| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samaneh Shamsipour, Gholamreza Sharifi, Farzaneh Taghia. Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease. Neuroscience letters. vol 756. 2021-06-22. PMID:33974953. |
impact of interval training with probiotic (l. plantarum / bifidobacterium bifidum) on passive avoidance test, chat and bdnf in the hippocampus of rats with alzheimer's disease. |
2021-06-22 |
2023-08-13 |
rat |
| Samaneh Shamsipour, Gholamreza Sharifi, Farzaneh Taghia. Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease. Neuroscience letters. vol 756. 2021-06-22. PMID:33974953. |
to take this line of research further, this study was aimed at investigating the impact of moderate-intensity interval training (miit) with a combined administration of lactobacillus plantarum and bifidobacterium bifidum (probiotic, brob) on the passive avoidance test (shuttle box), choline acetyltransferase (chat) and the brain derived neurotrophic factor (bdnf) in the hippocampus of a rat model of ad. |
2021-06-22 |
2023-08-13 |
rat |
| Samaneh Shamsipour, Gholamreza Sharifi, Farzaneh Taghia. Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease. Neuroscience letters. vol 756. 2021-06-22. PMID:33974953. |
bdnf and chat in the hippocampus were measured by real time pcr (rt-pcr) and immunohistochemistry (ihc), respectively. |
2021-06-22 |
2023-08-13 |
rat |
| Ge Wang, Hongyang Zhang, Jiancong Sun, Yuwei Zhang, Fen He, Juntao Zo. Cyclosporin A impairs neurogenesis and cognitive abilities in brain development via the IFN-γ-Shh-BDNF pathway. International immunopharmacology. vol 96. 2021-06-22. PMID:33993101. |
however, the shh pathway receptor agonist sag could block the impairment of cognitive ability and the decrease of hippocampal neurogenesis and brain-derived neurotrophic factor (bdnf) level induced by csa. |
2021-06-22 |
2023-08-13 |
Not clear |
| Min-Tae Jeon, Gyeong Joon Moon, Sehwan Kim, Minji Choi, Yong-Seok Oh, Dong Woon Kim, Hyung-Jun Kim, Kea Joo Lee, Youngshik Choe, Chang Man Ha, Il-Sung Jang, Michiko Nakamura, Catriona McLean, Won-Suk Chung, Won-Ho Shin, Seok-Geun Lee, Sang Ryong Ki. Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo. British journal of pharmacology. vol 177. issue 3. 2021-06-21. PMID:31658360. |
we recently reported that aav1-rheb(s16h) transduction could protect hippocampal neurons through the induction of brain-derived neurotrophic factor (bdnf) in the rat hippocampus in vivo. |
2021-06-21 |
2023-08-13 |
rat |
| Min-Tae Jeon, Gyeong Joon Moon, Sehwan Kim, Minji Choi, Yong-Seok Oh, Dong Woon Kim, Hyung-Jun Kim, Kea Joo Lee, Youngshik Choe, Chang Man Ha, Il-Sung Jang, Michiko Nakamura, Catriona McLean, Won-Suk Chung, Won-Ho Shin, Seok-Geun Lee, Sang Ryong Ki. Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo. British journal of pharmacology. vol 177. issue 3. 2021-06-21. PMID:31658360. |
it is still unclear how neuronal bdnf produced by aav1-rheb(s16h) transduction induces neuroprotective effects in the hippocampus and whether its up-regulation contributes to the enhance of a neuroprotective system in the adult brain. |
2021-06-21 |
2023-08-13 |
rat |
| Luiza P Géa, Eduarda D da Rosa, Bruna S Panizzutti, Érica Z de Aguiar, Larissa F de Oliveira, Pamela Ferrari, Angelo Piato, Rosane Gomez, Rafael Colombo, Adriane R Ros. Reduction of hippocampal IL-6 levels in LPS-injected rats following acute exendin-4 treatment. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 7. 2021-06-21. PMID:32363414. |
brain-derived neurotrophic factor (bdnf), thiobarbituric acid reactive species (tbars), and interleukin (il)-6 were quantified in the serum and hippocampus. |
2021-06-21 |
2023-08-13 |
rat |
| Luiza P Géa, Eduarda D da Rosa, Bruna S Panizzutti, Érica Z de Aguiar, Larissa F de Oliveira, Pamela Ferrari, Angelo Piato, Rosane Gomez, Rafael Colombo, Adriane R Ros. Reduction of hippocampal IL-6 levels in LPS-injected rats following acute exendin-4 treatment. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 7. 2021-06-21. PMID:32363414. |
bdnf hippocampal levels seemed to be increased in the lps+ex-4 0.5 group compared with lps+saline (p > 0.05). |
2021-06-21 |
2023-08-13 |
rat |
| Kohei Takahashi, Kazuhiro Kurokawa, Kazuya Miyagawa, Atsumi Mochida-Saito, Yukio Nemoto, Hiroyuki Iwasa, Osamu Nakagawasai, Takeshi Tadano, Hiroshi Takeda, Minoru Tsuj. Antidementia effects of Enterococcus faecalis 2001 are associated with enhancement of hippocampal neurogenesis via the ERK-CREB-BDNF pathway in olfactory bulbectomized mice. Physiology & behavior. vol 223. 2021-06-21. PMID:32502526. |
moreover, ef-2001 also recovered the reductions in p-erk1/2, p-creb, bdnf and dcx levels and in neurogenesis observed in the hippocampus of obx mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Hamideh Bashiri, Mohsen Enayati, Alireza Bashiri, Ali-Akbar Salar. Swimming exercise improves cognitive and behavioral disorders in male NMRI mice with sporadic Alzheimer-like disease. Physiology & behavior. vol 223. 2021-06-21. PMID:32522682. |
to understand the possible mechanisms, amyloid-β (aβ)-42, brain-derived neurotrophic factor (bdnf), glutamate, malondialdehyde (mda), tumor-necrosis-factor (tnf)-α, and interleukin (il)-6 levels were measured in the hippocampus. |
2021-06-21 |
2023-08-13 |
mouse |
| Hamideh Bashiri, Mohsen Enayati, Alireza Bashiri, Ali-Akbar Salar. Swimming exercise improves cognitive and behavioral disorders in male NMRI mice with sporadic Alzheimer-like disease. Physiology & behavior. vol 223. 2021-06-21. PMID:32522682. |
in contrast, swimming exercise significantly reversed these neurobehavioral disorders, increased bdnf, and decreased both glutamate and tnf-α in the hippocampus of stz-treated mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Semil Selcen Gocmez, Yusufhan Yazir, Gulcin Gacar, Tuğçe Demirtaş Şahin, Sertan Arkan, Ayşe Karson, Tijen Utka. Etanercept improves aging-induced cognitive deficits by reducing inflammation and vascular dysfunction in rats. Physiology & behavior. vol 224. 2021-06-21. PMID:32569601. |
thoracic enos expression, hippocampal bdnf expression and serum and hippocampal tnf levels were also measured. |
2021-06-21 |
2023-08-13 |
rat |
| Semil Selcen Gocmez, Yusufhan Yazir, Gulcin Gacar, Tuğçe Demirtaş Şahin, Sertan Arkan, Ayşe Karson, Tijen Utka. Etanercept improves aging-induced cognitive deficits by reducing inflammation and vascular dysfunction in rats. Physiology & behavior. vol 224. 2021-06-21. PMID:32569601. |
furthermore, aging resulted in endothelial dysfunction, decreased expressions of thoracic enos and hippocampal bdnf, and increased level of tnf in serum and hippocampus. |
2021-06-21 |
2023-08-13 |
rat |
| Fu Li, Haitao Xiang, Jiashu Lu, Zhuo Chen, Chao Huang, Xiaomei Yua. Lycopene ameliorates PTSD-like behaviors in mice and rebalances the neuroinflammatory response and oxidative stress in the brain. Physiology & behavior. vol 224. 2021-06-21. PMID:32592701. |
lycopene treatment (20 mg/kg, 12 days) also suppressed the sps-induced decrease in brain derived neurotrophic factor (bdnf) levels in the hippocampus and prefrontal cortex in mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Erin Wosnitzka, Xinsheng Nan, Jeff Nan, Pedro Chacón-Fernández, Lothar Kussmaul, Michael Schuler, Bastian Hengerer, Yves-Alain Bard. A New Mouse Line Reporting the Translation of Brain-Derived Neurotrophic Factor Using Green Fluorescent Protein. eNeuro. vol 7. issue 1. 2021-06-18. PMID:31882533. |
bdnf levels are very low in most brain areas, except for the large mossy fiber terminals in the hippocampus where bdnf accumulates at readily detectable levels. |
2021-06-18 |
2023-08-13 |
mouse |
| Rongfeng Qi, Yifeng Luo, Li Zhang, Yifei Weng, Wesley Surento, Lingjiang Li, Zhihong Cao, Guang Ming L. Effects of COMT rs4680 and BDNF rs6265 polymorphisms on brain degree centrality in Han Chinese adults who lost their only child. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32066722. |
these findings suggest that the modulatory effect of bdnf polymorphism on the mfg and hippocampus may contribute to ptsd development in bereaved adults. |
2021-06-18 |
2023-08-13 |
human |
| Lianghui Ni, Yanling Xu, Sixuan Dong, Yujia Kong, Hong Wang, Guohua Lu, Yanyu Wang, Qi Li, Changjiang Li, Zhongde Du, Hongwei Sun, Lin Su. The potential role of the HCN1 ion channel and BDNF-mTOR signaling pathways and synaptic transmission in the alleviation of PTSD. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32198387. |
a series of behavioral tests and biochemical assessments of certain proteins (hcn1, bdnf, and pmtor) and synaptic ultrastructure in the prefrontal cortex (pfc) and hippocampus (hip) were then conducted. |
2021-06-18 |
2023-08-13 |
rat |
| An-Rong Wang, Lian-Fang Mi, Zhi-Lei Zhang, Ming-Zhe Hu, Ze-Yu Zhao, Bin Liu, Yan-Bin Li, Shu Zhen. Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway. Behavioural brain research. vol 403. 2021-06-18. PMID:33493495. |
western blot and immunohistochemistry were adopted to evaluate expression of phosphorylated camp response element binding protein(p-creb), brain derived neurotrophic factor(bdnf) and apoptosis-related molecules in the dentate gyrus region of rat hippocampus. |
2021-06-18 |
2023-08-13 |
rat |
| An-Rong Wang, Lian-Fang Mi, Zhi-Lei Zhang, Ming-Zhe Hu, Ze-Yu Zhao, Bin Liu, Yan-Bin Li, Shu Zhen. Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway. Behavioural brain research. vol 403. 2021-06-18. PMID:33493495. |
administration of saikosaponin a significantly ameliorated depressive-like behavior, and inhibited neuronal apoptosis, enhanced the level of p-creb, bdnf and bcl-2, reduced the level of bax, caspase-3 in the hippocampus of psd rats. |
2021-06-18 |
2023-08-13 |
rat |
| An-Rong Wang, Lian-Fang Mi, Zhi-Lei Zhang, Ming-Zhe Hu, Ze-Yu Zhao, Bin Liu, Yan-Bin Li, Shu Zhen. Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway. Behavioural brain research. vol 403. 2021-06-18. PMID:33493495. |
these results revealed that saikosaponin a improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia, presumably through increasing the expression of bdnf, p-creb and bcl-2, as well as decreasing the level of bax, caspase-3. |
2021-06-18 |
2023-08-13 |
rat |