| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Basem H Elesawy, Walaa F Alsanie, Mubarak Ali Algahtany, Jawaher M Al-Ashkhari, Aya K Alyarobi, Hussein F Sak. Whole and refined grains change behavior and reduce brain derived neurotrophic factor and neurotrophin-3 in rats. Journal of food biochemistry. 2021-07-19. PMID:34278588. |
the rats on a diet of whole and refined grains had low bdnf, nt-3, norepinephrine, dopamine and serotonin significantly (p < .01) in both the hippocampus and prefrontal cortex as compared to control rats. |
2021-07-19 |
2023-08-13 |
rat |
| S Alex Marshall, Justin A McClain, Jessica I Wooden, Kimberly Nixo. Microglia Dystrophy Following Binge-Like Alcohol Exposure in Adolescent and Adult Male Rats. Frontiers in neuroanatomy. vol 14. 2021-07-15. PMID:32903737. |
furthermore, a significant number of microglia with a dystrophic morphology were observed in ethanol-exposed tissue, accompanied by a significant decrease in brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2021-07-15 |
2023-08-13 |
rat |
| Kanishk Luhach, Giriraj T Kulkarni, Vijay P Singh, Bhupesh Sharm. Effect of papaverine on developmental hyperserotonemia induced autism spectrum disorder related behavioural phenotypes by altering markers of neuronal function, inflammation, and oxidative stress in rats. Clinical and experimental pharmacology & physiology. vol 48. issue 4. 2021-07-13. PMID:33480092. |
also, effects on important biochemical markers related with neuronal function (brain-derived neurotrophic factor (bdnf)-neuronal survival and phosphorylated-camp response element binding protein (pcreb)-neuronal transcription factor), brain inflammation (interleukin (il)-6, il-10 and tumour necrosis factor (tnf)-α) and brain oxidative stress (tbars and gsh) were studied in important brain areas (frontal cortex, cerebellum, hippocampus and striatum). |
2021-07-13 |
2023-08-13 |
rat |
| Mohammad Rumman, Shivani Pandey, Babita Singh, Mrinal Gupta, Saba Ubaid, Abbas Ali Mahd. Genistein Prevents Hypoxia-Induced Cognitive Dysfunctions by Ameliorating Oxidative Stress and Inflammation in the Hippocampus. Neurotoxicity research. vol 39. issue 4. 2021-07-13. PMID:33740236. |
finally, ge treatment enhanced the expression of neuroprotective genes including bdnf, creb, cbp, and igf1 in the hippocampus of amnesic mice. |
2021-07-13 |
2023-08-13 |
mouse |
| Anita Mihaylova, Nina Doncheva, Hristina Zlatanova, Delian Delev, Mariya Ivanovska, Yvetta Koeva, Marianna Murdjeva, Ilia Kostadino. Dopaminergic agonist pramipexole improves memory and increases IL-10 production in LPS-challenged rats. Iranian journal of basic medical sciences. vol 24. issue 5. 2021-07-13. PMID:34249258. |
in the current study, we investigated the effect of pramipexole (pmx) on memory functions, hippocampal amyloid deposition, serum cytokines, and brain-derived neurotrophic factor (bdnf) levels in lipopolysaccharide (lps) challenged-rats. |
2021-07-13 |
2023-08-13 |
rat |
| Wei Guan, Jiang-Hong Gu, Chun-Hui Ji, Yue Liu, Wen-Qian Tang, Yao Wang, Bo Jian. Xanthoceraside administration produces significant antidepressant effects in mice through activation of the hippocampal BDNF signaling pathway. Neuroscience letters. vol 757. 2021-07-12. PMID:34058291. |
xanthoceraside administration produces significant antidepressant effects in mice through activation of the hippocampal bdnf signaling pathway. |
2021-07-12 |
2023-08-13 |
mouse |
| Wei Guan, Jiang-Hong Gu, Chun-Hui Ji, Yue Liu, Wen-Qian Tang, Yao Wang, Bo Jian. Xanthoceraside administration produces significant antidepressant effects in mice through activation of the hippocampal BDNF signaling pathway. Neuroscience letters. vol 757. 2021-07-12. PMID:34058291. |
the effects of xan treatment on the hippocampal brain-derived neurotrophic factor (bdnf) signaling pathway and neurogenesis were examined. |
2021-07-12 |
2023-08-13 |
mouse |
| Wei Guan, Jiang-Hong Gu, Chun-Hui Ji, Yue Liu, Wen-Qian Tang, Yao Wang, Bo Jian. Xanthoceraside administration produces significant antidepressant effects in mice through activation of the hippocampal BDNF signaling pathway. Neuroscience letters. vol 757. 2021-07-12. PMID:34058291. |
xan treatment also significantly prevented the decreasing effects of cums on the hippocampal bdnf signaling and neurogenesis. |
2021-07-12 |
2023-08-13 |
mouse |
| Wei Guan, Jiang-Hong Gu, Chun-Hui Ji, Yue Liu, Wen-Qian Tang, Yao Wang, Bo Jian. Xanthoceraside administration produces significant antidepressant effects in mice through activation of the hippocampal BDNF signaling pathway. Neuroscience letters. vol 757. 2021-07-12. PMID:34058291. |
collectively, these findings indicate that xan possesses antidepressant effects in mice which are mediated by activation of hippocampal bdnf signaling pathway, thus providing the first evidence that xan can be a potential antidepressant candidate. |
2021-07-12 |
2023-08-13 |
mouse |
| Ayse Cigel, Oya Sayin, Seren Gulsen Gurgen, Atac Sonme. Long term neuroprotective effects of acute single dose MK-801treatment against traumatic brain injury in immature rats. Neuropeptides. vol 88. 2021-07-12. PMID:34098454. |
histopathological and immunohistochemical evaluations showed that treatment with mk-801 significantly ameliorated the trauma-induced hippocampal neuron loss and increased bdnf, ngf, nmda-r, gfap expressions in ca1, ca3, and dg hippocampal regions. |
2021-07-12 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
given the well-known effects of physical activity and sex hormones on cognitive functions and brain-derived neurotrophic factor (bdnf), the present study examined the effects of treadmill exercise, sex hormones, and the combined treatment on learning and memory and hippocampal bdnf levels in transient congenital hypothyroid rats. |
2021-07-08 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
on pnds 48-55, spatial learning and memory of all rats tested in the water maze, which followed by measurement of bdnf in the hippocampus. |
2021-07-08 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
results showed that developmental hypothyroidism induced significant deficits in spatial learning and memory and hippocampal bdnf in both male and female rats. |
2021-07-08 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
in both male and female hypothyroid rats, exercise and exercise plus sex hormones, but not sex hormones alone alleviated learning and memory deficits and all treatments (exercise, sex hormones, and the combined treatment) increased hippocampal bdnf. |
2021-07-08 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
these disconnects in the effects of exercise, sex hormones and the combined treatment on behavioral and neurochemical outcomes suggest that a neurochemical mechanism other than hippocampal bdnf might contribute in the ameliorating effects of exercise on learning and memory deficits induced by developmental thyroid hormone insufficiency. |
2021-07-08 |
2023-08-13 |
rat |
| Mamoru Fukuchi, Ryohei Saito, Shojiro Maki, Nami Hagiwara, Yumena Nakajima, Satoru Mitazaki, Hironori Izumi, Hisashi Mor. Visualization of activity-regulated BDNF expression in the living mouse brain using non-invasive near-infrared bioluminescence imaging. Molecular brain. vol 13. issue 1. 2021-07-07. PMID:32894176. |
we successfully visualized kainic acid-induced bdnf expression in the hippocampus and sensory stimulation-induced bdnf expression in the visual cortex. |
2021-07-07 |
2023-08-13 |
mouse |
| Eman Soliman, Nariman Essmat, Mona F Mahmoud, Amr A A Mahmou. Impact of some oral hypoglycemic agents on type 2 diabetes-associated depression and reserpine-induced depression in rats: the role of brain oxidative stress and inflammation. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 8. 2021-07-06. PMID:32077986. |
antidiabetic agents reduced diabetes-associated depression as indicated by the reduction in the immobility time in the forced swim test, elevation of cortical and hippocampal serotonin and brain-derived neurotrophic factor (bdnf), and the increase in serum β-amyloid 1-42 (aβ1-42) levels. |
2021-07-06 |
2023-08-13 |
rat |
| Ju Hwan Kim, Kyung Hwun Chung, Yeong Ran Hwang, Hye Ran Park, Hee Jung Kim, Hyung-Gun Kim, Hak Rim Ki. Exposure to RF-EMF Alters Postsynaptic Structure and Hinders Neurite Outgrowth in Developing Hippocampal Neurons of Early Postnatal Mice. International journal of molecular sciences. vol 22. issue 10. 2021-07-02. PMID:34069478. |
decreased bdnf expression was restricted to the soma and was not observed in neurites of hippocampal neurons following rf-emf exposure. |
2021-07-02 |
2023-08-13 |
mouse |
| Watcharin N Sovijit, Watcharee E Sovijit, Shaoxia Pu, Kento Usuda, Ryo Inoue, Gen Watanabe, Hirohito Yamaguchi, Kentaro Nagaok. Ovarian progesterone suppresses depression and anxiety-like behaviors by increasing the Lactobacillus population of gut microbiota in ovariectomized mice. Neuroscience research. vol 168. 2021-06-29. PMID:31022413. |
in addition, administration of lactobacillus (l.) reuteri that was increased by progesterone also reduced the depressant behavior in ovx mice, and bdnf gene expression was elevated by progesterone treatment and l. reuteri administration in the hippocampus. |
2021-06-29 |
2023-08-13 |
mouse |
| Amanda Della Giustina, Mariana Pereira de Souza Goldim, Lucinéia Gainski Danielski, Leandro Garbossa, Aloir Neri Oliveira Junior, Thainá Cidreira, Taís Denicol, Sandra Bonfante, Naiana da Rosa, Jucélia Jeremias Fortunato, Juliete Palandi, Bruna Hoffmann de Oliveira, Daniel Fernandes Martins, Franciane Bobinski, Michelle Garcez, Tatiani Bellettini-Santos, Josiane Budni, Gabriela Colpo, Giselli Scaini, Vijayasree V Giridharan, Tatiana Barichello, Fabricia Petronilh. Lipoic Acid and Fish Oil Combination Potentiates Neuroinflammation and Oxidative Stress Regulation and Prevents Cognitive Decline of Rats After Sepsis. Molecular neurobiology. vol 57. issue 11. 2021-06-29. PMID:32743736. |
the combination enhanced catalase activity in the prefrontal cortex and hippocampus, elevated bdnf levels in all structures, and prevented behavioral impairment. |
2021-06-29 |
2023-08-13 |
rat |