| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei-Chi Li, Hsiang-Tai Chao, Ming-Wei Lin, Horng-Der Shen, Li-Fen Chen, Jen-Chuen Hsie. Neuroprotective effect of Val variant of BDNF Val66Met polymorphism on hippocampus is modulated by the severity of menstrual pain. NeuroImage. Clinical. vol 30. 2021-07-30. PMID:33561695. |
significant interactions between pdm severity and bdnf val66met genotype were observed in the right whole hippocampus, subiculum, and molecular layer. |
2021-07-30 |
2023-08-13 |
human |
| Wei-Chi Li, Hsiang-Tai Chao, Ming-Wei Lin, Horng-Der Shen, Li-Fen Chen, Jen-Chuen Hsie. Neuroprotective effect of Val variant of BDNF Val66Met polymorphism on hippocampus is modulated by the severity of menstrual pain. NeuroImage. Clinical. vol 30. 2021-07-30. PMID:33561695. |
when confronted with years of repeated pdm stress, the hippocampus can undergo differential structural changes in accordance with the bdnf genotype and pain severity. |
2021-07-30 |
2023-08-13 |
human |
| Vlad Dionisie, Adela Magdalena Ciobanu, Vlad Alexandru Toma, Mihnea Costin Manea, Ioana Baldea, Diana Olteanu, Alexandra Sevastre-Berghian, Simona Clichici, Mirela Manea, Sorin Riga, Gabriela Adriana Fili. Escitalopram Targets Oxidative Stress, Caspase-3, BDNF and MeCP2 in the Hippocampus and Frontal Cortex of a Rat Model of Depression Induced by Chronic Unpredictable Mild Stress. International journal of molecular sciences. vol 22. issue 14. 2021-07-30. PMID:34299103. |
escitalopram targets oxidative stress, caspase-3, bdnf and mecp2 in the hippocampus and frontal cortex of a rat model of depression induced by chronic unpredictable mild stress. |
2021-07-30 |
2023-08-13 |
rat |
| Vlad Dionisie, Adela Magdalena Ciobanu, Vlad Alexandru Toma, Mihnea Costin Manea, Ioana Baldea, Diana Olteanu, Alexandra Sevastre-Berghian, Simona Clichici, Mirela Manea, Sorin Riga, Gabriela Adriana Fili. Escitalopram Targets Oxidative Stress, Caspase-3, BDNF and MeCP2 in the Hippocampus and Frontal Cortex of a Rat Model of Depression Induced by Chronic Unpredictable Mild Stress. International journal of molecular sciences. vol 22. issue 14. 2021-07-30. PMID:34299103. |
escitalopram had a modulatory effect on bdnf and the number of oligodendrocytes in the hippocampus and frontal lobe and also improved the mecp2 expressions. |
2021-07-30 |
2023-08-13 |
rat |
| Daymara Mercerón-Martínez, William Almaguer-Melian, Esteban Alberti-Amador, Rául Calderón-Peña, Jorge A Bergad. Amygdala stimulation ameliorates memory impairments and promotes c-Fos activity in fimbria-fornix-lesioned rats. Synapse (New York, N.Y.). vol 74. issue 12. 2021-07-27. PMID:32621298. |
the mechanisms for this improvement involve early gene expression and synthesis of bdnf, map-2, and gap43 in the hippocampus and prefrontal cortex. |
2021-07-27 |
2023-08-13 |
rat |
| Mary E Dail, Meghan L M Brino, Janice E Chamber. Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression. Journal of biochemical and molecular toxicology. vol 35. issue 6. 2021-07-27. PMID:33682265. |
the hippocampus was examined via quantitative polymerase chain reaction for the expression of immediate-early genes involved in brain repair (bdnf), increasing neurotoxicity (fos), and apoptosis control (jdp2, bcl2l1, bcl2l11). |
2021-07-27 |
2023-08-13 |
rat |
| Mary E Dail, Meghan L M Brino, Janice E Chamber. Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression. Journal of biochemical and molecular toxicology. vol 35. issue 6. 2021-07-27. PMID:33682265. |
in the hippocampus, nimp increased the expression of the neurotoxicity marker fos and decreased the expression of neuroprotective bdnf and antiapoptotic bcl2l1. |
2021-07-27 |
2023-08-13 |
rat |
| Marta Anna Lech, Monika Leśkiewicz, Kinga Kamińska, Zofia Rogóż, Elżbieta Lorenc-Koc. Glutathione Deficiency during Early Postnatal Development Causes Schizophrenia-Like Symptoms and a Reduction in BDNF Levels in the Cortex and Hippocampus of Adult Sprague-Dawley Rats. International journal of molecular sciences. vol 22. issue 12. 2021-07-26. PMID:34201038. |
glutathione deficiency during early postnatal development causes schizophrenia-like symptoms and a reduction in bdnf levels in the cortex and hippocampus of adult sprague-dawley rats. |
2021-07-26 |
2023-08-13 |
rat |
| Tatiana A Gudasheva, Anna V Tallerova, Armen G Mezhlumyan, Tatyana A Antipova, Ilya O Logvinov, Yulia N Firsova, Polina Y Povarnina, Sergey B Seredeni. Low-Molecular Weight BDNF Mimetic, Dimeric Dipeptide GSB-106, Reverses Depressive Symptoms in Mouse Chronic Social Defeat Stress. Biomolecules. vol 11. issue 2. 2021-07-23. PMID:33578683. |
thus, the present results demonstrate the dipeptide bdnf mimetic gsb-106 reversed depressive-like behavior and restored hippocampal neuroplasticity in a rodent depression model. |
2021-07-23 |
2023-08-13 |
mouse |
| Hien Luong, Sarojini Singh, Mallikarjun Patil, Prasanna Krishnamurth. Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice. American journal of physiology. Heart and circulatory physiology. vol 320. issue 5. 2021-07-23. PMID:33834865. |
mice in the cms group show a significant decrease in protein expression of hippocampal brain-derived neurotrophic factor (bdnf) and exhibit depression-like behavioral changes, such as learned helplessness and decreased exploration behavior, as compared with the control group. |
2021-07-23 |
2023-08-13 |
mouse |
| Xiao-Chen Yu, Zhen Li, Xin-Ran Liu, Jia-Ni Hu, Rui Liu, Na Zhu, Yong L. The Antioxidant Effects of Whey Protein Peptide on Learning and Memory Improvement in Aging Mice Models. Nutrients. vol 13. issue 6. 2021-07-23. PMID:34205338. |
its specific mechanism may be related to reducing the degeneration of hippocampal nerve cells, reducing the apoptosis of nerve cells, improving the activity of ache, reducing the expression of inflammatory factors (tnf-α and il-1β) in brain tissue, reducing oxidative stress injury, and improving the expression of p-camkⅡ and bdnf synaptic plasticity protein. |
2021-07-23 |
2023-08-13 |
mouse |
| Virendra Tiwari, Akanksha Mishra, Sonu Singh, Sandeep Kumar Mishra, Kiran Kumari Sahu, Parul, Mahesh J Kulkarni, Rakesh Shukla, Shubha Shukl. Protriptyline improves spatial memory and reduces oxidative damage by regulating NFκB-BDNF/CREB signaling axis in streptozotocin-induced rat model of Alzheimer's disease. Brain research. vol 1754. 2021-07-22. PMID:33422534. |
stz induced impairment in spatial learning and retention memory was associated with increased nfκb and reduced creb and bdnf expression in cortex and hippocampus. |
2021-07-22 |
2023-08-13 |
rat |
| Daniel A Paredes, Ahmad Jalloh, Briony J Catlow, Amritha Jaishankar, Seungmae Seo, Dennisse V Jimenez, Keri Martinowich, Marcelo Diaz-Bustamante, Daniel J Hoeppner, Ronald D G McKa. Bdnf deficiency in the neonatal hippocampus contributes to global dna hypomethylation and adult behavioral changes. Brain research. vol 1754. 2021-07-22. PMID:33422542. |
bdnf deficiency in the neonatal hippocampus contributes to global dna hypomethylation and adult behavioral changes. |
2021-07-22 |
2023-08-13 |
Not clear |
| Daniel A Paredes, Ahmad Jalloh, Briony J Catlow, Amritha Jaishankar, Seungmae Seo, Dennisse V Jimenez, Keri Martinowich, Marcelo Diaz-Bustamante, Daniel J Hoeppner, Ronald D G McKa. Bdnf deficiency in the neonatal hippocampus contributes to global dna hypomethylation and adult behavioral changes. Brain research. vol 1754. 2021-07-22. PMID:33422542. |
here we provide in vivo evidence that transient pharmacological inactivation of the hippocampus via tetrodotoxin microinjections or a genetic reduction in brain derived neurotrophic factor (bdnf) protein levels (bdnf |
2021-07-22 |
2023-08-13 |
Not clear |
| Chuan-An Yi, Yu-Hong Jiang, Ye Wang, Yu-Xian Li, Shi-Chang Cai, Xiu-Yu Wu, Xiang-Shang Hu, Xing-Guang Wa. Black Bamboo Rhizome Extract Improves Cognitive Dysfunction by Upregulating the Expression of Hippocampal BDNF and CREB in Rats with Cerebral Ischaemia-Reperfusion Injury. Neuropsychiatric disease and treatment. vol 17. 2021-07-22. PMID:34285486. |
black bamboo rhizome extract improves cognitive dysfunction by upregulating the expression of hippocampal bdnf and creb in rats with cerebral ischaemia-reperfusion injury. |
2021-07-22 |
2023-08-13 |
rat |
| Michael Zhang, Haley F Spencer, Rina Y Berman, Kennett D Radford, Kwang H Cho. Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats. IBRO neuroscience reports. vol 11. 2021-07-22. PMID:34286313. |
two hours after the infusion, brain tissue was dissected to obtain the medial prefrontal cortex (mpfc), hippocampus including the ca1, ca3, and dentate gyrus, and amygdala followed by western blot analyses of a transcription factor (c-fos), brain-derived neurotrophic factor (bdnf), and phosphorylated extracellular signal-regulated kinase (perk). |
2021-07-22 |
2023-08-13 |
rat |
| Michael Zhang, Haley F Spencer, Rina Y Berman, Kennett D Radford, Kwang H Cho. Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats. IBRO neuroscience reports. vol 11. 2021-07-22. PMID:34286313. |
in the hippocampus, 10 mg/kg ketamine reduced bdnf levels in male, but not female, rats. |
2021-07-22 |
2023-08-13 |
rat |
| Yoonju Kim, Youn-Jung Ki. Effect of Obesity on Cognitive Impairment in Vascular Dementia Rat Model via BDNF-ERK-CREB Pathway. Biological research for nursing. vol 23. issue 2. 2021-07-21. PMID:32844660. |
we also evaluated brain-derived neurotrophic factor (bdnf), phosphorylated extracellular signal-regulated kinase (perk), and phosphorylated cyclic adenosine monophosphate response element-binding protein (pcreb) in the hippocampus. |
2021-07-21 |
2023-08-13 |
rat |
| Mohadeseh Chahkandi, Gholamreza Komeili, Gholamreza Sepehri, Mohammad Khaksari, Sedigheh Amiresmail. Marijuana and β-estradiol interactions on spatial learning and memory in young female rats: Lack of role of the G protein-coupled estrogen receptor (GPR30). Life sciences. vol 280. 2021-07-20. PMID:34146552. |
we also assessed the bdnf (brain-derived neurotrophic factor) concentration and the hippocampal level of gpr30. |
2021-07-20 |
2023-08-13 |
rat |
| Myoung-Gwi Ryou, Xiaoan Chen, Ming Cai, Hong Wang, Marianna E Jung, Daniel B Metzger, Robert T Mallet, Xiangrong Sh. Intermittent Hypoxia Training Prevents Deficient Learning-Memory Behavior in Mice Modeling Alzheimer's Disease: A Pilot Study. Frontiers in aging neuroscience. vol 13. 2021-07-20. PMID:34276338. |
this study tested the hypothesis that iht improves learning-memory behavior, diminishes aβ accumulation in cerebral cortex and hippocampus, and enhances cerebrocortical contents of the neuroprotective trophic factors erythropoietin and brain-derived neurotrophic factor (bdnf) in mice manifesting ad traits. |
2021-07-20 |
2023-08-13 |
mouse |