| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cinthia R Correa, Claudia Schena, Samantha C Lopes, Rui D Prediger, E L Silva, Débora K R Venske, L C Ribeiro, J D Moreir. Combined effects of caloric restriction and fish oil attenuated anti-depressant and anxiolytic-like effects of fish oil: association with hippocampal BDNF concentrations. Behavioural brain research. vol 393. 2021-10-04. PMID:32561388. |
there was a positive association between the number of entries in the platform quadrant in the mwm and hippocampal bdnf concentrations (β = 0.39; r² = 0.15; p = 0.042) and an inverse association between forced swim immobility time and bdnf concentrations (β = -0.39; r² = 0.15; p = 0.041). |
2021-10-04 |
2023-08-13 |
rat |
| Cinthia R Correa, Claudia Schena, Samantha C Lopes, Rui D Prediger, E L Silva, Débora K R Venske, L C Ribeiro, J D Moreir. Combined effects of caloric restriction and fish oil attenuated anti-depressant and anxiolytic-like effects of fish oil: association with hippocampal BDNF concentrations. Behavioural brain research. vol 393. 2021-10-04. PMID:32561388. |
synergic effects of interventions attenuated fo-related behavioral responses and bdnf concentrations and probably reduced hippocampal neuroplasticity. |
2021-10-04 |
2023-08-13 |
rat |
| Majid Motaghinejad, Roya Mashayekh, Manijeh Motevalian, Sepideh Safar. The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences. Fundamental & clinical pharmacology. vol 35. issue 1. 2021-10-04. PMID:32579730. |
hippocampal neurodegenerative and histological parameters as well as cyclic amp response element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) levels were assessed. |
2021-10-04 |
2023-08-13 |
human |
| Majid Motaghinejad, Roya Mashayekh, Manijeh Motevalian, Sepideh Safar. The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences. Fundamental & clinical pharmacology. vol 35. issue 1. 2021-10-04. PMID:32579730. |
additionally, alcohol administration boosted lipid peroxidation and levels of glutathione in oxidized form (gssg), tumor necrosis factor alpha (tnf-α), interleukin 1 beta (il-1β), and bax protein, while decreased reducing type of glutathione (gsh), bcl-2 protein, phosphorylated creb, and bdnf levels in rat hippocampus. |
2021-10-04 |
2023-08-13 |
human |
| Majid Motaghinejad, Roya Mashayekh, Manijeh Motevalian, Sepideh Safar. The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences. Fundamental & clinical pharmacology. vol 35. issue 1. 2021-10-04. PMID:32579730. |
in comparison, minocycline attenuated alcohol-induced neurodegeneration; elevating expression levels of p-creb and bdnf and inhibited alcohol induced histopathological changes in both dentate gyrus (dg) and ca1 of hippocampus. |
2021-10-04 |
2023-08-13 |
human |
| Farimah Beheshti, Hamid Reza Akbari, Yousef Baghcheghi, Fatemeh Mansouritorghabeh, Sakineh Sadat Mortazavi Sani, Mahmoud Hossein. Beneficial effects of angiotensin converting enzyme inhibition on scopolamine-induced learning and memory impairment in rats, the roles of brain-derived neurotrophic factor, nitric oxide and neuroinflammation. Clinical and experimental hypertension (New York, N.Y. : 1993). vol 43. issue 6. 2021-10-04. PMID:33724113. |
in this study, the effects of ras inhibitor captopril (capto) on hippocampal bdnf, interleukin -6 (il-6), oxidative stress indicators, and nitric oxide (no) in scopolamine (sco)-induced memory impairment in rats were examined. |
2021-10-04 |
2023-08-13 |
rat |
| Blanca Marin Bosch, Aurélien Bringard, Maria G Logrieco, Estelle Lauer, Nathalie Imobersteg, Aurélien Thomas, Guido Ferretti, Sophie Schwartz, Kinga Iglo. A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34257382. |
regular physical exercise enhances memory functions, synaptic plasticity in the hippocampus, and brain derived neurotrophic factor (bdnf) levels. |
2021-10-04 |
2023-08-13 |
human |
| Blanca Marin Bosch, Aurélien Bringard, Maria G Logrieco, Estelle Lauer, Nathalie Imobersteg, Aurélien Thomas, Guido Ferretti, Sophie Schwartz, Kinga Iglo. A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34257382. |
likewise, short periods of exercise, or acute exercise, benefit hippocampal plasticity in rodents, via increased endocannabinoids (especially anandamide, aea) and bdnf release. |
2021-10-04 |
2023-08-13 |
human |
| Blanca Marin Bosch, Aurélien Bringard, Maria G Logrieco, Estelle Lauer, Nathalie Imobersteg, Aurélien Thomas, Guido Ferretti, Sophie Schwartz, Kinga Iglo. A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34257382. |
memory after moderate intensity exercise correlated with exercise-induced increases in both aea and bndf levels: while aea was associated with hippocampal activity during memory recall, bdnf enhanced hippocampal memory representations and long-term performance. |
2021-10-04 |
2023-08-13 |
human |
| Xiuli Zhai, Jinying Li, Liya Li, Ye Sun, Xiaonan Zhang, Ying Xue, Jiaxin Lv, Ye Gao, Shouxin Li, Wei Yan, Shengming Yin, Zhaoyang Xia. L-lactate preconditioning promotes plasticity-related proteins expression and reduces neurological deficits by potentiating GPR81 signaling in rat traumatic brain injury model. Brain research. vol 1746. 2021-10-01. PMID:32531223. |
l-lactate preconditioning significantly increased the expression of gpr81, psd95, gap43, bdnf, and mct2 24 h after tbi in the cortex and hippocampus compared with the sham group. |
2021-10-01 |
2023-08-13 |
rat |
| Hajime Miyanishi, Atsumi Nitt. A Role of BDNF in the Depression Pathogenesis and a Potential Target as Antidepressant: The Modulator of Stress Sensitivity "Shati/Nat8l-BDNF System" in the Dorsal Striatum. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577589. |
we reviewed a novel finding of bdnf function in the dorsal striatum, which induces vulnerability to social stress, in addition to recent research progress regarding the brain regional functions of bdnf, including the prefrontal cortex, hippocampus, and nucleus accumbens. |
2021-10-01 |
2023-08-13 |
Not clear |
| Ruizhuo Chen, Aidan S Weitzner, Lara A McKennon, Laura K Fonke. Chronic circadian phase advance in male mice induces depressive-like responses and suppresses neuroimmune activation. Brain, behavior, & immunity - health. vol 17. 2021-10-01. PMID:34589820. |
further, cpa suppressed expression of brain-derived neurotrophic factor (bdnf) and pro-inflammatory cytokine interleukin-1 beta in the hippocampus. |
2021-10-01 |
2023-08-13 |
mouse |
| Yangliang Yang, Jing Yi, Mengzhi Pan, Baoji Hu, Hongwei Dua. Edaravone alleviated propofol-induced neural injury in developing rats by BDNF/TrkB pathway. Journal of cellular and molecular medicine. vol 25. issue 11. 2021-09-30. PMID:33932098. |
additionally, the intraperitoneal injection of edaravone, the intraperitoneal injection of the brain-derived neurotrophic factor (bdnf)-mimicking small compound (7,8 dihydroxyflavone) and the intracranial injection of the exogenous bdnf were all respectively effective in alleviating the propofol-induced neural apoptosis and inflammation in the hippocampus. |
2021-09-30 |
2023-08-13 |
rat |
| Guangchi Sun, Zong Miao, Yangfan Ye, Pengzhan Zhao, Liang Fan, Zhongyuan Bao, Yiming Tu, Chong Li, Honglu Chao, Xiupeng Xu, Jing J. Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury. Brain research bulletin. vol 162. 2021-09-29. PMID:32502596. |
the tropomyosin receptor kinase b (trkb) inhibitor, ana-12, was used to test the role of the brain-derived neurotrophic factor (bdnf)/ trkb/phosphoinositide 3-kinase (pi3k)/akt signaling pathway in regulating inflammation and neurogenesis in the hippocampus. |
2021-09-29 |
2023-08-13 |
rat |
| Jana Tchekalarova, Milena Atanasova, Natasha Ivanova, Nickolay Boyadjiev, Rumyana Mitreva, Katerina Georgiev. Endurance training exerts time-dependent modulation on depressive responses and circadian rhythms of corticosterone and BDNF in the rats with pinealectomy. Brain research bulletin. vol 162. 2021-09-29. PMID:32505509. |
we tested the hypothesis that endurance training can have a beneficial impact on depressive behavior induced by pinealectomy in rat via correction of desynchronized circadian rhythms of corticosterone secretion in plasma and brain-derived neurothrophic factor (bdnf) in the hippocampus. |
2021-09-29 |
2023-08-13 |
rat |
| Jana Tchekalarova, Milena Atanasova, Natasha Ivanova, Nickolay Boyadjiev, Rumyana Mitreva, Katerina Georgiev. Endurance training exerts time-dependent modulation on depressive responses and circadian rhythms of corticosterone and BDNF in the rats with pinealectomy. Brain research bulletin. vol 162. 2021-09-29. PMID:32505509. |
these findings suggest that the antidepressant-like effect of endurance training might be mediated via correction of the disturbed circadian rhythm of corticosterone release and enhancement of hippocampal bdnf levels in rats with pinealectomy. |
2021-09-29 |
2023-08-13 |
rat |
| Hong-Mei Niu, Deng-Lei Ma, Ming-Yang Wang, Xiao-Ping Chen, Li Zhang, Ya-Li Li, Lan Zhang, Lin L. Epimedium flavonoids protect neurons and synapses in the brain via activating NRG1/ErbB4 and BDNF/Fyn signaling pathways in a chronic cerebral hypoperfusion rat model. Brain research bulletin. vol 162. 2021-09-29. PMID:32592805. |
in addition, ef increased the expression of neuregulin-1 (nrg-1), p-erbb4, brain-derived neurotrophic factor (bdnf), p-fyn, pi3k, p-akt, and p-creb in the hippocampus of 2vo rats. |
2021-09-29 |
2023-08-13 |
rat |
| Lei Cao-Lei, Sandra Yogendran, Romane Dufoix, Guillaume Elgbeili, David P Laplante, Suzanne Kin. Prenatal Maternal Stress From a Natural Disaster and Hippocampal Volumes: Gene-by-Environment Interactions in Young Adolescents From Project Ice Storm. Frontiers in behavioral neuroscience. vol 15. 2021-09-29. PMID:34566593. |
hence, we investigated the role of genetic variants of two snps that are candidates to moderate the effects of pnms on hippocampal volume: comt (rs4680) and bdnf (rs6265). |
2021-09-29 |
2023-08-13 |
human |
| Priscila B Rosa, Luis E B Bettio, Vivian B Neis, Morgana Moretti, Fernanda N Kaufmann, Mauren K Tavares, Isabel Werle, Yasmim Dalsenter, Nicolle Platt, Axel F Rosado, Daiane B Fraga, Isabella A Heinrich, Andiara E Freitas, Rodrigo B Leal, Ana Lúcia S Rodrigue. Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling. Purinergic signalling. vol 17. issue 2. 2021-09-28. PMID:33712981. |
we also evaluated if the antidepressant-like effect of guanosine is accompanied by an acute increase in hippocampal and prefrontocortical bdnf levels. |
2021-09-28 |
2023-08-13 |
mouse |
| Priscila B Rosa, Luis E B Bettio, Vivian B Neis, Morgana Moretti, Fernanda N Kaufmann, Mauren K Tavares, Isabel Werle, Yasmim Dalsenter, Nicolle Platt, Axel F Rosado, Daiane B Fraga, Isabella A Heinrich, Andiara E Freitas, Rodrigo B Leal, Ana Lúcia S Rodrigue. Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling. Purinergic signalling. vol 17. issue 2. 2021-09-28. PMID:33712981. |
guanosine exerted an antidepressant-like effect 1, 6, and 24 h after its administration, an effect accompanied by increased hippocampal bdnf level. |
2021-09-28 |
2023-08-13 |
mouse |