All Relations between bdnf and serotonin

Publication Sentence Publish Date Extraction Date Species
Yingcong Yu, Shujuan Wu, Jianxin Li, Renye Wang, Xupei Xie, Xuefeng Yu, Jianchun Pan, Ying Xu, Liang Zhen. The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling. Metabolic brain disease. vol 30. issue 1. 2016-03-17. PMID:24807589. 5-ht(1a) receptor antagonist nan-190 reversed the effects of curcumin on behaviors and the changes of intestine, pcreb and bdnf expression, which are related to ibs. 2016-03-17 2023-08-13 rat
Lingpeng Zhu, Tingting Wei, Jing Gao, Xiayun Chang, He He, Mingxing Miao, Tianhua Ya. Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice. Neuroscience letters. vol 606. 2016-03-01. PMID:26300543. levels of neurotransmitters like norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in the prefrontal cortex were detected by hplc-ms. further, brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b (trkb) and nuclear factor-κb (nf-κb) in hippocampal was determined by western blot analysis. 2016-03-01 2023-08-13 mouse
Plinio C Casarotto, Paula C dos Santos, Guilherme A Lucas, Caroline Biojone, Roger L H Pobbe, Heloisa H Vilela-Costa, Samia R L Joca, Francisco S Guimarães, Hélio Zangross. BDNF-TRKB signaling system of the dorsal periaqueductal gray matter is implicated in the panicolytic-like effect of antidepressant drugs. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 6. 2016-02-16. PMID:25840741. only longterm treatment with the selective serotonin reuptake inhibitor fluoxetine was able to increase bdnf levels in this structure. 2016-02-16 2023-08-13 rat
Kerri S Rawson, David Dixon, Petra Nowotny, William M Ricci, Ellen F Binder, Thomas L Rodebaugh, Leah Wendleton, Peter Doré, Eric J Lenz. Association of functional polymorphisms from brain-derived neurotrophic factor and serotonin-related genes with depressive symptoms after a medical stressor in older adults. PloS one. vol 10. issue 3. 2016-02-04. PMID:25781924. we examined the valine (val) to methionine (met) polymorphism in brain-derived neurotrophic factor (bdnf), serotonin 1a receptor (5ht1a-rs6295) polymorphism, and the serotonin transporter-linked polymorphic region (5httlpr) interaction with the rs25531 a to g single nucleotide polymorphism (5httlpr-rs25531) as predictors of depressive symptoms. 2016-02-04 2023-08-13 human
N Singewald, C Schmuckermair, N Whittle, A Holmes, K J Ressle. Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacology & therapeutics. vol 149. 2015-12-15. PMID:25550231. the purpose of this review is to outline the literature showing how pharmacological interventions targeting neurotransmitter systems including serotonin, dopamine, noradrenaline, histamine, glutamate, gaba, cannabinoids, neuropeptides (oxytocin, neuropeptides y and s, opioids) and other targets (neurotrophins bdnf and fgf2, glucocorticoids, l-type-calcium channels, epigenetic modifications) as well as their downstream signaling pathways, can augment fear extinction and strengthen extinction memory persistently in preclinical models. 2015-12-15 2023-08-13 Not clear
Kent W Nilsson, Erika Comasco, Sheilagh Hodgins, Lars Oreland, Cecilia Åslun. Genotypes do not confer risk for delinquency but rather alter susceptibility to positive and negative environmental factors: gene-environmentinteractions of BDNF Val66Met, 5-HTTLPR, and MAOA-uVNTR [corrected]. The international journal of neuropsychopharmacology. vol 18. issue 5. 2015-12-08. PMID:25522433. the present study investigated interactions between the brain-derived neurotrophic factor gene (bdnf val66met), the serotonin transporter gene-linked polymorphic region (5-httlpr), the monoamine oxidase a (maoa-uvntr) polymorphisms, family conflict, sexual abuse, the quality of the child-parent relationship, and teenage delinquency. 2015-12-08 2023-08-13 Not clear
Christoph Kraus, Pia Baldinger, Christina Rami-Mark, Gregor Gryglewski, Gregor Gryglewsky, Georg S Kranz, Daniela Haeusler, Andreas Hahn, Wolfgang Wadsak, Markus Mitterhauser, Dan Rujescu, Siegfried Kasper, Rupert Lanzenberge. Exploring the impact of BDNF Val66Met genotype on serotonin transporter and serotonin-1A receptor binding. PloS one. vol 9. issue 9. 2015-12-07. PMID:25188405. exploring the impact of bdnf val66met genotype on serotonin transporter and serotonin-1a receptor binding. 2015-12-07 2023-08-13 Not clear
Christoph Kraus, Pia Baldinger, Christina Rami-Mark, Gregor Gryglewski, Gregor Gryglewsky, Georg S Kranz, Daniela Haeusler, Andreas Hahn, Wolfgang Wadsak, Markus Mitterhauser, Dan Rujescu, Siegfried Kasper, Rupert Lanzenberge. Exploring the impact of BDNF Val66Met genotype on serotonin transporter and serotonin-1A receptor binding. PloS one. vol 9. issue 9. 2015-12-07. PMID:25188405. the brain-derived neurotrophic factor (bdnf) val66met polymorphism (rs6265) may impact on the in-vivo binding of important serotonergic structures such as the serotonin transporter (5-htt) and the serotonin-1a (5-ht1a) receptor. 2015-12-07 2023-08-13 Not clear
Sang Jun Lee, Jun-Hyung Baek, Young-Hoon Ki. Brain-derived Neurotrophic Factor Is Associated with Cognitive Impairment in Elderly Korean Individuals. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 13. issue 3. 2015-11-24. PMID:26598587. the present study measured serum bdnf levels to investigate the associations of the bdnf val66met and 5-hydroxytryptamine transporter linked promoter region (5-httlpr) polymorphisms with cognitive function in elderly korean individuals. 2015-11-24 2023-08-13 Not clear
F Nees, S H Witt, R Dinu-Biringer, A Lourdusamy, J Tzschoppe, S Vollstädt-Klein, S Millenet, C Bach, L Poustka, T Banaschewski, G J Barker, A L W Bokde, U Bromberg, C Büchel, P J Conrod, J Frank, V Frouin, J Gallinat, H Garavan, P Gowland, A Heinz, B Ittermann, K Mann, J-L Martinot, T Paus, Z Pausova, T W Robbins, M N Smolka, M Rietschel, G Schumann, H Flo. BDNF Val66Met and reward-related brain function in adolescents: role for early alcohol consumption. Alcohol (Fayetteville, N.Y.). vol 49. issue 2. 2015-11-20. PMID:25650137. the nonsynonymous single nucleotide polymorphism in the brain-derived neurotrophic factor (bdnf) gene (rs6265/val66met) modulates the central nervous system activity of neurotransmitters involved in reward processing such as serotonin, dopamine, and glutamate. 2015-11-20 2023-08-13 rat
Magdalene C Jawahar, Chris Murgatroyd, Emma L Harrison, Bernhard T Baun. Epigenetic alterations following early postnatal stress: a review on novel aetiological mechanisms of common psychiatric disorders. Clinical epigenetics. vol 7. 2015-11-20. PMID:26583053. however, epigenetic changes in other candidate genes such as brain-derived neurotrophic factor (bdnf) and serotonin transporter are also implicated in early life stress (els) and susceptibility to adult psychiatric disorders. 2015-11-20 2023-08-13 human
Toshizo Ishikawa, Seiko Yasuda, Seiji Minoda, Takae Ibuki, Kayoko Fukuhara, Yasutake Iwanaga, Toru Ariyoshi, Hironori Sasak. Neurotropin(®) ameliorates chronic pain via induction of brain-derived neurotrophic factor. Cellular and molecular neurobiology. vol 35. issue 2. 2015-11-17. PMID:25283187. changes in perk1/2 and pcreb (immunohistochemistry), 5-ht, and bdnf protein level (elisa) and bdnf mrna (rt-pcr) were measured in the anterior cingulate cortex (acc) and in the rostral ventromedial medulla (rvm) 14 days after injury. 2015-11-17 2023-08-13 rat
Maira J Maturana, Cláudia Pudell, Adriano D S Targa, Laís S Rodrigues, Ana Carolina D Noseda, Mariana H Fortes, Patrícia Dos Santos, Cláudio Da Cunha, Sílvio M Zanata, Anete C Ferraz, Marcelo M S Lim. REM sleep deprivation reverses neurochemical and other depressive-like alterations induced by olfactory bulbectomy. Molecular neurobiology. vol 51. issue 1. 2015-10-20. PMID:24826915. remsd triggered antidepressant mechanisms such as the increment of brain-derived neurotrophic factor (bdnf) levels, within the substantia nigra pars compacta (snpc), which were strongly correlated to the swimming time (r = 0.83; p < 0.0001) and hippocampal serotonin (5-ht) content (r = 0.66; p = 0.004). 2015-10-20 2023-08-13 rat
Maira J Maturana, Cláudia Pudell, Adriano D S Targa, Laís S Rodrigues, Ana Carolina D Noseda, Mariana H Fortes, Patrícia Dos Santos, Cláudio Da Cunha, Sílvio M Zanata, Anete C Ferraz, Marcelo M S Lim. REM sleep deprivation reverses neurochemical and other depressive-like alterations induced by olfactory bulbectomy. Molecular neurobiology. vol 51. issue 1. 2015-10-20. PMID:24826915. we suggested that the neurochemical complexity inflicted by the obx model, counteracted by remsd, is directly correlated to the nigral bdnf expression and hippocampal 5-ht levels. 2015-10-20 2023-08-13 rat
Indira Mendez-David, Laurent Tritschler, Zeina El Ali, Marie-Hélène Damiens, Marc Pallardy, Denis J David, Saadia Kerdine-Römer, Alain M Gardie. Nrf2-signaling and BDNF: A new target for the antidepressant-like activity of chronic fluoxetine treatment in a mouse model of anxiety/depression. Neuroscience letters. vol 597. 2015-10-19. PMID:25916883. taken together, these data suggest that nrf2 signaling contributes to fluoxetine-induced neuroprotection via an unexpected mechanism involving 5-ht transporter sert blockade, and not through enhancement of bdnf expression. 2015-10-19 2023-08-13 mouse
Q-S Wang, J-S Tian, Y-L Cui, S Ga. Genipin is active via modulating monoaminergic transmission and levels of brain-derived neurotrophic factor (BDNF) in rat model of depression. Neuroscience. vol 275. 2015-10-15. PMID:24972301. the mrna expressions of 5-hydroxytryptamine 1a receptor (5-ht1ar), camp response element binding protein (creb) and brain-derived neurotrophic factor (bdnf) in rats were decreased exposed to cums, which were reversed by genipin-treated rats exposed to cums. 2015-10-15 2023-08-13 rat
Q-S Wang, J-S Tian, Y-L Cui, S Ga. Genipin is active via modulating monoaminergic transmission and levels of brain-derived neurotrophic factor (BDNF) in rat model of depression. Neuroscience. vol 275. 2015-10-15. PMID:24972301. these results suggest that the possible mechanism of antidepressant-like effects on genipin, at least in one part, resulted from monoaminergic neurotransmitter system and the potential dysfunctional regulation of the post-receptor signaling pathway, which particularly affected the 5-ht(1a)r, 5-ht(2a)r and bdnf levels in the hippocampus. 2015-10-15 2023-08-13 rat
Z M Ignácio, G Z Réus, H M Abelaira, J Queved. Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: insights in depression. Neuroscience. vol 275. 2015-10-15. PMID:24972302. epidemiological studies have shown significant results in the interaction between the functions of brain-derived neurotrophic factor (bdnf) and 5-ht in mood disorders, such as major depressive disorder (mdd). 2015-10-15 2023-08-13 Not clear
Blanca Gutiérrez, Juan Á Bellón, Margarita Rivera, Esther Molina, Michael King, Louise Marston, Francisco Torres-González, Berta Moreno-Küstner, Patricia Moreno-Peral, Emma Motrico, Carmen Montón-Franco, María J GildeGómez-Barragán, Marta Sánchez-Celaya, Miguel Á Díaz-Barreiros, Catalina Vicens, Juan de Dios Luna, Irwin Nazareth, Jorge Cervill. The risk for major depression conferred by childhood maltreatment is multiplied by BDNF and SERT genetic vulnerability: a replication study. Journal of psychiatry & neuroscience : JPN. vol 40. issue 3. 2015-10-15. PMID:25510949. there is limited evidence for a moderating role of both serotonin transporter (sert) and brain-derived neurotrophic factor (bdnf) genes on the risk for major depression (md) developing after childhood maltreatment. 2015-10-15 2023-08-13 Not clear
Jennifer D Cooke, Hannah M Cavender, Hope K Lima, Lawrence M Grove. Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus. Psychopharmacology. vol 231. issue 23. 2015-10-07. PMID:24781518. previously, we found that treatment with venlafaxine, a serotonin and norepinephrine reuptake inhibitor (snri), but not citalopram, a selective serotonin reuptake inhibitor (ssri), reduced ltp in hippocampal area ca1 without changing hippocampal bdnf protein expression. 2015-10-07 2023-08-13 Not clear