| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sara Pereira Silva, José Ivo Araújo Beserra-Filho, Melina Chiemi Kubota, Gabriela Nascimento Cardoso, Francisca Rayanne Silva Freitas, Bianca Santos Martins Gonçalves, Wilson Vicente-Silva, Suellen Silva-Martins, Ana Claúdia Custódio-Silva, Beatriz Soares-Silva, Amanda Maria-Macêdo, José Ronaldo Santos, Debora Estadella, Alessandra Mussi Ribeir. Palatable high-fat diet intake influences mnemonic and emotional aspects in female rats in an estrous cycle-dependent manner. Metabolic brain disease. vol 36. issue 7. 2021-09-14. PMID:34406559. |
furthermore, th-immunoreactivity decreased in the dorsal striatum and bdnf in the hippocampus in hfd-fed females. |
2021-09-14 |
2023-08-13 |
rat |
| Michael Di Palma, Stefano Sartini, Davide Lattanzi, Riccardo Cuppini, Mariana Pita-Rodriguez, Yoslandy Diaz-Carmenate, Manuel Narvaez, Kjell Fuxe, Dasiel O Borroto-Escuela, Patrizia Ambrogin. Evidence for the existence of A2AR-TrkB heteroreceptor complexes in the dorsal hippocampus of the rat brain: Potential implications of A2AR and TrkB interplay upon ageing. Mechanisms of ageing and development. vol 190. 2021-09-13. PMID:32565059. |
adenosine a2a receptors (a2ar) are crucial in facilitating the bdnf action on synaptic transmission in the rat hippocampus primarily upon ageing. |
2021-09-13 |
2023-08-13 |
rat |
| Michael Di Palma, Stefano Sartini, Davide Lattanzi, Riccardo Cuppini, Mariana Pita-Rodriguez, Yoslandy Diaz-Carmenate, Manuel Narvaez, Kjell Fuxe, Dasiel O Borroto-Escuela, Patrizia Ambrogin. Evidence for the existence of A2AR-TrkB heteroreceptor complexes in the dorsal hippocampus of the rat brain: Potential implications of A2AR and TrkB interplay upon ageing. Mechanisms of ageing and development. vol 190. 2021-09-13. PMID:32565059. |
furthermore, it has been suggested that a2ar-tropomyosin related kinase b receptor (trkb) crosstalk has a pivotal role in adenosine a2ar-mediated modulation of the bdnf action on hippocampal plasticity. |
2021-09-13 |
2023-08-13 |
rat |
| Michael Di Palma, Stefano Sartini, Davide Lattanzi, Riccardo Cuppini, Mariana Pita-Rodriguez, Yoslandy Diaz-Carmenate, Manuel Narvaez, Kjell Fuxe, Dasiel O Borroto-Escuela, Patrizia Ambrogin. Evidence for the existence of A2AR-TrkB heteroreceptor complexes in the dorsal hippocampus of the rat brain: Potential implications of A2AR and TrkB interplay upon ageing. Mechanisms of ageing and development. vol 190. 2021-09-13. PMID:32565059. |
their allosteric receptor-receptor interactions may significantly modulate bdnf signaling impacting on hippocampal plasticity which is impaired upon ageing. |
2021-09-13 |
2023-08-13 |
rat |
| Hovy Ho-Wai Wong, Olivier Camiré, P Jesper Sjöströ. The secret life of memory receptors. eLife. vol 10. 2021-09-13. PMID:34259634. |
the canonical hippocampal nmda memory receptor also controls the release of the transmitter glutamate and the growth factor bdnf. |
2021-09-13 |
2023-08-13 |
Not clear |
| Frideriki Poutoglidou, Chryssa Pourzitaki, Maria Eleni Manthou, Athanasios Saitis, Foteini Malliou, Dimitrios Kouvela. Infliximab and Tocilizumab Reduce Anxiety-Like Behaviour and Improve Cognitive Performance in a Juvenile Collagen-Induced Arthritis Rat Model. Inflammation. 2021-09-13. PMID:34515956. |
also, the expression of brain-derived neurotrophic factor (bdnf), a biomarker associated with neuronal survival and plasticity, was determined in the hippocampus and the amygdala by rt-qpcr. |
2021-09-13 |
2023-08-13 |
rat |
| Roberta Ströher Toledo, Dirson João Stein, Paulo Roberto Stefani Sanches, Andressa de Souza, Lisiane Santos da Silva, Helouise Richardt Medeiros, Mayra Angélica de Souza Antunes, Josimar Macedo de Castro, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Repetitive Transcranial Magnetic Stimulation (rTMS) Reverses the Long-term Memory Impairment and the Decrease of Hippocampal Interleukin-10 Levels, both Induced by Neuropathic Pain in Rats. Neuroscience. vol 472. 2021-09-10. PMID:34358630. |
the objective of this study was to evaluate rtms treatment over long term memory (ltm) and hippocampal bdnf and il-10 levels in rats submitted to a np model. |
2021-09-10 |
2023-08-13 |
rat |
| Roberta Ströher Toledo, Dirson João Stein, Paulo Roberto Stefani Sanches, Andressa de Souza, Lisiane Santos da Silva, Helouise Richardt Medeiros, Mayra Angélica de Souza Antunes, Josimar Macedo de Castro, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Repetitive Transcranial Magnetic Stimulation (rTMS) Reverses the Long-term Memory Impairment and the Decrease of Hippocampal Interleukin-10 Levels, both Induced by Neuropathic Pain in Rats. Neuroscience. vol 472. 2021-09-10. PMID:34358630. |
biochemical assays (bdnf and il-10 levels) were performed in hippocampus tissue homogenates. |
2021-09-10 |
2023-08-13 |
rat |
| Narges Marefati, Farimah Beheshti, Sara Memarpour, Reza Bayat, Mohammad Naser Shafei, Hamid Reza Sadeghnia, Hamed Ghazavi, Mahmoud Hossein. The effects of acetyl-11-keto-β-boswellic acid on brain cytokines and memory impairment induced by lipopolysaccharide in rats. Cytokine. vol 131. 2021-09-08. PMID:32380425. |
pre-treatment by akba improved the levels of hippocampal il-10 (p < 0.001), bdnf (p < 0.001), cat (p < 0.05 and p < 0.001), sod p < 0.001 and thiols (p < 0.01 and p < 0.001) while reduced il-6 (p < 0.001), tnf-α (p < 0.001), no (p < 0.05 and p < 0.001), gfap (p < 0.001) and mda (p < 0.001) levels. |
2021-09-08 |
2023-08-13 |
rat |
| Frideriki Poutoglidou, Chryssa Pourzitaki, Maria Eleni Manthou, Athanasios Saitis, Foteini Malliou, Dimitrios Kouvela. Infliximab and tocilizumab reduce anxiety-like behavior, improve cognitive performance and reverse neuropathological alterations in juvenile rats with severe autoimmune arthritis. International immunopharmacology. vol 99. 2021-09-08. PMID:34217991. |
further, infliximab and tocilizumab treatment increased brain-derived neurotrophic factor (bdnf) expression in the hippocampal and amygdaloid area of rat brain. |
2021-09-08 |
2023-08-13 |
rat |
| Jing-Jing Chen, Jun-Xian Shen, Zong-Hao Yu, Chuan Pan, Fei Han, Xiu-Ling Zhu, Hui Xu, Rui-Ting Xu, Tong-Yao Wei, Ya-Ping L. The Antidepressant Effects of Resveratrol are Accompanied by the Attenuation of Dendrite/Dendritic Spine Loss and the Upregulation of BDNF/p-cofilin1 Levels in Chronic Restraint Mice. Neurochemical research. vol 46. issue 3. 2021-09-07. PMID:33392910. |
p-cofilin1 was significantly positively correlated with the overall dendritic spine density in mpfc as well as with the overall dendrite density or bdnf in the hippocampus. |
2021-09-07 |
2023-08-13 |
mouse |
| Jin Seung Choung, Jong Moon Kim, Myoung-Hwan Ko, Dong Sik Cho, MinYoung Ki. Therapeutic efficacy of repetitive transcranial magnetic stimulation in an animal model of Alzheimer's disease. Scientific reports. vol 11. issue 1. 2021-09-07. PMID:33432077. |
under in vitro conditions, aβ42 incubated mouse hippocampal cell showed an increase in dopamine levels and bdnf by application of high-frequency rtms treatment. |
2021-09-07 |
2023-08-13 |
mouse |
| Lucia Carboni, Luisa Ponzoni, Daniela Braida, Mariaelvina Sala, Cecilia Gotti, Michele Zol. Altered mRNA Levels of Stress-Related Peptides in Mouse Hippocampus and Caudate-Putamen in Withdrawal after Long-Term Intermittent Exposure to Tobacco Smoke or Electronic Cigarette Vapour. International journal of molecular sciences. vol 22. issue 2. 2021-09-07. PMID:33435320. |
withdrawal after exposure to e-cigarette vapour induced a 35% bdnf mrna decrease in the hippocampus, whereas bdnf was augmented by 118% by cigarette withdrawal in the cpu. |
2021-09-07 |
2023-08-13 |
mouse |
| Patrizia Pignataro, Manuela Dicarlo, Roberta Zerlotin, Chiara Zecca, Maria Teresa Dell'Abate, Cinzia Buccoliero, Giancarlo Logroscino, Silvia Colucci, Maria Gran. FNDC5/Irisin System in Neuroinflammation and Neurodegenerative Diseases: Update and Novel Perspective. International journal of molecular sciences. vol 22. issue 4. 2021-09-06. PMID:33562601. |
interestingly, in the hippocampus of mice, exercise increases fndc5 levels and upregulates brain-derived neurotrophic factor (bdnf) expression. |
2021-09-06 |
2023-08-13 |
mouse |
| Jian-Ping Zhu, Hua-Ying Wu, Yuan Zi, Xin-Bin Xia, Meng-Zhou Xie, Zhi-Ying Yua. Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-09-04. PMID:34475963. |
moreover, bht regulated bdnf expression in the hippocampus and improved intestinal flora deficits in cums rats by changing the content of |
2021-09-04 |
2023-08-13 |
rat |
| Helene A Fachim, Fabiana Corsi-Zuelli, Camila M Loureiro, Sri-Arun Iamjan, Rosana Shuhama, Samia Joca, Paulo Rossi Menezes, Adrian Heald, Paulo Louzada-Junior, Caroline F Dalton, Cristina Marta Del-Ben, Gavin P Reynold. Early-life stress effects on BDNF DNA methylation in first-episode psychosis and in rats reared in isolation. Progress in neuro-psychopharmacology & biological psychiatry. vol 108. 2021-09-02. PMID:33259836. |
dna was extracted from human blood and rat brain (prefrontal cortex and hippocampus), bisulphite-converted and the methylation of equivalent sequences within bdnf exon iv determined by pyrosequencing. |
2021-09-02 |
2023-08-13 |
human |
| Bettega Costa Lopes, Liciane Fernandes Medeiros, Dirson João Stein, Stefania Giotti Cioato, Vanessa Silva de Souza, Helouise Richardt Medeiros, Paulo Roberto Stefani Sanches, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. tDCS and exercise improve anxiety-like behavior and locomotion in chronic pain rats via modulation of neurotrophins and inflammatory mediators. Behavioural brain research. vol 404. 2021-09-02. PMID:33577881. |
bdnf, tnf-ɑ, and il-10 levels in the hippocampus, and bdnf, ngf, and il-10 levels in the sciatic nerve were assessed 48 h or 7 days after the end of treatment. |
2021-09-02 |
2023-08-13 |
rat |
| Mario Flores-Soto, Christian Romero-Guerrero, Nallely Vázquez-Hernández, Aldo Tejeda-Martínez, Fabiola L Martín-Amaya-Barajas, Sandra Orozco-Suárez, Ignacio González-Burgo. Pentylenetetrazol-induced seizures in adult rats are associated with plastic changes to the dendritic spines on hippocampal CA1 pyramidal neurons. Behavioural brain research. vol 406. 2021-09-02. PMID:33657439. |
however, the reduction in bdnf suggests that the activity of these spines would be down-regulated, may in part be responsible for the cognitive decline related to hippocampal function in patients with epilepsy. |
2021-09-02 |
2023-08-13 |
rat |
| Zhong-Xuan Ma, Ru-Yi Zhang, Wen-Juan Rui, Zhi-Qing Wang, Xia Fen. Quercetin alleviates chronic unpredictable mild stress-induced depressive-like behaviors by promoting adult hippocampal neurogenesis via FoxG1/CREB/ BDNF signaling pathway. Behavioural brain research. vol 406. 2021-09-02. PMID:33745981. |
quercetin alleviates chronic unpredictable mild stress-induced depressive-like behaviors by promoting adult hippocampal neurogenesis via foxg1/creb/ bdnf signaling pathway. |
2021-09-02 |
2023-08-13 |
mouse |
| Sinan Saral, Atilla Topçu, Mehmet Alkanat, Tolga Mercantepe, Kerimali Akyıldız, Lamiye Yıldız, Levent Tümkaya, Zihni Açar Yazıcı, Adnan Yılma. Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction. Behavioural brain research. vol 408. 2021-09-02. PMID:33845103. |
bdnf and the inflammatory cytokines tumor necrosis factor-α (tnf-α) and interleukin-1β (il-1β) levels were measured by elisa in hippocampal homogenates. |
2021-09-02 |
2023-08-13 |
rat |