| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roberta Passos Palazzo, Iraci L S Torres, Ágnis Iohana Grefenhagen, Bruno Batista da Silva, Louisiana Carolina Ferreira de Meireles, Kethleen Costa de Vargas, Zingara Alves, Lenir Orlandi Pereira Silva, Ionara Rodrigues Siqueir. Early life exposure to hypercaloric diet impairs eating behavior during weaning: The role of BDNF signaling and astrocyte marks. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 80. issue 7. 2021-08-26. PMID:32926590. |
hypercaloric diet exposure reduced bdnf levels in the olfactory bulb and hippocampus from rats of both sexes and increased the content of the trkb receptor in hippocampi. |
2021-08-26 |
2023-08-13 |
rat |
| Xingrao Ke, Yingliu Huang, Qi Fu, Robert H Lane, Amber Majni. Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus. Developmental neuroscience. vol 43. issue 2. 2021-08-25. PMID:33940573. |
epigenetic regulators, including micrornas, have been shown to affect cognitive function by altering hippocampal neurogenesis which is regulated in part by brain-derived neurotropic factor (bdnf). |
2021-08-25 |
2023-08-13 |
mouse |
| Xingrao Ke, Yingliu Huang, Qi Fu, Robert H Lane, Amber Majni. Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus. Developmental neuroscience. vol 43. issue 2. 2021-08-25. PMID:33940573. |
we sought to investigate the effects of ame on mir profile and their epigenetic characteristics, as well as neurogenesis and bdnf expression in mouse hippocampus. |
2021-08-25 |
2023-08-13 |
mouse |
| Xingrao Ke, Yingliu Huang, Qi Fu, Robert H Lane, Amber Majni. Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus. Developmental neuroscience. vol 43. issue 2. 2021-08-25. PMID:33940573. |
furthermore, ame significantly decreased hippocampal neurogenesis by decreasing cell numbers of ki67+ (proliferation marker), neurod1+ (neuronal differentiation marker), and neun+ (mature neuronal marker) in the dentate gyrus (dg) region concurrently with decreased hippocampal bdnf protein levels. |
2021-08-25 |
2023-08-13 |
mouse |
| Xingrao Ke, Yingliu Huang, Qi Fu, Robert H Lane, Amber Majni. Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus. Developmental neuroscience. vol 43. issue 2. 2021-08-25. PMID:33940573. |
we speculate that the changes in epigenetic profile at mir-10b promoter may contribute to upregulation of mir-10b-5p and subsequently lead to decreased bdnf levels in a model of impaired offspring hippocampal neurogenesis and cognition in mice. |
2021-08-25 |
2023-08-13 |
mouse |
| Narmin Farazi, Javad Mahmoudi, Saeed Sadigh-Eteghad, Fereshteh Farajdokht, Seyed Hossein Rast. Synergistic effects of combined therapy with transcranial photobiomodulation and enriched environment on depressive- and anxiety-like behaviors in a mice model of noise stress. Lasers in medical science. 2021-08-25. PMID:34432186. |
also, there is no available data on the relationship between the application of tpbm and hippocampal brain-derived neurotrophic factor (bdnf) expression in animal models of stress. |
2021-08-25 |
2023-08-13 |
mouse |
| Narmin Farazi, Javad Mahmoudi, Saeed Sadigh-Eteghad, Fereshteh Farajdokht, Seyed Hossein Rast. Synergistic effects of combined therapy with transcranial photobiomodulation and enriched environment on depressive- and anxiety-like behaviors in a mice model of noise stress. Lasers in medical science. 2021-08-25. PMID:34432186. |
bdnf, tyrosine receptor kinase b (trkb), and camp response element-binding (creb) protein levels in the hippocampus were determined by the western blot method, and also serum corticosterone levels were assessed using an elisa kit. |
2021-08-25 |
2023-08-13 |
mouse |
| Narmin Farazi, Javad Mahmoudi, Saeed Sadigh-Eteghad, Fereshteh Farajdokht, Seyed Hossein Rast. Synergistic effects of combined therapy with transcranial photobiomodulation and enriched environment on depressive- and anxiety-like behaviors in a mice model of noise stress. Lasers in medical science. 2021-08-25. PMID:34432186. |
exposure to noise stress significantly elevated serum corticosterone level; downregulated hippocampal bdnf, trkb, and creb protein expressions; and resulted in depressive- and anxiety-like behaviors. |
2021-08-25 |
2023-08-13 |
mouse |
| Kevin J Zhang, Rajan A Ramdev, Nicholas J Tuta, Mark D Spritze. Dose-dependent effects of testosterone on spatial learning strategies and brain-derived neurotrophic factor in male rats. Psychoneuroendocrinology. vol 121. 2021-08-24. PMID:32892065. |
furthermore, we quantified concentrations of brain-derived neurotrophic factor (pro-, mature-, and total bdnf) in the prefrontal cortex, hippocampus, and striatum. |
2021-08-24 |
2023-08-13 |
rat |
| Kevin J Zhang, Rajan A Ramdev, Nicholas J Tuta, Mark D Spritze. Dose-dependent effects of testosterone on spatial learning strategies and brain-derived neurotrophic factor in male rats. Psychoneuroendocrinology. vol 121. 2021-08-24. PMID:32892065. |
in addition, we found that a low dose of testosterone (0.125 mg) increased total bdnf in the striatum, while a high dose (0.500 mg) increased total bdnf in the hippocampus. |
2021-08-24 |
2023-08-13 |
rat |
| Roberto Farina Almeida, Yasmine Nonose, Marcelo Ganzella, Samanta Oliveira Loureiro, Andréia Rocha, Daniele Guilhermano Machado, Bruna Bellaver, Fernanda Urruth Fontella, Douglas T Leffa, Letícia Ferreira Pettenuzzo, Gianina Teribele Venturin, Samuel Greggio, Jaderson Costa da Costa, Eduardo R Zimmer, Elaine Elisabetsky, Diogo O Souz. Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model. Frontiers in psychiatry. vol 12. 2021-08-24. PMID:34421682. |
guo and imi reversed the obx-induced hyperlocomotion and recognition memory impairment, hippocampal bdnf increase, and redox imbalance (ros, no, and gsh levels). |
2021-08-24 |
2023-08-13 |
mouse |
| Sayna Bagheri, Kamyar Moradi, Elnaz Ehghaghi, Abolfazl Badripour, Mohammad Keykhaei, Amir Ashraf-Ganjouei, Mana Moassefi, Shahriar Faghani, Ahmad Reza Dehpou. Melatonin improves learning and memory of mice with chronic social isolation stress via an interaction between microglia polarization and BDNF/TrkB/CREB signaling pathway. European journal of pharmacology. vol 908. 2021-08-20. PMID:34289399. |
hippocampus samples were obtained and the expressions of bdnf, trkb, phosphorylated trkb (ptrkb), creb, phosphorylated creb (pcreb), as well as m1 and m2 microglia were assessed. |
2021-08-20 |
2023-08-13 |
mouse |
| Fatemeh Mansouri, Hamideh Ghanbari, Narges Marefati, Zohre Arab, Hossein Salmani, Farimah Beheshti, Mahmoud Hossein. Protective effects of vitamin D on learning and memory deficit induced by scopolamine in male rats: the roles of brain-derived neurotrophic factor and oxidative stress. Naunyn-Schmiedeberg's archives of pharmacology. vol 394. issue 7. 2021-08-19. PMID:33649977. |
the cortical and hippocampal tissues were analyzed for bdnf, catalase (cat), and superoxide dismutase (sod) activities, thiol content, no metabolites, and malondialdehyde (mda) concentration. |
2021-08-19 |
2023-08-13 |
rat |
| Shao-Han Chang, Ying Hao Yu, Alan He, Chen Yin Ou, Bai Chuang Shyu, Andrew Chih Wei Huan. BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model. Behavioural neurology. vol 2021. 2021-08-18. PMID:33763156. |
bdnf protein and bdnf mrna expression of the medial prefrontal cortex, amygdala, and hippocampus during situational reminder in the ptsd animal model. |
2021-08-18 |
2023-08-13 |
rat |
| Shao-Han Chang, Ying Hao Yu, Alan He, Chen Yin Ou, Bai Chuang Shyu, Andrew Chih Wei Huan. BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model. Behavioural neurology. vol 2021. 2021-08-18. PMID:33763156. |
whether bdnf protein and bdnf mrna expression of the medial prefrontal cortex (mpfc; cingulated cortex area 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), amygdala, and hippocampus (ca1, ca2, ca3, and dentate gyrus (dg)) was involved in fear of posttraumatic stress disorder (ptsd) during the situational reminder of traumatic memory remains uncertain. |
2021-08-18 |
2023-08-13 |
rat |
| Shao-Han Chang, Ying Hao Yu, Alan He, Chen Yin Ou, Bai Chuang Shyu, Andrew Chih Wei Huan. BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model. Behavioural neurology. vol 2021. 2021-08-18. PMID:33763156. |
bdnf mrna levels were higher in the mpfc and amygdala but lower in the hippocampus. |
2021-08-18 |
2023-08-13 |
rat |
| Shao-Han Chang, Ying Hao Yu, Alan He, Chen Yin Ou, Bai Chuang Shyu, Andrew Chih Wei Huan. BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model. Behavioural neurology. vol 2021. 2021-08-18. PMID:33763156. |
the neural connection analysis showed that bdnf protein and bdnf mrna exhibited weak connections among the mpfc, amygdala, and hippocampus during situational reminders. |
2021-08-18 |
2023-08-13 |
rat |
| Rui Wei, Lin Zhang, Wei Hu, Xinying Shang, Yuyan He, Wei Zhan. Zeb2/Axin2-Enriched BMSC-Derived Exosomes Promote Post-Stroke Functional Recovery by Enhancing Neurogenesis and Neural Plasticity. Journal of molecular neuroscience : MN. 2021-08-17. PMID:34401997. |
the number of neurons was increased in the subventricular zone (svz), hippocampus, and cortex area, while the expression of nerve growth factors (ngf, bdnf, etc.) |
2021-08-17 |
2023-08-13 |
rat |
| Jing Wang, Agustin Anastasia, Henrietta Bains, Joanna I Giza, David G Clossey, Jingjing Deng, Thomas A Neubert, William J Rice, Francis S Lee, Barbara L Hempstead, Clay Bracke. Zinc induced structural changes in the intrinsically disordered BDNF Met prodomain confer synaptic elimination. Metallomics : integrated biometal science. vol 12. issue 8. 2021-08-12. PMID:32744273. |
the bdnf met66 prodomain, but not the val66 prodomain, promotes rapid structural remodeling of hippocampal neurons' growth cones and dendritic spines by interacting directly with the sorcs2 receptor. |
2021-08-12 |
2023-08-13 |
human |
| Dany Khamsing, Solène Lebrun, Isabelle Fanget, Nathanaël Larochette, Christophe Tourain, Vincent de Sars, Maia Brunstein, Martin Oheim, Damien Carrel, François Darchen, Claire Desno. A role for BDNF- and NMDAR-induced lysosomal recruitment of mTORC1 in the regulation of neuronal mTORC1 activity. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34247625. |
in mouse hippocampal neurons, we observed that bdnf and treatments activating nmda receptors trigger a robust increase in mtorc1 activity. |
2021-08-12 |
2023-08-13 |
mouse |