| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z M Ignácio, G Z Réus, H M Abelaira, J Queved. Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: insights in depression. Neuroscience. vol 275. 2015-10-15. PMID:24972302. |
epidemiological studies have shown significant results in the interaction between the functions of brain-derived neurotrophic factor (bdnf) and 5-ht in mood disorders, such as major depressive disorder (mdd). |
2015-10-15 |
2023-08-13 |
Not clear |
| Blanca Gutiérrez, Juan Á Bellón, Margarita Rivera, Esther Molina, Michael King, Louise Marston, Francisco Torres-González, Berta Moreno-Küstner, Patricia Moreno-Peral, Emma Motrico, Carmen Montón-Franco, María J GildeGómez-Barragán, Marta Sánchez-Celaya, Miguel Á Díaz-Barreiros, Catalina Vicens, Juan de Dios Luna, Irwin Nazareth, Jorge Cervill. The risk for major depression conferred by childhood maltreatment is multiplied by BDNF and SERT genetic vulnerability: a replication study. Journal of psychiatry & neuroscience : JPN. vol 40. issue 3. 2015-10-15. PMID:25510949. |
there is limited evidence for a moderating role of both serotonin transporter (sert) and brain-derived neurotrophic factor (bdnf) genes on the risk for major depression (md) developing after childhood maltreatment. |
2015-10-15 |
2023-08-13 |
Not clear |
| Jennifer D Cooke, Hannah M Cavender, Hope K Lima, Lawrence M Grove. Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus. Psychopharmacology. vol 231. issue 23. 2015-10-07. PMID:24781518. |
previously, we found that treatment with venlafaxine, a serotonin and norepinephrine reuptake inhibitor (snri), but not citalopram, a selective serotonin reuptake inhibitor (ssri), reduced ltp in hippocampal area ca1 without changing hippocampal bdnf protein expression. |
2015-10-07 |
2023-08-13 |
Not clear |
| Ileana P Marinescu, Maria Camelia Foarfă, Mihail Cristian Pîrlog, Adriana Turculean. Prenatal depression and stress - risk factors for placental pathology and spontaneous abortion. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 55. issue 3 Suppl. 2015-09-21. PMID:25607399. |
markers of genetic vulnerability are catechol-o-methyltransferase, monoamine oxidase-a, variation of serotonin transporters, low levels of dopamine-beta-hydroxylase, and brain derived neurotrophic factor val66met (bdnf), while hyperactivity of hpa (hypothalamic-pituitary-adrenal) axis and massive release of endogenous cortisol, regulated by metalloproteinase-1, -2, -3 and -9, and are involved both in depressive symptoms and neurodevelopmental abnormalities in fetus. |
2015-09-21 |
2023-08-13 |
Not clear |
| Sawsan Aboul-Fotou. Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters. Psychopharmacology. vol 232. issue 6. 2015-09-02. PMID:25315361. |
additionally, mec modulated the prefrontal cortex (pfc) level of brain-derived neurotrophic factor (bdnf), 5-hydroxy tryptamine (5-ht), and norepinephrine (ne). |
2015-09-02 |
2023-08-13 |
rat |
| Tae-Woon Kim, Baek-Vin Lim, Kijeong Kim, Jin-Hee Seo, Chang-Ju Ki. Treadmill exercise alleviates stress-induced impairment of social interaction through 5-hydroxytryptamine 1A receptor activation in rats. Journal of exercise rehabilitation. vol 11. issue 4. 2015-09-02. PMID:26331133. |
we in-vestigated the effect of treadmill exercise on social interaction in relation with bdnf and 5-ht expressions following stress in rats. |
2015-09-02 |
2023-08-13 |
rat |
| Michael J Weiser, Kelly Wynalda, Norman Salem, Christopher M But. Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats. Journal of lipid research. vol 56. issue 1. 2015-09-01. PMID:25411442. |
we sought to address these questions by 1) feeding pregnant rats with diets sufficient or deficient in dha during gestation and lactation; 2) weaning their male offspring to diets that were sufficient or deficient in dha; and 3) assessing depression-related behaviors (forced swim test), plasma biomarkers [brain-derived neurotrophic factor (bdnf), serotonin, and melatonin], and brain biomarkers (bdnf) in the offspring before and after puberty. |
2015-09-01 |
2023-08-13 |
rat |
| Dafu Yu, Heng Zhou, Yuan Yang, Yong Jiang, Tianchao Wang, Liang Lv, Qixin Zhou, Yuexiong Yang, Xuexian Dong, Jianfeng He, Xiaoyan Huang, Jijun Chen, Kunhua Wu, Lin Xu, Rongrong Ma. The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats. Hormones and behavior. vol 69. 2015-08-24. PMID:25623236. |
diminished levels of brain serotonin (5-ht) and increased levels of hippocampal brain-derived neurotrophic factor (bdnf) were found in the hypothyroid rats compared to the control saline-vehicle administered rats. |
2015-08-24 |
2023-08-13 |
rat |
| Dafu Yu, Heng Zhou, Yuan Yang, Yong Jiang, Tianchao Wang, Liang Lv, Qixin Zhou, Yuexiong Yang, Xuexian Dong, Jianfeng He, Xiaoyan Huang, Jijun Chen, Kunhua Wu, Lin Xu, Rongrong Ma. The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats. Hormones and behavior. vol 69. 2015-08-24. PMID:25623236. |
the hyperthyroid rats exhibited higher anxiety- and depression-like behaviors, higher brain 5-ht level, and lower hippocampal bdnf levels than the controls. |
2015-08-24 |
2023-08-13 |
rat |
| Patrick M Fisher, Klaus K Holst, Dea Adamsen, Anders Bue Klein, Vibe G Frokjaer, Peter S Jensen, Claus Svarer, Nic Gillings, William F C Baare, Jens D Mikkelsen, Gitte M Knudse. BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Human brain mapping. vol 36. issue 1. 2015-08-19. PMID:25220079. |
bdnf val66met and 5-httlpr polymorphisms predict a human in vivo marker for brain serotonin levels. |
2015-08-19 |
2023-08-13 |
human |
| Patrick M Fisher, Klaus K Holst, Dea Adamsen, Anders Bue Klein, Vibe G Frokjaer, Peter S Jensen, Claus Svarer, Nic Gillings, William F C Baare, Jens D Mikkelsen, Gitte M Knudse. BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Human brain mapping. vol 36. issue 1. 2015-08-19. PMID:25220079. |
brain-derived neurotrophic factor (bdnf) has been implicated in multiple aspects of brain function including regulation of serotonin signaling. |
2015-08-19 |
2023-08-13 |
human |
| Patrick M Fisher, Klaus K Holst, Dea Adamsen, Anders Bue Klein, Vibe G Frokjaer, Peter S Jensen, Claus Svarer, Nic Gillings, William F C Baare, Jens D Mikkelsen, Gitte M Knudse. BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Human brain mapping. vol 36. issue 1. 2015-08-19. PMID:25220079. |
the bdnf val66met polymorphism (rs6265) has been linked to aspects of serotonin signaling in humans but its effects are not well understood. |
2015-08-19 |
2023-08-13 |
human |
| Patrick M Fisher, Klaus K Holst, Dea Adamsen, Anders Bue Klein, Vibe G Frokjaer, Peter S Jensen, Claus Svarer, Nic Gillings, William F C Baare, Jens D Mikkelsen, Gitte M Knudse. BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Human brain mapping. vol 36. issue 1. 2015-08-19. PMID:25220079. |
to address this, we evaluated whether bdnf val66met was predictive of a putative marker of brain serotonin levels, serotonin 4 receptor (5-ht4 ) binding assessed with [11c]sb207145 positron emission tomography, which has also been associated with the serotonin-transporter-linked polymorphic region (5-httlpr) polymorphism. |
2015-08-19 |
2023-08-13 |
human |
| Patrick M Fisher, Klaus K Holst, Dea Adamsen, Anders Bue Klein, Vibe G Frokjaer, Peter S Jensen, Claus Svarer, Nic Gillings, William F C Baare, Jens D Mikkelsen, Gitte M Knudse. BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Human brain mapping. vol 36. issue 1. 2015-08-19. PMID:25220079. |
our findings indicate that bdnf val66met significantly predicts a common regulator of brain [11c]sb207145 binding, which we hypothesize reflects brain serotonin levels. |
2015-08-19 |
2023-08-13 |
human |
| Patrick M Fisher, Klaus K Holst, Dea Adamsen, Anders Bue Klein, Vibe G Frokjaer, Peter S Jensen, Claus Svarer, Nic Gillings, William F C Baare, Jens D Mikkelsen, Gitte M Knudse. BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Human brain mapping. vol 36. issue 1. 2015-08-19. PMID:25220079. |
these findings implicate serotonin signaling as an important molecular mediator underlying the effects of bdnf val66met and 5-httlpr on behavior and related risk for neuropsychiatric illness in humans. |
2015-08-19 |
2023-08-13 |
human |
| Dante Cicchetti, Fred A Rogosc. Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children. Development and psychopathology. vol 26. issue 4 Pt 2. 2015-08-03. PMID:25422957. |
genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-httlpr), brain-derived neurotrophic factor (bdnf), norepinephrine transporter (net), and corticotropin releasing hormone receptor 1 (crhr1) genes in african american children. |
2015-08-03 |
2023-08-13 |
Not clear |
| Dante Cicchetti, Fred A Rogosc. Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children. Development and psychopathology. vol 26. issue 4 Pt 2. 2015-08-03. PMID:25422957. |
dna was obtained from buccal cell or saliva samples and genotyped for polymorphisms of the following genes: serotonin transporter linked polymorphic region (5-httlpr), brain-derived neurotrophic factor (bdnf), norepinephrine transporter, and corticotropin releasing hormone receptor 1. |
2015-08-03 |
2023-08-13 |
Not clear |
| Qi-Xiang Song, Christopher J Chermansky, Lori A Birder, Longkun Li, Margot S Damase. Brain-derived neurotrophic factor in urinary continence and incontinence. Nature reviews. Urology. vol 11. issue 10. 2015-07-15. PMID:25224451. |
serotonin and noradrenaline reuptake inhibitors, used to treat both depression and sui, result in enhanced bdnf levels. |
2015-07-15 |
2023-08-13 |
Not clear |
| Saborni Roy, Hanuman Prasad Sharma, Tapas C Nag, Thirumurthy Velpandian, Ashish Datt Upadhyay, Rashmi Mathur, Suman Jai. BDNF mediated activity dependent maturation of visual Wulst following prenatal repetitive auditory stimulation at a critical developmental period in domestic chicks (Gallus domesticus). Brain research bulletin. vol 109. 2015-07-10. PMID:25305344. |
concomitant with this, there was a significant increase in the expression of bdnf and levels of neurotransmitters gaba, glutamate, norepinephrine and serotonin from e18 only in both hemispheres of the visual wulst. |
2015-07-10 |
2023-08-13 |
Not clear |
| Sandra M W van de Wiel, Michel M Verheij, Judith R Homber. Designing modulators of 5-hydroxytryptamine signaling to treat abuse disorders. Expert opinion on drug discovery. vol 9. issue 11. 2015-06-22. PMID:25217125. |
brain-derived neurotropic factor (bdnf) is an important modulator of the serotonergic system and 5-ht modulates bdnf expression. |
2015-06-22 |
2023-08-13 |
Not clear |