| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Zafra, B Hengerer, J Leibrock, H Thoenen, D Lindhol. Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. The EMBO journal. vol 9. issue 11. 1990-11-21. PMID:2170117. |
after we had demonstrated that depolarization with high potassium (50 mm) resulted in an increase in the levels of both bdnf and ngf mrnas in cultures of hippocampal neurons, we investigated the effect of a large number of transmitter substances. |
1990-11-21 |
2023-08-11 |
rat |
| F Zafra, B Hengerer, J Leibrock, H Thoenen, D Lindhol. Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. The EMBO journal. vol 9. issue 11. 1990-11-21. PMID:2170117. |
kainic acid also elevated levels of bdnf and ngf mrnas in rat hippocampus and cortex in vivo. |
1990-11-21 |
2023-08-11 |
rat |
| H S Phillips, J M Hains, G R Laramee, A Rosenthal, J W Winslo. Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons. Science (New York, N.Y.). vol 250. issue 4978. 1990-11-14. PMID:1688328. |
cells hybridizing intensely to antisense bdnf probe were located throughout the major targets of the rat basal forebrain cholinergic system, that is, the hippocampus, amygdala, and neocortex. |
1990-11-14 |
2023-08-11 |
human |
| H S Phillips, J M Hains, G R Laramee, A Rosenthal, J W Winslo. Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons. Science (New York, N.Y.). vol 250. issue 4978. 1990-11-14. PMID:1688328. |
in human hippocampus, cells expressing bdnf mrna are distributed in a fashion similar to that observed in the rat. |
1990-11-14 |
2023-08-11 |
human |
| P Ernfors, C F Ibáñez, T Ebendal, L Olson, H Persso. Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 14. 1990-08-23. PMID:2164684. |
we have used a pool of degenerate oligonucleotides representing all possible codons in regions of homology between brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf) to prime rat hippocampal cdnas in the polymerase chain reaction. |
1990-08-23 |
2023-08-11 |
rat |
| P Ernfors, C F Ibáñez, T Ebendal, L Olson, H Persso. Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 14. 1990-08-23. PMID:2164684. |
the amplified dna included a product with significant similarity to ngf and bdnf, which was used to isolate a 1020-nucleotide-long cdna from a rat hippocampal library. |
1990-08-23 |
2023-08-11 |
rat |
| M Hofer, S R Pagliusi, A Hohn, J Leibrock, Y A Bard. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. The EMBO journal. vol 9. issue 8. 1990-08-22. PMID:2369898. |
all brain regions examined were found to contain substantial amounts of bdnf mrna, the highest levels being found in the hippocampus followed by the cerebral cortex. |
1990-08-22 |
2023-08-11 |
mouse |
| M Hofer, S R Pagliusi, A Hohn, J Leibrock, Y A Bard. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. The EMBO journal. vol 9. issue 8. 1990-08-22. PMID:2369898. |
in the hippocampus, which is also the site of highest nerve growth factor (ngf) gene expression in the central nervous system (cns), there is approximately 50-fold more bdnf mrna than ngf mrna. |
1990-08-22 |
2023-08-11 |
mouse |
| M Hofer, S R Pagliusi, A Hohn, J Leibrock, Y A Bard. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. The EMBO journal. vol 9. issue 8. 1990-08-22. PMID:2369898. |
the bdnf mrna was localized by in situ hybridization in hippocampal neurons (pyramidal and granule cells). |
1990-08-22 |
2023-08-11 |
mouse |