francesca Calabrese, Gianluigi Guidotti, Anthonieke Middelman, Giorgio Racagni, Judith Homberg, Marco A Riv. Lack of serotonin transporter alters BDNF expression in the rat brain during early postnatal development. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23564488. |
lack of serotonin transporter alters bdnf expression in the rat brain during early postnatal development. |
2014-02-12 |
2023-08-12 |
rat |
| Richard Musil, Peter Zill, Florian Seemüller, Brigitta Bondy, Sebastian Meyer, Ilja Spellmann, Wolfram Bender, Mazda Adli, Isabella Heuser, Robert Fisher, Wolfgang Gaebel, Wolfgang Maier, Marcella Rietschel, Dan Rujescu, Rebecca Schennach, Hans-Jürgen Möller, Michael Riede. Genetics of emergent suicidality during antidepressive treatment--data from a naturalistic study on a large sample of inpatients with a major depressive episode. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 7. 2014-01-23. PMID:23063133. |
common polymorphisms involved in the tryptophan hydroxylase 1 (tph1) and 2 (tph2), serotonin transporter, monoamine oxidase a (maoa) and brain-derived neurotrophic factor (bdnf) were investigated in a naturalistic inpatient study of the german research network on depression. |
2014-01-23 |
2023-08-12 |
Not clear |
| T L Huan. Effects of antipsychotics on the BDNF in schizophrenia. Current medicinal chemistry. vol 20. issue 3. 2014-01-17. PMID:23157625. |
bdnf is also believed to interact with other neurotransmitter systems implicated in schizophrenia, such as dopamine, glutamate, serotonin and gaba. |
2014-01-17 |
2023-08-12 |
Not clear |
| Fuencisla Pilar-Cuéllar, Rebeca Vidal, Alvaro Díaz, Elena Castro, Severiano dos Anjos, Jesús Pascual-Brazo, Raquel Linge, Veronica Vargas, Helena Blanco, Beatriz Martínez-Villayandre, Ángel Pazos, Elsa M Valdizá. Neural plasticity and proliferation in the generation of antidepressant effects: hippocampal implication. Neural plasticity. vol 2013. 2013-12-30. PMID:23862076. |
we will especially focus on the hippocampal cellularity and plasticity modulation by serotonin, trophic factors as brain-derived neurotrophic factor (bdnf), and vascular endothelial growth factor (vegf) through intracellular signalling pathways-camp, wnt/ β -catenin, and mtor. |
2013-12-30 |
2023-08-12 |
Not clear |
| G Quesseveur, D J David, M C Gaillard, P Pla, M V Wu, H T Nguyen, V Nicolas, G Auregan, I David, A Dranovsky, P Hantraye, R Hen, A M Gardier, N Déglon, B P Guiar. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational psychiatry. vol 3. 2013-12-23. PMID:23632457. |
at nerve terminal such as the hippocampus, the enhancement of 5-ht availability increases brain-derived neurotrophic factor (bdnf) synthesis and signaling, a major event in the stimulation of adult neurogenesis. |
2013-12-23 |
2023-08-12 |
mouse |
| G Quesseveur, D J David, M C Gaillard, P Pla, M V Wu, H T Nguyen, V Nicolas, G Auregan, I David, A Dranovsky, P Hantraye, R Hen, A M Gardier, N Déglon, B P Guiar. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational psychiatry. vol 3. 2013-12-23. PMID:23632457. |
moreover, overexpressing bdnf revealed the anxiolytic-like activity of fluoxetine in the elevated plus maze while attenuating 5-ht neurotransmission in response to a blunted downregulation of the 5-ht1a autoreceptor. |
2013-12-23 |
2023-08-12 |
mouse |
| Li-Tao Yi, Jing Li, Qing Liu, Di Geng, Ya-Fei Zhou, Xiao-Qing Ke, Huan Chen, Lian-Jin Wen. Antidepressant-like effect of oleanolic acid in mice exposed to the repeated forced swimming test. Journal of psychopharmacology (Oxford, England). vol 27. issue 5. 2013-11-26. PMID:23151611. |
taken together, these findings imply that functions of 5-ht, ne and bdnf may be involved in the antidepressant-like effect of oleanolic acid. |
2013-11-26 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
we examined the effect of mild handling stress on 5-ht(1a) receptor function, as measured by 8-oh-dpat stimulated [(35)s]gtpγs binding, in bdnf(+/-) mice and mice with a forebrain-specific reduction in bdnf (embryonic bdnf inducible knockout mice). |
2013-10-31 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
other 5-ht(1a) receptor populations, specifically in frontal cortex and dorsal raphe, were resistant to the combined detrimental effects of mild stress and reductions in bdnf expression. |
2013-10-31 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
decreases in hippocampal 5-ht(1a) receptor function induced by mild stress in bdnf-deficient mice were prevented by administration of the selective serotonin reuptake inhibitor fluoxetine, which increased activation of trkb, the high affinity receptor for bdnf, in wild-type and bdnf(+/-) mice. |
2013-10-31 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
in hippocampal cultures, bdnf increased the capacity of 5-ht(1a) receptors to activate g proteins, an effect eliminated by the knockout of trkb, confirming trkb activation increases 5-ht(1a) receptor function. |
2013-10-31 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
the mechanisms underlying the sensitivity of hippocampal 5-ht(1a) receptors to mild stress and decreased bdnf expression remain to be elucidated and may have important implications for the emotional and cognitive impairments associated with stress-related mental illness. |
2013-10-31 |
2023-08-12 |
mouse |