| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Anna Lech, Monika Leśkiewicz, Kinga Kamińska, Zofia Rogóż, Elżbieta Lorenc-Koc. Glutathione Deficiency during Early Postnatal Development Causes Schizophrenia-Like Symptoms and a Reduction in BDNF Levels in the Cortex and Hippocampus of Adult Sprague-Dawley Rats. International journal of molecular sciences. vol 22. issue 12. 2021-07-26. PMID:34201038. |
glutathione deficiency during early postnatal development causes schizophrenia-like symptoms and a reduction in bdnf levels in the cortex and hippocampus of adult sprague-dawley rats. |
2021-07-26 |
2023-08-13 |
rat |
| Tatiana A Gudasheva, Anna V Tallerova, Armen G Mezhlumyan, Tatyana A Antipova, Ilya O Logvinov, Yulia N Firsova, Polina Y Povarnina, Sergey B Seredeni. Low-Molecular Weight BDNF Mimetic, Dimeric Dipeptide GSB-106, Reverses Depressive Symptoms in Mouse Chronic Social Defeat Stress. Biomolecules. vol 11. issue 2. 2021-07-23. PMID:33578683. |
thus, the present results demonstrate the dipeptide bdnf mimetic gsb-106 reversed depressive-like behavior and restored hippocampal neuroplasticity in a rodent depression model. |
2021-07-23 |
2023-08-13 |
mouse |
| Hien Luong, Sarojini Singh, Mallikarjun Patil, Prasanna Krishnamurth. Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice. American journal of physiology. Heart and circulatory physiology. vol 320. issue 5. 2021-07-23. PMID:33834865. |
mice in the cms group show a significant decrease in protein expression of hippocampal brain-derived neurotrophic factor (bdnf) and exhibit depression-like behavioral changes, such as learned helplessness and decreased exploration behavior, as compared with the control group. |
2021-07-23 |
2023-08-13 |
mouse |
| Xiao-Chen Yu, Zhen Li, Xin-Ran Liu, Jia-Ni Hu, Rui Liu, Na Zhu, Yong L. The Antioxidant Effects of Whey Protein Peptide on Learning and Memory Improvement in Aging Mice Models. Nutrients. vol 13. issue 6. 2021-07-23. PMID:34205338. |
its specific mechanism may be related to reducing the degeneration of hippocampal nerve cells, reducing the apoptosis of nerve cells, improving the activity of ache, reducing the expression of inflammatory factors (tnf-α and il-1β) in brain tissue, reducing oxidative stress injury, and improving the expression of p-camkⅡ and bdnf synaptic plasticity protein. |
2021-07-23 |
2023-08-13 |
mouse |
| Virendra Tiwari, Akanksha Mishra, Sonu Singh, Sandeep Kumar Mishra, Kiran Kumari Sahu, Parul, Mahesh J Kulkarni, Rakesh Shukla, Shubha Shukl. Protriptyline improves spatial memory and reduces oxidative damage by regulating NFκB-BDNF/CREB signaling axis in streptozotocin-induced rat model of Alzheimer's disease. Brain research. vol 1754. 2021-07-22. PMID:33422534. |
stz induced impairment in spatial learning and retention memory was associated with increased nfκb and reduced creb and bdnf expression in cortex and hippocampus. |
2021-07-22 |
2023-08-13 |
rat |
| Daniel A Paredes, Ahmad Jalloh, Briony J Catlow, Amritha Jaishankar, Seungmae Seo, Dennisse V Jimenez, Keri Martinowich, Marcelo Diaz-Bustamante, Daniel J Hoeppner, Ronald D G McKa. Bdnf deficiency in the neonatal hippocampus contributes to global dna hypomethylation and adult behavioral changes. Brain research. vol 1754. 2021-07-22. PMID:33422542. |
bdnf deficiency in the neonatal hippocampus contributes to global dna hypomethylation and adult behavioral changes. |
2021-07-22 |
2023-08-13 |
Not clear |
| Daniel A Paredes, Ahmad Jalloh, Briony J Catlow, Amritha Jaishankar, Seungmae Seo, Dennisse V Jimenez, Keri Martinowich, Marcelo Diaz-Bustamante, Daniel J Hoeppner, Ronald D G McKa. Bdnf deficiency in the neonatal hippocampus contributes to global dna hypomethylation and adult behavioral changes. Brain research. vol 1754. 2021-07-22. PMID:33422542. |
here we provide in vivo evidence that transient pharmacological inactivation of the hippocampus via tetrodotoxin microinjections or a genetic reduction in brain derived neurotrophic factor (bdnf) protein levels (bdnf |
2021-07-22 |
2023-08-13 |
Not clear |
| Chuan-An Yi, Yu-Hong Jiang, Ye Wang, Yu-Xian Li, Shi-Chang Cai, Xiu-Yu Wu, Xiang-Shang Hu, Xing-Guang Wa. Black Bamboo Rhizome Extract Improves Cognitive Dysfunction by Upregulating the Expression of Hippocampal BDNF and CREB in Rats with Cerebral Ischaemia-Reperfusion Injury. Neuropsychiatric disease and treatment. vol 17. 2021-07-22. PMID:34285486. |
black bamboo rhizome extract improves cognitive dysfunction by upregulating the expression of hippocampal bdnf and creb in rats with cerebral ischaemia-reperfusion injury. |
2021-07-22 |
2023-08-13 |
rat |
| Michael Zhang, Haley F Spencer, Rina Y Berman, Kennett D Radford, Kwang H Cho. Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats. IBRO neuroscience reports. vol 11. 2021-07-22. PMID:34286313. |
two hours after the infusion, brain tissue was dissected to obtain the medial prefrontal cortex (mpfc), hippocampus including the ca1, ca3, and dentate gyrus, and amygdala followed by western blot analyses of a transcription factor (c-fos), brain-derived neurotrophic factor (bdnf), and phosphorylated extracellular signal-regulated kinase (perk). |
2021-07-22 |
2023-08-13 |
rat |
| Michael Zhang, Haley F Spencer, Rina Y Berman, Kennett D Radford, Kwang H Cho. Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats. IBRO neuroscience reports. vol 11. 2021-07-22. PMID:34286313. |
in the hippocampus, 10 mg/kg ketamine reduced bdnf levels in male, but not female, rats. |
2021-07-22 |
2023-08-13 |
rat |
| Yoonju Kim, Youn-Jung Ki. Effect of Obesity on Cognitive Impairment in Vascular Dementia Rat Model via BDNF-ERK-CREB Pathway. Biological research for nursing. vol 23. issue 2. 2021-07-21. PMID:32844660. |
we also evaluated brain-derived neurotrophic factor (bdnf), phosphorylated extracellular signal-regulated kinase (perk), and phosphorylated cyclic adenosine monophosphate response element-binding protein (pcreb) in the hippocampus. |
2021-07-21 |
2023-08-13 |
rat |
| Mohadeseh Chahkandi, Gholamreza Komeili, Gholamreza Sepehri, Mohammad Khaksari, Sedigheh Amiresmail. Marijuana and β-estradiol interactions on spatial learning and memory in young female rats: Lack of role of the G protein-coupled estrogen receptor (GPR30). Life sciences. vol 280. 2021-07-20. PMID:34146552. |
we also assessed the bdnf (brain-derived neurotrophic factor) concentration and the hippocampal level of gpr30. |
2021-07-20 |
2023-08-13 |
rat |
| Myoung-Gwi Ryou, Xiaoan Chen, Ming Cai, Hong Wang, Marianna E Jung, Daniel B Metzger, Robert T Mallet, Xiangrong Sh. Intermittent Hypoxia Training Prevents Deficient Learning-Memory Behavior in Mice Modeling Alzheimer's Disease: A Pilot Study. Frontiers in aging neuroscience. vol 13. 2021-07-20. PMID:34276338. |
this study tested the hypothesis that iht improves learning-memory behavior, diminishes aβ accumulation in cerebral cortex and hippocampus, and enhances cerebrocortical contents of the neuroprotective trophic factors erythropoietin and brain-derived neurotrophic factor (bdnf) in mice manifesting ad traits. |
2021-07-20 |
2023-08-13 |
mouse |
| Yang Gao, Bailiu Ya, Xiaojin Li, Yan Guo, Haiyan Yi. Myricitrin ameliorates cognitive deficits in MCAO cerebral stroke rats via histone acetylation-induced alterations of brain-derived neurotrophic factor. Molecular and cellular biochemistry. vol 476. issue 2. 2021-07-19. PMID:33074446. |
at a dose of 30 mg/kg myricitrin, the histone deacetylase content was decreased, the expression levels of bdnf were increased, the levels of acetylated h3 and h4 along with syn-i in the hippocampus region were over-expressed compared to control vehicle-treated rats. |
2021-07-19 |
2023-08-13 |
rat |
| Bo Jiang, Wenhui Yang, Zhilong Xiu, Liuwei Zhang, Xinxiu Ren, Lijun Wang, Lei Chen, Tetsuya Asakaw. An in vivo explorative study to observe the protective effects of Puerariae flos extract on chronic ethanol exposure and withdrawal male mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 137. 2021-07-19. PMID:33524786. |
the changes of neuropsychological behaviors; hippocampal bdnf expression and ca1 neuronal density; and plasma corticotropin-releasing hormone (crh), acth, and cort levels were observed. |
2021-07-19 |
2023-08-13 |
mouse |
| Bo Jiang, Wenhui Yang, Zhilong Xiu, Liuwei Zhang, Xinxiu Ren, Lijun Wang, Lei Chen, Tetsuya Asakaw. An in vivo explorative study to observe the protective effects of Puerariae flos extract on chronic ethanol exposure and withdrawal male mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 137. 2021-07-19. PMID:33524786. |
hippocampal bdnf expression was significantly downregulated by etoh exposure and upregulated by withdrawal. |
2021-07-19 |
2023-08-13 |
mouse |
| Bo Jiang, Wenhui Yang, Zhilong Xiu, Liuwei Zhang, Xinxiu Ren, Lijun Wang, Lei Chen, Tetsuya Asakaw. An in vivo explorative study to observe the protective effects of Puerariae flos extract on chronic ethanol exposure and withdrawal male mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 137. 2021-07-19. PMID:33524786. |
the results of this study also indicated a complicated scenario of neuropsychological behaviors, hippocampal bdnf expression, and hypothalamic-pituitary-adrenal axis which are affected by the timing of etoh exposure and withdrawal. |
2021-07-19 |
2023-08-13 |
mouse |
| Ya-Hui Xu, Xin-Xing Wang, Ming-Jing Wang, Yue-Yun Liu, Zhe Xue, Jia-Xu Che. Influence of progestational stress on BDNF and NMDARs in the hippocampus of male offspring and amelioration by Chaihu Shugan San. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 135. 2021-07-19. PMID:33548869. |
influence of progestational stress on bdnf and nmdars in the hippocampus of male offspring and amelioration by chaihu shugan san. |
2021-07-19 |
2023-08-13 |
Not clear |
| Ya-Hui Xu, Xin-Xing Wang, Ming-Jing Wang, Yue-Yun Liu, Zhe Xue, Jia-Xu Che. Influence of progestational stress on BDNF and NMDARs in the hippocampus of male offspring and amelioration by Chaihu Shugan San. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 135. 2021-07-19. PMID:33548869. |
however, whether chaihu shugan san (css) can ameliorate hippocampal neural development via the regulation of brain-derived neurotrophic factor (bdnf), and n-methyl-d-aspartate receptors (nmdar) 2a (nr2a) and 2b (nr2b), and the mechanism of such action remains unclear. |
2021-07-19 |
2023-08-13 |
Not clear |
| Basem H Elesawy, Walaa F Alsanie, Mubarak Ali Algahtany, Jawaher M Al-Ashkhari, Aya K Alyarobi, Hussein F Sak. Whole and refined grains change behavior and reduce brain derived neurotrophic factor and neurotrophin-3 in rats. Journal of food biochemistry. 2021-07-19. PMID:34278588. |
after 12 weeks, we measured the hippocampal and prefrontal cortical brain derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), 5-hydroxytryptamine, dopamine, norepinephrine, malondialdehyde (mda) and reduced glutathione (gsh) levels. |
2021-07-19 |
2023-08-13 |
rat |